gentamicin and lactic acid

gentamicin has been researched along with lactic acid in 60 studies

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (13.33)18.2507
2000's29 (48.33)29.6817
2010's19 (31.67)24.3611
2020's4 (6.67)2.80

Authors

AuthorsStudies
Brug, E; Meffert, R; Ritzerfeld, W; Teupe, C; Törmälä, P; Winckler, S1
Li, S; Mauduit, J; Vert, M1
Goosen, MF; Pichora, D; Wyss, UP; Zhang, X1
Hirano, K; Nagata, S; Takagishi, Y; Takeshima, K1
Arm, DM; Bohach, GA; Price, JS; Tencer, AF1
Frantz, A; Redbrake, C; Reim, M; Salla, S1
de Ruijter, JE; Jansen, JA; Matsuzaka, K; Walboomers, XF1
Ishii, Y; Sasaki, S1
Gamazo, C; Gander, B; Irache, JM; Merkle, HP; Prior, S1
Ragel, CV; Vallet-Regí, M1
Bozkurt, A; Erdem, A; Erdem, SR; Gündoğan, NU; Kara, A; Kilinç, K; Usubütün, A1
Blarer, N; Gamazo, C; Gander, B; Irache, JM; Merkle, HP; Prior, S; Subirá, ML1
Friess, W; Schlapp, M4
Blanco-Príeto, MJ; Gamazo, C; Kunkova, J; Lecaroz, C; Renedo, MJ1
Chan, EC; Liu, SJ; Ueng, SW; Wang, G1
Kakrdová, D; Kubícek, J; Kunes, P; Lonský, V; Mand'ák, J; Marsíková, M; Palicka, V; Zivný, P1
Gamazo, C; Gander, B; Irache, JM; Lecároz, C; Prior, S1
Cho, SH; Khang, G; Kim, JM; Kim, MS; Kim, YS; Lee, HB; Yoo, JY1
Shi, M; Xue, JM1
Fu, YC; Lee, DJ; Lew, MD; Naraharisetti, PK; Wang, CH1
Gamazo, C; Gander, B; Irache, JM; Prior, S1
Lukito, D; Tan, CH; Xue, JM1
Fu, YC; Guan Lee, HC; Lee, DJ; Naraharisetti, PK; Wang, CH1
Gbureck, U; Kissel, T; Schnieders, J; Thull, R1
Blanco-Prieto, MJ; Burrell, MA; Gamazo, C; Lecároz, C1
Elorza, B; Elorza, Mde L; Frutos, G; Torrado, S; Virto, MR1
Blanco-Prieto, MJ; Gamazo, C; Lecaroz, C; Renedo, MJ1
Blanco-Prieto, MJ; Campanero, MA; Gamazo, C; Lecaroz, MC; Salman, H1
Aviv, M; Berdicevsky, I; Zilberman, M1
Chen, H; Li, X; Shi, J; Wang, X; Zhang, L1
Gong, Y; Ren, L; Shi, X; Wang, DA; Wang, Y; Zhao, N1
Becker, E; Gelb, D; Ludwig, SC; Poelstra, KA; Stall, AC1
Huang, W; Ren, L; Shi, X; Wang, DA; Wang, Y1
He, Z; Kong, H; Xing, J; Xu, H1
Gosau, M; Müller, BW1
Blanco-Prieto, MJ; Elizondo, E; Gamazo, C; Imbuluzqueta, E; Moreno-Calvo, E; Veciana, J; Ventosa, N1
Chaisri, W; Ghassemi, AH; Hennink, WE; Okonogi, S1
Chen, DW; Chen, JK; Hsu, YH; Liao, JY; Liu, SJ; Ueng, SW1
Singh, D; Singh, MR1
Abdelghany, SM; Donnelly, RF; Gilmore, BF; Ingram, RJ; Quinn, DJ; Scott, CJ; Taggart, CC1
Delaney, P; Kavanagh, C; McManamon, C; Morris, MA; Rasappa, S; Wang, JJ1
Blanco-Prieto, MJ; Campanero, MÁ; Elizondo, E; Gamazo, C; Gil, AG; Imbuluzqueta, E; Lana, H; Salas, D; Veciana, J; Ventosa, N1
Ashraf, W; Bayston, R; Blunn, GW; Cox, HC; Goodship, AE; McLaren, JS; Quirk, RA; Rahman, CV; Scammell, BE; Shakesheff, KM; White, LJ1
Busscher, HJ; Dijkstra, RJ; Kavanagh, C; Neut, D; Thompson, JI; van der Mei, HC1
Jammalamadaka, U; Mills, DK; Nicholson, JC; Tappa, K; Weisman, JA; Wilson, CG1
Cross, GLW; de Silva, JP; Delaney, P; McManamon, C; Morris, MA1
Brzychczy-Włoch, M; Pamuła, E; Posadowska, U1
Brzychczy-Włoch, M; Chrzanowski, W; Dobrzyński, P; Drożdż, A; Krok-Borkowicz, M; Pamuła, E; Posadowska, U; Włodarczyk-Biegun, M1
Blanchemain, N; Chai, F; Degoutin, S; Ferri, J; Flores, C; Hornez, JC; Martel, B; Raoul, G; Siepmann, J1
Campardelli, R; Cricchio, V; Della Porta, G; Maffulli, N; Oliva, F; Reverchon, E1
Admane, P; Gupta, J; I J, A; Kumar, R; Panda, AK1
Das, G; Ramesh, A; Thiyagarajan, D1
Guo, W; Kuang, X; Liu, H; Sun, Y; Wang, Z; Zhou, S1
Chen, Y; Fu, X; Guo, S; Hu, G; Hwan Oh, D; Jin, Y; Ma, B; Zeng, Q1
Ben-Nissan, B; Bradbury, P; Chou, J; Karacan, I; Santos, J; Valenzuela, SM; Yiu, S1
Brzychczy-Włoch, M; Knap, K; Krok-Borkowicz, M; Kwiecień, K; Ochońska, D; Pamuła, E; Pudełko, I; Reczyńska-Kolman, K1
Anwar, J; Duran, S; Moin, ST1

