gemfibrozil and probucol

gemfibrozil has been researched along with probucol in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199020 (47.62)18.7374
1990's13 (30.95)18.2507
2000's4 (9.52)29.6817
2010's4 (9.52)24.3611
2020's1 (2.38)2.80

Authors

AuthorsStudies
Aizawa, Y; Fujita, T; Hasegawa, K; Horikoshi, H; Kanai, T; Kurumada, T; Yoshioka, T1
Topliss, JG; Yoshida, F1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
D'Amico, G; Gentile, MG1
Kłosiewicz-Latoszek, L; Szostak, WB1
Eisenberg, JM; Glick, H; Jacobson, TA; Kinosian, B; Koffer, H; Schulman, KA; Willian, MK1
Shapiro, DR; Walker, JF1
Hunninghake, DB2
Islami, Y; Ribeiro, LG1
Naito, HK1
Davignon, J1
Blum, CB; Levy, RI1
Nikkilä, EA; Tikkanen, MJ1
Perry, RS1
Havel, RJ; Kane, JP1
Malinow, MR1
Gotto, AM; Jones, PH; Scott, LW1
Levy, RI; Schaefer, EJ1
Santafé Oroz, J; Segarra Domènech, J1
Nash, DT2
Glueck, C1
Kuo, PT1
Ades, EW; Lawley, TJ; Pruckler, JM1
Boissonnat, P; de Lorgeril, M; Dureau, G; Monjaud, I; Salen, P1
Kesten, S; Maurer, J; Mayne, L; Scavuzzo, M1
Bays, HE; Dujovne, CA1
Mendonça, CX; Mori, AV; Santos, CO1
Ando, N; Ashidate, K; Kaneko, K; Kawamura, M; Miyazaki, S; Teramoto, T; Thoda, H1
Frisbee, JC; Frisbee, SJ; Goodwill, AG; James, ME; Stapleton, PA1
Chen, L; Chen, SC; Tsui, L; Wu, SJ; Xie, W; Xu, S; Ye, P1

Reviews

12 review(s) available for gemfibrozil and probucol

ArticleYear
Reducing high blood cholesterol level with drugs. Cost-effectiveness of pharmacologic management.
    JAMA, 1990, Dec-19, Volume: 264, Issue:23

    Topics: Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Colestipol; Cost-Benefit Analysis; Drug Therapy, Combination; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Niacin; Probucol; Sensitivity and Specificity

1990
Drug treatment of dyslipoproteinemia.
    Endocrinology and metabolism clinics of North America, 1990, Volume: 19, Issue:2

    Topics: Bile Acids and Salts; Clofibrate; Coronary Disease; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemias; Hypolipoproteinemias; Niacin; Probucol

1990
Lipid lowering effects on cardiovascular morbidity and mortality. Clinical evidence and therapeutic guidelines.
    Arquivos brasileiros de cardiologia, 1988, Volume: 51, Issue:1

    Topics: Cholesterol; Cholestyramine Resin; Clinical Trials as Topic; Clofibrate; Coronary Disease; Follow-Up Studies; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins; Male; Probucol; Triglycerides

1988
Reducing cardiac deaths with hypolipidemic drugs.
    Postgraduate medicine, 1987, Nov-01, Volume: 82, Issue:6

    Topics: Cholesterol; Cholestyramine Resin; Clofibrate; Colestipol; Coronary Disease; Feeding Behavior; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids; Lipoproteins, LDL; Niacin; Patient Education as Topic; Pentanoic Acids; Probucol

1987
Contemporary recommendations for evaluating and treating hyperlipidemia.
    Clinical pharmacy, 1986, Volume: 5, Issue:2

    Topics: Clofibrate; Dextrothyroxine; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids; Lipoproteins; Lovastatin; Naphthalenes; Neomycin; Niacin; Pentanoic Acids; Phenotype; Probucol

1986
Treatment of hypercholesterolemia.
    Annual review of medicine, 1986, Volume: 37

    Topics: Animals; Cholestyramine Resin; Clofibrate; Colestipol; Cricetinae; Dogs; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Mice; Middle Aged; Neomycin; Niacin; Pentanoic Acids; Pregnancy; Probucol; Rats

