gemfibrozil and lovastatin

gemfibrozil has been researched along with lovastatin in 127 studies

Research

Studies (127)

TimeframeStudies, this research(%)All Research%
pre-199014 (11.02)18.7374
1990's88 (69.29)18.2507
2000's16 (12.60)29.6817
2010's9 (7.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afonso, A; Burnett, DA; Clader, JW; Davis, HR; Huynh, T; Rosenblum, SB; Yumibe, N1
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Eichinger, M; Feussner, G; Ziegler, R1
McIntyre, TH; Shapiro, ML; Whitney, EJ; Wirebaugh, SR1
Belzer, FO; D'Alessandro, AM; Kalayoglu, M; Knechtle, SJ; Pirsch, JD; Reed, A; Sollinger, HW1
Barnett, MD; McKenney, JM; Proctor, JP; Wright, JT1
Chucrallah, A; De Girolami, U; Federman, M; Freeman, R1
Foo, WM; Lim, MC1
Tikkanen, MJ; Tilly-Kiesi, M2
Glueck, CJ; Lang, J; Oakes, N; Speirs, J; Tracy, T1
D'Agostino, LC; D'Agostino, RB; Kannel, WB; Stepanians, MN1
Neuman, HR; Neuman, J; Neuman, MP1
Aguirre, C; Anglada, J; Anguita, M; Azanza, JR; Barcina, C; Fabiani, F; Plaza, L; Soriguer, F; Vallés, F1
Batlouni, M; Bertolami, MC; Bismarck, ZF; Faludi, AA; Martinez, TL; Melo, RS; Pinto, LE1
Bernardi, G; Gavelli, MS; Rossi, FG; Santini, G; Serra, T; Vitaliano, E1
Colley, C; Lucas, LM; Magarian, GJ1
Jensen, K1
Helve, E; Ojala, JP; Tikkanen, MJ2
D'Amico, G; Gentile, MG1
Gross, KF; London, SF; Ringel, SP1
Garcia, RC; Nakandakare, E; Oliveira, HC; Quintão, EC; Rocha, JC; Sperotto, G1
Eisenberg, JM; Glick, H; Jacobson, TA; Kinosian, B; Koffer, H; Schulman, KA; Willian, MK1
Shapiro, DR; Walker, JF1
Goldberg, R; La Belle, P; Ronca, P; Zupkis, R1
Grundy, SM; Vega, GL5
Connor, WE1
Bentivoglio, M; Berioli, S; Conti, R; Corea, L; Osanna, RA; Savino, K; Zollino, L1
Larson, KK; Marais, GE1
Carlson, LA1
Glueck, CJ; Speirs, J; Tracy, T1
Gross, TP; Pierce, LR; Wysowski, DK1
Kogan, AD; Orenstein, S1
Bacon, S; Illingworth, DR1
Bocanegra, TS; Cook, T; Tikkanen, MJ; Walker, JF1
Garg, A; Grundy, SM1
Fishman, AB; Goldman, JA; Johnson, RJ; Lee, JE1
Helve, E; Jäättelä, A; Kaarsalo, E; Lehtonen, A; Malbecq, W; Oksa, H; Pääkkönen, P; Salmi, J; Tikkanen, MJ; Veharanta, T1
East, C; Grundy, SM; Vega, GL1
Mölgaard, J; Olsson, AG1
Hunninghake, DB1
Bilheimer, DW; East, C; Grundy, SM1
Nikkilä, EA; Tikkanen, MJ1
Perry, RS1
Maxwell, RE; Nawrocki, JW; Uhlendorf, PD1
Tobert, JA2
Ahmad, S1
Benson, VV; Borok, GM; Dudl, RJ; Epstein, A; Epstein, RS; Heys, JF; Menzin, J; Oster, G; Quinn, V1
Alaupovic, P; Dudley, VS; Knight-Gibson, C; Lane, DM; Laughlin, LO1
Chamone, D; da Luz, P; Mansur, AP; Maranhão, R; Pileggi, F; Ramires, JA; Solimene, MC1
Castro Cabezas, M; De Bruin, TW; Erkelens, DW; Kock, LA1
Bredie, SJ; de Bruin, TW; Demacker, PN; Kastelein, JJ; Stalenhoef, AF1
Johansson, J; Lithell, H; Ohrvall, M; Vessby, B1