Reviews

1 review(s) available for gentamicin and lactic acid

ArticleYear
Biodegradation of PLA/GA polymers: increasing complexity.
    Biomaterials, 1994, Volume: 15, Issue:15

    Topics: Biocompatible Materials; Biodegradation, Environmental; Chemistry, Pharmaceutical; Delayed-Action Preparations; Gentamicins; Lactates; Lactic Acid; Molecular Weight; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Stereoisomerism

1994

Other Studies

59 other study(ies) available for gentamicin and lactic acid

ArticleYear
Ciprofloxacin-impregnated poly-L-lactic acid drug carrier. New aspects of a resorbable drug delivery system in local antimicrobial treatment of bone infections.
    Archives of orthopaedic and trauma surgery, 1992, Volume: 112, Issue:1

    Topics: Biological Assay; Bone Diseases; Ciprofloxacin; Delayed-Action Preparations; Drug Delivery Systems; Gentamicins; Humans; Infections; Lactates; Lactic Acid; Methylmethacrylates; Polyesters; Polymers; Time Factors

1992
Biodegradable controlled antibiotic release devices for osteomyelitis: optimization of release properties.
    The Journal of pharmacy and pharmacology, 1994, Volume: 46, Issue:9

    Topics: Biocompatible Materials; Biodegradation, Environmental; Cefazolin; Delayed-Action Preparations; Gentamicins; Humans; Lactates; Lactic Acid; Osteomyelitis; Penicillin G; Polyesters; Polymers

1994
[Pharmaceutical dosage form design of copoly (lactic/glycolic acid) microspheres. Mechanism of in vitro release of gentamicin].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1994, Volume: 114, Issue:12

    Topics: Biotransformation; Delayed-Action Preparations; Drug Design; Gentamicins; Glycolates; Lactates; Lactic Acid; Microspheres; Molecular Weight; Polymers

1994
Controlled release of antibiotics from coated orthopedic implants.
    Journal of biomedical materials research, 1996, Volume: 30, Issue:3

    Topics: Anti-Bacterial Agents; Biocompatible Materials; Gentamicins; Kinetics; Lactic Acid; Microbial Sensitivity Tests; Orthopedic Fixation Devices; Osteomyelitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Prostheses and Implants; Staphylococcus aureus

