gentamicin and isepamicin

gentamicin has been researched along with isepamicin in 157 studies

Research

Studies (157)

Timeframe	Studies, this research(%)	All Research%
pre-1990	37 (23.57)	18.7374
1990's	74 (47.13)	18.2507
2000's	33 (21.02)	29.6817
2010's	12 (7.64)	24.3611
2020's	1 (0.64)	2.80

Authors

Authors	Studies
Dinwiddie, CB; Isaacs, LL; Luft, FC; Rankin, LI; Sloan, RS; Yum, MN	1
Goering, RV; Sanders, CC; Sanders, WE	1
Kabins, SA; Nathan, C	1
Barrett, MS; Erwin, ME; Jones, RN; Koontz, FP	1
Hirose, T; Kumamoto, Y; Nishimura, M; Ohya, S; Shibuya, A; Tsukamoto, T	1
Affrime, MB; Awni, WM; Halstenson, CE; Heim-Duthoy, KL; Herman, CS; Keane, WF; Kelloway, JH; Teal, MA; Wong, MO	1
Caminero, MM; Fuentes Martinez, F; Izquierdo Izquierdo, J; Minguez Minguez, F; Prieto Prieto, J	1
Fujimoto, T; Kase, K; Shoshihara, M; Tsuda, Y; Yoshizawa, E	2
Inouye, S; Kettner, M; Miller, GH	1
Igarashi, K; Ikeda, S; Kashiwagi, K; Miyaji, A; Sasakawa, C; Tobe, T	1
Affrime, MB; Awni, WM; Halstenson, CE; Kelloway, JS; Lin, CC; Shapiro, BE; Teal, MA	1
Claes, J; De Broe, ME; Derde, MP; Govaerts, PJ; Kaufman, L; Marquet, JF; Van de Heyning, PH	1
Barrett, MS; Erwin, ME; Johnson, DM; Jones, RN	1
Kuzui, H; Murakami, T; Nishino, T; Obana, Y	1
Blaser, J	1
Feldman, S; Ravis, WR; Van, R; Walterspiel, JN	1
Eto, K; Ishii, T; Kumazawa, J; Matsumoto, T; Saito, Y; Sawae, Y; Ueda, S; Yushita, Y	1
Bamonte, F; Dionisotti, S; Ongini, E; Scaglione, F	1
Agra, M; Lurueña, S; Minguez, F; Prieto, J; Ramos, C	1
Baltch, AL; Ritz, WJ; Smith, RP; Valdes, JM	1
Fujimoto, T; Kase, K; Shoshihara, M; Takao, M; Yoshizawa, E	1
Kumagai, K; Nishibuchi, M; Otsuki, H; Takeda, Y	1
Horiba, M; Nagata, Y; Suzuki, K	1
Bagger-Sjöbäck, D; Harada, Y; Hirakawa, K; Nikaido, M; Nishida, I; Takumida, M	1
Awni, WM; Maloney, JA	1
Katsu, M; Saito, A	1
Hirao, H; Kamiryo, Y; Kato, M; Sanefuji, T	1
Hiraga, Y; Kobayashi, H; Nagahama, F; Nakabayashi, T; Nakayama, I; Onodera, S; Oshitani, H; Saito, A; Sasaki, N; Yoshida, M	1
Endo, K; Katsu, M; Kishi, H; Nakayama, I; Odagiri, S; Saito, A; Takebe, K; Tamura, T; Yoneda, M	1
Aoki, A; Gato, S; Saigusa, M; Shiritani, Y; Tsuji, A; Yamaji, S; Yokoiyama, S	1
Mizuno, A; Nakashima, M; Sato, R; Suzuki, Y; Uematsu, T; Yamazaki, T	1
Hayashi, M; Kinoshita, K; Morishita, M; Nakano, Y; Serizawa, K; Suzuki, T	1
Kobayashi, Y; Oyaide, K; Sono, A; Yamamoto, H	2
Hara, H; Hara, T; Iizuka, K; Matsumoto, K; Morino, T; Motoyama, K; Sano, K; Yamamoto, H	1
Endo, H; Matsumoto, K; Miura, M; Morino, T; Sano, K; Shiraiwa, K; Yamamoto, H	1
Iizuka, K; Matsumoto, K; Miura, M; Morino, T; Nakanishi, D; Sano, K; Yamamoto, H	1
Fujii, H; Matsumoto, K; Miura, M; Morino, T; Shiraiwa, K; Yamamoto, H	1
Kawaguchi, K; Kobayashi, Y; Sasaki, M; Yamada, H; Yamamoto, H	2
Kobayashi, Y; Kubota, H; Suda, M; Yamada, H; Yamamoto, H	1
Kobayashi, Y; Nakano, Y; Niimi, I; Yamamoto, H	1
Kobayashi, Y; Kohira, T; Yamamoto, H; Yano, J	1
Hokonohara, T; Mochizuki, D; Shinoda, Y; Takayanagi, N	1
Kinoshita, H; Mita, I; Nakano, U; Noguchi, M; Shibata, K; Shinoda, Y; Sohmiya, Y; Takayanagi, N; Uzawa, T	1
Endo, S; Morishita, M; Serizawa, K; Shirai, M; Somiya, Y; Suzuki, T	2
Iwasaki, M; Morishita, M; Sakai, A; Shirai, M; Somiya, Y; Suzuki, T	1
Endo, S; Morishita, M; Serizawa, K; Shirai, M; Suzuki, T	1
Endo, S; Morishita, M; Nakanishi, D; Sakai, A; Shirai, M; Somiya, Y; Suzuki, T	1
Iwasaki, M; Morishita, M; Muranishi, S; Serizawa, K; Suzuki, T; Takahashi, T	3
Norden, CW; Schafer, F	1
Bendirdjian, JP; Fillastre, JP; Foucher, B	1
Badal, RE; Baker, CN; Barry, AL; Jones, RN; Packer, RR; Thornsberry, C	1
Barry, AL; Gerlach, EH; Jones, RN; Thornsberry, C	1
Koga, H; Matsumoto, T	1
Chapuis, C; de Montclos, M; Flandrois, JP; Guinet, M	1
Goto, S; Kaneko, Y; Tsuji, A; Yamaguchi, K	1
Deguchi, K; Fukamoto, T; Fukayama, S; Ishihara, R; Koguchi, M; Nakane, Y; Oda, S; Suzuki, Y; Tanaka, S; Yokota, N	1
Godard, C; Hannecart-Pokorni, E; Hubrechts, JM; Maes, P; Nulens, E; Nyssen, HJ; Vanhoof, R; Wildemauwe, C	1
Carbon, C; Farinotti, R; Goldstein, F; Gutmann, L; Mainardi, JL; Mohler, J; Zhou, XY	1
Kobayashi, T; Nakano, S; Nishikawa, S; Ogawa, N; Ohdo, S; Shimada, H; Sugiyama, T; Tomonaga, F; Yoshiyama, Y	1
Kodama, Y; Kuranari, M; Nawata, T; Sakata, T; Sato, Y; Takeyama, M	1
Uematsu, T	1
Affrime, M; Cayen, M; Korduba, C; Lin, CC; Radwanski, E	1
Affrime, M; Batra, V; Cayen, MN; Cutler, D; Korduba, C; Lin, C; Nomeir, A; Radwanski, E	1
Blaise, D; Cordonnier, C; Espinouse, D; Herbrecht, R; Leblond, V; Minozzi, C; Sadoun, A; Sauvage, C	1
Colardyn, F	1
Covi, M; Velluti, G	1
Sturm, W	1
Esparza-Ahumada, S; Morfin-Otero, R; Rodriguez-Noriega, E	1
Giamarellou, H; Pefanis, A; Petrikkos, G; Tsagaraki, C	1
Beaucaire, G	1
Hare, RS; Miller, GH; Naples, L; Sabatelli, FJ; Shaw, KJ	1
Craig, WA	1
Affrime, MB; Barr, WH; Colucci, R; Cutler, D; Elliott, M; Lin, CC; Radwanski, E; Zampaglione, N	1
Affrime, M; Colucci, R; Cutler, D; Elliott, M; Guerciolini, R; Lin, CC; Radwanski, E; Scaglione, F; Viganò, A; Zampaglione, N	1
Jones, RN	1
Bamonte, F; Dionisotti, S; Fredelius, L; Ongini, E; Wersäll, J	1
Carbon, C	1
Blum, D	1
Principi, N; Viganò, A	1
Brasseur, R; Mingeot-Leclercq, MP; Schanck, A; Tulkens, PM; van Bambeke, F	1
Deguchi, K; Fukayama, S; Ishihara, R; Koguchi, M; Oda, S; Suzuki, Y; Tanaka, S	3
Cougnard, J; Minozzi, C; Padoin, C; Petitjean, O; Tod, M	1
Beauchamp, D; Bergeron, MG; Gourde, P; Grenier, L; Labrecque, G; Lin, L; Morin, NJ; Simard, M; Yoshiyama, Y	1
Carbon, C; Caulin, E; Collatz, E; Coutrot, A	1
Affrime, M; Batra, V; Cayen, M; Cutler, D; Korduba, C; Lin, CC; Nomeir, A; Radwanski, E	1
Abe, M; Imaoka, Y; Kamiyama, Y; Kunii, Y; Masamune, R; Momono, S; Oouchi, K; Toyoda, T; Toyoshima, T; Watanabe, I	1
Hilbert, MJ; Korduba, C; Lin, CC; Nomeir, A; Veals, J	1
Affrime, M; Batra, V; Cayen, MN; Christopher, D; Cutler, D; Korduba, C; Lin, CC; Nomeir, AA; Radwanski, E	1
DiGiammarino, EL; Draker, KA; Serpersu, EH; Wright, GD	1
Fuentes, F; Gomez-Lus, ML; Izquierdo, J; Martín, MM; Prieto, J	1
Izard, D; Vachée, A; Vincent, P	1
Iida, H; Kawanabe, K; Matsusue, Y; Nakamura, T; Okada, Y	1
Beauchamp, D; Kanke, M; Yazaki, T; Yoshiyama, Y	1
da Costa, SO; Igarashi, A; Igarashi, K; Kashiwagi, K; Saisho, T; Sakata, K; Tsuhako, MH	1
Aoki, T; Itoh, Y; Itokazu, M; Nishimoto, Y; Nonomura, H	1
Chung, CW; Jun, JH; Kim, KS; Lee, KH; Shim, JC	1
Sato, S; Toriya, M; Tsuji, A; Yamaguchi, S	1
Beaucaire, G; Cougnard, J; Minozzi, C; Petitjean, O; Ponsonnet, D; Tod, M	1
Allaouchiche, B; Boulétreau, P; Breilh, D; Chassard, D; Ducint, D; Jaumain, H; Malbec, I; Saux, MC	1
Endo, K	1
Cumps, J; El Mouedden, M; Laurent, G; Mingeot-Leclercq, MP; Taper, HS; Tulkens, PM	1
Hosino, K; Iwai, Y; Nakamura, A; Nakamura, S; O'Hara, K; Sawai, T; Seto, I	1
Bartsokas, C; Delis, D; Kafetzis, DA; Maltezou, HC; Mavrikou, M; Paraskakis, I; Siafas, C	1
Padoin, C; Petitjean, O; Tod, M	1
Minami, S; Ogake, N; Takahata, M; Yamashiro, Y	1
DeFillipo, K; Reif, V; Vogel, R	1
Hamada, K; Midorikawa, K; Naito, M; Shibata, Y; Yatsunami, M	1
Adinolfi, LE; Andreana, A; Ragone, E; Sarnataro, G; Tripodi, MF; Utili, R	1
DiGiammarino, EL; Ekman, DR; Serpersu, EH; Witter, ED; Wright, E	1
Coulaud, JM; Fauvelle, F; Lecointre, K; Poussel, JF; Tardy, D; Trape, G	1
Chen, YS; Lee, SS; Lin, HH; Lin, WR; Liu, YC; Tsai, TH; Wann, SR; Yen, MY	1
Hashimoto, Y; Kato, M; Liu, M	1
Baka, M; Gombakis, N; Kafetzis, DA; Koliouskas, DE; Kosmidou, H; Malaka-Zafiriou, E; Maltezou, HC	1
Minami, S; Takahata, M; Yamada, H	1
Beauchamp, D; Kanke, M; Wong, P; Yazaki, T; Yoshiyama, Y	1
Allaouchiche, B; Bel, JC; Boselli, E; Breilh, D; Chassard, D; Debon, R; Saux, MC	1
Iyobe, S; Okubo, T	1
Fukushige, T; Kano, T; Sano, T; Ueda, S; Yamada, S	1
Arashima, Y; Kato, K; Kono, K; Ogawa, M; Saito, T; Takeda, S; Watanabe, K	1
Aguiari, G; Banzi, M; Borea, PA; Cai, Y; Del Senno, L; Ferrari, L; Gessi, S; Harris, PC; Lambertini, E; Lanza, F; Manzati, E; Peters, DJ; Piva, R; Somlo, S; Zeggio, E	1
Barinov, SM; Hasegawa, M; Komlev, VS; Sudo, A; Uchida, A	1
Reshed'ko, GK	1
Ha, JS; Jeon, DS; Kim, HC; Kim, JR; Ryoo, NH	1
Avlamis, A; Florentin, I; Giamarellou, H; Grammatikou, M; Pephanis, A; Petrikkos, G	1
Gala, JL; Leal, T; Vandercam, B; Wallemacq, P; Yombi, JC	1
Cheng, NC; Hsueh, PR; Huang, WK; Liu, CY; Liu, YC; Shyr, JM; Teng, LJ	1
Moldavan, IA; Ryzhko, IV; Shcherbaniuk, AI; Smorodinova, IuV	1
Chen, JH; Shen, GH; Wu, BD; Wu, KM	1
Falagas, ME; Kopterides, P	1
Chang, SC; Feng, NH; Hsueh, PR; Tsai, TY; Wang, JT	1
Guo, ZL; He, LX; He, ZG; Liang, YJ; Ren, T; Zhai, XB; Zhang, L; Zheng, YH	1
Denamur, S; Mingeot-Leclercq, MP; Tulkens, PM; Van Bambeke, F	1
Fujita, Y; Horiuchi, R; Hosokawa, S; Nakamura, K; Yamamoto, K	1
Arakawa, S; Fujisawa, M; Shigemura, K; Yamashita, M; Yasufuku, T	1
Chow, JW; Frase, H; Smith, C; Toth, M; Vakulenko, SB	1
Gopal, R; Hahm, JS; Hahm, KS; Jeong, N; Kim, JY; Lee, JK; Park, SC; Park, Y; Son, BK; Yoo, S	1
Bali, R; Das, BK; Kapil, A	1
Cho, B; Im, SA; Park, GS; Yun, DY	1
Falagas, ME; Georgantzi, GG; Karageorgopoulos, DE; Rafailidis, PI; Sun, C; Wang, R	1
Falagas, ME; Karageorgopoulos, DE; Kofteridis, D; Maraki, S; Mavros, MN; Samonis, G	1
Fukunaga, K; Ikeuchi, M; Izumi, M; Kamimoto, Y; Sugimura, N; Takemura, M; Tani, T; Yokoyama, M	1
Falagas, ME; Georgantzi, GG; Kofteridis, DP; Maraki, S; Samonis, G; Vouloumanou, EK	1
Aso, K; Fukunaga, K; Ikeuchi, M; Izumi, M; Kamimoto, Y; Sugimura, N; Tani, T; Yokoyama, M	1
Chang, SC; Ho, MW; Hseuh, PR; Lee, CH; Liu, JW; Liu, JY; Sheng, WH; Wang, FD; Wang, JT	1
Chen, HC; Huang, CC; Huang, WC; Wu, MF	1
Ban, YH; Cha, SS; Hong, SK; Hwang, JY; Kim, HJ; Lee, NJ; Liu, HW; Park, JW; Shin, HL; Song, MC; Yoon, YJ	1
Aoyama, S; Izumi, K; Miyagi, T; Mizokami, A; Nakagawa, R; Nakashima, T; Ofude, M; Shigehara, K; Urata, S	1
Ali, HB; Asuman, B; Kubra, HU; Sarah, AF; Sreylis, N; Yeliz, TC	1

