Page last updated: 2024-08-24

geranylgeraniol and squalene

geranylgeraniol has been researched along with squalene in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (44.44)18.2507
2000's1 (11.11)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Corsini, A; Fumagalli, R; Gabbiani, G; Mazzotti, M; Paoletti, R; Raiteri, M; Soma, MR1
Favre, G; Miquel, K; Pradines, A1
Durham, SK; Flint, OP; Gregg, RE; Masters, BA1
Fisher, JE; Halasy, JM; Hughes, DE; Luckman, SP; Masarachia, PJ; Reszka, AA; Rodan, GA; Rogers, MJ; Russell, RG; Wesolowski, G1
Hirai, M; Kawaguchi, T; Kondo, A; Muramatsu, M; Muramoto, N; Obata, S; Ohto, C; Sakuradani, E; Shimizu, S; Takahashi, H; Tokuhiro, K1
Guo, LQ; Lin, JF; Ren, T; Wang, JR; You, LF1
Hagelauer, N; Pabst, AM; Walter, C; Ziebart, T1
Fukushima, S; Minegaki, T; Morioka, C; Nishiguchi, K; Takanashi, H; Tsuji, S; Tsujimoto, M; Uno, J; Watanabe, A; Yamamoto, S1
McCully, KS1

Reviews

1 review(s) available for geranylgeraniol and squalene

ArticleYear
Chemical Pathology of Homocysteine VIII. Effects of Tocotrienol, Geranylgeraniol, and Squalene on Thioretinaco Ozonide, Mitochondrial Permeability, and Oxidative Phosphorylation in Arteriosclerosis, Cancer, Neurodegeneration and Aging.
    Annals of clinical and laboratory science, 2020, Volume: 50, Issue:5

    Topics: Aging; Animals; Arteriosclerosis; Cholesterol; Diterpenes; Homocysteine; Humans; Mitochondria; NAD; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Phosphorylation; Permeability; Squalene; Tocotrienols; Vitamin B 12

2020

Other Studies

8 other study(ies) available for geranylgeraniol and squalene

ArticleYear
Relationship between mevalonate pathway and arterial myocyte proliferation: in vitro studies with inhibitors of HMG-CoA reductase.
    Atherosclerosis, 1993, Volume: 101, Issue:1

    Topics: Acyclic Monoterpenes; Animals; Aorta; Cell Division; Cells, Cultured; Cholesterol; Diterpenes; Dose-Response Relationship, Drug; Farnesol; Fatty Acids, Monounsaturated; Femoral Artery; Fluvastatin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Lovastatin; Male; Mevalonic Acid; Muscle, Smooth, Vascular; Pravastatin; Rats; Rats, Sprague-Dawley; Simvastatin; Squalene; Terpenes

1993
Farnesol and geranylgeraniol induce actin cytoskeleton disorganization and apoptosis in A549 lung adenocarcinoma cells.
    Biochemical and biophysical research communications, 1996, Aug-23, Volume: 225, Issue:3

    Topics: Actins; Acyclic Monoterpenes; Apoptosis; Cholesterol; Cytoskeleton; Desmosterol; Diterpenes; Enzyme Inhibitors; Farnesol; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Squalene; Terpenes; Tumor Cells, Cultured

1996
Inhibition of cholesterol synthesis by squalene synthase inhibitors does not induce myotoxicity in vitro.
    Toxicology and applied pharmacology, 1997, Volume: 145, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Anticholesteremic Agents; Butylamines; Cells, Cultured; Cholesterol; Diterpenes; Enzyme Inhibitors; Farnesol; Farnesyl-Diphosphate Farnesyltransferase; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; L-Lactate Dehydrogenase; Lovastatin; Mevalonic Acid; Muscle, Skeletal; Pravastatin; Pregnancy; Prodrugs; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Squalene; Sulfonic Acids

1997
Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Jan-05, Volume: 96, Issue:1

    Topics: Alendronate; Animals; Bone Resorption; Cell Differentiation; Cells, Cultured; Cholesterol; Clodronic Acid; Diterpenes; Enzyme Activation; Farnesol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Mice; Osteoclasts; Protein Kinases; Rabbits; Skull; Squalene

1999
Overproduction of geranylgeraniol by metabolically engineered Saccharomyces cerevisiae.
    Applied and environmental microbiology, 2009, Volume: 75, Issue:17

    Topics: Biosynthetic Pathways; Diterpenes; Farnesyltranstransferase; Genetic Engineering; Geranyltranstransferase; Hydroxymethylglutaryl-CoA-Reductases, NADP-dependent; Membrane Proteins; Models, Biological; Pyrophosphatases; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Squalene

2009
Overproduction of geranylgeraniol in Coprinopsis cinerea by the expression of geranylgeranyl diphosphate synthase gene.
    Journal of basic microbiology, 2014, Volume: 54, Issue:12

    Topics: Basidiomycota; Diterpenes; Ergosterol; Farnesyltranstransferase; Squalene; Taxus; Transformation, Genetic

2014
Bisphosphonates inhibit cell functions of HUVECs, fibroblasts and osteogenic cells via inhibition of protein geranylgeranylation.
    Clinical oral investigations, 2015, Volume: 19, Issue:5

    Topics: Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Cell Movement; Cell Survival; Cells, Cultured; Cyclohexenes; Diphosphonates; Diterpenes; Endothelial Cells; Eugenol; Farnesol; Fibroblasts; Humans; Imidazoles; Limonene; Menthol; Osteogenesis; Protein Prenylation; Recurrence; Squalene; Terpenes; Umbilical Veins; Zoledronic Acid

2015
Effects of bisphosphonates on human esophageal squamous cell carcinoma cell survival.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2016, Volume: 29, Issue:6

    Topics: Annexins; Apoptosis; Bone Density Conservation Agents; Carcinoma, Squamous Cell; Caspase 3; Caspase 7; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Cyclin D1; Diphosphonates; Diterpenes; Drug Screening Assays, Antitumor; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Farnesol; G1 Phase Cell Cycle Checkpoints; Humans; Squalene

2016