1996
[Energy metabolism of the human cornea in various culture systems].
    Klinische Monatsblatter fur Augenheilkunde, 1997, Volume: 210, Issue:4

    Topics: Adenine Nucleotides; Blood Glucose; Cell Count; Chondroitin Sulfates; Complex Mixtures; Corneal Transplantation; Culture Media, Serum-Free; Dextrans; Endothelium, Corneal; Energy Metabolism; Gentamicins; Humans; Lactic Acid; Organ Preservation; Water-Electrolyte Balance

1997
The effect of poly-L-lactic acid with parallel surface micro groove on osteoblast-like cells in vitro.
    Biomaterials, 1999, Volume: 20, Issue:14

    Topics: Alkaline Phosphatase; Animals; Biocompatible Materials; Bone Marrow Cells; Calcification, Physiologic; Cells, Cultured; Extracellular Matrix; Gentamicins; Lactic Acid; Microscopy, Electron, Scanning; Osteoblasts; Polyesters; Polymers; Rats; Tetracycline

1999
Apatite cement containing antibiotics: efficacy in treating experimental osteomyelitis.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 1999, Volume: 4, Issue:5

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Apatites; Bone Cements; Bone Marrow; Bone Transplantation; Calcium Phosphates; Curettage; Delayed-Action Preparations; Disease Models, Animal; Disease Progression; Drug Delivery Systems; Female; Gentamicins; Lactic Acid; Osteogenesis; Osteomyelitis; Polyesters; Polymers; Rabbits; Staphylococcal Infections; Therapeutic Irrigation; Tibia

1999
Gentamicin encapsulation in PLA/PLGA microspheres in view of treating Brucella infections.
    International journal of pharmaceutics, 2000, Feb-25, Volume: 196, Issue:1

    Topics: Biocompatible Materials; Brucellosis; Drug Compounding; Gentamicins; Lactic Acid; Microbial Sensitivity Tests; Microspheres; Molecular Weight; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Staphylococcus aureus

2000
In vitro bioactivity and gentamicin release from glass-polymer-antibiotic composites.
    Journal of biomedical materials research, 2000, Sep-05, Volume: 51, Issue:3

    Topics: Apatites; Biocompatible Materials; Bone and Bones; Drug Delivery Systems; Drug Implants; Gentamicins; Glass; Humans; In Vitro Techniques; Lactic Acid; Microscopy, Electron, Scanning; Polyesters; Polymers; Polymethyl Methacrylate; Spectroscopy, Fourier Transform Infrared; X-Ray Diffraction

2000
The protective effect of taurine against gentamicin-induced acute tubular necrosis in rats.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2000, Volume: 15, Issue:8

    Topics: Acute Disease; Animals; Creatinine; Female; Gentamicins; Kidney; Kidney Tubular Necrosis, Acute; Lactic Acid; Lipid Peroxides; Male; Oxidoreductases; Polyuria; Rats; Rats, Wistar; Taurine; Thiobarbituric Acid Reactive Substances

2000
In vitro phagocytosis and monocyte-macrophage activation with poly(lactide) and poly(lactide-co-glycolide) microspheres.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2002, Volume: 15, Issue:2

    Topics: Aminoglycosides; Animals; Biocompatible Materials; Cells, Cultured; Drug Delivery Systems; Gentamicins; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Macrophage Activation; Macrophages; Mice; Microspheres; Monocytes; Phagocytosis; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Respiratory Burst; Static Electricity

2002
Release mechanisms from gentamicin loaded poly(lactic-co-glycolic acid) (PLGA) microparticles.
    Journal of pharmaceutical sciences, 2002, Volume: 91, Issue:3

    Topics: Anti-Bacterial Agents; Calorimetry, Differential Scanning; Gentamicins; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Spectroscopy, Fourier Transform Infrared; Thermodynamics

2002
Modifying the release of gentamicin from microparticles using a PLGA blend.
    Pharmaceutical development and technology, 2002, Volume: 7, Issue:2

    Topics: Gentamicins; Lactic Acid; Microspheres; Molecular Weight; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility

2002
In vitro evaluation of gentamicin released from microparticles.
    International journal of pharmaceutics, 2002, Aug-21, Volume: 242, Issue:1-2