Reviews

8 review(s) available for gentamicin and isepamicin

Article	Year
[New antimicrobial agents series XXXIV: isepamicin]. The Japanese journal of antibiotics, 1989, Volume: 42, Issue:3 Topics: Bacteria; Bacterial Infections; Clinical Trials as Topic; Drug Resistance, Microbial; Gentamicins; Humans; Tissue Distribution	1989
Once-daily versus multiple-daily dosing of aminoglycosides. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Animals; Anti-Bacterial Agents; Drug Administration Schedule; Gentamicins; Humans	1995
Pharmacokinetics of isepamicin. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carbohydrate Sequence; Child; Child, Preschool; Gentamicins; Humans; Infant; Infant, Newborn; Middle Aged; Molecular Sequence Data	1995
Isepamicin (SCH 21420, 1-N-HAPA gentamicin B): microbiological characteristics including antimicrobial potency of spectrum of activity. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Anti-Bacterial Agents; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests	1995
An overview of the safety of isepamicin in adults. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Adult; Aged; Anti-Bacterial Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Creatinine; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Gentamicins; Hearing Disorders; Humans; Kidney Diseases; Liver; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic	1995
Clinical pharmacokinetics and pharmacodynamics of isepamicin. Clinical pharmacokinetics, 2000, Volume: 38, Issue:3 Topics: Adult; Aging; Animals; Anti-Bacterial Agents; Child; Gentamicins; Humans; Infant, Newborn; Injections, Intramuscular; Injections, Intravenous; Microbial Sensitivity Tests; Tissue Distribution	2000
Old antibiotics for infections in critically ill patients. Current opinion in critical care, 2007, Volume: 13, Issue:5 Topics: Anti-Bacterial Agents; Chloramphenicol; Critical Illness; Cross Infection; Drug Resistance, Bacterial; Drug Utilization; Fosfomycin; Fusidic Acid; Gentamicins; Humans; Polymyxins	2007
Susceptibility of Gram-negative bacteria to isepamicin: a systematic review. Expert review of anti-infective therapy, 2012, Volume: 10, Issue:2 Topics: Adult; Amikacin; Anti-Bacterial Agents; Child; Child, Preschool; Databases, Bibliographic; Drug Administration Schedule; Drug Resistance, Bacterial; Gentamicins; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Infant; Microbial Sensitivity Tests	2012

