Page last updated: 2024-08-23

gepirone and buspirone

gepirone has been researched along with buspirone in 87 studies

Research

Studies (87)

Timeframe	Studies, this research(%)	All Research%
pre-1990	38 (43.68)	18.7374
1990's	39 (44.83)	18.2507
2000's	8 (9.20)	29.6817
2010's	2 (2.30)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Glennon, RA; Lyon, RA; Naiman, NA; Titeler, M	1
New, JS; Riblet, LA; Taylor, DP; Temple, DL; Yevich, JP	1
Ashwell, MA; Beresford, A; O'Donnell, MM; Palma, R; Porte, A; Tandon, M; Vensel, D; Yang, D	1
Becker, OM; Chen, D; Cheruku, S; Dhanoa, DS; Fichman, M; Heifetz, A; Kauffman, M; Marantz, Y; Mohanty, P; Noiman, S; Nudelman, R; Shacham, S; Sharadendu, A	1
Cleves, AE; Jain, AN; Kirshner, D; Langham, JJ; Spitzer, R	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Talele, TT	1
Allen, T; Grahame-Smith, DG; Grasby, PM; Kelly, PA; Sharp, T	1
Balster, RL; Gold, LH	1
Gilbert, F; Pan, L	1
Heal, DJ; Hearson, M; Martin, KF; Phillips, I; Prow, MR	1
Rigdon, GC; Weatherspoon, JK	1
Kelder, D; Ross, SB	1
Moon, SL; Taylor, DP	1
Kennett, GA	1
Franklin, M	1
Eison, AS	1
Anderson, IM; Cowen, PJ; Grahame-Smith, DG	1
Balster, RL	1
Copp, JE; Robinson, DS; Schwiderski, UE	1
Yocca, FD	1
Murphy, DL; Pato, MT; Pigott, TA	1
Fischette, C; Hamik, A; Oksenberg, D; Peroutka, SJ	1
Sanger, DJ	1
Berridge, KC; Treit, D	1
Eison, AS; Margraf, RR; Wright, RN; Yocca, FD	1
Colpaert, FC; Millan, MJ	1
Davies, M; Fletcher, PJ	1
Demetrikopoulos, MK; Flaherty, CF; Grigson, PS; Krauss, KL; Rowan, GA; Weaver, MS	1
Bielenberg, GW; Burkhardt, M	1
Bardo, MT; Bowling, SL; McDougall, SA; Neisewander, JL	1
Barrett, JE; Harrod, C; Hoffmann, SM; Lei, Z; Mansbach, RS; Nader, MA; Witkin, JM	1
Nomura, Y; Okada, F; Tokumitsu, Y	1
Boyer, WF; Feighner, JP	1
Engel, JA; Hjorth, S; Söderpalm, B	1
Hirose, A; Kumasaka, Y; Nakamura, M; Shimizu, H; Tanaka, H; Tatsuno, T	1
Rodgers, RJ; Shepherd, JK	1
Alms, DR; Messina, M; Robinson, DS; Shrotriya, RC; Wickramaratne, P	1
Dixon, V; Gage-White, D; Guthrie, D; Matheson, GK; Rhoades, J; White, G	1
Eison, MS; Matheson, GK	1
Caccia, S; Fong, MH; Guiso, G	1
Eison, AS; Eison, MS; Riblet, LA; Stanley, M	1
Le Moal, M; Louilot, A; Simon, H	1
Barrett, JE; Mansbach, RS; Skolnick, P; Weissman, BA; Witkin, JM	1
Faktor, MI; Gliuske, EIu; Korneev, AIa	1
Gorzalka, BB; Mendelson, SD	1
Giral, P; Puech, AJ; Soubrie, P	1
Andrade, R; Nicoll, RA	1
Barrett, JE; Bolger, GT; Mansbach, RS; Skolnick, P; Weissman, B; Witkin, JM	1
Giral, P; Martin, P; Simon, P; Soubrié, P	1
Chan, TB; Faktor, MI; Korneev, AIa	1
Dourish, CT; Gilbert, F	1
Chamberlain, JK; DaVanzo, JP; McMillen, BA	1
Cassella, JV; Davis, M; Kehne, JH	1
Brazell, C; Gilbert, F; Stahl, SM; Tricklebank, MD	1
Gudelsky, GA; Koenig, JI; Meltzer, HY	1
Barrett, JE; Fleck-Kandath, C; Mansbach, RS	1
Bianchi, G; Caccia, S; Della Vedova, F; Garattini, S	1
Anderson, MC; Chung, E; Van Woert, MH	1
Brazell, C; Dourish, CT; Gilbert, F; McClue, S; Stahl, SM	1
Bianchi, G; Caccia, S	1
Skolnick, P; Weissman, BA; Youdim, MB	1
Geyer, MA; Mansbach, RS	1
Geiger, G; Grimes, D; Heaslip, RJ; Henry, DE; Lee, DK; Rimele, TJ	1
Blanchard, DC; Hendrie, CA; Hori, K; Rodgers, RJ	1
Barrett, JE; Mansbach, RS	1
Mattiace, LA; McMillen, BA	1
Gomita, Y; Oishi, R; Yamashita, S	1
Cullen, WK; Rowan, MJ	1
Matheson, GK; Michel, C; Pfeifer, DM; Weiberg, MB	1
Clement, ME; Escandon, NA; Harris, LT; McCall, RB	1
Farmen, RH; Pittman, KA; Sciacca, MA; Sostrin, MB; Tay, LK	1
Lum-Ragan, JT; Piercey, MF; Smith, MW	1
Korneyev, AY; Seredenin, SB	1
Jantos, H; Monti, JM; Reyes-Parada, M; Scorza, C; Silveira, R	1
Azzaro, AJ; Fox, JL; Johnson, EA	1
Bartolini, A; Galeotti, N; Ghelardini, C	1
Bauer, C; Blackbourne, J; Gage, D; Guthrie, D; Knowles, A; Matheson, GK; Michel, C; Weinzapfel, D	1
Allikmets, L; Harro, J; Matto, V; Otter, MH; Skrebuhhova, T; Sõukand, R	1
Fabre, LF; Fogelman, SM; Granda, BW; Grassi, JM; Greenblatt, DJ; Harmatz, JS; Kramer, SJ; Shader, RI; von Moltke, LL	1
Christ, G; Kaynan, A; Maayani, S; Melman, A; Rehman, J; Valcic, M	1
Olivares, E; Tripathi, B; Turek, FW; Van Reeth, O; Zhang, Y	1
Allikmets, L; Matto, V; Pruus, K; Rudissaar, R; Skrebuhhova-Malmros, T	1
Chilmonczyk, Z; Cybulski, J; Krajewski, KJ	1
Garteiz, DA; Giancarlo, GM; Greenblatt, DJ; Von Moltke, LL	1
Sitsen, JM; Timmer, CJ	1
Eckler, JR; Rabin, RA; Reissig, CJ; Winter, JC	1

Reviews

8 review(s) available for gepirone and buspirone

Article	Year
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry. Journal of medicinal chemistry, 2018, 03-22, Volume: 61, Issue:6 Topics: Animals; Biological Products; Chemistry, Pharmaceutical; Humans	2018