    Topics: Anti-Bacterial Agents; Drug Carriers; Drug Compounding; Gentamicins; Kinetics; Lactic Acid; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solvents

2002
Collagen/PLGA microparticle composites for local controlled delivery of gentamicin.
    Journal of pharmaceutical sciences, 2003, Volume: 92, Issue:11

    Topics: Anti-Bacterial Agents; Centrifugation; Chemistry, Pharmaceutical; Collagen; Delayed-Action Preparations; Excipients; Freeze Drying; Freezing; Gentamicins; Hydrogen-Ion Concentration; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Molecular Weight; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Temperature

2003
The release of cefazolin and gentamicin from biodegradable PLA/PGA beads.
    International journal of pharmaceutics, 2004, Apr-01, Volume: 273, Issue:1-2

    Topics: Anti-Bacterial Agents; Biocompatible Materials; Cefazolin; Delayed-Action Preparations; Escherichia coli; Gentamicins; Kinetics; Lactic Acid; Microbial Sensitivity Tests; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Staphylococcus aureus

2004
Changes in metabolism and blood flow in peripheral tissue (skeletal muscle) during cardiac surgery with cardiopulmonary bypass: the biochemical microdialysis study.
    Perfusion, 2004, Volume: 19, Issue:1

    Topics: Aged; Aged, 80 and over; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Equipment Design; Extracellular Fluid; Female; Gentamicins; Humans; Hypothermia, Induced; Lactic Acid; Male; Microdialysis; Middle Aged; Muscle, Skeletal; Osmolar Concentration; Postoperative Period; Regional Blood Flow

2004
Gentamicin-loaded microspheres for reducing the intracellular Brucella abortus load in infected monocytes.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Brucella abortus; Brucellosis; Cell Line; Drug Compounding; Gentamicins; Lactic Acid; Mice; Microspheres; Monocytes; Particle Size; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Respiratory Burst

2004
Effect of lactide/glycolide monomers on release behaviors of gentamicin sulfate-loaded PLGA discs.
    International journal of pharmaceutics, 2004, May-19, Volume: 276, Issue:1-2

    Topics: Anti-Bacterial Agents; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Delivery Systems; Gentamicins; Hydrogen-Ion Concentration; Lactic Acid; Microbial Sensitivity Tests; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

2004
PLGA/mesoporous silica hybrid structure for controlled drug release.
    Journal of controlled release : official journal of the Controlled Release Society, 2004, Aug-11, Volume: 98, Issue:2

    Topics: Biological Availability; Delayed-Action Preparations; Drug Carriers; Gentamicins; Lactic Acid; Microscopy, Electron, Scanning; Microscopy, Electron, Transmission; Microscopy, Polarization; Microspheres; Molecular Weight; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Silanes; Silicon Dioxide

2004
Gentamicin-loaded discs and microspheres and their modifications: characterization and in vitro release.
    Journal of controlled release : official journal of the Controlled Release Society, 2005, Feb-02, Volume: 102, Issue:2

    Topics: Anti-Bacterial Agents; Chemistry, Pharmaceutical; Drug Compounding; Drug Delivery Systems; Excipients; Gentamicins; Lactic Acid; Methylcellulose; Microspheres; Molecular Weight; Particle Size; Pharmaceutic Aids; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Solubility; Surface Properties

2005
Gentamicin-loaded microspheres for treatment of experimental Brucella abortus infection in mice.
    The Journal of antimicrobial chemotherapy, 2005, Volume: 55, Issue:6

    Topics: Animals; Brucella abortus; Brucellosis; Female; Gentamicins; Lactic Acid; Mice; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

2005
Biodegradable polymer-silica xerogel composite microspheres for controlled release of gentamicin.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2006, Volume: 78, Issue:2

    Topics: Biocompatible Materials; Biodegradation, Environmental; Delayed-Action Preparations; Drug Stability; Gels; Gentamicins; Lactic Acid; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Silicon Dioxide

2006
Sterilization of gentamicin containing collagen/PLGA microparticle composites.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2006, Volume: 63, Issue:2