Trials

26 trial(s) available for gentamicin and isepamicin

Article	Year
Effect of concomitant administration of piperacillin on the dispositions of isepamicin and gentamicin in patients with end-stage renal disease. Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:9 Topics: Adult; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic; Piperacillin	1992
Treatment of complicated urinary tract infections with ofloxacin following an aminoglycoside. Chemotherapy, 1991, Volume: 37 Suppl 1 Topics: Administration, Oral; Adolescent; Aged; Bacteriuria; Drug Therapy, Combination; Gentamicins; Humans; Injections, Intramuscular; Male; Middle Aged; Ofloxacin; Recurrence; Remission Induction; Urinary Tract Infections	1991
[New antimicrobial agents series XXXIV: isepamicin]. The Japanese journal of antibiotics, 1989, Volume: 42, Issue:3 Topics: Bacteria; Bacterial Infections; Clinical Trials as Topic; Drug Resistance, Microbial; Gentamicins; Humans; Tissue Distribution	1989
[Clinical trial of HAPA-B in complicated urinary tract infections]. Hinyokika kiyo. Acta urologica Japonica, 1986, Volume: 32, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Drug Resistance, Microbial; Enterococcus faecalis; Escherichia coli; Female; Gentamicins; Humans; Male; Middle Aged; Pseudomonas aeruginosa; Serratia marcescens; Urinary Tract Infections	1986
Pharmacokinetics of intravenously administered isepamicin in men. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:12 Topics: Adult; Chromatography, High Pressure Liquid; Electrocardiography; Gentamicins; Half-Life; Humans; Infusions, Intravenous; Male	1995
Isepamicin once daily plus ceftriaxone versus amikacin plus ceftriaxone in febrile neutropenic patients. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Bone Marrow Transplantation; Ceftriaxone; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Gentamicins; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Neoplasms; Neutropenia; Superinfection	1995
The efficacy and safety of isepamicin and ceftazidime compared with amikacin and ceftazidime in acute lower respiratory tract infection. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Acute Disease; Amikacin; Anti-Bacterial Agents; Bronchitis; Ceftazidime; Cross Infection; Drug Administration Schedule; Drug Therapy, Combination; Female; Gentamicins; Gram-Negative Bacterial Infections; Humans; Male; Middle Aged; Pneumonia, Bacterial; Respiratory Tract Infections; Retrospective Studies	1995
Comparison of the efficacy and safety of isepamicin and amikacin in the treatment of acute lower respiratory tract infections caused by gram-negative organisms. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Bronchitis; Drug Administration Schedule; Drug Therapy, Combination; Female; Gentamicins; Gram-Negative Bacterial Infections; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Pneumonia, Bacterial; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections	1995
Isepamicin versus amikacin in the treatment of urinary tract infection. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Escherichia coli Infections; Female; Follow-Up Studies; Gentamicins; Humans; Male; Middle Aged; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Urinary Tract Infections	1995
Comparison of the efficacy and safety of isepamicin and amikacin in the treatment of skin and skin structure infections. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Drug Administration Schedule; Escherichia coli Infections; Female; Gentamicins; Gram-Negative Bacterial Infections; Humans; Male; Middle Aged; Proteus Infections; Proteus mirabilis; Pseudomonas aeruginosa; Pseudomonas Infections; Skin Diseases, Bacterial; Staphylococcal Skin Infections; Staphylococcus aureus	1995
Evaluation of the efficacy and safety of isepamicin in the treatment of various bacterial infections. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Drug Administration Schedule; Female; Genital Diseases, Female; Gentamicins; Humans; Male; Middle Aged; Respiratory Tract Infections; Skin Diseases, Bacterial; Urinary Tract Infections	1995
Evaluation of the efficacy and safety of isepamicin compared with amikacin in the treatment of nosocomial pneumonia and septicaemia. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Amikacin; Anti-Bacterial Agents; Bacteremia; Cross Infection; Drug Therapy, Combination; Female; Gentamicins; Gram-Negative Bacterial Infections; Humans; Lactams; Male; Middle Aged; Pneumonia, Bacterial; Prospective Studies	1995
Overview of the efficacy of isepamicin in the adult core clinical trial programme. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Abdomen; Adult; Aged; Amikacin; Anti-Bacterial Agents; Bacteremia; Drug Administration Schedule; Female; Gentamicins; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Male; Middle Aged; Prospective Studies; Respiratory Tract Infections; Skin Diseases, Bacterial; Urinary Tract Infections	1995
An overview of the safety of isepamicin in adults. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Adult; Aged; Anti-Bacterial Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Creatinine; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Gentamicins; Hearing Disorders; Humans; Kidney Diseases; Liver; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic	1995
A randomised comparison of isepamicin and amikacin in the treatment of bacterial infections in paediatric patients. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Drug Administration Schedule; Enterococcus faecalis; Escherichia coli Infections; Female; Gentamicins; Humans; Infant; Infant, Newborn; Klebsiella Infections; Klebsiella pneumoniae; Male; Staphylococcal Infections; Staphylococcus epidermidis; Streptococcal Infections	1995
Pharmacokinetics of isepamicin following a single administration by intravenous infusion or intramuscular injections. Antimicrobial agents and chemotherapy, 1997, Volume: 41, Issue:8 Topics: Adult; Anti-Bacterial Agents; Cross-Over Studies; Gentamicins; Humans; Infusions, Intravenous; Injections, Intramuscular; Male	1997
[Combination use of second generation cephem and isepamicin for the treatment of post-surgical infection of the lower digestive tract]. The Japanese journal of antibiotics, 1997, Volume: 50, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefmetazole; Cefotiam; Cefuroxime; Cephalosporins; Drug Therapy, Combination; Female; Gentamicins; Humans; Intestinal Diseases; Intestines; Male; Middle Aged; Peritonitis; Postoperative Complications; Surgical Wound Infection	1997
Isepamicin in intensive care unit patients with nosocomial pneumonia: population pharmacokinetic-pharmacodynamic study. The Journal of antimicrobial chemotherapy, 1999, Volume: 44, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bayes Theorem; Creatinine; Cross Infection; Dose-Response Relationship, Drug; Female; Gentamicins; Humans; Intensive Care Units; Kidney; Male; Middle Aged; Models, Biological; Pneumonia, Bacterial; Treatment Outcome	1999
Pharmacokinetics of isepamicin during continuous venovenous hemodiafiltration. Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:10 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bayes Theorem; Female; Gentamicins; Hemodiafiltration; Humans; Male; Metabolic Clearance Rate; Middle Aged	1999
Isepamicin versus amikacin for the treatment of acute pyelonephritis in children. International journal of antimicrobial agents, 2000, Volume: 14, Issue:1 Topics: Amikacin; Anti-Bacterial Agents; Child; Child, Preschool; Escherichia coli; Escherichia coli Infections; Female; Gentamicins; Humans; Infant; Infant, Newborn; Male; Pyelonephritis; Treatment Outcome; Urine	2000
Comparison of two methods to obtain a desired first isepamicin peak in intensive care patients. Fundamental & clinical pharmacology, 2001, Volume: 15, Issue:2 Topics: Acute Disease; Adult; Aged; Anti-Bacterial Agents; Bayes Theorem; Creatinine; Critical Care; Female; Gentamicins; Humans; Infusions, Intravenous; Intensive Care Units; Linear Models; Male; Metabolic Clearance Rate; Middle Aged; Respiration, Artificial; Treatment Outcome	2001
Once daily isepamicin treatment in complicated urinary tract infections. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 1999, Volume: 32, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Drug Administration Schedule; Female; Gentamicins; Humans; Male; Middle Aged; Prospective Studies; Urinary Tract Infections	1999
Comparison of isepamicin with amikacin for the empirical treatment of febrile neutropenic children with malignancies. International journal of antimicrobial agents, 2001, Volume: 18, Issue:4 Topics: Amikacin; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Drug-Related Side Effects and Adverse Reactions; Fever; Gentamicins; Humans; Male; Neoplasms; Neutropenia; Random Allocation	2001
Key pharmacokinetic parameters of isepamicin in febrile neutropenic cancer patients and in women with acute pelvic inflammatory disease. Journal of chemotherapy (Florence, Italy), 2005, Volume: 17, Issue:5 Topics: Acute Disease; Adult; Anti-Bacterial Agents; Area Under Curve; Female; Fever; Gentamicins; Hematologic Neoplasms; Humans; Infusions, Intravenous; Middle Aged; Neutropenia; Pelvic Inflammatory Disease	2005
Local infusion analgesia using intra-articular double lumen catheter after total knee arthroplasty: a double blinded randomized control study. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2013, Volume: 21, Issue:12 Topics: Aged; Amides; Analgesics; Anesthetics, Local; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; C-Reactive Protein; Catheterization; Dexamethasone; Double-Blind Method; Female; Gentamicins; Glucocorticoids; Humans; Infusions, Intraosseous; Male; Middle Aged; Osteoarthritis, Knee; Pain Management; Pain Measurement; Pain, Postoperative; Ropivacaine; Treatment Outcome	2013
Effects of dexamethasone on local infiltration analgesia in total knee arthroplasty: a randomized controlled trial. Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2014, Volume: 22, Issue:7 Topics: Aged; Amides; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents; Arthroplasty, Replacement, Knee; C-Reactive Protein; Dexamethasone; Female; Gentamicins; Humans; Injections, Intra-Articular; Interleukin-6; Male; Osteoarthritis, Knee; Pain Management; Pain Measurement; Pain, Postoperative; Ropivacaine; Treatment Outcome	2014

