gemfibrozil and pyrroles

gemfibrozil has been researched along with pyrroles in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (12.12)18.2507
2000's22 (66.67)29.6817
2010's7 (21.21)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Connor, WE; Duell, PB; Illingworth, DR1
Aviram, M; Bisgaier, CL; Newton, RS; Rosenblat, M1
Henry, K; Hermundson, J; Huebesch, J; Melroe, H; Simpson, J1
Frane, AM; Gantner, SE; Joyce, DM; Kersten, ME; Murdock, AK; Murdock, DK; Murdock, RW; Olson, KJ1
Currier, JS1
Stein, EA1
Black, DM1
Harangi, M; Paragh, G1
Breuer, HW1
Athyros, VG; Athyrou, VV; Demitriadis, DS; Kontopoulos, AG; Papageorgiou, AA; Pehlivanidis, AN1
Lin, JH; Mu, L; Prueksaritanont, T; Qiu, Y; Subramanian, R; Tang, C1
Bouzamondo, A; Corvol, JC; Hulot, JS; Lechat, P; Sanchez, P; Sirol, M1
Bonet, R; Jorba, O; Ordóñez-Llanos, J; Pérez, A; Wägner, AM1
Fujino, H; Hirano, M; Kojima, J; Shimada, S; Tsunenari, Y; Yamada, I1
Jorba, O; Ordóñez-Llanos, J; Pérez, A; Wägner, AM1
Ganda, OP1
Backman, JT; Luurila, H; Neuvonen, M; Neuvonen, PJ1
Balice, M; Chironi, G; Del-Pino, M; Gariepy, J; Levenson, J; Simon, A1
Dellavalle, RP; Drake, AL; Freeman, SR; Graber, M; Heilig, LF; McNealy, K; Schilling, LM1
Bauman, JN; Davis, JA; Goosen, TC; Hurst, SI; Loi, CM; Williams, JA; Yu, C1
Chan, D; Dogra, G; Irish, A; Watts, G1
Gratsianskii, NA; Vaulin, NA1
Dimitri, E; Landry, P; Légaré, N; Tessier, S1
Bari, AU; Hashim, R; Hussain, M; Rahman, SB1
Backman, JT; Kalliokoski, A; Kurkinen, KJ; Neuvonen, PJ; Niemi, M1
Frisbee, JC; Frisbee, SJ; Goodwill, AG; James, ME; Stapleton, PA1
Abel, R; Alvey, C; Bullen, W; Hartman, D; Porcari, AR; Whitfield, LR1
Archimandritis, A; Frenzilli, G; Peluso, C; Rocco, L; Stingo, V; Zito, G1
Anetseder, M; Hager, M; Metterlein, T; Roewer, N; Schuster, F; Tadda, L1
Awasthi, S; Nagaprashantha, L; Singhal, J; Singhal, SS; Vatsyayan, R1
Flores, RM; Kanth, R; Shah, MS1
Brown, E; Crane, HM; Delaney, JA; Eron, JJ; Hunt, PW; Kahn, JO; Kitahata, MM; Liu, W; Mathews, WC; Mugavero, MJ; Muñoz, MA; Napravnik, S; Saag, MS; Willig, JH1
Jacob, RF; Mason, RP1

Reviews

6 review(s) available for gemfibrozil and pyrroles

ArticleYear
Statins in children: what do we know and what do we need to do?
    Current atherosclerosis reports, 2001, Volume: 3, Issue:1

    Topics: Atorvastatin; Bezafibrate; Child; Child Welfare; Cost-Benefit Analysis; Drug Approval; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Pyridines; Pyrroles; Simvastatin

2001
[The role of HDL in the prevention of cardiovascular events].
    Orvosi hetilap, 2001, Jan-21, Volume: 142, Issue:3

    Topics: Anticholesteremic Agents; Arteriosclerosis; Aryldialkylphosphatase; Atorvastatin; Cholesterol, HDL; Esterases; Fatty Acids, Monounsaturated; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Lipid Peroxidation; Lovastatin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyrroles; Simvastatin

2001
Hypertriglyceridemia: a review of clinical relevance and treatment options: focus on cerivastatin.
    Current medical research and opinion, 2001, Volume: 17, Issue:1

    Topics: Atorvastatin; Coronary Disease; Drug Therapy, Combination; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Hypolipidemic Agents; Niacin; Pyridines; Pyrroles; Risk Factors; Triglycerides

2001
Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials.
    Archives of internal medicine, 2003, Mar-24, Volume: 163, Issue:6

