gentamicin and xanthenes

gentamicin has been researched along with xanthenes in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.23)18.2507
2000's10 (32.26)29.6817
2010's17 (54.84)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Leiser, J; Molitoris, BA; Sandoval, R1
Dunn, KW; Molitoris, BA; Sandoval, RM1
Bull, S; Klein, WR; Laffont, CM; van der Harst, MR1
Johnson, KC; Myrdal, SE; Steyger, PS1
Myrdal, SE; Steyger, PS1
Cotanche, DA; Dai, CF; Mangiardi, D; Steyger, PS1
Carey, JP; Chu, E; Della Santina, CC; Lyford-Pike, S; Vogelheim, C1
Dai, CF; Steyger, PS1
Flannery, JG; Gregory-Evans, CY; Gregory-Evans, K; Guerin, K; Hodges, MD; Mackay, DS; Moosajee, M1
Cohen, DM; Fu, Y; Karasawa, T; Steyger, PS; Wang, Q1
Steyger, PS; Wang, Q1
Kachelmeier, A; Steyger, PS; Wang, Q1
Dai, C; Steyger, PS; Yu, Y; Zhang, R; Zhang, Y1
Del Prado, G; Naves, P; Ponte, C; Soriano, F1
David, LL; Karasawa, T; Steyger, PS; Wang, Q1
Alharazneh, A; Cheng, AG; Huth, M; Luk, L; Monfared, A; Ricci, AJ; Steyger, PS1
Boger, ET; Friedman, TB; Frolenkov, GI; Indzhykulian, AA; Stepanyan, RS; Steyger, PS; VĂ©lez-Ortega, AC1
Li, H; Steyger, PS1
Luo, J; Xu, L1
Chu, YH; Escobedo, JO; Steyger, PS; Strongin, RM; Wang, Q1
Guan, BC; Jiang, M; Jiang, ZG; Karasawa, T; Ma, KT; Phillips, A; Steyger, PS; Wang, Q; Wang, T; Xie, DH; Yang, YQ1
Dai, CF; Steyger, PS; Zhang, R; Zhang, YB1
Chen, HC; Chen, HK; Chiang, MC; Li, SL; Liao, AH; Lin, YC; Shih, CP; Shih, YF; Sytwu, HK; Wang, CH1
Kim, HJ; Kim, SJ; Lee, JH; Oh, GS; Park, C; Park, R; Shen, A; So, HS1
Cho, HJ; Kim, MO; Lee, JH; Lee, KY; Park, S; Ryoo, Z; Yun, BW1
Ahmed, S; Banat, IM; Dunlop, P; Elshikh, M; Funston, S; Marchant, R; McGaw, M1
Ayoob, AM; Borenstein, JT; Langer, R; Peppi, M; Tandon, V1
Bai, H; Bing, J; Gao, X; Han, Z; Jiang, L; Wang, W; Wang, X; Xi, C; Xu, J; Zeng, S; Zhang, X1
Fujikawa, T; Griffith, AJ; Ito, T; Kawashima, Y; Kurima, K; Makabe, A; Maruyama, A; Sakamaki, Y; Tsutsumi, T1
Chen, D; Han, Y; Jiang, H; Jing, L; Li, R; Qian, X; Shao, W; Yin, Y; Zhong, D1
Chen, B; Chi, F; Dai, C; He, Z; Hetrick, A; Li, H; Qian, X; Ren, D; Wang, Y1

Other Studies

31 other study(ies) available for gentamicin and xanthenes

ArticleYear
Aminoglycoside antibiotics traffic to the Golgi complex in LLC-PK1 cells.
    Journal of the American Society of Nephrology : JASN, 1998, Volume: 9, Issue:2

    Topics: 3,3'-Diaminobenzidine; 4-Chloro-7-nitrobenzofurazan; Animals; Anti-Bacterial Agents; Ceramides; Endoplasmic Reticulum; Endosomes; Fluorescent Antibody Technique, Direct; Fluorescent Dyes; Gentamicins; Golgi Apparatus; LLC-PK1 Cells; Lysosomes; Methionine; Microscopy, Confocal; Microscopy, Electron; Proteins; Swine; Time Factors; Xanthenes

1998
Gentamicin traffics rapidly and directly to the Golgi complex in LLC-PK(1) cells.
    American journal of physiology. Renal physiology, 2000, Volume: 279, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Biological Transport; Epithelial Cells; Fluorescent Dyes; Gentamicins; Golgi Apparatus; Kidney; LLC-PK1 Cells; Swine; Xanthenes