Other Studies

125 other study(ies) available for gentamicin and isepamicin

Article	Year
Comparative nephrotoxicity of SCH 21420 and amikacin in rats. Antimicrobial agents and chemotherapy, 1979, Volume: 16, Issue:4 Topics: Amikacin; Animals; Creatinine; Enzymes; Gentamicins; Kanamycin; Kidney Diseases; Male; Proteinuria; Rats; Time Factors	1979
In vitro studies with Sch 21420 and Sch 22591: activity in comparison with six other aminoglycosides and synergy with penicillin against enterococci. Antimicrobial agents and chemotherapy, 1978, Volume: 14, Issue:2 Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Synergism; Enterobacteriaceae; Gentamicins; Microbial Sensitivity Tests; Penicillin G; Sisomicin	1978
In vitro activity of Sch 21420, derivative of gentamicin B, compared to that of amikacin. Antimicrobial agents and chemotherapy, 1978, Volume: 14, Issue:5 Topics: Acetyltransferases; Amikacin; Aminoglycosides; Bacteria; Drug Resistance, Microbial; Gentamicins; Kanamycin; Microbial Sensitivity Tests	1978
CI-960 (PD127391 or AM-1091), sparfloxacin, WIN 57273, and isepamicin activity against clinical isolates of Mycobacterium avium-intracellularae complex, M. chelonae, and M. fortuitum. Diagnostic microbiology and infectious disease, 1992, Volume: 15, Issue:2 Topics: Anti-Bacterial Agents; Fluoroquinolones; Gentamicins; Humans; Microbial Sensitivity Tests; Mycobacterium avium Complex; Mycobacterium chelonae; Nontuberculous Mycobacteria; Quinolones	1992
[Significance of the combined treatment with isepamicin and piperacillin in an in vitro model for complicated cystitis operated by automatic simulator apparatus for urinary concentration]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1992, Volume: 66, Issue:1 Topics: Computer Simulation; Cystitis; Drug Therapy, Combination; Gentamicins; In Vitro Techniques; Piperacillin	1992
In vivo postantibiotic effect of isepamicin and other aminoglycosides in a thigh infection model in neutropenic mice. Chemotherapy, 1992, Volume: 38, Issue:3 Topics: Animals; Bacterial Infections; Disease Models, Animal; Escherichia coli; Female; Gentamicins; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Netilmicin; Neutropenia; Staphylococcus aureus; Thigh; Time Factors	1992
[Fluorescence polarization immunoassay of isepamicin in blood spotted on filter paper]. The Japanese journal of antibiotics, 1992, Volume: 45, Issue:7 Topics: Animals; Blood Specimen Collection; Filtration; Fluorescence Polarization Immunoassay; Gentamicins; Guinea Pigs; Humans	1992
[Mechanisms of resistance to dactimicin and isepamicin in clinical strains of gram-negative rods isolated in Czechoslovakia]. Bratislavske lekarske listy, 1992, Volume: 93, Issue:3 Topics: Aminoglycosides; Anti-Bacterial Agents; Czechoslovakia; Drug Resistance, Microbial; Gentamicins; Gram-Negative Bacteria; Health Facilities	1992
Increase of sensitivity to aminoglycoside antibiotics by polyamine-induced protein (oligopeptide-binding protein) in Escherichia coli. Journal of bacteriology, 1992, Volume: 174, Issue:13 Topics: Amino Acid Sequence; Aminoglycosides; Bacterial Proteins; Carrier Proteins; Chromosome Deletion; Escherichia coli; Escherichia coli Proteins; Gentamicins; Hydrogen-Ion Concentration; Kinetics; Lipoproteins; Magnesium; Molecular Sequence Data; Oligopeptides; Potassium; Spermidine; Structure-Activity Relationship	1992
Isepamicin disposition in subjects with various degrees of renal function. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:11 Topics: Adult; Aged; Female; Gentamicins; Humans; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Male; Middle Aged; Renal Dialysis	1991
Effect of isepamicin dosing scheme on concentration in cochlear tissue. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:11 Topics: Animals; Cochlea; Cochlear Nerve; Computer Simulation; Ear, Inner; Evoked Potentials, Auditory, Brain Stem; Gentamicins; Guinea Pigs; Hearing; Male; Sensory Thresholds	1991
Antimicrobial activity of isepamicin (SCH21420, 1-N-HAPA gentamicin B) combinations with cefotaxime, ceftazidime, ceftriaxone, ciprofloxacin, imipenem, mezlocillin and piperacillin tested against gentamicin-resistant and susceptible gram-negative bacilli Journal of chemotherapy (Florence, Italy), 1991, Volume: 3, Issue:5 Topics: Cefotaxime; Ceftazidime; Culture Media; Drug Interactions; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Enterobacteriaceae; Enterococcus; Gentamicins; Gram-Negative Bacteria; Imipenem; Mezlocillin; Piperacillin; Pseudomonas	1991
[Combination antibacterial effects between aztreonam and eight other antibiotics]. The Japanese journal of antibiotics, 1991, Volume: 44, Issue:1 Topics: Amoxicillin; Animals; Aztreonam; Bacterial Infections; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Female; Gentamicins; Mice; Microscopy, Phase-Contrast; Moxalactam; Proteus vulgaris; Pseudomonas aeruginosa; Serratia marcescens	1991
Efficacy of once- and thrice-daily dosing of aminoglycosides in in-vitro models of infection. The Journal of antimicrobial chemotherapy, 1991, Volume: 27 Suppl C Topics: Amikacin; Anti-Bacterial Agents; Drug Administration Schedule; Fluorescence Polarization Immunoassay; Gentamicins; Netilmicin; Pseudomonas aeruginosa; Serratia marcescens	1991
Comparative inactivation of isepamicin, amikacin, and gentamicin by nine beta-lactams and two beta-lactamase inhibitors, cilastatin and heparin. Antimicrobial agents and chemotherapy, 1991, Volume: 35, Issue:9 Topics: Amikacin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactams; Cilastatin; Drug Interactions; Fluorescence Polarization Immunoassay; Gentamicins; Heparin; Humans	1991
Simple measurement of isepamicin, a new aminoglycoside antibiotic, in guinea pig and human plasma, using high-performance liquid chromatography with ultraviolet detection. Therapeutic drug monitoring, 1991, Volume: 13, Issue:1 Topics: Animals; Chromatography, High Pressure Liquid; Gentamicins; Guinea Pigs; Humans; Radioimmunoassay; Reproducibility of Results; Ultraviolet Rays	1991
Post-antibiotic effect of isepamicin compared to that of other aminoglycosides. Drugs under experimental and clinical research, 1990, Volume: 16, Issue:5 Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Escherichia coli; Gentamicins; Microbial Sensitivity Tests; Netilmicin; Staphylococcus aureus; Time Factors	1990
In-vitro susceptibilities of gram-positive bacteria to cefpirome, vancomycin, isepamicin and gentamicin, singly and in combination. The Journal of antimicrobial chemotherapy, 1990, Volume: 26, Issue:6 Topics: Anti-Bacterial Agents; Cefpirome; Cephalosporins; Drug Therapy, Combination; Gentamicins; Gram-Positive Bacteria; Microbial Sensitivity Tests; Vancomycin	1990
Column liquid chromatographic determination of isepamicin in nasal cavity using gauze. Journal of chromatography, 1990, Aug-03, Volume: 529, Issue:2 Topics: 3-Mercaptopropionic Acid; Bacillus subtilis; Biological Assay; Chromatography, High Pressure Liquid; Gentamicins; Humans; Nasal Mucosa; o-Phthalaldehyde; Spectrometry, Fluorescence	1990
[An in vitro study on combination effect of isepamicin and beta-lactam antibiotics]. The Japanese journal of antibiotics, 1990, Volume: 43, Issue:9 Topics: Anti-Bacterial Agents; Cefoperazone; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Synergism; Drug Therapy, Combination; Gentamicins; Imipenem; Klebsiella pneumoniae; Microbial Sensitivity Tests; Moxalactam; Pseudomonas aeruginosa; Serratia marcescens	1990
[Pharmacokinetic and clinical studies on isepamicin in chronic complicated urinary tract infection using daily single dose treatment]. The Japanese journal of antibiotics, 1990, Volume: 43, Issue:9 Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Drug Administration Schedule; Drug Evaluation; Female; Gentamicins; Humans; Infusions, Intravenous; Male; Middle Aged; Urinary Bladder Neoplasms; Urinary Tract Infections	1990
Effect of dosing schedule on aminoglycoside ototoxicity: comparative cochlear ototoxicity of amikacin and isepamicin. ORL; journal for oto-rhino-laryngology and its related specialties, 1990, Volume: 52, Issue:6 Topics: Amikacin; Animals; Cochlea; Drug Administration Schedule; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Hair Cells, Auditory, Inner; Injections, Intramuscular; Organ of Corti; Vestibule, Labyrinth	1990
High-performance liquid chromatographic determination of isepamicin in plasma, urine and dialysate. Journal of chromatography, 1990, Apr-06, Volume: 526, Issue:2 Topics: Aminoglycosides; Analysis of Variance; Buffers; Chromatography, High Pressure Liquid; Dialysis Solutions; Gentamicins; Humans; Spectrometry, Fluorescence	1990
[Determination of isepamicin in the eluates from the dried blood spots on filter paper for monitoring of blood levels in a guinea-pig]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 1989, Volume: 109, Issue:12 Topics: Animals; Blood Specimen Collection; Fluorescent Antibody Technique; Gentamicins; Guinea Pigs; Injections, Intramuscular; Male; Paper	1989
[Comparison of HAPA-B and amikacin in the treatment of respiratory tract infections]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1986, Volume: 60, Issue:11 Topics: Adult; Aged; Aged, 80 and over; Amikacin; Gentamicins; Humans; Middle Aged; Respiratory Tract Infections	1986