    Topics: Beta Particles; Calorimetry, Differential Scanning; Collagen; Electron Spin Resonance Spectroscopy; Gentamicins; Lactic Acid; Magnetic Resonance Spectroscopy; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Molecular Weight; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Temperature

2006
In vitro and in vivo release of gentamicin from biodegradable discs.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2006, Volume: 77, Issue:2

    Topics: Animals; Biodegradation, Environmental; Delayed-Action Preparations; Femur; Gentamicins; Kinetics; Lactic Acid; Osteomyelitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Rabbits

2006
Controlled release of gentamicin from calcium phosphate-poly(lactic acid-co-glycolic acid) composite bone cement.
    Biomaterials, 2006, Volume: 27, Issue:23

    Topics: Animals; Anti-Bacterial Agents; Bone Substitutes; Calcium Phosphates; Cell Line, Tumor; Drug Delivery Systems; Gentamicins; Lactic Acid; Mice; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

2006
Intracellular killing of Brucella melitensis in human macrophages with microsphere-encapsulated gentamicin.
    The Journal of antimicrobial chemotherapy, 2006, Volume: 58, Issue:3

    Topics: Anti-Bacterial Agents; Brucella melitensis; Cell Line; Drug Carriers; Gentamicins; Humans; Lactic Acid; Macrophages; Microspheres; Nanostructures; Particle Size; Phagocytosis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Respiratory Burst; Solubility

2006
Improvement of gentamicin poly(D,L-lactic-co-glycolic acid) microspheres for treatment of osteomyelitis induced by orthopedic procedures.
    Biomaterials, 2007, Volume: 28, Issue:5

    Topics: Antineoplastic Agents; Biocompatible Materials; Catalysis; Drug Delivery Systems; Gentamicins; Humans; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Models, Theoretical; Orthopedic Procedures; Osteomyelitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Sonication; X-Ray Diffraction

2007
Biodegradable micro- and nanoparticles as long-term delivery vehicles for gentamicin.
    Journal of microencapsulation, 2006, Volume: 23, Issue:7

    Topics: Agglutination Tests; Anti-Bacterial Agents; Biocompatible Materials; Calorimetry, Differential Scanning; Delayed-Action Preparations; Drug Compounding; Gentamicins; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Nanoparticles; Particle Size; Pharmaceutical Vehicles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Surface Properties; X-Ray Diffraction

2006
Poly(D,L-lactide-coglycolide) particles containing gentamicin: pharmacokinetics and pharmacodynamics in Brucella melitensis-infected mice.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Disease Models, Animal; Drug Carriers; Gentamicins; Lactic Acid; Mice; Mice, Inbred BALB C; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers

2007
Gentamicin-loaded bioresorbable films for prevention of bacterial infections associated with orthopedic implants.
    Journal of biomedical materials research. Part A, 2007, Volume: 83, Issue:1

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Biofilms; Colony Count, Microbial; Gentamicins; Glycolates; Lactic Acid; Microbial Sensitivity Tests; Microbial Viability; Molecular Weight; Orthopedic Equipment; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Prostheses and Implants; Prosthesis-Related Infections; Time Factors

2007
MBG/PLGA composite microspheres with prolonged drug release.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2009, Volume: 89, Issue:1

    Topics: Anti-Bacterial Agents; Biocompatible Materials; Drug Carriers; Gentamicins; Glass; Humans; Lactic Acid; Materials Testing; Microspheres; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2009
Novel mesoporous silica-based antibiotic releasing scaffold for bone repair.
    Acta biomaterialia, 2009, Volume: 5, Issue:5

    Topics: Animals; Body Fluids; Bone and Bones; Calcification, Physiologic; Calcium; Cell Death; Cell Proliferation; Drug Carriers; Durapatite; Gentamicins; Hydrogen-Ion Concentration; Lactic Acid; Mechanical Phenomena; Phosphates; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Porosity; Silicon Dioxide; Solutions; Surface Properties; Sus scrofa; Tissue Scaffolds; Wound Healing

2009
Reduction of postoperative spinal implant infection using gentamicin microspheres.
    Spine, 2009, Mar-01, Volume: 34, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Bone Nails; Delayed-Action Preparations; Drug Carriers; Female; Gentamicins; Hematoma; Lactic Acid; Laminectomy; Microspheres; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prosthesis-Related Infections; Rabbits; Spinal Fusion; Staphylococcal Infections; Surgical Wound Infection; Titanium