Bays, H; Lansing, AM1
de Alava, E; Lozano, MD; Pardo-Mindán, FJ; Sola, JJ1
Lu, ZL1
Branchi, A; Fasoli, A; Gugliandolo, AG; Rovellini, A; Sommariva, D1
Ciafone, R; Galen, M; Knoll, RW1
Ooi, TC; Simo, IE; Yakichuk, JA1
Baigts, F; Devulder, B; Lecerf, JM; Luc, G1
Cramb, R; Head, A; Jakeman, PM; Kendall, MJ; Maxwell, S1
Rosenson, RS2
Hunninghake, DB; Knutson, KR; Kubo, SH; Olivari, MT; Peters, JR1
Abdul-Ghaffar, NU; el-Sonbaty, MR1
Baigts, F; Bruckert, E; De Gennes, JL; Malbecq, W1
Illingworth, R1
Boissonnat, P; de Lorgeril, M; Dureau, G; Monjaud, I; Salen, P1
Aranda, JL; del Palacio, A; Jover, E; Nogués, X; Rubiés-Prat, J1
Coulter, DM1
Chiari, A; Ghiselli, G; Giorgini, L; Lovisolo, PP; Musanti, R; Pirillo, A1
Bredie, SJ; de Bruin, TW; Kastelein, JJ; Knipscheer, HC; Stalenhoef, AF; Westerveld, HT1
Akçiçek, F; Alev, M; Atabay, G; Basçi, A; Duman, S; Kürsad, S; Ok, E; Unsal, A1
Glueck, CJ; Lang, JE; Wang, P1
Aumont, MC; Seknadji, P1
Bambauer, R; Müller, UA; Schiel, R1
Du Buf-Vereijken, PW; Spooren, PF; van Doormaal, JJ; van Puijenbroek, EP1
Autier, P; Muls, E; Van Gaal, L; Vansant, G1
Haffner, SM1
Barter, P; Clifton, P; Colquhoun, D; Hamilton-Craig, I; Nestel, P; Sikaris, K; Simons, L; Sullivan, D1
Isley, W; Rajeshawari, M; Tal, A1
Athyros, VG; Carina, MV; Didangelos, TP; Hatzikonstandinou, HA; Kontopoulos, AG; Kranitsas, DF; Papageorgiou, AA1
Kesten, S; Maurer, J; Mayne, L; Scavuzzo, M1
Chamone, D; da Luz, PL; Mansur, AP; Pileggi, F; Ramires, JA; Solimene, MC; Spósito, AC1
Adzet, T; Hernández, Y; Laguna, JC; Merlos, M; Ros, E; Vázquez, M; Zambón, D1
Ballesta, AM; Casals, E; Ojuel, J; Rodriguez-Villar, C; Ros, E; Sanllehy, C; Zambón, D1
Bergö, M; Bond, BC; Gribble, AD; Groot, PH; Havekes, LM; Hofker, MH; Pearce, NJ; Staels, B; van Vlijmen, BJ; Yates, JW1
Sinzinger, H1
Casals, E; Hernández, G; Laguna, JC; Rodriguez-Villar, C; Ros, E; Sanllehy, C; Sol, JM; Vázquez, M; Zambón, D1
Fuh, MM; Hung, YJ; Jeng, C; Kuo, SW; Pei, D; Wu, DA1
Haffner, SM; Rader, DJ1
Frane, AM; Gantner, SE; Joyce, DM; Kersten, ME; Murdock, AK; Murdock, DK; Murdock, RW; Olson, KJ1
Freeman, NJ; Landesman, KA; Stozek, M1
Mendonça, CX; Mori, AV; Santos, CO1
Black, DM1
Harangi, M; Paragh, G1
Backman, JT; Kivistö, KT; Kyrklund, C; Laitila, J; Neuvonen, M; Neuvonen, PJ1
Sprecher, DL1
Pearson, TA1
Mikhailidis, DP; Milionis, HJ; Rizos, E1
Platts, J1
Bouzamondo, A; Corvol, JC; Hulot, JS; Lechat, P; Sanchez, P; Sirol, M1
Barberá, G; Chacón, P; Hernández, C; Lecube, A; Lima, J; Simó, R1
Boden, WE1
Dellavalle, RP; Drake, AL; Freeman, SR; Graber, M; Heilig, LF; McNealy, K; Schilling, LM1
Dimitri, E; Landry, P; Légaré, N; Tessier, S1
Fan, J; Jiang, L; Kong, X; Li, Z; Wu, T; Yuan, H1
Akai, S; Matsubara, A; Oda, S; Watanabe, K; Yokoi, T1