Buspirone and related compounds as alternative anxiolytics. Neuropeptides, 1991, Volume: 19 Suppl Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Binding Sites; Buspirone; Humans; Isoindoles; Piperazines; Pyrimidines; Receptors, Serotonin; Structure-Activity Relationship	1991
Mechanisms of serotonergic affect control. Advances in experimental medicine and biology, 1991, Volume: 294 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Buspirone; Conflict, Psychological; Depression; Down-Regulation; Feedback; Humans; Interpersonal Relations; Piperazines; Pyrimidines; Raphe Nuclei; Rats; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Tetrahydronaphthalenes	1991
Neuroendocrine effects of azapirones. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:3 Suppl Topics: Animals; Anti-Anxiety Agents; Buspirone; Dose-Response Relationship, Drug; Humans; Neurosecretory Systems; Pyrimidines; Receptors, Serotonin	1990
Abuse potential of buspirone and related drugs. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:3 Suppl Topics: Animals; Anti-Anxiety Agents; Buspirone; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Euphoria; Humans; Product Surveillance, Postmarketing; Pyrimidines; Rats; Substance-Related Disorders	1990
Neurochemistry and neurophysiology of buspirone and gepirone: interactions at presynaptic and postsynaptic 5-HT1A receptors. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:3 Suppl Topics: Animals; Anti-Anxiety Agents; Arousal; Brain; Buspirone; Hippocampus; Humans; Membrane Potentials; Pyrimidines; Raphe Nuclei; Receptors, Serotonin; Synapses; Synaptic Transmission	1990
Obsessive-compulsive disorder: treatment with serotonin-selective uptake inhibitors, azapirones, and other agents. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:3 Suppl Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Buspirone; Clinical Trials as Topic; Clomipramine; Double-Blind Method; Humans; Obsessive-Compulsive Disorder; Pyrimidines; Serotonin Antagonists	1990
Serotonin-1A anxiolytics: an overview. Psychopathology, 1989, Volume: 22 Suppl 1 Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Brain; Buspirone; Clinical Trials as Topic; Double-Blind Method; Humans; Isoindoles; Piperazines; Pyrimidines; Receptors, Serotonin	1989

Trials

8 trial(s) available for gepirone and buspirone

Article	Year
Buspirone and related compounds as alternative anxiolytics. Neuropeptides, 1991, Volume: 19 Suppl Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Binding Sites; Buspirone; Humans; Isoindoles; Piperazines; Pyrimidines; Receptors, Serotonin; Structure-Activity Relationship	1991
Abuse potential of buspirone and related drugs. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:3 Suppl Topics: Animals; Anti-Anxiety Agents; Buspirone; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Euphoria; Humans; Product Surveillance, Postmarketing; Pyrimidines; Rats; Substance-Related Disorders	1990
Symptom comorbidity in anxiety and depressive disorders. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:3 Suppl Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Buspirone; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Panic; Personality Assessment; Piperazines; Psychometrics; Pyrimidines; Randomized Controlled Trials as Topic; Triazoles	1990
Obsessive-compulsive disorder: treatment with serotonin-selective uptake inhibitors, azapirones, and other agents. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:3 Suppl Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Buspirone; Clinical Trials as Topic; Clomipramine; Double-Blind Method; Humans; Obsessive-Compulsive Disorder; Pyrimidines; Serotonin Antagonists	1990
Serotonin-1A anxiolytics: an overview. Psychopathology, 1989, Volume: 22 Suppl 1 Topics: Animals; Anti-Anxiety Agents; Anxiety Disorders; Brain; Buspirone; Clinical Trials as Topic; Double-Blind Method; Humans; Isoindoles; Piperazines; Pyrimidines; Receptors, Serotonin	1989
Serotonergic anxiolytics and treatment of depression. Psychopathology, 1989, Volume: 22 Suppl 1 Topics: Adult; Brain; Buspirone; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Female; Humans; Male; Psychological Tests; Pyrimidines; Random Allocation; Receptors, Serotonin	1989
Effect of food on the bioavailability of gepirone in humans. Journal of clinical pharmacology, 1993, Volume: 33, Issue:7 Topics: Administration, Oral; Adolescent; Adult; Anti-Anxiety Agents; Antidepressive Agents; Biological Availability; Buspirone; Fasting; Food; Humans; Male; Pyrimidines	1993