2009
A protein/antibiotic releasing poly(lactic-co-glycolic acid)/lecithin scaffold for bone repair applications.
    International journal of pharmaceutics, 2009, May-21, Volume: 373, Issue:1-2

    Topics: Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Biological Availability; Bone Regeneration; Calcification, Physiologic; Cell Differentiation; Cell Proliferation; Cell Survival; Delayed-Action Preparations; Drug Delivery Systems; Escherichia coli; Gentamicins; Hydrogen-Ion Concentration; Lactic Acid; Lecithins; Mesenchymal Stem Cells; Microscopy, Electron, Scanning; Osteoblasts; Osteogenesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Proteins; Rabbits; Serum Albumin, Bovine; Surface Properties; Tissue Scaffolds; Water

2009
[Optimization of preparation parameters for gentamicin-loaded PLLA nanoparticles and the drug release behavior in vitro].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2009, Volume: 26, Issue:2

    Topics: Delayed-Action Preparations; Drug Carriers; Gentamicins; Lactic Acid; Nanoparticles; Polyesters; Polymers

2009
Release of gentamicin sulphate from biodegradable PLGA-implants produced by hot melt extrusion.
    Die Pharmazie, 2010, Volume: 65, Issue:7

    Topics: Absorbable Implants; Anti-Bacterial Agents; Calorimetry, Differential Scanning; Chromatography, High Pressure Liquid; Drug Compounding; Excipients; Gentamicins; Lactic Acid; Microscopy, Electron, Scanning; Plasticizers; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Spectrophotometry, Ultraviolet; Water

2010
Novel bioactive hydrophobic gentamicin carriers for the treatment of intracellular bacterial infections.
    Acta biomaterialia, 2011, Volume: 7, Issue:4

    Topics: Anti-Infective Agents; Brucella melitensis; Brucellosis; Chemical Precipitation; Crystallization; Dioctyl Sulfosuccinic Acid; Drug Carriers; Gentamicins; Hydrophobic and Hydrophilic Interactions; Intracellular Space; Lactic Acid; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Solvents; Spectroscopy, Fourier Transform Infrared; Static Electricity; X-Ray Diffraction

2011
Enhanced gentamicin loading and release of PLGA and PLHMGA microspheres by varying the formulation parameters.
    Colloids and surfaces. B, Biointerfaces, 2011, Jun-01, Volume: 84, Issue:2

    Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Gentamicins; Lactic Acid; Microscopy, Electron, Scanning; Microspheres; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2011
Sustainable release of vancomycin, gentamicin and lidocaine from novel electrospun sandwich-structured PLGA/collagen nanofibrous membranes.
    International journal of pharmaceutics, 2012, Jul-01, Volume: 430, Issue:1-2

    Topics: Anesthetics, Local; Anti-Bacterial Agents; Cell Adhesion; Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; Child, Preschool; Chromatography, High Pressure Liquid; Collagen; Delayed-Action Preparations; Disk Diffusion Antimicrobial Tests; Drug Carriers; Drug Compounding; Drug Stability; Escherichia coli; Fibroblasts; Gentamicins; Humans; Infant; Kinetics; Lactic Acid; Lidocaine; Membranes, Artificial; Microbial Sensitivity Tests; Nanofibers; Nanotechnology; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Propanols; Solubility; Solvents; Staphylococcus aureus; Technology, Pharmaceutical; Vancomycin

2012
Development of antibiotic and debriding enzyme-loaded PLGA microspheres entrapped in PVA-gelatin hydrogel for complete wound management.
    Artificial cells, blood substitutes, and immobilization biotechnology, 2012, Volume: 40, Issue:5

    Topics: Animals; Biocompatible Materials; Debridement; Drug Combinations; Gelatin; Gentamicins; Guided Tissue Regeneration; Humans; Hydrogels; Lactic Acid; Mice; Microspheres; Muscle Contraction; Organ Culture Techniques; Peptide Hydrolases; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Re-Epithelialization; Tensile Strength; Wound Healing