1986
The diagnosis and management of hyperlipidemia.
    Disease-a-month : DM, 1986, Volume: 32, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Cholesterol; Cholestyramine Resin; Chylomicrons; Clofibrate; Colestipol; Coronary Disease; Dextrothyroxine; Dietary Fats; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hyperlipidemias; Hyperlipoproteinemia Type I; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type III; Hyperlipoproteinemia Type IV; Hyperlipoproteinemia Type V; Lipoproteins; Lipoproteins, LDL; Neomycin; Niacin; Pentanoic Acids; Probucol; Receptors, LDL; Triglycerides

1986
Pathogenesis and management of lipoprotein disorders.
    The New England journal of medicine, 1985, May-16, Volume: 312, Issue:20

    Topics: Abetalipoproteinemia; Adolescent; Adult; Aged; Child; Child, Preschool; Cholestyramine Resin; Chylomicrons; Colestipol; Dietary Fats; Female; Gemfibrozil; Humans; Hyperlipoproteinemia Type I; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type III; Hyperlipoproteinemia Type IV; Hyperlipoproteinemia Type V; Hyperlipoproteinemias; Hypobetalipoproteinemias; Hypolipoproteinemias; Infant; Infant, Newborn; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Middle Aged; Niacin; Pentanoic Acids; Probucol; Tangier Disease

1985
[Pharmacologic therapy of atherosclerosis (I). Current possibilities].
    Medicina clinica, 1983, Nov-26, Volume: 81, Issue:17

    Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Clofibrate; Clofibric Acid; Fenofibrate; Gemfibrozil; Glycosaminoglycans; Humans; Ion Exchange Resins; Lipoproteins; Nicotinic Acids; Pentanoic Acids; Probucol

1983
Recommendations for treatment of hyperlipidemia in adults. A joint statement of the Nutrition Committee and the Council on Arteriosclerosis.
    Circulation, 1984, Volume: 69, Issue:5

    Topics: Cholesterol; Clofibrate; Coronary Disease; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type IV; Hyperlipoproteinemias; Lactation; Lipoproteins; Lovastatin; Naphthalenes; Niacin; Pentanoic Acids; Pregnancy; Pregnancy Complications; Probucol; Tangier Disease; Triglycerides

1984
Dyslipidemia and coronary artery disease.
    Clinical cardiology, 1994, Volume: 17, Issue:10

    Topics: Arteriosclerosis; Cholesterol; Coronary Disease; Drug Therapy, Combination; Exercise; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Niacin; Probucol

1994
Drug interactions of lipid-altering drugs.
    Drug safety, 1998, Volume: 19, Issue:5

    Topics: Contraindications; Drug Interactions; Fenofibrate; Fish Oils; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Niacin; Probucol; Resins, Plant

1998

Trials

3 trial(s) available for gemfibrozil and probucol

ArticleYear
Pharmacological and dietary treatment of lipid abnormalities in nephrotic patients.
    Kidney international. Supplement, 1991, Volume: 31

    Topics: Cholestyramine Resin; Colestipol; Food, Formulated; Gemfibrozil; Humans; Hyperlipidemias; Lipids; Lovastatin; Nephrotic Syndrome; Probucol

1991
Hydroxymethylglutaryl coenzyme A reductase inhibitors as monotherapy in the treatment of hypercholesterolemia.
    The American journal of cardiology, 1990, Mar-20, Volume: 65, Issue:12

    Topics: Bezafibrate; Cholestyramine Resin; Double-Blind Method; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Probucol; Randomized Controlled Trials as Topic; Simvastatin

1990
Lipid lowering effects on cardiovascular morbidity and mortality. Clinical evidence and therapeutic guidelines.
    Arquivos brasileiros de cardiologia, 1988, Volume: 51, Issue:1

    Topics: Cholesterol; Cholestyramine Resin; Clinical Trials as Topic; Clofibrate; Coronary Disease; Follow-Up Studies; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins; Male; Probucol; Triglycerides