    Topics: Anticholesteremic Agents; Atorvastatin; Cholestyramine Resin; Clofibrate; Colestipol; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Myocardial Infarction; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Regression Analysis; Risk Assessment; Risk Factors; Simvastatin; Stroke; Treatment Failure; Treatment Outcome

2003
The role of lipid management in diabetes.
    Cardiology clinics, 2005, Volume: 23, Issue:2

    Topics: Anticholesteremic Agents; Atorvastatin; Diabetes Mellitus; Diabetic Angiopathies; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins, HDL; Pyrroles; Simvastatin; Triglycerides

2005
Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.
    Journal of the National Cancer Institute, 2006, Nov-01, Volume: 98, Issue:21

    Topics: Atorvastatin; Bezafibrate; Clofibrate; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Incidence; Lovastatin; Melanoma; Odds Ratio; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Reproducibility of Results; Simvastatin; Skin Neoplasms; United States

2006

Trials

8 trial(s) available for gemfibrozil and pyrroles

ArticleYear
Atorvastatin versus four statin-fibrate combinations in patients with familial combined hyperlipidaemia.
    Journal of cardiovascular risk, 2002, Volume: 9, Issue:1

    Topics: Adult; Aged; Atorvastatin; Clofibric Acid; Drug Therapy, Combination; Female; Fibric Acids; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lipids; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrroles; Simvastatin; Time Factors

2002
Efficacy of atorvastatin and gemfibrozil, alone and in low dose combination, in the treatment of diabetic dyslipidemia.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:7

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Follow-Up Studies; Gemfibrozil; Heptanoic Acids; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Male; Middle Aged; Pyrroles; Treatment Outcome

2003
Predictors of change in low-density lipoprotein size during lipid-lowering treatment in type 2 diabetes.
    Metabolism: clinical and experimental, 2004, Volume: 53, Issue:11

    Topics: Aged; Anticholesteremic Agents; Apolipoproteins B; Atorvastatin; Cholesterol, HDL; Cholesterol, LDL; Cross-Over Studies; Diabetes Mellitus, Type 2; Female; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Pyrroles; Triglycerides

2004
Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites.
    Clinical pharmacology and therapeutics, 2005, Volume: 78, Issue:2

    Topics: Adult; Area Under Curve; Atorvastatin; Cross-Over Studies; Drug Interactions; Female; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Pyrroles; Rifampin

2005
A randomized trial of the effect of statin and fibrate therapy on arterial function in CKD.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2007, Volume: 49, Issue:6

    Topics: Adult; Aged; Atorvastatin; Brachial Artery; Double-Blind Method; Elasticity; Endothelium, Vascular; Female; Gemfibrozil; Glomerular Filtration Rate; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Insulin Resistance; Kidney Failure, Chronic; Male; Middle Aged; Pyrroles; Treatment Outcome

2007
Use of lipid-modulating drugs in complicated course of coronary heart disease.
    Bulletin of experimental biology and medicine, 2007, Volume: 144, Issue:3

    Topics: Antithrombin III; Atorvastatin; Cholesterol, LDL; Coronary Disease; Echocardiography; Female; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Peptide Hydrolases; Pravastatin; Prothrombin; Pyrroles; Simvastatin; von Willebrand Factor

2007
Effects of gemfibrozil and atorvastatin on the pharmacokinetics of repaglinide in relation to SLCO1B1 polymorphism.
    Clinical pharmacology and therapeutics, 2008, Volume: 84, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Atorvastatin; Blood Glucose; Carbamates; Cross-Over Studies; Drug Interactions; Female; Gemfibrozil; Genotype; Half-Life; Heptanoic Acids; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Liver-Specific Organic Anion Transporter 1; Male; Organic Anion Transporters; Piperidines; Polymorphism, Genetic; Pyrroles

2008
Effect of gemfibrozil and fenofibrate on the pharmacokinetics of atorvastatin.
    Journal of clinical pharmacology, 2011, Volume: 51, Issue:3

    Topics: Adult; Atorvastatin; Biotransformation; Cross-Over Studies; Drug Interactions; Enzyme Inhibitors; Female; Fenofibrate; Gemfibrozil; Half-Life; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Lactones; Male; Middle Aged; Pyrroles

2011

Other Studies

19 other study(ies) available for gemfibrozil and pyrroles

ArticleYear
Rhabdomyolysis after taking atorvastatin with gemfibrozil.
    The American journal of cardiology, 1998, Feb-01, Volume: 81, Issue:3