Pharmacokinetic evaluation of gepirone immediate-release capsules and gepirone extended-release tablets in healthy volunteers. Journal of pharmaceutical sciences, 2003, Volume: 92, Issue:9 Topics: Adult; Area Under Curve; Biological Availability; Buspirone; Capsules; Cross-Over Studies; Delayed-Action Preparations; Half-Life; Humans; Intestinal Absorption; Male; Pyrimidines; Serotonin Receptor Agonists; Tablets; Time Factors	2003

Other Studies

75 other study(ies) available for gepirone and buspirone

Article	Year
Arylpiperazine derivatives as high-affinity 5-HT1A serotonin ligands. Journal of medicinal chemistry, 1988, Volume: 31, Issue:10 Topics: Animals; Chemical Phenomena; Chemistry; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Structure-Activity Relationship	1988
Buspirone analogues. 1. Structure-activity relationships in a series of N-aryl- and heteroarylpiperazine derivatives. Journal of medicinal chemistry, 1983, Volume: 26, Issue:2 Topics: Animals; Anti-Anxiety Agents; Binding, Competitive; Buspirone; Corpus Striatum; Kinetics; Male; Models, Molecular; Molecular Conformation; Piperazines; Pyrimidines; Rats; Receptors, Dopamine; Spiperone; Structure-Activity Relationship	1983
The design and preparation of metabolically protected new arylpiperazine 5-HT1A ligands. Bioorganic & medicinal chemistry letters, 2004, Apr-05, Volume: 14, Issue:7 Topics: Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Design; Humans; Ligands; Piperazines; Receptor, Serotonin, 5-HT1A; Serotonin Agents	2004
An integrated in silico 3D model-driven discovery of a novel, potent, and selective amidosulfonamide 5-HT1A agonist (PRX-00023) for the treatment of anxiety and depression. Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Binding, Competitive; Biological Availability; Cell Line; Clinical Trials, Phase I as Topic; Dogs; Drug Design; Half-Life; Humans; In Vitro Techniques; Male; Mice; Microsomes, Liver; Models, Molecular; Patch-Clamp Techniques; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Serotonin 5-HT1 Receptor Agonists; Structure-Activity Relationship; Sulfonamides	2006
Physical binding pocket induction for affinity prediction. Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19 Topics: Binding Sites; Ligands; Models, Molecular; Neural Networks, Computer; Peptide Fragments; Protein Binding; Receptor, Serotonin, 5-HT1A	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Effects of the 5-HT1A partial agonists gepirone, ipsapirone and buspirone on local cerebral glucose utilization in the conscious rat. Psychopharmacology, 1992, Volume: 106, Issue:1 Topics: Animals; Anti-Anxiety Agents; Autoradiography; Behavior, Animal; Blood Pressure; Body Temperature; Brain Chemistry; Buspirone; Deoxyglucose; Glucose; Male; Pyrimidines; Rats; Rats, Inbred Strains	1992
Effects of buspirone and gepirone on i.v. cocaine self-administration in rhesus monkeys. Psychopharmacology, 1992, Volume: 108, Issue:3 Topics: Animals; Anti-Anxiety Agents; Behavior, Animal; Buspirone; Chlorpromazine; Cocaine; Conditioning, Operant; Injections, Intravenous; Macaca mulatta; Male; Pyrimidines; Reinforcement Schedule; Self Administration	1992
Activation of 5-HT1A receptor subtype in the paraventricular nuclei of the hypothalamus induces CRH and ACTH release in the rat. Neuroendocrinology, 1992, Volume: 56, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Buspirone; Corticotropin-Releasing Hormone; Male; Paraventricular Hypothalamic Nucleus; Pindolol; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Receptor Agonists	1992
Characterization of 8-OH-DPAT-induced hypothermia in mice as a 5-HT1A autoreceptor response and its evaluation as a model to selectively identify antidepressants. British journal of pharmacology, 1992, Volume: 107, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Antidepressive Agents; Body Temperature; Buspirone; Dose-Response Relationship, Drug; Down-Regulation; Hypothermia; Male; Mice; Mice, Inbred C57BL; Parasympatholytics; Pyrimidines; Receptors, Dopamine D2; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists	1992
5-Hydroxytryptamine 1a receptor agonists block prepulse inhibition of acoustic startle reflex. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acoustic Stimulation; Animals; Buspirone; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; Male; Methoxydimethyltryptamines; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Reflex, Startle; Schizophrenia; Serotonin Receptor Agonists	1992
Long lasting attenuation of 8-OH-DPAT-induced corticosterone secretion after a single injection of a 5-HT1A receptor agonist. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Corticosterone; Drug Interactions; Hydrocortisone; Injections; Male; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Serotonin Receptor Agonists; Time Factors	1992