2012
Gentamicin-loaded nanoparticles show improved antimicrobial effects towards Pseudomonas aeruginosa infection.
    International journal of nanomedicine, 2012, Volume: 7

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Colony Count, Microbial; Female; Gentamicins; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Mice; Microbial Sensitivity Tests; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pseudomonas aeruginosa; Pseudomonas Infections

2012
Depth profiling of PLGA copolymer in a novel biomedical bilayer using confocal Raman spectroscopy.
    Langmuir : the ACS journal of surfaces and colloids, 2013, May-14, Volume: 29, Issue:19

    Topics: Drug Delivery Systems; Gentamicins; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Spectrum Analysis, Raman

2013
Hydrophobic gentamicin-loaded nanoparticles are effective against Brucella melitensis infection in mice.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7

    Topics: Animals; Anti-Bacterial Agents; Brucella melitensis; Brucellosis; Cell Line; Drug Carriers; Female; Gentamicins; Humans; Hydrophobic and Hydrophilic Interactions; Lactic Acid; Macrophages; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2013
A biodegradable antibiotic-impregnated scaffold to prevent osteomyelitis in a contaminated in vivo bone defect model.
    European cells & materials, 2014, Jun-08, Volume: 27

    Topics: Animals; Anti-Infective Agents; Biodegradable Plastics; Bone Regeneration; Clindamycin; Femur; Gentamicins; Guided Tissue Regeneration; Lactic Acid; Osteomyelitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sheep; Staphylococcal Infections; Staphylococcus aureus; Tissue Scaffolds

2014
A biodegradable gentamicin-hydroxyapatite-coating for infection prophylaxis in cementless hip prostheses.
    European cells & materials, 2015, Jan-02, Volume: 29

    Topics: Animals; Anti-Bacterial Agents; Bone Cements; Bone Nails; Coated Materials, Biocompatible; Dogs; Drug Resistance, Bacterial; Durapatite; Female; Femur; Gentamicins; Hip Prosthesis; Lactic Acid; Male; Microscopy, Electron, Scanning; Osseointegration; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prosthesis-Related Infections; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis; Treatment Outcome

2015
Antibiotic and chemotherapeutic enhanced three-dimensional printer filaments and constructs for biomedical applications.
    International journal of nanomedicine, 2015, Volume: 10

    Topics: Anti-Bacterial Agents; Bacteria; Cell Line, Tumor; Cell Proliferation; Drug Delivery Systems; Gentamicins; Humans; Lactic Acid; Polyesters; Polymers; Printing, Three-Dimensional

2015
Characteristics, interactions and coating adherence of heterogeneous polymer/drug coatings for biomedical devices.
    Materials science & engineering. C, Materials for biological applications, 2016, Volume: 59

    Topics: Alloys; Coated Materials, Biocompatible; Gentamicins; Hip Prosthesis; Humans; Lactic Acid; Methicillin-Resistant Staphylococcus aureus; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Titanium

2016
Gentamicin loaded PLGA nanoparticles as local drug delivery system for the osteomyelitis treatment.
    Acta of bioengineering and biomechanics, 2015, Volume: 17, Issue:3

    Topics: Drug Delivery Systems; Drug Liberation; Gentamicins; Lactic Acid; Microbial Sensitivity Tests; Microscopy, Atomic Force; Nanoparticles; Osteomyelitis; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Solubility; Static Electricity

2015
Injectable hybrid delivery system composed of gellan gum, nanoparticles and gentamicin for the localized treatment of bone infections.
    Expert opinion on drug delivery, 2016, Volume: 13, Issue:5

    Topics: Anti-Bacterial Agents; Biocompatible Materials; Drug Carriers; Gentamicins; Humans; Injections, Intravenous; Lactic Acid; Microbial Sensitivity Tests; Nanoparticles; Osteomyelitis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polysaccharides, Bacterial; Staphylococcus aureus; Staphylococcus epidermidis

2016
Gentamicin-loaded poly(lactic-co-glycolic acid) microparticles for the prevention of maxillofacial and orthopedic implant infections.
    Materials science & engineering. C, Materials for biological applications, 2016, Jul-01, Volume: 64

