Page last updated: 2024-09-03

gi 90291 and remifentanil

gi 90291 has been researched along with remifentanil in 9 studies

Compound Research Comparison

Studies
(gi 90291)
Trials
(gi 90291)
Recent Studies (post-2010)
(gi 90291)
Studies
(remifentanil)
Trials
(remifentanil)
Recent Studies (post-2010) (remifentanil)
10103,8301,6441,886

Protein Interaction Comparison

ProteinTaxonomygi 90291 (IC50)remifentanil (IC50)
Mu-type opioid receptorRattus norvegicus (Norway rat)0.0006

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (88.89)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bilotta, JM; Brackeen, MF; Feldman, PL; James, MK; Johnson, MR; Lahey, AP; Leighton, HJ; Lutz, MW; Schuster, SV1
Rosow, C1
Hoke, JF; Hug, CC; Muir, KT; Sebel, PS; Westmoreland, CL1
Connors, PM; Dershwitz, M; Dienstag, JL; Hoke, JF; Michałowski, P; Muir, KT; Rosow, CE1
Cunningham, F; Hoffman, WE; Hoke, JF; James, MK; Muir, KT1
Connors, PM; Dershwitz, M; Glass, PS; Hoke, JF; Malthouse-Dufore, S; Martel, D; Michałowski, P; Muir, KT; Rosow, CE; Rubin, N; Shlugman, D1
Cox, EH; Danhof, M; Gubbens-Stibbe, JM; Langemeijer, MW; Muir, KT1
Archer, S; Frazer, N; Gupta, SK; Muir, KT; Navapurkar, VU; Park, GR1
Davis, PJ; Dear Gd, GL; Ginsberg, B; Henson, LG; Huffman, C; McGowan, FX; Muir, KT; Ross, AK; Stiller, RD1

Trials

1 trial(s) available for gi 90291 and remifentanil

ArticleYear
Pharmacokinetics and pharmacodynamics of remifentanil in volunteer subjects with severe liver disease.
    Anesthesiology, 1996, Volume: 84, Issue:4

    Topics: Adult; Analgesics, Opioid; Female; Humans; Liver Diseases; Male; Middle Aged; Piperidines; Remifentanil

1996

Other Studies

8 other study(ies) available for gi 90291 and remifentanil

ArticleYear
Design, synthesis, and pharmacological evaluation of ultrashort- to long-acting opioid analgetics.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:7

    Topics: Analgesics; Anilides; Animals; Chemical Phenomena; Chemistry; Drug Evaluation, Preclinical; Guinea Pigs; Humans; Male; Piperidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Time Factors

1991
Remifentanil: a unique opioid analgesic.
    Anesthesiology, 1993, Volume: 79, Issue:5

    Topics: Analgesics, Opioid; Humans; Infusions, Intravenous; Piperidines; Remifentanil

1993
Pharmacokinetics of remifentanil (GI87084B) and its major metabolite (GI90291) in patients undergoing elective inpatient surgery.
    Anesthesiology, 1993, Volume: 79, Issue:5

    Topics: Adolescent; Adult; Analgesics, Opioid; Elective Surgical Procedures; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Piperidines; Remifentanil; Time Factors

1993
Comparative pharmacokinetics and pharmacodynamics of remifentanil, its principle metabolite (GR90291) and alfentanil in dogs.
    The Journal of pharmacology and experimental therapeutics, 1997, Volume: 281, Issue:1

    Topics: Alfentanil; Analgesics, Opioid; Animals; Dogs; Dose-Response Relationship, Drug; Electroencephalography; Male; Piperidines; Remifentanil

1997
Pharmacokinetics and pharmacodynamics of remifentanil in persons with renal failure compared with healthy volunteers.
    Anesthesiology, 1997, Volume: 87, Issue:3

    Topics: Analgesics, Opioid; Female; Humans; Male; Piperidines; Remifentanil; Renal Dialysis; Renal Insufficiency

1997
The comparative pharmacodynamics of remifentanil and its metabolite, GR90291, in a rat electroencephalographic model.
    Anesthesiology, 1999, Volume: 90, Issue:2

    Topics: Analgesics, Opioid; Anesthetics, Intravenous; Animals; Brain; Drug Interactions; Infusions, Intravenous; Male; Piperidines; Rats; Rats, Wistar; Remifentanil

1999
Metabolism of remifentanil during liver transplantation.
    British journal of anaesthesia, 1998, Volume: 81, Issue:6

    Topics: Adolescent; Adult; Analgesics, Opioid; Female; Half-Life; Humans; Intraoperative Care; Liver Transplantation; Lung; Male; Middle Aged; Piperidines; Remifentanil

1998
Pharmacokinetics of remifentanil in anesthetized pediatric patients undergoing elective surgery or diagnostic procedures.
    Anesthesia and analgesia, 2001, Volume: 93, Issue:6

    Topics: Adolescent; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Blood Pressure; Child; Child, Preschool; Elective Surgical Procedures; Female; Heart Rate; Humans; Hypotension; Infant; Infant, Newborn; Linear Models; Male; Piperidines; Remifentanil

2001