gemfibrozil and nateglinide

gemfibrozil has been researched along with nateglinide in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Backman, JT; Juntti-Patinen, L; Neuvonen, M; Neuvonen, PJ; Niemi, M1
Izumi, S; Komori, T; Kusuhara, H; Maeda, K; Nozaki, Y; Sugiyama, Y; Takenaka, O1

Reviews

1 review(s) available for gemfibrozil and nateglinide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for gemfibrozil and nateglinide

ArticleYear
Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide.
    British journal of clinical pharmacology, 2005, Volume: 60, Issue:2

    Topics: Administration, Oral; Adult; Antifungal Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Blood Glucose; Cross-Over Studies; Cyclohexanes; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Female; Gemfibrozil; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Itraconazole; Male; Nateglinide; Phenylalanine

2005

Other Studies

2 other study(ies) available for gemfibrozil and nateglinide

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Investigation of the impact of substrate selection on in vitro organic anion transporting polypeptide 1B1 inhibition profiles for the prediction of drug-drug interactions.
    Drug metabolism and disposition: the biological fate of chemicals, 2015, Volume: 43, Issue:2

    Topics: Antihypertensive Agents; Binding, Competitive; Biological Transport; Cyclohexanes; Cyclosporine; Drug Evaluation, Preclinical; Drug Interactions; Estradiol; Gemfibrozil; HEK293 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Kinetics; Liver-Specific Organic Anion Transporter 1; Membrane Transport Modulators; Models, Biological; Nateglinide; Organic Anion Transporters; Phenylalanine; Recombinant Proteins; Rifampin; Sulfonamides; Torsemide

2015