Reviews

20 review(s) available for gemfibrozil and lovastatin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Hyperlipidemia and transplantation: etiologic factors and therapy.
    Journal of the American Society of Nephrology : JASN, 1992, Volume: 2, Issue:12 Suppl

    Topics: Adrenal Cortex Hormones; Antihypertensive Agents; Coronary Disease; Diuretics; Gemfibrozil; Humans; Hyperlipidemias; Immunosuppressive Agents; Kidney Failure, Chronic; Kidney Transplantation; Lipid Metabolism; Lipoprotein Lipase; Lovastatin; Postoperative Complications; Risk Factors

1992
Gemfibrozil-induced myopathy.
    Archives of internal medicine, 1991, Volume: 151, Issue:9

    Topics: Clofibrate; Drug Therapy, Combination; Gemfibrozil; Humans; Hypertriglyceridemia; Lovastatin; Male; Middle Aged; Muscular Diseases

1991
Reducing high blood cholesterol level with drugs. Cost-effectiveness of pharmacologic management.
    JAMA, 1990, Dec-19, Volume: 264, Issue:23

    Topics: Anticholesteremic Agents; Cholestyramine Resin; Clinical Trials as Topic; Colestipol; Cost-Benefit Analysis; Drug Therapy, Combination; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Niacin; Probucol; Sensitivity and Specificity

1990
Contemporary recommendations for evaluating and treating hyperlipidemia.
    Clinical pharmacy, 1986, Volume: 5, Issue:2

    Topics: Clofibrate; Dextrothyroxine; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids; Lipoproteins; Lovastatin; Naphthalenes; Neomycin; Niacin; Pentanoic Acids; Phenotype; Probucol

1986
Recommendations for treatment of hyperlipidemia in adults. A joint statement of the Nutrition Committee and the Council on Arteriosclerosis.
    Circulation, 1984, Volume: 69, Issue:5

    Topics: Cholesterol; Clofibrate; Coronary Disease; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type IV; Hyperlipoproteinemias; Lactation; Lipoproteins; Lovastatin; Naphthalenes; Niacin; Pentanoic Acids; Pregnancy; Pregnancy Complications; Probucol; Tangier Disease; Triglycerides

1984
[Secondary prevention after myocardial infarction; rôle of platelet antiaggregants and hypolipemic agents].
    Archives des maladies du coeur et des vaisseaux, 1996, Volume: 89 Spec No 3

    Topics: Anticholesteremic Agents; Aspirin; Coronary Disease; Cost-Benefit Analysis; Gemfibrozil; Humans; Hypolipidemic Agents; Lovastatin; Myocardial Infarction; Platelet Aggregation Inhibitors; Risk Factors; Simvastatin