Determination of plasma buspirone by high-performance liquid chromatography with coulometric detection. Journal of chromatography, 1990, Apr-06, Volume: 526, Issue:2 Topics: Anti-Anxiety Agents; Buspirone; Chromatography, High Pressure Liquid; Electrochemistry; Humans; Pyrimidines; Reference Standards	1990
Azapirones: history of development. Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:3 Suppl Topics: Animals; Anti-Anxiety Agents; Arousal; Behavior, Animal; Brain; Buspirone; Chemistry; History, 20th Century; Humans; Pyrimidines; Receptors, Serotonin; Structure-Activity Relationship	1990
Analysis of tandospirone (SM-3997) interactions with neurotransmitter receptor binding sites. Biological psychiatry, 1990, Jul-15, Volume: 28, Issue:2 Topics: Adenylyl Cyclases; Animals; Anti-Anxiety Agents; Binding, Competitive; Brain; Buspirone; Isoindoles; Male; Piperazines; Pyrimidines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, Dopamine; Receptors, Serotonin	1990
Effects of buspirone and related compounds on suppressed operant responding in rats. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 254, Issue:2 Topics: Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Buspirone; Chlordiazepoxide; Conditioning, Operant; Dioxanes; Idazoxan; Injections, Intraperitoneal; Male; Pyrimidines; Rats; Rats, Inbred Strains	1990
A comparison of benzodiazepine, serotonin, and dopamine agents in the taste-reactivity paradigm. Pharmacology, biochemistry, and behavior, 1990, Volume: 37, Issue:3 Topics: Amphetamine; Animals; Apomorphine; Benzodiazepines; Buspirone; Chlordiazepoxide; Diazepam; Dopamine Agents; Feeding Behavior; Haloperidol; Male; Pyrimidines; Quinine; Rats; Rats, Inbred Strains; Serotonin; Sucrose; Taste	1990
8-OH-DPAT and buspirone analogs inhibit the ketanserin-sensitive quipazine-induced head shake response in rats. Pharmacology, biochemistry, and behavior, 1990, Volume: 35, Issue:1 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Head; Ketanserin; Male; Naphthalenes; Pindolol; Pyrimidines; Quinolines; Quipazine; Rats; Rats, Inbred Strains; Receptors, Serotonin; Stereotyped Behavior; Tetrahydronaphthalenes	1990
Attenuation of opioid induced antinociception by 5-HT1A partial agonists in the rat. Neuropharmacology, 1990, Volume: 29, Issue:3 Topics: Alprenolol; Analgesics; Animals; Buspirone; Fentanyl; Male; Morphine; Narcotics; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Reaction Time; Receptors, Serotonin; Spiperone; Sufentanil	1990
The involvement of 5-hydroxytryptaminergic and dopaminergic mechanisms in the eating induced by buspirone, gepirone and ipsapirone. British journal of pharmacology, 1990, Volume: 99, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dopamine; Dose-Response Relationship, Drug; Eating; Fenclonine; Haloperidol; Male; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes	1990
Effect of serotonergic drugs on negative contrast in consummatory behavior. Pharmacology, biochemistry, and behavior, 1990, Volume: 36, Issue:4 Topics: Animals; Buspirone; Chlordiazepoxide; Cyproheptadine; Dose-Response Relationship, Drug; Ethanol; Feeding Behavior; Fenclonine; Injections, Intraperitoneal; Injections, Subcutaneous; Ketanserin; Male; Midazolam; Nucleus Accumbens; Piperidines; Pyrimidines; Rats; Rats, Inbred Strains; Ritanserin; Serotonin; Serotonin Antagonists	1990
5-hydroxytryptamine1A agonists. A new therapeutic principle for stroke treatment. Stroke, 1990, Volume: 21, Issue:12 Suppl Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Buspirone; Indoles; Ischemic Attack, Transient; Mice; Pyrimidines; Rats; Rats, Inbred F344; Receptors, Serotonin; Tetrahydronaphthalenes	1990
Conditioned taste aversion and place preference with buspirone and gepirone. Psychopharmacology, 1990, Volume: 100, Issue:4 Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Avoidance Learning; Brain Chemistry; Buspirone; Choice Behavior; Diazepam; Dopamine; Hydrazines; Male; Neurons; Nucleus Accumbens; Pyrimidines; Rats; Rats, Inbred Strains; Taste	1990
Behavioral studies with anxiolytic drugs. V. Behavioral and in vivo neurochemical analyses in pigeons of drugs that increase punished responding. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Buspirone; Chlordiazepoxide; Clozapine; Columbidae; Conditioning, Operant; Haloperidol; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Punishment; Pyrimidines	1988
Pertussis toxin attenuates 5-hydroxytryptamine1A receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in rat hippocampal membranes. Journal of neurochemistry, 1989, Volume: 52, Issue:5 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Buspirone; Cell Membrane; Colforsin; GTP-Binding Proteins; Hippocampus; Male; Membrane Proteins; Molecular Weight; Pertussis Toxin; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Virulence Factors, Bordetella	1989