[Fundamental and clinical studies on intravenous drip infusion of HAPA-B. Intravenous Drip Infusion HAPA-B research Group]. Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1986, Volume: 60, Issue:11 Topics: Bacterial Infections; Gentamicins; Humans; Infusions, Intravenous	1986
[Synergistic activity of isepamicin and beta-lactam antibiotics against Pseudomonas aeruginosa in vitro and in vivo]. The Japanese journal of antibiotics, 1988, Volume: 41, Issue:11 Topics: Animals; Anti-Bacterial Agents; Cefotaxime; Drug Synergism; Drug Therapy, Combination; Gentamicins; Male; Mice; Mice, Inbred ICR; Peritonitis; Piperacillin; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Tract Infections	1988
Evaluation of a fluorescence polarization immunoassay procedure for quantitation of isepamicin, a new aminoglycoside antibiotic. Therapeutic drug monitoring, 1988, Volume: 10, Issue:4 Topics: Adult; Amikacin; Bilirubin; Biological Assay; Chromatography, High Pressure Liquid; Drug Interactions; Gentamicins; Hemolysis; Humans; Immunoassay; Male; Reproducibility of Results; Tobramycin	1988
[Evaluation of assay methods for isepamicin sulfate (HAPA-B) in body fluids. Bioassay, HPLC and EIA methods]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Aminoglycosides; Biological Assay; Body Fluids; Chromatography, High Pressure Liquid; Gentamicins; Humans; Immunoenzyme Techniques; Kinetics	1987
[Mutation frequency test for isepamicin (HAPA-B)]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Escherichia coli; Gentamicins; Mutagenicity Tests; Mutation; Salmonella typhimurium	1986
[Toxicological studies on isepamicin (HAPA-B). I. Acute toxicity test in the mouse, rat and dog]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Administration, Oral; Amikacin; Animals; Dogs; Female; Gentamicins; Injections, Intramuscular; Injections, Intravenous; Lethal Dose 50; Male; Mice; Rats	1986
[Toxicological studies on isepamicin (HAPA-B). II. Intramuscular subacute toxicity test in the rat]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Amikacin; Animals; Body Weight; Dose-Response Relationship, Drug; Female; Gentamicins; Injections, Intramuscular; Kidney; Male; Rats	1986
[Toxicological studies on isepamicin (HAPA-B). IV. Intramuscular subacute toxicity test in the dog]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Amikacin; Animals; Dogs; Dose-Response Relationship, Drug; Female; Gentamicins; Injections, Intramuscular; Kidney; Male; Organ Size	1986
[Toxicological studies on isepamicin (HAPA-B). VII. Chronic intramuscular test in the rat]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Amikacin; Animals; Blood Chemical Analysis; Dose-Response Relationship, Drug; Female; Gentamicins; Injections, Intramuscular; Kidney; Male; Organ Size; Rats	1986
[Effect of isepamicin (HAPA-B) on reproduction. I. Fertility study in rats (intramuscular administration)]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Animals; Body Weight; Female; Fertility; Gentamicins; Injections, Intramuscular; Male; Pregnancy; Pregnancy, Animal; Rats	1986
[Effect of isepamicin (HAPA-B) on reproduction. II. Teratological study in rats (intramuscular administration)]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Abnormalities, Drug-Induced; Animals; Female; Fertility; Fetus; Gentamicins; Injections, Intramuscular; Male; Pregnancy; Pregnancy, Animal; Rats	1986
[Effect of isepamicin (HAPA-B) on reproduction. IV. Peri- and post-natal study in rats (intramuscular administration)]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Animals; Animals, Newborn; Behavior, Animal; Body Weight; Feeding Behavior; Female; Gentamicins; Injections, Intramuscular; Male; Pregnancy; Pregnancy, Animal; Rats	1986
[Immunological properties of isepamicin (HAPA-B)]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Animals; Antibody Formation; Cross Reactions; Gentamicins; Guinea Pigs; Immunoglobulin E; Immunoglobulin G; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Rabbits	1986
[Mutagenicity tests for isepamicin (HAPA-B)]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Animals; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Repair; Gentamicins; Mutagenicity Tests; Mutation; Salmonella	1986
[Local irritation study with isepamicin]. The Japanese journal of antibiotics, 1986, Volume: 39, Issue:12 Topics: Animals; Atrophy; Blood Vessels; Edema; Fibrosis; Gentamicins; Hemorrhage; Injections, Intramuscular; Male; Muscles; Necrosis; Rabbits	1986
[The neuromuscular blocking activity of isepamicin sulfate (HAPA-B) compared with other aminoglycoside antibiotics]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Amikacin; Aminoglycosides; Animals; Dose-Response Relationship, Drug; Gentamicins; In Vitro Techniques; Infusions, Intravenous; Male; Neuromuscular Blocking Agents; Rats; Rats, Inbred Strains	1987
[General pharmacological studies on isepamicin sulfate (HAPA-B)]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Aminoglycosides; Anesthetics, Local; Animals; Autonomic Nervous System; Blood Coagulation; Cats; Central Nervous System; Digestive System; Dogs; Female; Gentamicins; Guinea Pigs; Hemodynamics; In Vitro Techniques; Male; Mice; Rabbits; Rats; Respiration; Urogenital System	1987
[Studies on the metabolic fate of isepamicin sulfate (HAPA-B). I. Absorption, distribution, metabolism and excretion in rats]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Aminoglycosides; Animals; Female; Gentamicins; Half-Life; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Rats; Rats, Inbred Strains; Tissue Distribution	1987
[Studies on the metabolic fate of isepamicin sulfate (HAPA-B). II. Accumulation of HAPA-B after multiple administration in rats]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Aminoglycosides; Animals; Gentamicins; Injections, Intramuscular; Injections, Intravenous; Male; Rats; Rats, Inbred Strains; Tissue Distribution	1987
[Studies on the metabolic fate of isepamicin sulfate (HAPA-B). III. Intramuscular, intravenous and drip intravenous administration of HAPA-B in rabbits]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Aminoglycosides; Animals; Gentamicins; Infusions, Intravenous; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Models, Biological; Rabbits; Tissue Distribution	1987
[Studies on the metabolic fate of isepamicin sulfate (HAPA-B). IV. Intramuscular, intravenous and drip intravenous administration of HAPA-B in dogs]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Aminoglycosides; Animals; Dogs; Gentamicins; Infusions, Intravenous; Injections, Intramuscular; Injections, Intravenous; Kinetics; Male; Models, Biological	1987
[Studies on the metabolic fate of isepamicin sulfate (HAPA-B). V. Plasma concentrations of HAPA-B in dogs after multiple administrations]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Amikacin; Aminoglycosides; Animals; Dogs; Female; Gentamicins; Injections, Intramuscular; Kinetics; Male; Models, Biological	1987
[Metabolic fate of 14C-isepamicin sulfate (14C-HAPA-B) in rats. I. Absorption, distribution, metabolism and excretion after a single intramuscular and intravenous administration]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Aminoglycosides; Animals; Autoradiography; Blood Proteins; Carbon Radioisotopes; Gentamicins; Injections, Intramuscular; Injections, Intravenous; Male; Protein Binding; Rats; Rats, Inbred Strains; Tissue Distribution	1987
[Metabolic fate of 14C-isepamicin sulfate (14C-HAPA-B) in rats. II. Distribution and excretion after the successive administration]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Aminoglycosides; Animals; Autoradiography; Carbon Radioisotopes; Gentamicins; Injections, Intramuscular; Male; Rats; Rats, Inbred Strains; Tissue Distribution	1987
[Metabolic fate of 14C-isepamicin sulfate (14C-HAPA-B) in rats. III. Placental transfer and excretion into milk]. The Japanese journal of antibiotics, 1987, Volume: 40, Issue:1 Topics: Aminoglycosides; Animals; Autoradiography; Carbon Radioisotopes; Female; Fetus; Gentamicins; Maternal-Fetal Exchange; Milk; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Tissue Distribution	1987
Activity of amikacin, gentamicin and Schering 21420 when combined with carbenicillin or piperacillin against Pseudomonas aeruginosa. Chemotherapy, 1982, Volume: 28, Issue:4 Topics: Amikacin; Aminoglycosides; Carbenicillin; Drug Synergism; Gentamicins; Penicillins; Piperacillin; Pseudomonas aeruginosa	1982
Comparative study of the effects of sagamicin, 1 N-HABA-sagamicin, UK-4, Sch 21420, gentamicin and amikacin on the respiration activity of isolated rat kidney mitochondria. The Journal of antibiotics, 1980, Volume: 33, Issue:11 Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; In Vitro Techniques; Kanamycin; Kidney; Mitochondria; Oxygen Consumption; Rats; Structure-Activity Relationship	1980
Comparison of in vitro activity of Sch 21420, a gentamicin B derivative, with those of amikacin, gentamicin, netilmicin, sisomicin, and tobramycin. Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:2 Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Gentamicins; Microbial Sensitivity Tests; Netilmicin; Sisomicin; Tobramycin	1980
Interpretive standards for disk susceptibility tests with Sch 21420 and amikacin. Antimicrobial agents and chemotherapy, 1980, Volume: 18, Issue:4 Topics: Amikacin; Bacteria; Gentamicins; Kanamycin; Microbial Sensitivity Tests; Regression Analysis	1980
[Reevaluation of current antimicrobials. Series 25: isepamicin]. The Japanese journal of antibiotics, 1995, Volume: 48, Issue:1 Topics: Bacterial Infections; Cystitis; Gentamicins; Humans; Microbial Sensitivity Tests; Respiratory Tract Infections	1995
