gemfibrozil and naproxen

gemfibrozil has been researched along with naproxen in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (25.00)29.6817
2010's20 (71.43)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Ekins, S; Williams, AJ; Xu, JJ1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Darvesh, AS; Geldenhuys, WJ; Leeper, TC; Morris, DL; Sullivan, PG; Yonutas, HM1
Khan, AI; Lei, L; Norquist, AJ; O'Hare, D1
Lin, AY; Reinhard, M1
Balchen, M; Gjelstad, A; Pedersen-Bjergaard, S; Rasmussen, KE1
Nogueira, JM; Portugal, FC; Silva, AR1
Asami, M; Fujiwara, J; Kunikane, S; Manabe, S; Matsuda, M; Simazaki, D1
Alonso, E; Aparicio, I; Camacho-Muñoz, D; Martín, J; Santos, JL1
Gunsch, CK; Wang, S1
Bragg, LM; Dixon, G; Oakes, KD; Pawliszyn, J; Servos, MR; Wang, S1
Dickenson, ER; Drewes, JE; Hoppe-Jones, C1
Gagnon, GA; Krkošek, WH; Payne, SJ1
Ademollo, N; Barra Caracciolo, A; Di Lenola, M; Grenni, P; Patrolecco, L1
Ademollo, N; Capri, S; Patrolecco, L1
Alidina, M; Drewes, JE; Shewchuk, J1
Melvin, SD1
Carvalho, AJP; Dordio, AV; Miranda, S; Prates Ramalho, JP1
Groza, LG; Hebig, KH; Ptacek, CJ; Sabourin, MJ; Scheytt, TJ1
Bila, DM; da Fonseca, EM; da Silva de Freitas, A; de Oliveira Santos, AD; do Nascimento, MTL; Dos Santos, RF; Felix, LC; Hauser-Davis, RA; Neto, JAB; Sanson, AL1

Reviews

1 review(s) available for gemfibrozil and naproxen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

27 other study(ies) available for gemfibrozil and naproxen

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Identification of small molecules that bind to the mitochondrial protein mitoNEET.
    Bioorganic & medicinal chemistry letters, 2016, 11-01, Volume: 26, Issue:21

    Topics: Hypoglycemic Agents; Ligands; Mitochondrial Proteins; Protein Binding; Small Molecule Libraries; Thiazolidinediones

2016
Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
    Chemical communications (Cambridge, England), 2001, Nov-21, Issue:22

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Gemfibrozil; Hydrogen-Ion Concentration; Hydroxides; Ibuprofen; Naproxen; ortho-Aminobenzoates; Phenylacetates; Valproic Acid

2001
Photodegradation of common environmental pharmaceuticals and estrogens in river water.
    Environmental toxicology and chemistry, 2005, Volume: 24, Issue:6

    Topics: Chromatography, High Pressure Liquid; Environmental Monitoring; Estrogens; Gemfibrozil; Half-Life; Ibuprofen; Ketoprofen; Naproxen; Oxygen; Pharmaceutical Preparations; Photolysis; Propranolol; Rivers; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical

2005
Electrokinetic migration of acidic drugs across a supported liquid membrane.
    Journal of chromatography. A, 2007, Jun-08, Volume: 1152, Issue:1-2

    Topics: Acids; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Flurbiprofen; Gemfibrozil; Heptanol; Hydrogen-Ion Concentration; Ketoprofen; Membranes, Artificial; Naproxen; Pharmaceutical Preparations; Probenecid; Reproducibility of Results; Warfarin

2007
Advances in stir bar sorptive extraction for the determination of acidic pharmaceuticals in environmental water matrices Comparison between polyurethane and polydimethylsiloxane polymeric phases.
    Journal of chromatography. A, 2008, Oct-31, Volume: 1209, Issue:1-2

    Topics: Chromatography, High Pressure Liquid; Diclofenac; Dimethylpolysiloxanes; Gemfibrozil; Ibuprofen; Mefenamic Acid; Naproxen; Polyurethanes; Reproducibility of Results; Water Pollutants, Chemical; Water Purification

2008
Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2008, Volume: 58, Issue:5

    Topics: Antipyrine; Charcoal; Clofibric Acid; Diclofenac; Fenoprofen; Gemfibrozil; Halogenation; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Water Pollutants, Chemical; Water Purification; Water Supply

2008
Occurrence, temporal evolution and risk assessment of pharmaceutically active compounds in Doñana Park (Spain).
    Journal of hazardous materials, 2010, Nov-15, Volume: 183, Issue:1-3

    Topics: Environmental Monitoring; Estrogens; Fresh Water; Gemfibrozil; Ibuprofen; Industrial Waste; Naproxen; Pharmaceutical Preparations; Propranolol; Risk Assessment; Rivers; Seasons; Spain; Time Factors