Effects of 5-HT1A receptor agonists and L-5-HTP in Montgomery's conflict test. Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:1 Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Conflict, Psychological; Male; Motor Activity; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1989
Effects of the putative anxiolytic SM-3997 on central monoaminergic systems. Pharmacology, biochemistry, and behavior, 1989, Volume: 32, Issue:4 Topics: Animals; Anti-Anxiety Agents; Biogenic Monoamines; Brain; Brain Chemistry; Buspirone; Dopamine; Imipramine; Isoindoles; Male; Norepinephrine; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Serotonin	1989
Prevention of the analgesic consequences of social defeat in male mice by 5-HT1A anxiolytics, buspirone, gepirone and ipsapirone. Psychopharmacology, 1989, Volume: 99, Issue:3 Topics: Analgesia; Animals; Anti-Anxiety Agents; Buspirone; Male; Mice; Mice, Inbred DBA; Nociceptors; Pindolol; Pyrimidines; Reaction Time; Social Behavior	1989
The effects of gepirone and 1-(2-pyrimidinyl)-piperazine on levels of corticosterone in rat plasma. Neuropharmacology, 1989, Volume: 28, Issue:4 Topics: Animals; Buspirone; Circadian Rhythm; Corticosterone; Dose-Response Relationship, Drug; Hypothalamo-Hypophyseal System; Male; Pituitary-Adrenal System; Pyrimidines; Rats; Rats, Inbred Strains; Stress, Physiological	1989
The effects of buspirone, BMY-13805 and 1-(2-pyrimidinyl)-piperazine on cat spinal reflexes. Methods and findings in experimental and clinical pharmacology, 1985, Volume: 7, Issue:5 Topics: Animals; Anti-Anxiety Agents; Buspirone; Cats; Female; Ganglia, Spinal; Male; Piperazines; Pyrimidines; Reflex; Reflex, Monosynaptic; Spinal Cord	1985
Disposition of the psychotropic drugs buspirone, MJ-13805 and piribedil, and of their common active metabolite 1-(2-pyrimidinyl)-piperazine in the rat. Xenobiotica; the fate of foreign compounds in biological systems, 1985, Volume: 15, Issue:10 Topics: Animals; Anti-Anxiety Agents; Blood Proteins; Brain; Buspirone; Kinetics; Male; Piperazines; Piribedil; Protein Binding; Pyrimidines; Rats; Rats, Inbred Strains	1985
Serotonergic mechanisms in the behavioral effects of buspirone and gepirone. Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3 Topics: 5,7-Dihydroxytryptamine; Animals; Anti-Anxiety Agents; Behavior, Animal; Biogenic Amines; Buspirone; Conflict, Psychological; Diazepam; Male; Pyrimidines; Rats; Rats, Inbred Strains; Reflex, Startle; Serotonin; Synaptic Transmission	1986
A study of the effects of buspirone, BMY 13805, and 1-PP on dopaminergic metabolism in the nucleus accumbens using in vivo voltammetry in freely moving rats. Life sciences, 1986, Aug-25, Volume: 39, Issue:8 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Buspirone; Dopamine; Electrochemistry; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Nucleus Accumbens; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Septal Nuclei	1986
Behavioral studies with anxiolytic drugs. III. Antipunishment actions of buspirone in the pigeon do not involve benzodiazepine receptor mechanisms. The Journal of pharmacology and experimental therapeutics, 1986, Volume: 238, Issue:3 Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Buspirone; Chlordiazepoxide; Columbidae; Diazepam; Flumazenil; Flunitrazepam; Punishment; Pyrimidines; Receptors, GABA-A	1986
[Effect of anxiolytics--buspirone and diazepam--on the prolactin, thyrotropin and cortisol content of the blood in the green monkey]. Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 102, Issue:12 Topics: Animals; Anti-Anxiety Agents; Buspirone; Chlorocebus aethiops; Diazepam; Hydrocortisone; Male; Prolactin; Pyrimidines; Thyrotropin; Time Factors	1986
Effects of 5-HT1A selective anxiolytics on lordosis behavior: interactions with progesterone. European journal of pharmacology, 1986, Dec-16, Volume: 132, Issue:2-3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Drug Interactions; Estrogens; Posture; Progesterone; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Sexual Behavior, Animal; Tetrahydronaphthalenes	1986
Pharmacological evidence for the involvement of 1-(2-pyridinyl)-piperazine (1-PmP) in the interaction of buspirone or gepirone with noradrenergic systems. European journal of pharmacology, 1987, Jan-28, Volume: 134, Issue:1 Topics: Animals; Anti-Anxiety Agents; Body Temperature; Buspirone; Clonidine; Male; Mice; Motor Activity; Oxidation-Reduction; Piperazines; Pyridines; Pyrimidines	1987