[Post-antibiotic effect of three aminoglycosides against Klebsiella pneumoniae]. Pathologie-biologie, 1994, Volume: 42, Issue:5 Topics: Amikacin; Dose-Response Relationship, Drug; Filtration; Gentamicins; In Vitro Techniques; Klebsiella pneumoniae; Netilmicin	1994
[Bactericidal activities of isepamicin and ofloxacin against Pseudomonas aeruginosa evaluated using an in vitro pharmacokinetic simulation system]. The Japanese journal of antibiotics, 1994, Volume: 47, Issue:8 Topics: Adult; Computer Simulation; Drug Synergism; Gentamicins; Humans; Microbial Sensitivity Tests; Ofloxacin; Pseudomonas aeruginosa	1994
[Antibacterial activities of isepamicin against fresh clinical isolates of gram-negative bacilli]. The Japanese journal of antibiotics, 1994, Volume: 47, Issue:8 Topics: Drug Resistance, Microbial; Drug Resistance, Multiple; Gentamicins; Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests	1994
Serotypes and extended spectrum beta-lactam resistance in aminoglycoside resistant Pseudomonas aeruginosa isolates from two Belgian general hospitals: a seven year study. The Journal of hospital infection, 1993, Volume: 24, Issue:2 Topics: Amikacin; Anti-Bacterial Agents; Belgium; beta-Lactams; Cross Infection; Drug Resistance, Microbial; Gentamicins; Hospitals; Humans; Pseudomonas aeruginosa; Serotyping	1993
Activity of isepamicin and selection of permeability mutants to beta-lactams during aminoglycoside therapy of experimental endocarditis due to Klebsiella pneumoniae CF104 producing an aminoglycoside acetyltransferase 6' modifying enzyme and a TEM-3 beta-l The Journal of infectious diseases, 1994, Volume: 169, Issue:6 Topics: Acetyltransferases; Amikacin; Animals; Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; beta-Lactamases; beta-Lactams; Cell Membrane Permeability; Disease Models, Animal; Drug Therapy, Combination; Endocarditis; Female; Gentamicins; Klebsiella pneumoniae; Mutation; Rabbits	1994
Influence of circadian-stage-dependent dosing schedule on nephrotoxicity and pharmacokinetics of isepamicin in rats. Antimicrobial agents and chemotherapy, 1993, Volume: 37, Issue:9 Topics: Animals; Anti-Bacterial Agents; Circadian Rhythm; Gentamicins; Injections, Subcutaneous; Kidney Diseases; Rats; Rats, Wistar	1993
Effect of hemodialysis on serum concentration of isepamicin in a patient with endstage renal failure. The Annals of pharmacotherapy, 1993, Volume: 27, Issue:10 Topics: Aged; Gentamicins; Half-Life; Humans; Kidney Failure, Chronic; Male; Metabolic Clearance Rate; Renal Dialysis	1993
Population pharmacokinetic analysis of new aminoglycosides, astromicin and isepamicin, and evaluation of Bayesian prediction method for approximation of individual clearance of drug. International journal of clinical pharmacology, therapy, and toxicology, 1993, Volume: 31, Issue:12 Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Bayes Theorem; Gentamicins; Humans; Male; Metabolic Clearance Rate; Middle Aged	1993
Pharmacokinetics and metabolism of 14C-isepamicin in humans following intravenous administration. Antimicrobial agents and chemotherapy, 1995, Volume: 39, Issue:10 Topics: Adult; Anti-Bacterial Agents; Carbon Radioisotopes; Gentamicins; Humans; Injections, Intravenous; Male	1995
Isepamicin Once a Day--Enhancing Traditional Aminoglycoside Therapy. Proceedings of a meeting. Rotherwick, England, September 24-25, 1994. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Anti-Bacterial Agents; Gentamicins; Humans	1995
The changing nature of aminoglycoside resistance mechanisms and the role of isepamicin--a new broad-spectrum aminoglycoside. The Aminoglycoside Resistance Study Groups. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Acetyltransferases; Anti-Bacterial Agents; Carbohydrate Sequence; Drug Resistance, Microbial; Gentamicins; Gram-Negative Bacteria; Gram-Positive Bacteria; Molecular Sequence Data	1995
Pharmacokinetics of isepamicin in paediatric patients. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Adolescent; Aging; Anti-Bacterial Agents; Child; Child, Preschool; Gentamicins; Humans; Infant; Infant, Newborn; Microbial Sensitivity Tests	1995
Auditory impairment in guinea pigs treated with isepamicin. Journal of chemotherapy (Florence, Italy), 1995, Volume: 7 Suppl 2 Topics: Amikacin; Animals; Anti-Bacterial Agents; Auditory Threshold; Body Weight; Brain; Cochlear Duct; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Evoked Potentials, Auditory, Brain Stem; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Hearing Disorders; Male; Microscopy, Electron, Scanning	1995
Aminoglycoside antibiotics prevent the formation of non-bilayer structures in negatively-charged membranes. Comparative studies using fusogenic (bis(beta-diethylaminoethylether)hexestrol) and aggregating (spermine) agents. Chemistry and physics of lipids, 1996, Mar-29, Volume: 79, Issue:2 Topics: Animals; Anti-Bacterial Agents; Electrochemistry; Gentamicins; Hexestrol; In Vitro Techniques; Kidney; Liposomes; Magnetic Resonance Spectroscopy; Membrane Fusion; Membrane Lipids; Molecular Conformation; Spermine; Thermodynamics	1996
[Antibacterial activities of combination uses of isepamicin and beta-lactams in vitro against clinically isolated strains. Part 1. Activities against Staphylococcus aureus]. The Japanese journal of antibiotics, 1996, Volume: 49, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Infections; Cefazolin; Cefotiam; Cephalosporins; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gentamicins; Humans; Methicillin Resistance; Staphylococcus aureus	1996
[Antibacterial activities of combination uses of isepamicin and beta-lactams in vitro against clinically isolated strains. Part 3. The results against Pseudomonas aeruginosa]. The Japanese journal of antibiotics, 1996, Volume: 49, Issue:5 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Synergism; Drug Therapy, Combination; Gentamicins; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa	1996
Population pharmacokinetic study of isepamicin with intensive care unit patients. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Gentamicins; Humans; Intensive Care Units; Linear Models; Middle Aged	1996
Temporal variation in nephrotoxicity of low doses of isepamicin in rats. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:3 Topics: Animals; Anti-Bacterial Agents; Body Weight; Circadian Rhythm; Gentamicins; Immunohistochemistry; Injections, Intraperitoneal; Kidney Cortex; Kidney Diseases; Kidney Tubules, Proximal; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Regeneration; Thymidine; Time Factors	1996
[Antibacterial activities of combination uses of isepamicin and beta-lactams in vitro against clinically isolated strains. Part 2. The results against enterobacteriaceae]. The Japanese journal of antibiotics, 1996, Volume: 49, Issue:3 Topics: Anti-Bacterial Agents; beta-Lactams; Drug Synergism; Enterobacter cloacae; Enterobacteriaceae; Gentamicins; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests	1996
Resistance to amikacin and isepamicin in rabbits with experimental endocarditis of an aac(6')-Ib-bearing strain of Klebsiella pneumoniae susceptible in vitro. Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:12 Topics: Acetyltransferases; Amikacin; Animals; Anti-Bacterial Agents; Colony Count, Microbial; Drug Resistance, Microbial; Endocarditis; Female; Genes, Bacterial; Gentamicins; Klebsiella Infections; Klebsiella pneumoniae; Male; Mice; Rabbits	1996
Analysis of isepamicin in human plasma by radioimmunoassay, microbiologic assay, and high-performance liquid chromatography. Therapeutic drug monitoring, 1997, Volume: 19, Issue:6 Topics: Anti-Bacterial Agents; Biological Assay; Chromatography, High Pressure Liquid; Drug Monitoring; Gentamicins; Humans; Radioimmunoassay	1997
Single-dose pharmacokinetics of isepamicin in young and geriatric volunteers. Journal of clinical pharmacology, 1997, Volume: 37, Issue:11 Topics: Adult; Age Factors; Aged; Anti-Bacterial Agents; Area Under Curve; Female; Gentamicins; Humans; Male; Metabolic Clearance Rate; Middle Aged; Sex Factors	1997
Solution studies of isepamicin and conformational comparisons between isepamicin and butirosin A when bound to an aminoglycoside 6'-N-acetyltransferase determined by NMR spectroscopy. Biochemistry, 1998, Mar-17, Volume: 37, Issue:11 Topics: Acetyltransferases; Binding Sites; Butirosin Sulfate; Enterococcus faecium; Gentamicins; Kinetics; Magnetic Resonance Spectroscopy; Protein Conformation; Solutions; Substrate Specificity	1998
Postanitbiotic and sub-MIC effects of azithromycin and isepamicin against Staphylococcus aureus and Escherichia coli. Antimicrobial agents and chemotherapy, 1998, Volume: 42, Issue:2 Topics: Animals; Anti-Bacterial Agents; Azithromycin; Escherichia coli; Female; Gentamicins; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Staphylococcus aureus	1998
[Sensitivity of Pseudomonas aeruginosa to amikacin and to isepamicin in surgery and in intensive care]. Pathologie-biologie, 1997, Volume: 45, Issue:9 Topics: Amikacin; Anti-Bacterial Agents; Cross Infection; Drug Resistance, Microbial; Gentamicins; Humans; Intensive Care Units; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Surgery Department, Hospital	1997
