gemfibrozil and propofol

gemfibrozil has been researched along with propofol in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Galetin, A; Gill, KL; Houston, JB1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Burchell, B; Coffey, MJ; Findlay, KA; Riley, RJ; Soars, MG1
Kamimura, H; Mano, Y; Usui, T1

Reviews

1 review(s) available for gemfibrozil and propofol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

7 other study(ies) available for gemfibrozil and propofol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Characterization of in vitro glucuronidation clearance of a range of drugs in human kidney microsomes: comparison with liver and intestinal glucuronidation and impact of albumin.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:4

    Topics: Adult; Aged; Female; Glucuronides; Glucuronosyltransferase; Humans; In Vitro Techniques; Intestinal Mucosa; Intestines; Kidney; Liver; Male; Metabolic Clearance Rate; Microsomes; Middle Aged; Organ Specificity; Pharmaceutical Preparations; Predictive Value of Tests; Protein Binding; Serum Albumin, Bovine; Substrate Specificity; Young Adult

2012
Evidence for significant differences in microsomal drug glucuronidation by canine and human liver and kidney.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:2

    Topics: Adult; Androstane-3,17-diol; Animals; Dogs; Female; Furosemide; Gemfibrozil; Glucuronidase; Glucuronides; Humans; Ketoprofen; Kidney; Kinetics; Male; Microsomes; Microsomes, Liver; Middle Aged; Models, Animal; Propofol; Species Specificity

2001
The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
    Drug metabolism and disposition: the biological fate of chemicals, 2007, Volume: 35, Issue:11

    Topics: Catalysis; Enzyme Inhibitors; Estradiol; Flurbiprofen; Gemfibrozil; Glucuronosyltransferase; Glycosylation; Humans; Hypolipidemic Agents; Isoenzymes; Kinetics; Mefenamic Acid; Microsomes, Liver; Molecular Structure; Morphine; Propofol; Recombinant Proteins

2007