Novel anxiolytics discriminate between postsynaptic serotonin receptors mediating different physiological responses on single neurons of the rat hippocampus. Naunyn-Schmiedeberg's archives of pharmacology, 1987, Volume: 336, Issue:1 Topics: Animals; Anti-Anxiety Agents; Buspirone; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Neurons; Pyramidal Tracts; Pyrimidines; Rats; Receptors, Serotonin; Synapses; Tetrodotoxin	1987
Behavioral studies with anxiolytic drugs. IV. Serotonergic involvement in the effects of buspirone on punished behavior of pigeons. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 243, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Columbidae; Dose-Response Relationship, Drug; Ketanserin; Male; Punishment; Pyrazines; Pyrimidines; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes; Tritium	1987
Reversal of helpless behavior in rats by putative 5-HT1A agonists. Biological psychiatry, 1988, Feb-01, Volume: 23, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Avoidance Learning; Buspirone; Escape Reaction; Helplessness, Learned; Male; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1988
[Interaction of the anxiolytic agent buspirone with serotonin and other synaptic receptors in the human brain]. Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 105, Issue:1 Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Binding Sites; Brain; Buspirone; Cerebral Cortex; Female; Flunitrazepam; Hippocampus; Humans; Imipramine; In Vitro Techniques; Male; Middle Aged; Pyrimidines; Receptors, Neurotransmitter; Receptors, Serotonin; Strychnine; Tryptamines	1988
Effects of the novel anxiolytics gepirone, buspirone and ipsapirone on free feeding and on feeding induced by 8-OH-DPAT. Psychopharmacology, 1987, Volume: 93, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Eating; Hyperphagia; Male; Naphthalenes; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1987
Effects of housing and muricidal behavior on serotonergic receptors and interactions with novel anxiolytic drugs. Journal of neural transmission, 1988, Volume: 71, Issue:2 Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Appetitive Behavior; Brain; Buspirone; Male; Mice; Predatory Behavior; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Social Environment; Spiperone	1988
Anxiolytic effects of buspirone and gepirone in the fear-potentiated startle paradigm. Psychopharmacology, 1988, Volume: 94, Issue:1 Topics: Animals; Anti-Anxiety Agents; Buspirone; Dose-Response Relationship, Drug; Fear; Injections, Intraventricular; Injections, Spinal; Male; Pyrimidines; Rats; Rats, Inbred Strains; Reflex, Startle	1988
Activation of the 5-HT1A receptor subtype increases rat plasma ACTH concentration. European journal of pharmacology, 1988, Mar-15, Volume: 147, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Buspirone; Male; Physostigmine; Pindolol; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes	1988
5-Hydroxytryptamine1A receptor-mediated effects of buspirone, gepirone and ipsapirone. Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:4 Topics: Animals; Anti-Anxiety Agents; Buspirone; Corticosterone; Hypothermia, Induced; Male; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin	1988
Effects of buspirone differ from those of gepirone and 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) on unpunished responding of pigeons. Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Buspirone; Columbidae; Conditioning, Operant; Dose-Response Relationship, Drug; Male; Naphthalenes; Punishment; Pyrimidines; Tetrahydronaphthalenes	1988
The alpha 2-adrenoceptor antagonist activity of ipsapirone and gepirone is mediated by their common metabolite 1-(2-pyrimidinyl)-piperazine (PmP). European journal of pharmacology, 1988, Jul-14, Volume: 151, Issue:3 Topics: Administration, Oral; Adrenergic alpha-Antagonists; Animals; Anti-Anxiety Agents; Buspirone; Chromatography, High Pressure Liquid; Clonidine; Drug Interactions; Gastrointestinal Transit; Injections, Intravenous; Male; Pyrimidines; Rats	1988
Strychnine seizure potentiation by azaspirodecanedione anxiolytics in rats. European journal of pharmacology, 1988, Oct-18, Volume: 155, Issue:3 Topics: Animals; Anti-Anxiety Agents; Buspirone; Drug Synergism; Male; Olivary Nucleus; Pyridines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Seizures; Strychnine; Syndrome	1988
Relationship of increased food intake and plasma ACTH levels to 5-HT1A receptor activation in rats. Psychoneuroendocrinology, 1988, Volume: 13, Issue:6 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Animals; Anti-Anxiety Agents; Body Weight; Brain; Buspirone; Eating; Male; Naphthalenes; Pyrimidines; Rats; Receptors, Serotonin; Tetrahydronaphthalenes	1988