2000
Gentamicin nephrotoxicity--a comparison of in vitro findings with in vivo experiments in equines.
    Veterinary research communications, 2005, Volume: 29, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Biomarkers; Cell Survival; Creatinine; Dogs; Dose-Response Relationship, Drug; Fluorescence Polarization Immunoassay; gamma-Glutamyltransferase; Gentamicins; Horses; Kidney Tubules, Distal; Kidney Tubules, Proximal; LLC-PK1 Cells; Male; Neutral Red; Oxazines; Reactive Oxygen Species; Swine; Xanthenes

2005
Cytoplasmic and intra-nuclear binding of gentamicin does not require endocytosis.
    Hearing research, 2005, Volume: 204, Issue:1-2

    Topics: Animals; Anti-Bacterial Agents; Binding Sites; Cell Line; Dogs; Dose-Response Relationship, Drug; Endocytosis; Fluorescent Dyes; Gentamicins; Immunohistochemistry; Kidney Tubules, Distal; Kidney Tubules, Proximal; Microscopy, Confocal; Neurons; Opossums; Phosphatidylinositol 4,5-Diphosphate; Xanthenes

2005
TRPV1 regulators mediate gentamicin penetration of cultured kidney cells.
    Hearing research, 2005, Volume: 204, Issue:1-2

    Topics: Anilides; Animals; Anti-Bacterial Agents; Arachidonic Acids; Calcium; Calcium Channel Blockers; Cell Line; Cinnamates; Diterpenes; Dogs; Endocannabinoids; Fluorescent Dyes; Gadolinium; Gentamicins; Hydrogen-Ion Concentration; Indicators and Reagents; Ionophores; Kidney Tubules, Distal; Lanthanum; Membrane Potentials; Polyunsaturated Alkamides; Ruthenium Red; TRPV Cation Channels; Valinomycin; Xanthenes

2005
Uptake of fluorescent gentamicin by vertebrate sensory cells in vivo.
    Hearing research, 2006, Volume: 213, Issue:1-2

    Topics: Animals; Anti-Bacterial Agents; Chickens; Fluorescent Dyes; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Rana catesbeiana; Time Factors; Xanthenes

2006
Gentamicin is primarily localized in vestibular type I hair cells after intratympanic administration.
    Journal of the Association for Research in Otolaryngology : JARO, 2007, Volume: 8, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Chinchilla; Gentamicins; Hair Cells, Vestibular; Humans; Immunohistochemistry; Tympanic Membrane; Xanthenes

2007
A systemic gentamicin pathway across the stria vascularis.
    Hearing research, 2008, Volume: 235, Issue:1-2

    Topics: Animals; Anti-Bacterial Agents; Blood-Brain Barrier; Dose-Response Relationship, Drug; Endolymph; Fluorescent Dyes; Gentamicins; Hair Cells, Auditory; Injections, Subcutaneous; Kidney; Mice; Mice, Inbred C57BL; Stria Vascularis; Xanthenes

2008
Systemic aminoglycoside treatment in rodent models of retinitis pigmentosa.
    Experimental eye research, 2008, Volume: 87, Issue:3

    Topics: Aminoglycosides; Animals; Carrier Proteins; cis-trans-Isomerases; Codon, Nonsense; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Electroretinography; Eye Proteins; Fluorescent Dyes; Gentamicins; Mice; Mice, Mutant Strains; Rats; Rats, Transgenic; Retina; Retinitis Pigmentosa; Rhodopsin; Xanthenes

2008
TRPV4 enhances the cellular uptake of aminoglycoside antibiotics.
    Journal of cell science, 2008, Sep-01, Volume: 121, Issue:Pt 17

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Calcium; Cell Line; Dogs; Ear, Inner; Endolymph; Extracellular Space; Gentamicins; Kidney; Methionine; Mice; Rats; TRPV Cation Channels; Xanthenes

2008
Trafficking of systemic fluorescent gentamicin into the cochlea and hair cells.
    Journal of the Association for Research in Otolaryngology : JARO, 2009, Volume: 10, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Cell Culture Techniques; Dogs; Dose-Response Relationship, Drug; Fluorescent Dyes; Gentamicins; Hair Cells, Auditory; Injections, Intraperitoneal; Mechanotransduction, Cellular; Mice; Mice, Inbred C57BL; Myosin VIIa; Myosins; Stria Vascularis; Xanthenes; Zebrafish

2009
Competitive antagonism of fluorescent gentamicin uptake in the cochlea.
    Hearing research, 2010, Sep-01, Volume: 268, Issue:1-2