    Topics: Biofilms; Coated Materials, Biocompatible; Gentamicins; Humans; Lactic Acid; Maxillofacial Prosthesis; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Staphylococcus aureus

2016
Injectable PLGA/Hydroxyapatite/Chitosan Microcapsules Produced by Supercritical Emulsion Extraction Technology: An In Vitro Study on Teriparatide/Gentamicin Controlled Release.
    Journal of pharmaceutical sciences, 2016, Volume: 105, Issue:7

    Topics: Bone Density Conservation Agents; Capsules; Chitosan; Chromatography, Supercritical Fluid; Delayed-Action Preparations; Durapatite; Emulsions; Excipients; Gentamicins; Kinetics; Lactic Acid; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protein Synthesis Inhibitors; Solubility; Teriparatide

2016
Design and evaluation of antibiotic releasing self- assembled scaffolds at room temperature using biodegradable polymer particles.
    International journal of pharmaceutics, 2017, Mar-30, Volume: 520, Issue:1-2

    Topics: Absorbable Implants; Animals; Biodegradable Plastics; Cell Survival; Cells, Cultured; Drug Implants; Drug Liberation; Fibroblasts; Gentamicins; Glycerol; Lactic Acid; Mice; Microbial Sensitivity Tests; Particle Size; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Temperature; Tissue Scaffolds

2017
Amphiphilic Cargo-Loaded Nanocarrier Enhances Antibiotic Uptake and Perturbs Efflux: Effective Synergy for Mitigation of Methicillin-Resistant Staphylococcus aureus.
    ChemMedChem, 2017, 07-20, Volume: 12, Issue:14

    Topics: Anti-Bacterial Agents; Biofilms; Cell Survival; Ciprofloxacin; Drug Carriers; Gentamicins; HEK293 Cells; Humans; Lactic Acid; Methicillin-Resistant Staphylococcus aureus; Nanocapsules; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer

2017
SS-31 peptide enables mitochondrial targeting drug delivery: a promising therapeutic alteration to prevent hair cell damage from aminoglycosides.
    Drug delivery, 2017, Volume: 24, Issue:1

    Topics: Aminoglycosides; Animals; Cell Death; Diterpenes; Drug Delivery Systems; Ear, Inner; Gentamicins; Hair Cells, Auditory; Hearing Loss; Lactic Acid; Lateral Line System; Membrane Potential, Mitochondrial; Mitochondria; Nanoparticles; Oligopeptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Protective Agents; Zebrafish

2017
Use of peptide-modified nanoparticles as a bacterial cell targeting agent for enhanced antibacterial activity and other biomedical applications.
    Food research international (Ottawa, Ont.), 2022, Volume: 161

    Topics: Anti-Bacterial Agents; Gentamicins; Humans; Lactic Acid; Nanoparticles; Peptides; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Staphylococcus aureus

2022
In vitro testing and efficacy of poly-lactic acid coating incorporating antibiotic loaded coralline bioceramic on Ti6Al4V implant against Staphylococcus aureus.
    Journal of tissue engineering and regenerative medicine, 2022, Volume: 16, Issue:12

    Topics: Anti-Bacterial Agents; Coated Materials, Biocompatible; Gentamicins; Humans; In Vitro Techniques; Lactic Acid; Polyesters; Staphylococcal Infections; Staphylococcus aureus

2022
Insight in Superiority of the Hydrophobized Gentamycin in Terms of Antibiotics Delivery to Bone Tissue.
    International journal of molecular sciences, 2022, Oct-11, Volume: 23, Issue:20

    Topics: Anti-Bacterial Agents; Bone and Bones; Dioctyl Sulfosuccinic Acid; Drug Carriers; Drug Delivery Systems; Gentamicins; Hydrogels; Lactic Acid; Nanoparticles; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Sodium

2022
Interaction of gentamicin and gentamicin-AOT with poly-(lactide-co-glycolate) in a drug delivery system - density functional theory calculations and molecular dynamics simulation.
    Biophysical chemistry, 2023, Volume: 294

    Topics: Anti-Bacterial Agents; Brucellosis; Density Functional Theory; Drug Delivery Systems; Gentamicins; Glycolates; Humans; Lactic Acid; Molecular Dynamics Simulation; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Surface-Active Agents

2023