1996
Effect of statins on metabolism of apo-B-containing lipoproteins in hypertriglyceridemic men.
    The American journal of cardiology, 1998, Feb-26, Volume: 81, Issue:4A

    Topics: Apolipoproteins B; Cholesterol, LDL; Cholesterol, VLDL; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Hypolipidemic Agents; Insulin Resistance; Lipoproteins; Lipoproteins, IDL; Lipoproteins, LDL; Lovastatin; Male; Niacin

1998
[Antilipemic agents and atherothrombosis. Effects of antilipemic agents on blood platelet function, coagulation and fibrinolysis].
    Deutsche medizinische Wochenschrift (1946), 1998, Sep-18, Volume: 123, Issue:38

    Topics: Anticholesteremic Agents; Antiporters; Arteriosclerosis; Bezafibrate; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Clinical Trials as Topic; Clofibric Acid; Fenofibrate; Fibrinolysis; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Niacin; Pravastatin; Risk Factors; Simvastatin; Thrombosis

1998
Role of fibrates in the management of hypertriglyceridemia.
    The American journal of cardiology, 1999, May-13, Volume: 83, Issue:9B

    Topics: Anticholesteremic Agents; Cardiovascular Diseases; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Hypolipidemic Agents; Lovastatin; Male; Randomized Controlled Trials as Topic; Risk Factors

1999
Statins in children: what do we know and what do we need to do?
    Current atherosclerosis reports, 2001, Volume: 3, Issue:1

    Topics: Atorvastatin; Bezafibrate; Child; Child Welfare; Cost-Benefit Analysis; Drug Approval; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Pyridines; Pyrroles; Simvastatin

2001
[The role of HDL in the prevention of cardiovascular events].
    Orvosi hetilap, 2001, Jan-21, Volume: 142, Issue:3

    Topics: Anticholesteremic Agents; Arteriosclerosis; Aryldialkylphosphatase; Atorvastatin; Cholesterol, HDL; Esterases; Fatty Acids, Monounsaturated; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Lipid Peroxidation; Lovastatin; Phosphatidylcholine-Sterol O-Acyltransferase; Pyrroles; Simvastatin

2001
Raising high-density lipoprotein cholesterol with niacin and fibrates: a comparative review.
    The American journal of cardiology, 2000, Dec-21, Volume: 86, Issue:12A

    Topics: Cholesterol, HDL; Clinical Trials as Topic; Coronary Disease; Drug Combinations; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Male; Myocardial Infarction; Niacin; Ultrasonography

2000
Divergent approaches to the treatment of dyslipidemia with low levels of high-density lipoprotein cholesterol.
    The American journal of cardiology, 2000, Dec-21, Volume: 86, Issue:12A

    Topics: Cholesterol, HDL; Clinical Trials as Topic; Drug Combinations; Ethanol; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Life Style; Lovastatin; Niacin

2000
Smoking diminishes the beneficial effect of statins: observations from the landmark trials.
    Angiology, 2001, Volume: 52, Issue:9

    Topics: Anticholesteremic Agents; Clinical Trials as Topic; Gemfibrozil; Humans; Lovastatin; Myocardial Ischemia; Pravastatin; Risk Factors; Simvastatin; Smoking

2001
Differential effects of lipid-lowering therapies on stroke prevention: a meta-analysis of randomized trials.
    Archives of internal medicine, 2003, Mar-24, Volume: 163, Issue:6

    Topics: Anticholesteremic Agents; Atorvastatin; Cholestyramine Resin; Clofibrate; Colestipol; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Myocardial Infarction; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Regression Analysis; Risk Assessment; Risk Factors; Simvastatin; Stroke; Treatment Failure; Treatment Outcome

2003
Therapeutic implications of recent ATP III guidelines and the important role of combination therapy in total dyslipidemia management.
    Current opinion in cardiology, 2003, Volume: 18, Issue:4