    Topics: Adult; Atorvastatin; Drug Interactions; Drug Therapy, Combination; Female; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hypertriglyceridemia; Hypolipidemic Agents; Pyrroles; Rhabdomyolysis

1998
Atorvastatin and gemfibrozil metabolites, but not the parent drugs, are potent antioxidants against lipoprotein oxidation.
    Atherosclerosis, 1998, Volume: 138, Issue:2

    Topics: Antioxidants; Atorvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hypolipidemic Agents; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Pyrroles

1998
Atorvastatin and gemfibrozil for protease-inhibitor-related lipid abnormalities.
    Lancet (London, England), 1998, Sep-26, Volume: 352, Issue:9133

    Topics: Anticholesteremic Agents; Atorvastatin; Drug Therapy, Combination; Gemfibrozil; Heptanoic Acids; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Protease Inhibitors; Pyrroles; Ritonavir; Saquinavir

1998
Long-term safety and efficacy of combination gemfibrozil and HMG-CoA reductase inhibitors for the treatment of mixed lipid disorders.
    American heart journal, 1999, Volume: 138, Issue:1 Pt 1

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Indoles; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrroles; Simvastatin; Time Factors; Treatment Outcome

1999
How to manage metabolic complications of HIV therapy: what to do while we wait for answers.
    The AIDS reader, 2000, Volume: 10, Issue:3

    Topics: Anabolic Agents; Anti-HIV Agents; Anticholesteremic Agents; Atorvastatin; Exercise Therapy; Gemfibrozil; Growth Hormone; Guidelines as Topic; Heptanoic Acids; HIV Infections; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Lipodystrophy; Metabolic Diseases; Metformin; Nucleosides; Protease Inhibitors; Pyrroles; Reverse Transcriptase Inhibitors; Risk Factors; Thiazoles; Thiazolidinediones

2000
Lipid modulation and atherosclerotic events: extending the clinical spectrum with fibrates and statins.
    Current atherosclerosis reports, 2000, Volume: 2, Issue:1

    Topics: Adult; Aged; Anticholesteremic Agents; Arteriosclerosis; Atorvastatin; Clinical Trials as Topic; Evidence-Based Medicine; Gemfibrozil; Heptanoic Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Middle Aged; Myocardial Revascularization; Preventive Medicine; Pyrroles

2000
Effects of fibrates on metabolism of statins in human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:11

    Topics: Aryl Hydrocarbon Hydroxylases; Atorvastatin; Cytochrome P-450 CYP2C8; Fenofibrate; Fluorobenzenes; Gemfibrozil; Glucuronosyltransferase; Hepatocytes; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; In Vitro Techniques; Microsomes, Liver; Oxidation-Reduction; Pyrimidines; Pyrroles; Rosuvastatin Calcium; Simvastatin; Sulfonamides

2002
Interaction between fibrates and statins--metabolic interactions with gemfibrozil.
    Drug metabolism and drug interactions, 2003, Volume: 19, Issue:3

    Topics: Atorvastatin; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Microsomes, Liver; Pyridines; Pyrroles; Quinolines

2003
Differential associations of statin and fibrate treatment with carotid arterial remodeling.
    American journal of hypertension, 2005, Volume: 18, Issue:11

    Topics: Adult; Atorvastatin; Bezafibrate; Body Mass Index; Carotid Arteries; Cholesterol, HDL; Clofibric Acid; Cohort Studies; Dyslipidemias; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fibric Acids; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Male; Middle Aged; Multivariate Analysis; Pravastatin; Pyridines; Pyrroles; Risk Factors; Simvastatin; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography

2005
Atorvastatin glucuronidation is minimally and nonselectively inhibited by the fibrates gemfibrozil, fenofibrate, and fenofibric acid.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:8

    Topics: Anticholesteremic Agents; Area Under Curve; Atorvastatin; Catalysis; Drug Interactions; Fenofibrate; Gemfibrozil; Glucuronic Acid; Glucuronides; Glucuronosyltransferase; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinetics; Lactones; Microsomes, Liver; Models, Biological; Molecular Structure; Pyrroles; Recombinant Proteins; Tandem Mass Spectrometry; Uridine Diphosphate Glucuronic Acid

2007
Efficacy of lipid-lowering medications in patients treated with clozapine: a naturalistic study.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:3