Simultaneous determination of buspirone, gepirone, ipsapirone and their common metabolite 1-(2-pyrimidinyl)piperazine in rat plasma and brain by high-performance liquid chromatography. Journal of chromatography, 1988, Oct-14, Volume: 431, Issue:2 Topics: Animals; Anti-Anxiety Agents; Brain Chemistry; Buspirone; Male; Pyrimidines; Rats; Spectrophotometry, Ultraviolet	1988
Monoaminergic involvement in the pharmacological actions of buspirone. British journal of pharmacology, 1985, Volume: 86, Issue:3 Topics: Animals; Apomorphine; Behavior, Animal; Brain; Buspirone; Dopamine; Ketanserin; Male; Methoxydimethyltryptamines; Monoamine Oxidase; p-Chloroamphetamine; Piperazines; Piperidines; Psychotropic Drugs; Pyrimidines; Rats; Serotonin	1985
Blockade of potentiated startle responding in rats by 5-hydroxytryptamine1A receptor ligands. European journal of pharmacology, 1988, Nov-08, Volume: 156, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Male; Methysergide; Naphthalenes; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Reflex, Startle; Tetrahydronaphthalenes	1988
Tissue-dependent alpha adrenoceptor activity of buspirone and related compounds. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:3 Topics: Animals; Buspirone; Cerebral Cortex; Clonidine; Guinea Pigs; Male; Norepinephrine; Phenylephrine; Prazosin; Pyrimidines; Rabbits; Rats; Receptors, Adrenergic, alpha; Vas Deferens	1987
'Taming' of wild rats (Rattus rattus) by 5HT1A agonists buspirone and gepirone. Pharmacology, biochemistry, and behavior, 1988, Volume: 31, Issue:2 Topics: Animals; Behavior, Animal; Buspirone; Dose-Response Relationship, Drug; Female; Male; Muridae; Pyrimidines; Rats; Receptors, Serotonin; Serotonin	1988
Discriminative stimulus properties of buspirone in the pigeon. The Journal of pharmacology and experimental therapeutics, 1987, Volume: 240, Issue:2 Topics: Animals; Apomorphine; Buspirone; Clozapine; Columbidae; Discrimination Learning; Haloperidol; Methysergide; Midazolam; Pyrimidines; Serotonin	1987
Comparative neuropharmacology of buspirone and MJ-13805, a potential anti-anxiety drug. Journal of neural transmission, 1983, Volume: 57, Issue:4 Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Anxiety Agents; Apomorphine; Buspirone; Catalepsy; Corpus Striatum; Dopamine; Female; Humans; Pyrimidines; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Synaptosomes; Tyrosine 3-Monooxygenase	1983
Anticonflict effects of acute and chronic treatments with buspirone and gepirone in rats. Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:3 Topics: Animals; Anti-Anxiety Agents; Buspirone; Conflict, Psychological; Male; Pyrimidines; Rats; Rats, Wistar; Serotonin Receptor Agonists; Time Factors	1995
Gepirone and 1-(2-pyrimidinyl)-piperazine-induced reduction of aversively evoked ultrasonic vocalisation in the rat. Pharmacology, biochemistry, and behavior, 1994, Volume: 48, Issue:1 Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Buspirone; Darkness; Electroshock; Light; Male; Motor Activity; Proadifen; Pyrimidines; Rats; Rats, Wistar; Ultrasonics; Vocalization, Animal	1994
The effects of azapirones on serotonin1A neurons of the dorsal raphe. General pharmacology, 1994, Volume: 25, Issue:4 Topics: Animals; Buspirone; Dose-Response Relationship, Drug; Isoindoles; Male; Piperazines; Pyrimidines; Raphe Nuclei; Rats; Receptors, Serotonin; Serotonin Receptor Agonists	1994
Tolerance development to the vagal-mediated bradycardia produced by 5-HT1A receptor agonists. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Cats; Drug Tolerance; Heart Rate; Indoles; Pyrimidines; Serotonin Receptor Agonists; Vagus Nerve	1994
Excitation of noradrenergic cell firing by 5-hydroxytryptamine1A agonists correlates with dopamine antagonist properties. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dopamine; Dopamine Antagonists; Haloperidol; Locus Coeruleus; Male; Neurons; Norepinephrine; Pyrimidines; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Receptor Agonists; Substantia Nigra	1994
Effect of 5-HT-1A receptor agonists on paw licking reaction on hot plate and unpunished drinking in rat. Life sciences, 1993, Volume: 52, Issue:12 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Drinking Behavior; Indoles; Male; Pain; Prosencephalon; Punishment; Pyrimidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Thirst; Time Factors	1993
Sleep and waking in 5,7-DHT-lesioned or (-)-pindolol-pretreated rats after administration of buspirone, ipsapirone, or gepirone. Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:2 Topics: 5,7-Dihydroxytryptamine; Adrenergic beta-Antagonists; Animals; Biogenic Monoamines; Brain Chemistry; Buspirone; Dose-Response Relationship, Drug; Male; Pindolol; Pyrimidines; Rats; Rats, Wistar; Serotonin Agents; Serotonin Receptor Agonists; Sleep; Sleep, REM; Wakefulness	1995