    Topics: Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Diabetic Angiopathies; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Metabolic Syndrome; Practice Guidelines as Topic

2003
Low high-density lipoprotein cholesterol disorders and cardiovascular risk: contribution of associated low-density lipoprotein subclass abnormalities.
    Current opinion in cardiology, 2005, Volume: 20, Issue:4

    Topics: Atherosclerosis; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins, LDL; Lovastatin; Risk Factors; Simvastatin

2005
Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.
    Journal of the National Cancer Institute, 2006, Nov-01, Volume: 98, Issue:21

    Topics: Atorvastatin; Bezafibrate; Clofibrate; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Incidence; Lovastatin; Melanoma; Odds Ratio; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Reproducibility of Results; Simvastatin; Skin Neoplasms; United States

2006
Lipid-lowering agents for nephrotic syndrome.
    The Cochrane database of systematic reviews, 2013, Dec-10, Issue:12

    Topics: Adult; Child; Fatty Acids, Monounsaturated; Fluvastatin; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Lovastatin; Nephrotic Syndrome; Randomized Controlled Trials as Topic; Simvastatin

2013

Trials

42 trial(s) available for gemfibrozil and lovastatin

ArticleYear
The influence of simvastatin alone or in combination with gemfibrozil on plasma lipids and lipoproteins in patients with type III hyperlipoproteinemia.
    The Clinical investigator, 1992, Volume: 70, Issue:11

    Topics: Adult; Apolipoprotein E2; Apolipoproteins E; Cholesterol; Cholesterol, LDL; Combined Modality Therapy; Dietary Fats; Double-Blind Method; Female; Gemfibrozil; Humans; Hyperlipoproteinemia Type III; Hyperlipoproteinemias; Lipids; Lipoproteins; Lipoproteins, VLDL; Lovastatin; Male; Simvastatin; Triglycerides

1992
Comparison of gemfibrozil and lovastatin in patients with high low-density lipoprotein and low high-density lipoprotein cholesterol levels.
    Archives of internal medicine, 1992, Volume: 152, Issue:9

    Topics: Cholesterol, Dietary; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged

1992
A comparison between lovastatin and gemfibrozil in the treatment of primary hypercholesterolemia.
    The American journal of cardiology, 1992, Jan-01, Volume: 69, Issue:1

    Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Multivariate Analysis; Research Design; Triglycerides

1992
Significant increase of high-density lipoprotein2-cholesterol under prolonged simvastatin treatment.
    Atherosclerosis, 1991, Volume: 91 Suppl

    Topics: Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1991
A multicenter double-blind study comparing lovastatin and gemfibrozil in the treatment of primary hypercholesterolemia.
    Atherosclerosis, 1991, Volume: 91 Suppl

    Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Triglycerides

1991
[Comparison between lovastatin and gemfibrozil in treatment of primary hyperlipidemias].
    Arquivos brasileiros de cardiologia, 1991, Volume: 56, Issue:5

    Topics: Adult; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypertriglyceridemia; Lovastatin; Male; Middle Aged; Triglycerides

1991
[Therapy of hypercholesterolemia and hypertriglyceridemia. Comparison of hypolipemic effects of lovastatin and gemfibrozil].
    La Clinica terapeutica, 1991, Jan-15, Volume: 136, Issue:1

    Topics: Aged; Apolipoproteins B; Cholesterol; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Phospholipids; Triglycerides

1991
Pharmacological and dietary treatment of lipid abnormalities in nephrotic patients.
    Kidney international. Supplement, 1991, Volume: 31

    Topics: Cholestyramine Resin; Colestipol; Food, Formulated; Gemfibrozil; Humans; Hyperlipidemias; Lipids; Lovastatin; Nephrotic Syndrome; Probucol

1991
Treatment of combined hyperlipidemia with lovastatin versus gemfibrozil: a comparison study.
    Cardiology, 1990, Volume: 77 Suppl 4

