Page last updated: 2024-08-24

geranylgeraniol and geranylgeranyl pyrophosphate

geranylgeraniol has been researched along with geranylgeranyl pyrophosphate in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (16.67)	18.7374
1990's	3 (25.00)	18.2507
2000's	4 (33.33)	29.6817
2010's	1 (8.33)	24.3611
2020's	2 (16.67)	2.80

Authors

Authors	Studies
Schultz, G; Soll, J	1
Benz, J; Guthoff, C; Rüdiger, W	1
Knöss, W; Reuter, B	1
Andres, DA; Crick, DC; Danesi, R; Macchia, M; Waechter, CJ	1
Foster, BA; Ghosh, PM; Ghosh-Choudhury, N; Greenberg, NM; Kreisberg, JI; Mott, GE; Moyer, ML; Thomas, CA	1
Bannerman, DD; Hamilton, AD; Harlan, JM; Li, X; Liu, L; Sebti, SM; Tupper, JC; Winn, RK	1
Ahmad, S; Ahmed, Z; Bhatia, V; Haskard, DO; Kinderlerer, A; Lidington, EA; Mankoff, R; Mason, JC; Randi, AM	1
Karperien, M; Löwik, C; Papapoulos, S; van Beek, E	1
Berger, S; Connor, AM; Keystone, EC; Narendran, A	1
Coates, DE; Cullinan, MP; Drummond, BK; Milne, T; Seymour, GJ; Zafar, S	1
Fruman, DA; Juarez, D	1
DeBose-Boyd, RA; Elsabrouty, R; Hwang, S; Jo, Y; Jun, DJ	1

Reviews

1 review(s) available for geranylgeraniol and geranylgeranyl pyrophosphate

Article	Year
Targeting the Mevalonate Pathway in Cancer. Trends in cancer, 2021, Volume: 7, Issue:6 Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Diterpenes; Farnesyltranstransferase; Feeding Behavior; Food-Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metabolic Networks and Pathways; Mevalonic Acid; Mice; Neoplasms; Pinocytosis; Polyisoprenyl Phosphates; Prenylation	2021

Article

Year

Targeting the Mevalonate Pathway in Cancer.

Trends in cancer, 2021, Volume: 7, Issue:6

Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Diterpenes; Farnesyltranstransferase; Feeding Behavior; Food-Drug Interactions; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Metabolic Networks and Pathways; Mevalonic Acid; Mice; Neoplasms; Pinocytosis; Polyisoprenyl Phosphates; Prenylation

2021

Other Studies

11 other study(ies) available for geranylgeraniol and geranylgeranyl pyrophosphate

