gi-129471 and batimastat

gi-129471 has been researched along with batimastat* in 1 studies

Other Studies

1 other study(ies) available for gi-129471 and batimastat

Article	Year
Selective inhibition of low affinity IgE receptor (CD23) processing. Bioorganic & medicinal chemistry letters, 1998, Jan-06, Volume: 8, Issue:1 A series of hydroxamic acids related to the non-selective matrix metalloproteinase inhibitor Batimastat has been prepared, some members of which are potent inhibitors of the processing of the low affinity IgE receptor (CD 23). Increased activity is obtained by appropriate substitution at the alpha-position, whilst selectivity is gained by use of a P1' benzyl group in conjunction with a C-terminal primary amide. Topics: Hydroxamic Acids; Phenylalanine; Protease Inhibitors; Protein Processing, Post-Translational; Receptors, IgE; Structure-Activity Relationship; Thiophenes	1998

Article

Year

Selective inhibition of low affinity IgE receptor (CD23) processing.

Bioorganic & medicinal chemistry letters, 1998, Jan-06, Volume: 8, Issue:1

A series of hydroxamic acids related to the non-selective matrix metalloproteinase inhibitor Batimastat has been prepared, some members of which are potent inhibitors of the processing of the low affinity IgE receptor (CD 23). Increased activity is obtained by appropriate substitution at the alpha-position, whilst selectivity is gained by use of a P1' benzyl group in conjunction with a C-terminal primary amide.

Topics: Hydroxamic Acids; Phenylalanine; Protease Inhibitors; Protein Processing, Post-Translational; Receptors, IgE; Structure-Activity Relationship; Thiophenes

1998