gemfibrozil and simvastatin acid

gemfibrozil has been researched along with simvastatin acid in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Backman, JT; Kivistö, KT; Kyrklund, C; Neuvonen, PJ; Wang, JS1
Baillie, TA; Lin, JH; Liu, L; Ma, B; Pearson, PG; Prueksaritanont, T; Qiu, Y; Roadcap, BA; Tang, C; Zhao, JJ1
Brunner, J; Lin, JH; Michel, K; Mu, L; Prueksaritanont, T; Qiu, Y; Richards, KM1

Trials

1 trial(s) available for gemfibrozil and simvastatin acid

ArticleYear
Plasma concentrations of active simvastatin acid are increased by gemfibrozil.
    Clinical pharmacology and therapeutics, 2000, Volume: 68, Issue:2

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Female; Gemfibrozil; Humans; Hypolipidemic Agents; Male; Microsomes, Liver; Simvastatin

2000

Other Studies

2 other study(ies) available for gemfibrozil and simvastatin acid

ArticleYear
Mechanistic studies on metabolic interactions between gemfibrozil and statins.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:3

    Topics: Administration, Oral; Animals; Area Under Curve; Catalysis; Dogs; Drug Interactions; Gemfibrozil; Glucuronides; Glucuronosyltransferase; Humans; Hydrolysis; Hypolipidemic Agents; Isoenzymes; Microsomes, Liver; Oxidation-Reduction; Simvastatin

2002
Interconversion pharmacokinetics of simvastatin and its hydroxy acid in dogs: effects of gemfibrozil.
    Pharmaceutical research, 2005, Volume: 22, Issue:7

    Topics: Animals; Anticholesteremic Agents; Cells, Cultured; Dogs; Gemfibrozil; Hepatocytes; Humans; Hydrolysis; Hypolipidemic Agents; Infusions, Intravenous; Liver; Simvastatin

2005