The anxiolytic serotonin 5-HT1A receptor agonists buspirone, ipsapirone and gepirone are inhibitors of tyrosine hydroxylation in rat striatum. Behavioural brain research, 1996, Volume: 73, Issue:1-2 Topics: Animals; Anti-Anxiety Agents; Buspirone; Dopamine Antagonists; Enzyme Inhibitors; Male; Neostriatum; Piperazines; Pyrimidines; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Serotonin Receptor Agonists; Sulpiride; Synaptosomes; Tyrosine 3-Monooxygenase	1996
5-HT1A agonists induce central cholinergic antinociception. Pharmacology, biochemistry, and behavior, 1997, Volume: 57, Issue:4 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; GTP-Binding Proteins; Male; Mice; Motor Activity; Pain; Pain Measurement; Pain Threshold; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists	1997
Modification of hypothalamic-pituitary-adrenocortical activity by serotonergic agents in the rat. Pharmacology, 1997, Volume: 55, Issue:2 Topics: Adrenal Cortex; Animals; Behavior, Animal; Buspirone; Carbolines; Corticosterone; Dose-Response Relationship, Drug; Isoindoles; Male; Piperazines; Pituitary Gland; Pyridines; Pyrimidines; Rats; Serotonin Receptor Agonists	1997
Characterization of rat exploratory behavior using the exploration box test. Methods and findings in experimental and clinical pharmacology, 1997, Volume: 19, Issue:10 Topics: Amphetamine; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; Buspirone; Carbolines; Diazepam; Dose-Response Relationship, Drug; Exploratory Behavior; Female; Male; Pyrimidines; Rats; Rats, Wistar	1997
Gepirone and 1-(2-pyrimidinyl)-piperazine in vitro: human cytochromes mediating transformation and cytochrome inhibitory effects. Psychopharmacology, 1998, Volume: 140, Issue:3 Topics: Antidepressive Agents; Biotransformation; Buspirone; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Ketoconazole; Microsomes, Liver; Pyrimidines	1998
Modification of sexual behavior of Long-Evans male rats by drugs acting on the 5-HT1A receptor. Brain research, 1999, Mar-13, Volume: 821, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain Chemistry; Buspirone; Copulation; Dopamine Antagonists; Dose-Response Relationship, Drug; Haloperidol; Male; Penile Erection; Penis; Piperazines; Pyrimidines; Rats; Rats, Long-Evans; Receptors, Dopamine D2; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Reflex; Serotonin; Serotonin Receptor Agonists; Spiperone	1999
Chronobiotic effects of gepirone, a potential antidepressant with 5HT1A receptor partial agonist properties. Behavioural pharmacology, 1999, Volume: 10, Issue:2 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents, Second-Generation; Buspirone; Circadian Rhythm; Cricetinae; Darkness; Light; Male; Mesocricetus; Motor Activity; Pyrimidines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists	1999
5-HT1A receptor agonists buspirone and gepirone attenuate apomorphine-induced aggressive behaviour in adult male Wistar rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2000, Volume: 51, Issue:4 Pt 2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aggression; Animals; Apomorphine; Behavior, Animal; Buspirone; Exploratory Behavior; Male; Motor Activity; Piperazines; Pyridines; Pyrimidines; Rats; Rats, Wistar; Serotonin Antagonists; Serotonin Receptor Agonists; Stereotyped Behavior	2000
Rigid analogues of buspirone and gepirone, 5-HT1A receptors partial agonists. Farmaco (Societa chimica italiana : 1989), 2002, Volume: 57, Issue:11 Topics: Binding, Competitive; Brain Chemistry; Buspirone; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Pyrimidines; Receptor, Serotonin, 5-HT2A; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Receptor Agonists; Spectrophotometry, Infrared	2002
Human cytochromes mediating gepirone biotransformation at low substrate concentrations. Biopharmaceutics & drug disposition, 2003, Volume: 24, Issue:2 Topics: Biotransformation; Buspirone; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Humans; In Vitro Techniques; Microsomes, Liver; Piperidones; Pyrimidines; Serotonin Receptor Agonists	2003
The 5-HT1A receptor and the stimulus effects of LSD in the rat. Psychopharmacology, 2005, Volume: 182, Issue:2 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Buspirone; Dose-Response Relationship, Drug; Lysergic Acid Diethylamide; Male; Piperazines; Pyridines; Pyrimidines; Rats; Rats, Inbred F344; Receptor, Serotonin, 5-HT1A; Serotonin 5-HT1 Receptor Agonists	2005