    Topics: Adult; Antipsychotic Agents; Atorvastatin; Cholesterol; Clozapine; Female; Fenofibrate; Gemfibrozil; Heptanoic Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pravastatin; Psychotic Disorders; Pyrroles; Retrospective Studies; Schizophrenia; Treatment Outcome; Triglycerides

2008
Familial dysbetalipoproteinemia: a potentially fatal disorder.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2008, Volume: 18, Issue:8

    Topics: Adolescent; Adult; Anticholesteremic Agents; Atorvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hyperlipoproteinemia Type III; Hypolipidemic Agents; Male; Pyrroles; Risk Factors

2008
Impact of chronic anticholesterol therapy on development of microvascular rarefaction in the metabolic syndrome.
    Microcirculation (New York, N.Y. : 1994), 2009, Volume: 16, Issue:8

    Topics: Animals; Anticholesteremic Agents; Arterioles; Atorvastatin; Cytokines; Gemfibrozil; Heptanoic Acids; Inflammation; Male; Metabolic Syndrome; Microcirculation; Muscle, Skeletal; Nitric Oxide; Probucol; Pyrroles; Rats; Rats, Zucker; Simvastatin; Time Factors

2009
Genotoxic effects in fish induced by pharmacological agents present in the sewage of some Italian water-treatment plants.
    Environmental toxicology, 2012, Volume: 27, Issue:1

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Comet Assay; DNA Damage; Environmental Monitoring; Gemfibrozil; Heptanoic Acids; Hypolipidemic Agents; Italy; Mutagens; Piperazines; Purines; Pyrroles; Random Amplified Polymorphic DNA Technique; Sewage; Sildenafil Citrate; Sulfones; Vasodilator Agents; Waste Disposal, Fluid; Water Pollutants, Chemical; Zebrafish

2012
Statins alter intracellular calcium homeostasis in malignant hyperthermia susceptible individuals.
    Cardiovascular therapeutics, 2010, Volume: 28, Issue:6

    Topics: Animals; Atorvastatin; Biopsy; Calcium; Electric Stimulation; Female; Gemfibrozil; Genotype; Heptanoic Acids; Homeostasis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Isometric Contraction; Male; Malignant Hyperthermia; Muscle, Skeletal; Phenotype; Pyrroles; Rhabdomyolysis; Simvastatin; Swine; Time Factors

2010
RLIP76, a glutathione-conjugate transporter, plays a major role in the pathogenesis of metabolic syndrome.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Animals; Antisense Elements (Genetics); Atorvastatin; Gemfibrozil; GTPase-Activating Proteins; Heptanoic Acids; Hypoglycemic Agents; Hypolipidemic Agents; Metabolic Syndrome; Metformin; Mice; Mice, Knockout; Pyrroles; Rosiglitazone; Thiazolidinediones

2011
Statin-associated polymyositis following omeprazole treatment.
    Clinical medicine & research, 2013, Volume: 11, Issue:2

    Topics: Anticholesteremic Agents; Atorvastatin; Drug Interactions; Esophagitis; Gemfibrozil; Heptanoic Acids; Humans; Male; Methotrexate; Middle Aged; Myocardial Infarction; Omeprazole; Polymyositis; Prednisone; Proton Pump Inhibitors; Pyrroles; Treatment Outcome; Withholding Treatment

2013
Comparative effectiveness of fish oil versus fenofibrate, gemfibrozil, and atorvastatin on lowering triglyceride levels among HIV-infected patients in routine clinical care.
    Journal of acquired immune deficiency syndromes (1999), 2013, Nov-01, Volume: 64, Issue:3

    Topics: Adult; Alabama; Atorvastatin; California; CD4-Positive T-Lymphocytes; Cohort Studies; Comparative Effectiveness Research; Drug Interactions; Female; Fenofibrate; Fish Oils; Gemfibrozil; Heptanoic Acids; HIV Infections; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Male; Middle Aged; North Carolina; Practice Guidelines as Topic; Pyrroles; Retrospective Studies; San Francisco; Treatment Outcome; Triglycerides; Washington

2013
Eicosapentaenoic acid inhibits glucose-induced membrane cholesterol crystalline domain formation through a potent antioxidant mechanism.
    Biochimica et biophysica acta, 2015, Volume: 1848, Issue:2

    Topics: Antioxidants; Atorvastatin; Cholesterol, LDL; Eicosapentaenoic Acid; Fenofibrate; Gemfibrozil; Glucose; Heptanoic Acids; Lipid Peroxidation; Lipid Peroxides; Membrane Lipids; Membranes, Artificial; Niacin; Pyrroles

2015