    Topics: Aminoglycosides; Animals; Binding, Competitive; Biological Transport; Cell Line; Cochlea; Dose-Response Relationship, Drug; Fluorescent Dyes; Gentamicins; Injections, Intraperitoneal; Kanamycin; Kidney Tubules, Proximal; Kinetics; Mice; Mice, Inbred C57BL; Models, Biological; Stria Vascularis; Xanthenes

2010
Comparison of gentamicin distribution in the inner ear following administration via the endolymphatic sac or round window.
    The Laryngoscope, 2010, Volume: 120, Issue:10

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cochlea; Endolymphatic Sac; Evoked Potentials, Auditory, Brain Stem; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Meniere Disease; Microscopy, Confocal; Round Window, Ear; Xanthenes

2010
Differences in the in vitro susceptibility of planktonic and biofilm-associated Escherichia coli strains to antimicrobial agents.
    Journal of chemotherapy (Florence, Italy), 2010, Volume: 22, Issue:5

    Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Biofilms; Cefotaxime; Ciprofloxacin; Drug Resistance, Bacterial; Escherichia coli; Gentamicins; Humans; Microbial Sensitivity Tests; Oxazines; Plankton; Xanthenes

2010
CLIMP-63 is a gentamicin-binding protein that is involved in drug-induced cytotoxicity.
    Cell death & disease, 2010, Nov-18, Volume: 1

    Topics: 14-3-3 Proteins; Animals; Anti-Bacterial Agents; Cells, Cultured; Cochlea; Dimerization; Dithiothreitol; Endoplasmic Reticulum; Gentamicins; Humans; Kidney Tubules, Proximal; Lipoylation; Membrane Proteins; Mice; Protein Binding; RNA Interference; RNA, Small Interfering; Xanthenes

2010
Functional hair cell mechanotransducer channels are required for aminoglycoside ototoxicity.
    PloS one, 2011, Volume: 6, Issue:7

    Topics: Aminoglycosides; Animals; Cell Survival; Cells, Cultured; Cytoprotection; Endocytosis; Gentamicins; Hair Cells, Auditory; Imaging, Three-Dimensional; In Vitro Techniques; Ion Channel Gating; Ion Channels; Kinetics; Mechanotransduction, Cellular; Mice; Photons; Rats; Rats, Sprague-Dawley; Time Factors; Xanthenes

2011
TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells.
    Journal of the Association for Research in Otolaryngology : JARO, 2011, Volume: 12, Issue:6

    Topics: Aldehydes; Aminoglycosides; Animals; Cations; Chlorocebus aethiops; COS Cells; Cysteine Proteinase Inhibitors; Fluorescent Dyes; Genotype; Gentamicins; Hair Cells, Auditory, Outer; HEK293 Cells; Humans; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Culture Techniques; Oxidative Stress; Patch-Clamp Techniques; Pyridinium Compounds; Quaternary Ammonium Compounds; Transient Receptor Potential Channels; TRPA1 Cation Channel; Xanthenes

2011
Systemic aminoglycosides are trafficked via endolymph into cochlear hair cells.
    Scientific reports, 2011, Volume: 1

    Topics: Aminoglycosides; Animals; Biological Transport, Active; Endolymph; Female; Fluorescent Dyes; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Male; Models, Biological; Perilymph; Xanthenes

2011
Distribution of gentamicin in inner ear after local administration via a chitosan glycerophosphate hydrogel delivery system.
    The Annals of otology, rhinology, and laryngology, 2012, Volume: 121, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Ear, Inner; Fluorescent Dyes; Gentamicins; Hair Cells, Auditory; Hair Cells, Vestibular; Hydrogel, Polyethylene Glycol Dimethacrylate; Meniere Disease; Mice; Mice, Inbred C57BL; Xanthenes

2012
Live cell imaging of a fluorescent gentamicin conjugate.
    Natural product communications, 2012, Volume: 7, Issue:3

    Topics: Animals; Cell Line; Dogs; Fluorescent Dyes; Gentamicins; Protein Synthesis Inhibitors; Xanthenes

2012
Bumetanide hyperpolarizes madin-darby canine kidney cells and enhances cellular gentamicin uptake by elevating cytosolic Ca(2+) thus facilitating intermediate conductance Ca(2+)--activated potassium channels.
    Cell biochemistry and biophysics, 2013, Volume: 65, Issue:3