1988

Other Studies

28 other study(ies) available for gemfibrozil and probucol

ArticleYear
Studies on hindered phenols and analogues. 1. Hypolipidemic and hypoglycemic agents with ability to inhibit lipid peroxidation.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:2

    Topics: Animals; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Phenols; Rats; Structure-Activity Relationship

1989
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Choice of cholesterol-lowering drugs.
    The Medical letter on drugs and therapeutics, 1991, Jan-11, Volume: 33, Issue:835

    Topics: Anticholesteremic Agents; Cholestyramine Resin; Clofibrate; Colestipol; Fish Oils; Gemfibrozil; Humans; Lovastatin; Neomycin; Niacin; Probucol

1991
Comparative studies on the influence of different fibrates on serum lipoproteins in endogenous hyperlipoproteinaemia.
    European journal of clinical pharmacology, 1991, Volume: 40, Issue:1

    Topics: Adult; Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Colestipol; Female; Fenofibrate; Gemfibrozil; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged; Probucol

1991
Current and new therapy for hypercholesterolemia.
    The Journal of the American Osteopathic Association, 1988, Volume: 88, Issue:7

    Topics: Anticholesteremic Agents; Colestipol; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Niacin; Probucol

1988
Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. The Expert Panel.
    Archives of internal medicine, 1988, Volume: 148, Issue:1

    Topics: Adult; Aged; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Colestipol; Coronary Disease; Dietary Fats; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl CoA Reductases; Hypercholesterolemia; Male; Middle Aged; Niacin; Patient Compliance; Pentanoic Acids; Probucol; Risk Factors

1988
Medical management of hyperlipidemia and the role of probucol.
    The American journal of cardiology, 1986, Jun-27, Volume: 57, Issue:16

    Topics: Adult; Arteriosclerosis; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Colestipol; Female; Gemfibrozil; Humans; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemias; Hypolipidemic Agents; Male; Middle Aged; Niacin; Pentanoic Acids; Phenols; Probucol; Risk

1986
Rational drug therapy of the hyperlipoproteinemias, Part II.
    Rational drug therapy, 1986, Volume: 20, Issue:10

    Topics: Cholestyramine Resin; Clofibrate; Colestipol; Dextrothyroxine; Female; Fish Oils; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemias; Hypolipidemic Agents; Male; Neomycin; Niacin; Pentanoic Acids; Probucol

1986
Current pharmacologic treatment of elevated serum cholesterol.
    Circulation, 1987, Volume: 76, Issue:3

    Topics: Adult; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Colestipol; Drug Tolerance; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Naphthalenes; Neomycin; Niacin; Pentanoic Acids; Probucol; Simvastatin; Triglycerides

1987
Adverse effects of the treatment for hyperlipidemia.
    Cardiology clinics, 1986, Volume: 4, Issue:1

    Topics: Anion Exchange Resins; Anticholesteremic Agents; Bibliographies as Topic; Clofibrate; Diet; Drug Therapy, Combination; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Neomycin; Niacin; Pentanoic Acids; Physical Exertion; Probucol; Risk

1986
Addition to labeling of cholestyramine.
    FDA drug bulletin, 1985, Volume: 15, Issue:1

    Topics: Cholestyramine Resin; Clofibrate; Diet Therapy; Drug Labeling; Gemfibrozil; Humans; Hypolipidemic Agents; Niacin; Pentanoic Acids; Probucol; Thyroxine; United States; United States Food and Drug Administration

1985
Lipid-lowering drugs.
    The Medical letter on drugs and therapeutics, 1985, Aug-30, Volume: 27, Issue:695

    Topics: Anticholesteremic Agents; Cholestyramine Resin; Clofibrate; Colestipol; Dextrothyroxine; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins; Neomycin; Niacin; Pentanoic Acids; Probucol; Triglycerides

1985
Gemfibrozil in combination with other drugs for severe hyperlipidemia. Preliminary study comprising four cases.
    Postgraduate medicine, 1983, Volume: 73, Issue:4

    Topics: Adult; Cholesterol; Cholestyramine Resin; Colestipol; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hyperlipidemias; Lipoproteins, HDL; Male; Middle Aged; Niacin; Pentanoic Acids; Probucol; Triglycerides; Valerates