Treatment of osteomyelitis with antibiotic-soaked porous glass ceramic. The Journal of bone and joint surgery. British volume, 1998, Volume: 80, Issue:3 Topics: Adult; Animals; Anti-Bacterial Agents; Apatites; Arthroplasty, Replacement, Hip; Calcium Compounds; Cefmetazole; Cephamycins; Ceramics; Drug Delivery Systems; Drug Implants; Drug Therapy, Combination; Durapatite; Female; Femur; Gentamicins; Glass; Hip Prosthesis; Humans; Male; Middle Aged; Osteomyelitis; Pilot Projects; Porosity; Prosthesis-Related Infections; Rabbits; Silicates; Tibia; Time Factors	1998
Protective effect of ceftriaxone against the nephrotoxicity of isepamicin administered once daily in rats. Biological & pharmaceutical bulletin, 1998, Volume: 21, Issue:5 Topics: Animals; Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Creatinine; Gentamicins; Hexosaminidases; Kidney Cortex; Kidney Diseases; Male; Rats; Rats, Wistar	1998
Relationship between spontaneous aminoglycoside resistance in Escherichia coli and a decrease in oligopeptide binding protein. Journal of bacteriology, 1998, Volume: 180, Issue:20 Topics: Amino Acids; Anti-Bacterial Agents; Bacterial Proteins; Biological Transport; Carrier Proteins; Down-Regulation; Escherichia coli; Escherichia coli Proteins; Gentamicins; Kanamycin; Kanamycin Resistance; Lipoproteins; Mutagenesis; Peptides; Polyamines	1998
Antibiotic-loaded porous hydroxyapatite blocks for the treatment of osteomyelitis and postoperative infection. A preliminary report. Bulletin (Hospital for Joint Diseases (New York, N.Y.)), 1998, Volume: 57, Issue:3 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Biocompatible Materials; Combined Modality Therapy; Curettage; Drug Implants; Durapatite; Female; Follow-Up Studies; Gentamicins; Humans; Infusions, Intravenous; Joint Prosthesis; Male; Osteomyelitis; Porosity; Prosthesis-Related Infections; Radiography; Treatment Outcome	1998
Rabbits treated with chronic isepamicin are resistant to mivacurium and rocuronium. Anesthesia and analgesia, 1999, Volume: 88, Issue:3 Topics: Androstanols; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Drug Synergism; Female; Gentamicins; Isoquinolines; Male; Mivacurium; Neuromuscular Nondepolarizing Agents; Rabbits; Rocuronium	1999
[Effects of isepamicin and beta-lactam antibiotics on the release of endotoxin from Pseudomonas aeruginosa]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:1 Topics: Anti-Bacterial Agents; Ceftazidime; Cephalosporins; Endotoxins; Gentamicins; Imipenem; Penicillins; Piperacillin; Pseudomonas aeruginosa; Thienamycins	1999
[Neuromuscular blocking properties of arbekacin, astromicin, isepamicin and netilmicin in the rabbit]. The Japanese journal of antibiotics, 1999, Volume: 52, Issue:8 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Dibekacin; Dose-Response Relationship, Drug; Gentamicins; Netilmicin; Neuromuscular Blocking Agents; Rabbits; Tubocurarine	1999
Apoptosis in renal proximal tubules of rats treated with low doses of aminoglycosides. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3 Topics: Amikacin; Animals; Anti-Bacterial Agents; Apoptosis; Blood Urea Nitrogen; Cell Division; Creatinine; Female; Gentamicins; In Situ Nick-End Labeling; Kidney Cortex; Kidney Tubules, Proximal; Netilmicin; Phospholipids; Rats; Rats, Wistar	2000
[The resistance of recent clinical isolates against isepamycin, other aminoglycosides and injectable beta-lactams]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:1 Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Ceftazidime; Dibekacin; Drug Resistance, Microbial; Gentamicins; Humans; Imipenem; Piperacillin; Tobramycin	2000
[In vitro interaction of piperacillin and imipenem/cilastatin combined with aminoglycosides against Pseudomonas aeruginosa]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:4 Topics: Amikacin; Anti-Bacterial Agents; Cilastatin; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Gentamicins; Imipenem; Netilmicin; Penicillins; Piperacillin; Pseudomonas aeruginosa; Tobramycin	2000
Determination of isepamicin sulfate and related compounds by high performance liquid chromatography using evaporative light scattering detection. Journal of pharmaceutical and biomedical analysis, 2001, Volume: 24, Issue:3 Topics: Anti-Bacterial Agents; Carbohydrate Conformation; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Gentamicins; Light; Molecular Sequence Data; Reproducibility of Results; Scattering, Radiation; Sensitivity and Specificity	2001
[Concentration of isepamicin sulfate in bone marrow blood]. The Japanese journal of antibiotics, 2000, Volume: 53, Issue:9 Topics: Adult; Aged; Anti-Bacterial Agents; Biological Transport; Bone Marrow; Female; Gentamicins; Humans; Infusions, Intravenous; Male; Middle Aged; Rotator Cuff; Rotator Cuff Injuries; Surgical Wound Infection; Time Factors	2000
Comparative activities of isepamicin, amikacin, cefepime, and ciprofloxacin alone or in combination with other antibiotics against Stenotrophomonas maltophilia. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2001, Volume: 20, Issue:1 Topics: Amikacin; Anti-Bacterial Agents; Anti-Infective Agents; Cefepime; Cephalosporins; Ciprofloxacin; Colony Count, Microbial; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Gentamicins; Gram-Negative Bacterial Infections; Microbial Sensitivity Tests; Stenotrophomonas maltophilia; Time Factors	2001
Cloning, overexpression, and purification of aminoglycoside antibiotic nucleotidyltransferase (2'')-Ia: conformational studies with bound substrates. Biochemistry, 2001, Jun-19, Volume: 40, Issue:24 Topics: Bacterial Proteins; Binding Sites; Cloning, Molecular; Escherichia coli; Gene Expression Regulation, Bacterial; Gentamicins; Kanamycin; Kanamycin Resistance; Nuclear Magnetic Resonance, Biomolecular; Nucleotidyltransferases; Protein Binding; Protein Conformation; Pseudomonas aeruginosa; RNA, Bacterial; Substrate Specificity	2001
Neuromuscular blocking effects of the aminoglycoside antibiotics arbekacin, astromicin, isepamicin and netilmicin on the diaphragm and limb muscles in the rabbit. Pharmacology, 2001, Volume: 63, Issue:3 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Diaphragm; Dibekacin; Dose-Response Relationship, Drug; Gentamicins; In Vitro Techniques; Male; Muscle Contraction; Muscle, Skeletal; Netilmicin; Neuromuscular Junction; Rabbits	2001
[In vitro interaction of tazobactam/piperacillin combined with aminoglycosides against Pseudomonas aeruginosa, Klebsiella pneumoniae, Escherichia coli AND Staphylococcus aureus]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:1 Topics: Amikacin; Anti-Bacterial Agents; Drug Antagonism; Drug Combinations; Drug Resistance, Bacterial; Drug Synergism; Enzyme Inhibitors; Escherichia coli; Gentamicins; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Piperacillin; Pseudomonas aeruginosa; Staphylococcus aureus; Tazobactam	2002
Protective effect of fleroxacin against the nephrotoxicity of isepamicin in rats. Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:4 Topics: Acetylglucosaminidase; Animals; Blood Urea Nitrogen; Creatinine; Drug Therapy, Combination; Fleroxacin; Gentamicins; Kidney; Kidney Tubular Necrosis, Acute; Kidney Tubules, Proximal; Male; Rats; Rats, Wistar	2002
Diffusion of isepamicin into cancellous and cortical bone tissue. Journal of chemotherapy (Florence, Italy), 2002, Volume: 14, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Biological Availability; Bone and Bones; Female; Gentamicins; Hip; Humans; Infusions, Intravenous; Male; Microbial Sensitivity Tests; Middle Aged	2002
[Antibacterial activities and PK/PD parameters of aminoglycosides against recent clinical isolates of gram-negative rods]. The Japanese journal of antibiotics, 2002, Volume: 55, Issue:5 Topics: Amikacin; Anti-Bacterial Agents; Dibekacin; Drug Resistance, Microbial; Gentamicins; Gram-Negative Bacteria; Humans; Netilmicin; Tobramycin	2002
[Iliopsoas abscess accompanied by epidural abscess--a case report]. Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:9 Topics: Anti-Bacterial Agents; Drainage; Epidural Abscess; Gentamicins; Humans; Low Back Pain; Magnetic Resonance Imaging; Male; Middle Aged; Psoas Abscess; Treatment Outcome	2003
A case of Pasteurella haemolytica sepsis in a patient with mitral valve disease who developed a splenic abscess. Scandinavian journal of infectious diseases, 2003, Volume: 35, Issue:10 Topics: Abscess; Adult; Anti-Bacterial Agents; Gentamicins; Humans; Male; Mannheimia haemolytica; Pasteurellaceae Infections; Spleen; Splenic Diseases	2003
Deficiency of polycystin-2 reduces Ca2+ channel activity and cell proliferation in ADPKD lymphoblastoid cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:7 Topics: Amino Acid Substitution; B-Lymphocytes; Calcium; Calcium Signaling; Cell Division; Cell Line, Transformed; Codon, Nonsense; Endoplasmic Reticulum; Gentamicins; Humans; Ion Transport; Kidney; Membrane Proteins; Mutation, Missense; Organ Specificity; Platelet Activating Factor; Point Mutation; Polycystic Kidney, Autosomal Dominant; Proteins; RNA, Messenger; Suppression, Genetic; TRPP Cation Channels	2004
High release of antibiotic from a novel hydroxyapatite with bimodal pore size distribution. Journal of biomedical materials research. Part B, Applied biomaterials, 2004, Aug-15, Volume: 70, Issue:2 Topics: Adsorption; Animals; Anti-Bacterial Agents; Cephalosporins; Delayed-Action Preparations; Drug Carriers; Durapatite; Female; Femur; Gentamicins; Microscopy, Electron, Scanning; Nanostructures; Porosity; Prostheses and Implants; Rabbits; Vancomycin	2004