2010
Effects of selected pharmaceutically active compounds on treatment performance in sequencing batch reactors mimicking wastewater treatment plants operations.
    Water research, 2011, Volume: 45, Issue:11

    Topics: Bacteria; Biodiversity; Bioreactors; Carbamazepine; Drug-Related Side Effects and Adverse Reactions; Gemfibrozil; Ketoprofen; Microbial Consortia; Naproxen; Pharmaceutical Preparations; Waste Disposal, Fluid; Water Microbiology; Water Pollutants, Chemical

2011
Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.
    Chemosphere, 2011, Volume: 85, Issue:9

    Topics: Animals; Atrazine; Benzhydryl Compounds; Carbamazepine; Diclofenac; Environmental Monitoring; Fishes; Fluoxetine; Gemfibrozil; Ibuprofen; Naproxen; Phenols; Solid Phase Extraction; Solid Phase Microextraction; Waste Disposal, Fluid; Water Pollutants, Chemical

2011
The role of microbial adaptation and biodegradable dissolved organic carbon on the attenuation of trace organic chemicals during groundwater recharge.
    The Science of the total environment, 2012, Oct-15, Volume: 437

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Adaptation, Physiological; Biodegradation, Environmental; Carbon; Clofibric Acid; Gemfibrozil; Groundwater; Ibuprofen; Ketoprofen; Naproxen; Organic Chemicals; Soil Microbiology; Water Microbiology; Water Pollutants, Chemical; Water Purification

2012
Removal of acidic pharmaceuticals within a nitrifying recirculating biofilter.
    Journal of hazardous materials, 2014, May-30, Volume: 273

    Topics: Adsorption; Bacteria; Biofilms; Diclofenac; DNA, Bacterial; Filtration; Gemfibrozil; Genes, Bacterial; Ibuprofen; Naproxen; Nitrification; Waste Disposal, Fluid; Water Pollutants, Chemical

2014
Capability of the natural microbial community in a river water ecosystem to degrade the drug naproxen.
    Environmental science and pollution research international, 2014, Volume: 21, Issue:23

    Topics: Ecosystem; Gemfibrozil; In Situ Hybridization, Fluorescence; Italy; Microbial Consortia; Naproxen; Rivers; Seasons; Water Pollutants, Chemical

2014
Occurrence of selected pharmaceuticals in the principal sewage treatment plants in Rome (Italy) and in the receiving surface waters.
    Environmental science and pollution research international, 2015, Volume: 22, Issue:8

    Topics: Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Estrone; Gemfibrozil; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Rome; Seasons; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical

2015
Effect of temperature on removal of trace organic chemicals in managed aquifer recharge systems.
    Chemosphere, 2015, Volume: 122

    Topics: Benzophenones; Diclofenac; Gemfibrozil; Groundwater; Ketoprofen; Naproxen; Soil Microbiology; Temperature; Trimethoprim; Water Pollutants, Chemical

2015
Oxidative stress, energy storage, and swimming performance of Limnodynastes peronii tadpoles exposed to a sub-lethal pharmaceutical mixture throughout development.
    Chemosphere, 2016, Volume: 150

    Topics: Animals; Anura; Atenolol; Australia; Behavior, Animal; Female; Gemfibrozil; Larva; Male; Naproxen; Oxidative Stress; Swimming

2016
Mechanisms of removal of three widespread pharmaceuticals by two clay materials.
    Journal of hazardous materials, 2017, Feb-05, Volume: 323, Issue:Pt A

    Topics: Adsorption; Aluminum Silicates; Clay; Computer Simulation; Drug Residues; Gemfibrozil; Kinetics; Mefenamic Acid; Models, Molecular; Naproxen; Particle Size; Pharmaceutical Preparations; Thermodynamics; Waste Disposal, Fluid

2017
Transport behavior of the pharmaceutical compounds carbamazepine, sulfamethoxazole, gemfibrozil, ibuprofen, and naproxen, and the lifestyle drug caffeine, in saturated laboratory columns.
    The Science of the total environment, 2017, Jul-15, Volume: 590-591

    Topics: Caffeine; Carbamazepine; Filtration; Gemfibrozil; Ibuprofen; Naproxen; Ontario; Silicon Dioxide; Sulfamethoxazole; Water Pollutants, Chemical

2017
Pharmaceuticals, natural and synthetic hormones and phenols in sediments from an eutrophic estuary, Jurujuba Sound, Guanabara Bay, Brazil.
    Marine pollution bulletin, 2022, Volume: 184

    Topics: Bays; Brazil; Diclofenac; Endocrine Disruptors; Environmental Monitoring; Estradiol; Estriol; Estrogens; Estrone; Estuaries; Gemfibrozil; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenols; Water Pollutants, Chemical

2022