1983
Influence of clofibrate, bile-sequestering agents and probucol on high-density lipoprotein levels.
    The American journal of cardiology, 1983, Aug-22, Volume: 52, Issue:4

    Topics: Bile Acids and Salts; Clofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins; Lipoproteins, HDL; Nicotinic Acids; Pentanoic Acids; Phenols; Probucol

1983
Hyperlipidemia: reducing the chances of cardiovascular disease.
    Geriatrics, 1984, Volume: 39, Issue:7

    Topics: Cholesterol; Cholestyramine Resin; Clofibrate; Coronary Disease; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Pentanoic Acids; Probucol; Triglycerides

1984
Use of a human microvascular endothelial cell line as a model system to evaluate cholesterol uptake.
    Pathobiology : journal of immunopathology, molecular and cellular biology, 1993, Volume: 61, Issue:5-6

    Topics: Biological Transport; Cells, Cultured; Cholesterol; Cholestyramine Resin; Clofibrate; Endothelium, Vascular; Gemfibrozil; Humans; Models, Biological; Probucol; Tritium

1993
Choice of cholesterol-lowering drugs.
    The Medical letter on drugs and therapeutics, 1993, Mar-05, Volume: 35, Issue:891

    Topics: Anticholesteremic Agents; Cholestyramine Resin; Clofibrate; Colestipol; Fish Oils; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Niacin; Probucol

1993
Fenofibrate, probucol, and other lipid-lowering treatments in heart transplant recipients.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1996, Volume: 15, Issue:5

    Topics: Anticholesteremic Agents; Cholestyramine Resin; Cyclosporine; Drug Interactions; Fenofibrate; Gemfibrozil; Heart Transplantation; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Lovastatin; Probucol; Simvastatin

1996
Lack of left ventricular dysfunction associated with sustained exposure to hyperlipidemia following lung transplantation.
    Chest, 1997, Volume: 112, Issue:4

    Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Cholestyramine Resin; Echocardiography; Female; Follow-Up Studies; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemias; Hypertriglyceridemia; Hypolipidemic Agents; Immunosuppressive Agents; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Lung Transplantation; Male; Middle Aged; Myocardial Ischemia; Probucol; Radionuclide Angiography; Retrospective Studies; Triglycerides; Ventricular Dysfunction, Left; Ventricular Function, Left

1997
Effect of dietary lipid-lowering drugs upon plasma lipids and egg yolk cholesterol levels of laying hens.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:11

    Topics: Animals; Anticholesteremic Agents; Chickens; Cholesterol; Dietary Supplements; Egg Yolk; Female; Gemfibrozil; Lipids; Lovastatin; Probucol; Triglycerides

1999
Gemfibrozil metabolite inhibits in vitro low-density lipoprotein (LDL) oxidation and diminishes cytotoxicity induced by oxidized LDL.
    Metabolism: clinical and experimental, 2000, Volume: 49, Issue:4

    Topics: Antioxidants; Azo Compounds; Cell Line; Cell Survival; Copper; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins, LDL; Macrophages; Nitriles; Oxidation-Reduction; Pentanoic Acids; Phenols; Probucol

2000
Impact of chronic anticholesterol therapy on development of microvascular rarefaction in the metabolic syndrome.
    Microcirculation (New York, N.Y. : 1994), 2009, Volume: 16, Issue:8

    Topics: Animals; Anticholesteremic Agents; Arterioles; Atorvastatin; Cytokines; Gemfibrozil; Heptanoic Acids; Inflammation; Male; Metabolic Syndrome; Microcirculation; Muscle, Skeletal; Nitric Oxide; Probucol; Pyrroles; Rats; Rats, Zucker; Simvastatin; Time Factors

2009
Adverse drug reactions of non-statin antihyperlipidaemic drugs in China from 1989 to 2019: a national database analysis.
    BMJ open, 2023, 05-30, Volume: 13, Issue:5

    Topics: Cholestyramine Resin; Drug-Related Side Effects and Adverse Reactions; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Niacin; Probucol

2023