    Topics: Animals; Bumetanide; Calcium; Calcium Channel Blockers; Cell Polarity; Diuretics; Dogs; Gene Expression Regulation; Gentamicins; Kinetics; Madin Darby Canine Kidney Cells; Membrane Potentials; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Sodium-Potassium-Chloride Symporters; Sodium-Potassium-Exchanging ATPase; TRPV Cation Channels; Xanthenes

2013
Temporal and spatial distribution of gentamicin in the peripheral vestibular system after transtympanic administration in guinea pigs.
    Hearing research, 2013, Volume: 298

    Topics: Acoustic Maculae; Animals; Biological Transport; Epithelial Cells; Female; Fluorescent Dyes; Gentamicins; Guinea Pigs; Injections; Male; Microscopy, Confocal; Semicircular Ducts; Time Factors; Tissue Distribution; Tympanic Membrane; Vestibule, Labyrinth; Xanthenes

2013
Ultrasound-aided microbubbles facilitate the delivery of drugs to the inner ear via the round window membrane.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Apr-28, Volume: 167, Issue:2

    Topics: Acoustics; Animals; Biotin; Drug Delivery Systems; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Fluorescein-5-isothiocyanate; Gentamicins; Guinea Pigs; Microbubbles; Xanthenes

2013
Different uptake of gentamicin through TRPV1 and TRPV4 channels determines cochlear hair cell vulnerability.
    Experimental & molecular medicine, 2013, Mar-08, Volume: 45

    Topics: Animals; Cell Death; Cell Polarity; Cell Survival; Dose-Response Relationship, Drug; Gadolinium; Gentamicins; Hair Cells, Auditory; Hair Cells, Auditory, Inner; Rats; Rats, Sprague-Dawley; Ruthenium Red; Time Factors; TRPV Cation Channels; Xanthenes; Zebrafish

2013
tmie Is required for gentamicin uptake by the hair cells of mice.
    Comparative medicine, 2013, Volume: 63, Issue:2

    Topics: Animals; Behavior, Animal; Cochlea; Gentamicins; Hair Cells, Auditory; Mechanotransduction, Cellular; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Xanthenes

2013
Resazurin-based 96-well plate microdilution method for the determination of minimum inhibitory concentration of biosurfactants.
    Biotechnology letters, 2016, Volume: 38, Issue:6

    Topics: Anti-Bacterial Agents; Gentamicins; Indicators and Reagents; Microbial Sensitivity Tests; Oxazines; Reproducibility of Results; Streptococcus; Surface-Active Agents; Tetracycline; Xanthenes

2016
Intracochlear drug delivery: Fluorescent tracer evaluation for quantification of distribution in the cochlear partition.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2019, Jan-01, Volume: 126

    Topics: Animals; Cochlea; Dextrans; Drug Delivery Systems; Drug Liberation; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gentamicins; Guinea Pigs; Injections; Male; Optical Imaging; Perilymph; Pyridinium Compounds; Quaternary Ammonium Compounds; Tissue Distribution; Xanthenes

2019
Study of the Mechanisms by Which Aminoglycoside Damage Is Prevented in Chick Embryonic Hair Cells.
    Journal of the Association for Research in Otolaryngology : JARO, 2019, Volume: 20, Issue:1

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Chick Embryo; Gentamicins; Hair Cells, Auditory; Mechanotransduction, Cellular; Organ of Corti; Streptomycin; Xanthenes

2019
Systemic Fluorescent Gentamicin Enters Neonatal Mouse Hair Cells Predominantly Through Sensory Mechanoelectrical Transduction Channels.
    Journal of the Association for Research in Otolaryngology : JARO, 2020, Volume: 21, Issue:2

    Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Female; Gentamicins; Hair Cells, Auditory; Mechanotransduction, Cellular; Membrane Proteins; Mice; Mice, Transgenic; Xanthenes

2020
A new aminoglycoside etimicin shows low nephrotoxicity and ototoxicity in zebrafish embryos.
    Journal of applied toxicology : JAT, 2021, Volume: 41, Issue:7

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Embryo, Nonmammalian; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Hair Cells, Auditory; Kidney; Ototoxicity; Renal Insufficiency; Xanthenes; Zebrafish

2021
Hair cell uptake of gentamicin in the developing mouse utricle.
    Journal of cellular physiology, 2021, Volume: 236, Issue:7

    Topics: Animals; Biological Transport; Endocytosis; Female; Gentamicins; Hair Cells, Auditory; Male; Membrane Transport Modulators; Mice; Mice, Inbred C57BL; Organ Culture Techniques; Quinine; Reactive Oxygen Species; Saccule and Utricle; Staining and Labeling; Vestibular Diseases; Xanthenes

2021