[Aminoglycoside resistance in gramnegative pathogens of nosocomial infections in Russia]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2004, Volume: 49, Issue:5 Topics: Acetyltransferases; Aminoglycosides; Anti-Bacterial Agents; Cross Infection; Drug Resistance, Bacterial; Gentamicins; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Infection Control; Nucleotidyltransferases; Phosphotransferases; Russia; Substrate Specificity	2004
A case of pneumonia caused by Ewingella americana in a patient with chronic renal failure. Journal of Korean medical science, 2005, Volume: 20, Issue:1 Topics: Adult; Anti-Bacterial Agents; Ceftriaxone; Enterobacteriaceae; Enterobacteriaceae Infections; Gentamicins; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Pneumonia; Sputum; Time Factors	2005
In vitro activity of isepamicin against Pseudomomas aeruginosa and Enterobacter cloacae strains resistant to amikacin: a preliminary report. Journal of chemotherapy (Florence, Italy), 1989, Volume: 1, Issue:4 Suppl Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterobacter cloacae; Gentamicins; Microbial Sensitivity Tests; Pseudomonas aeruginosa	1989
In vitro activities of tigecycline, ertapenem, isepamicin, and other antimicrobial agents against clinically isolated organisms in Taiwan. Microbial drug resistance (Larchmont, N.Y.), 2005,Winter, Volume: 11, Issue:4 Topics: Anti-Bacterial Agents; Bacteria; beta-Lactams; Drug Resistance, Bacterial; Ertapenem; Gentamicins; Hospitals, University; Microbial Sensitivity Tests; Minocycline; Taiwan; Tigecycline	2005
[Isepamycin in prophylaxis and treatment of experimental plague due to FI+ and FI- variants of plague microbe]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2005, Volume: 50, Issue:8-9 Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Bacterial Proteins; Gentamicins; Mice; Mice, Inbred Strains; Mutation; Plague; Yersinia pestis	2005
In Vitro activities of isepamicin, other aminoglycosides, and capreomycin against clinical isolates of rapidly growing mycobacteria in Taiwan. Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:5 Topics: Aminoglycosides; Anti-Bacterial Agents; Capreomycin; Gentamicins; Humans; Microbial Sensitivity Tests; Mycobacterium chelonae; Mycobacterium fortuitum; Nontuberculous Mycobacteria	2007
In vitro activity of isepamicin and other aminoglycosides against clinical isolates of Gram-negative bacteria causing nosocomial bloodstream infections. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2007, Volume: 40, Issue:6 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteremia; Cross Infection; Gentamicins; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Taiwan	2007
Research and clinical value of antibacterial-application software. Chinese medical journal, 2008, Jan-05, Volume: 121, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefepime; Cephalosporins; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Gentamicins; Humans; Imipenem; Isosorbide Dinitrate; Male; Ofloxacin; Software	2008
Apoptosis induced by aminoglycosides in LLC-PK1 Cells: comparative study of neomycin, gentamicin, amikacin, and isepamicin using electroporation. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:6 Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Apoptosis; Electroporation; Gentamicins; LLC-PK1 Cells; Neomycin; Swine	2008
Determination of isepamicin in human plasma by HPLC with fluorescence detection after derivatization using 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate. Biological & pharmaceutical bulletin, 2008, Volume: 31, Issue:10 Topics: Amikacin; Aminoquinolines; Anti-Bacterial Agents; Carbamates; Carbohydrate Sequence; Chromatography, High Pressure Liquid; Gentamicins; Humans; Indicators and Reagents; Molecular Sequence Data; Reproducibility of Results; Spectrometry, Fluorescence	2008
Prophylactic use of isepamicin and levofloxacin for transrectal prostate biopsy: a retrospective single center study. International journal of urology : official journal of the Japanese Urological Association, 2009, Volume: 16, Issue:9 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Biopsy; Drug Therapy, Combination; Gentamicins; Humans; Levofloxacin; Male; Ofloxacin; Prostate; Prostatitis; Rectum; Retrospective Studies; Risk Factors; Ultrasound, High-Intensity Focused, Transrectal	2009
Mutant APH(2'')-IIa enzymes with increased activity against amikacin and isepamicin. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:4 Topics: Aged; Amikacin; Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Directed Molecular Evolution; DNA Primers; DNA, Bacterial; Drug Resistance, Bacterial; Escherichia coli; Gentamicins; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis; Mutation; Phosphotransferases (Alcohol Group Acceptor); Protein Structure, Tertiary; Recombinant Proteins; Sequence Homology, Amino Acid	2010
Antibiotic and synergistic effect of Leu-Lys rich peptide against antibiotic resistant microorganisms isolated from patients with cholelithiasis. Biochemical and biophysical research communications, 2010, Sep-03, Volume: 399, Issue:4 Topics: Amino Acid Sequence; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cell Line; Cephalosporins; Cholelithiasis; Drug Resistance, Bacterial; Drug Synergism; Gentamicins; Humans; Melitten; Molecular Sequence Data; Pseudomonas aeruginosa	2010
In vitro susceptibility of nosocomial isolates against a new aminoglycoside isepamicin. The Indian journal of medical research, 2001, Volume: 113 Topics: Anti-Bacterial Agents; Bacterial Infections; Cross Infection; Drug Resistance, Bacterial; Gentamicins; Humans; In Vitro Techniques; India; Microbial Sensitivity Tests	2001
Necrotic intramuscular chloroma with infection: magnetic resonance imaging features. Japanese journal of radiology, 2011, Volume: 29, Issue:10 Topics: Anti-Bacterial Agents; Antimetabolites, Antineoplastic; Child; Contrast Media; Cytarabine; Diagnosis, Differential; Diffusion Magnetic Resonance Imaging; Gentamicins; Humans; Image Enhancement; Klebsiella Infections; Klebsiella pneumoniae; Leg; Leukemia, Myeloid, Acute; Magnetic Resonance Imaging; Male; Meropenem; Muscle Neoplasms; Necrosis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sarcoma, Myeloid; Teicoplanin; Thienamycins; Treatment Outcome	2011
In vitro antimicrobial susceptibility to isepamicin of 6,296 Enterobacteriaceae clinical isolates collected at a tertiary care university hospital in Greece. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6 Topics: Anti-Infective Agents; Enterobacteriaceae; Gentamicins; Greece; Humans; Microbial Sensitivity Tests	2012
Antimicrobial susceptibility of non-fermenting Gram-negative isolates to isepamicin in a region with high antibiotic resistance. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2012, Volume: 31, Issue:11 Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Gentamicins; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Greece; Humans; Microbial Sensitivity Tests; Prevalence	2012
In vitro activity of aminoglycosides against clinical isolates of Acinetobacter baumannii complex and other nonfermentative Gram-negative bacilli causing healthcare-associated bloodstream infections in Taiwan. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2016, Volume: 49, Issue:6 Topics: Acinetobacter baumannii; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacteremia; Burkholderia cepacia; Cross Infection; Drug Resistance, Bacterial; Gentamicins; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Stenotrophomonas maltophilia; Tobramycin	2016
In vitro activity of aminoglycosides, clofazimine, d-cycloserine and dapsone against 83 Mycobacterium avium complex clinical isolates. Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi, 2018, Volume: 51, Issue:5 Topics: Aminoglycosides; Anti-Bacterial Agents; Clarithromycin; Clofazimine; Cycloserine; Drug Synergism; Fluoroquinolones; Gentamicins; Humans; Linezolid; Microbial Sensitivity Tests; Microbial Viability; Moxifloxacin; Mycobacterium avium; Mycobacterium avium Complex; Mycobacterium avium-intracellulare Infection; Sputum; Streptomycin	2018
Complete reconstitution of the diverse pathways of gentamicin B biosynthesis. Nature chemical biology, 2019, Volume: 15, Issue:3 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Biosynthetic Pathways; Gene Expression; Gentamicins; Glycosyltransferases; Micromonospora; Substrate Specificity	2019
Efficacy of combined prophylactic use of levofloxacin and isepamicin for transrectal prostate needle biopsy: A retrospective single-center study. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2019, Volume: 25, Issue:5 Topics: Acute Disease; Administration, Intravenous; Administration, Oral; Aged; Antibiotic Prophylaxis; Bacteria; Biopsy, Large-Core Needle; Drug Therapy, Combination; Gentamicins; Humans; Incidence; Levofloxacin; Male; Postoperative Complications; Prostate; Prostatic Neoplasms; Prostatitis; Rectum; Retrospective Studies; Ultrasonography, Interventional	2019
Investigation of isepamicin in vitro efficiency in Gram negative bacteria efficacy of isepamicin. Indian journal of medical microbiology, 2021, Volume: 39, Issue:1 Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Gentamicins; Gram-Negative Bacteria; Microbial Sensitivity Tests; Netilmicin; Pseudomonas aeruginosa; Tobramycin	2021