Article	Year
Phytol synthesis from geranylgeraniol in spinach chloroplasts. Biochemical and biophysical research communications, 1981, Apr-15, Volume: 99, Issue:3 Topics: Chlorophyllides; Chloroplasts; Diterpenes; Phytol; Polyisoprenyl Phosphates	1981
Detection and partial characterization of activity of chlorophyll synthetase in etioplast membranes. European journal of biochemistry, 1980, Volume: 109, Issue:1 Topics: Carbon-Oxygen Ligases; Chlorophyllides; Chromatography, High Pressure Liquid; Diterpenes; Edible Grain; Kinetics; Ligases; Plants; Polyisoprenyl Phosphates; Substrate Specificity	1980
Biosynthesis of [14C]geranylgeranyldiphosphate by a prenyl transferase system from a mutant strain of Gibberella fujikuroi. Analytical biochemistry, 1996, Aug-01, Volume: 239, Issue:2 Topics: Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Dimethylallyltranstransferase; Diterpenes; Gibberella; Hydrolysis; Mevalonic Acid; Mutagenesis; Oxidoreductases; Polyisoprenyl Phosphates	1996
Geranylgeraniol overcomes the block of cell proliferation by lovastatin in C6 glioma cells. Journal of neurochemistry, 1998, Volume: 70, Issue:6 Topics: Animals; Cell Division; Diterpenes; Electrophoresis, Polyacrylamide Gel; Farnesol; Glioma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mevalonic Acid; Molecular Weight; Nerve Tissue Proteins; Polyisoprenyl Phosphates; Protein Prenylation; Rats; Thymidine; Tumor Cells, Cultured	1998
Role of RhoA activation in the growth and morphology of a murine prostate tumor cell line. Oncogene, 1999, Jul-15, Volume: 18, Issue:28 Topics: Actin Cytoskeleton; Adenocarcinoma; Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Apoptosis; Cell Adhesion; Cell Division; Cell Size; Diterpenes; Drug Interactions; Enzyme Activation; Farnesol; G1 Phase; Genes, ras; GTP-Binding Proteins; Guanosine Triphosphate; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Male; Mevalonic Acid; Mice; Mice, Transgenic; Polyisoprenyl Phosphates; Prostatic Neoplasms; Protein Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); rac GTP-Binding Proteins; rhoA GTP-Binding Protein; Sesquiterpenes; Tumor Cells, Cultured	1999
Inhibition of protein geranylgeranylation and RhoA/RhoA kinase pathway induces apoptosis in human endothelial cells. The Journal of biological chemistry, 2002, May-03, Volume: 277, Issue:18 Topics: Apoptosis; Benzamides; Caspase 3; Caspases; Cell Death; Cells, Cultured; Diterpenes; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracellular Signaling Peptides and Proteins; Lovastatin; Methionine; Polyisoprenyl Phosphates; Protein Prenylation; Protein Serine-Threonine Kinases; rho-Associated Kinases; rhoA GTP-Binding Protein; Umbilical Veins	2002
Statin-induced expression of decay-accelerating factor protects vascular endothelium against complement-mediated injury. Circulation research, 2002, Oct-18, Volume: 91, Issue:8 Topics: Atorvastatin; CD55 Antigens; Cell Line; Cells, Cultured; Complement Activation; Complement C3; Cytoprotection; Diterpenes; Endothelium, Vascular; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Nitric Oxide; Phosphatidylinositol 3-Kinases; Polyisoprenyl Phosphates; Protein Kinase C; Pyrroles; rho GTP-Binding Proteins; RNA, Messenger; Simvastatin; Up-Regulation	2002
Independent pathways in the modulation of osteoclastic resorption by intermediates of the mevalonate biosynthetic pathway: the role of the retinoic acid receptor. Bone, 2006, Volume: 38, Issue:2 Topics: Animals; Bone and Bones; Bone Density Conservation Agents; Bone Resorption; Calcium; Diphosphonates; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Female; Ibandronic Acid; Mevalonic Acid; Mice; Osteoclasts; Polyisoprenyl Phosphates; Pregnancy; Protein Prenylation; Receptors, Retinoic Acid	2006
Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts. Arthritis research & therapy, 2006, Volume: 8, Issue:4 Topics: Apoptosis; Arthritis, Rheumatoid; Biological Transport; Cell Survival; Cells, Cultured; Cytoplasm; Diterpenes; Fibroblasts; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Membrane Proteins; Osteoarthritis; Polyisoprenyl Phosphates; Proto-Oncogene Proteins c-akt; rac1 GTP-Binding Protein; RNA, Small Interfering; Synovial Membrane; Tissue Distribution; Tumor Necrosis Factor-alpha	2006
Zoledronic acid and geranylgeraniol regulate cellular behaviour and angiogenic gene expression in human gingival fibroblasts. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2014, Volume: 43, Issue:9 Topics: Adult; Apoptosis; Bone Density Conservation Agents; Bone Morphogenetic Protein 2; Cell Culture Techniques; Cell Survival; Cells, Cultured; Diphosphonates; Diterpenes; Epiregulin; Farnesol; Female; Fibroblasts; Gene Expression Regulation; Gingiva; Humans; Imidazoles; Interferon-alpha; Mevalonic Acid; Microscopy, Electron, Transmission; Middle Aged; Neovascularization, Physiologic; Polyisoprenyl Phosphates; rhoB GTP-Binding Protein; Sesquiterpenes; Signal Transduction; Vascular Endothelial Growth Factor A; Zoledronic Acid	2014
Type 1 polyisoprenoid diphosphate phosphatase modulates geranylgeranyl-mediated control of HMG CoA reductase and UBIAD1. eLife, 2021, 11-29, Volume: 10 Topics: Cell Line; Dimethylallyltranstransferase; Diterpenes; Endoplasmic Reticulum-Associated Degradation; Golgi Apparatus; Humans; Hydroxymethylglutaryl CoA Reductases; Phosphoric Monoester Hydrolases; Polyisoprenyl Phosphates	2021