    Topics: Apolipoproteins B; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Lovastatin; Male; Middle Aged; Triglycerides

1990
Effects of simvastatin, bezafibrate and gemfibrozil on the quantity and composition of plasma lipoproteins.
    Atherosclerosis, 1990, Volume: 85, Issue:2-3

    Topics: Adult; Aged; Apolipoproteins; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl CoA Reductases; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin

1990
Hydroxymethylglutaryl coenzyme A reductase inhibitors as monotherapy in the treatment of hypercholesterolemia.
    The American journal of cardiology, 1990, Mar-20, Volume: 65, Issue:12

    Topics: Bezafibrate; Cholestyramine Resin; Double-Blind Method; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Probucol; Randomized Controlled Trials as Topic; Simvastatin

1990
Comparison of the effects of lovastatin and gemfibrozil on lipids and glucose control in non-insulin-dependent diabetes mellitus.
    The American journal of cardiology, 1990, Sep-18, Volume: 66, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Randomized Controlled Trials as Topic; Triglycerides

1990
Primary hypertriglyceridemia with borderline high cholesterol and elevated apolipoprotein B concentrations. Comparison of gemfibrozil vs lovastatin therapy.
    JAMA, 1990, Dec-05, Volume: 264, Issue:21

    Topics: Adult; Aged; Apolipoproteins B; Cholesterol; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged

1990
[Simvastatin versus gemfibrozil in the treatment of primary hypercholesterolemia in hypertensive patients treated with hydrochlorothiazide].
    Cardiologia (Rome, Italy), 1990, Volume: 35, Issue:4

    Topics: Adult; Aged; Anticholesteremic Agents; Cholesterol; Female; Gemfibrozil; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1990
Management of primary mixed hyperlipidemia with lovastatin.
    Archives of internal medicine, 1990, Volume: 150, Issue:6

    Topics: Adult; Aged; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Drug Therapy, Combination; Gemfibrozil; Humans; Hyperlipidemias; Lovastatin; Male; Middle Aged; Triglycerides

1990
Influence of lovastatin plus gemfibrozil on plasma lipids and lipoproteins in patients with heterozygous familial hypercholesterolemia.
    Circulation, 1989, Volume: 79, Issue:3

    Topics: Adult; Cholesterol, HDL; Cholesterol, LDL; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gemfibrozil; Heterozygote; Humans; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Triglycerides

1989
Comparison of low-dose simvastatin and gemfibrozil in the treatment of elevated plasma cholesterol. A multicenter study. The Simvastatin Study Group.
    The American journal of medicine, 1989, Oct-16, Volume: 87, Issue:4A

    Topics: Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Double-Blind Method; Female; Gemfibrozil; Humans; Lovastatin; Male; Middle Aged; Multicenter Studies as Topic; Random Allocation; Simvastatin

1989
Comparison of lovastatin and gemfibrozil in normolipidemic patients with hypoalphalipoproteinemia.
    JAMA, 1989, Dec-08, Volume: 262, Issue:22

    Topics: Adult; Aged; Analysis of Variance; Apolipoproteins; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Gemfibrozil; Humans; Hypolipoproteinemias; Lipids; Lipoproteins, HDL; Lovastatin; Male; Middle Aged; Random Allocation; Triglycerides

1989
Gemfibrozil alone and in combination with lovastatin for treatment of hypertriglyceridemia in NIDDM.
    Diabetes, 1989, Volume: 38, Issue:3

    Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Gemfibrozil; Humans; Hypertriglyceridemia; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged

1989
Comparison between lovastatin and gemfibrozil in the treatment of primary hypercholesterolemia: the Finnish Multicenter Study.
    The American journal of cardiology, 1988, Nov-11, Volume: 62, Issue:15

    Topics: Adult; Double-Blind Method; Female; Finland; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lovastatin; Male; Multicenter Studies as Topic; Random Allocation

1988
Combination drug therapy for familial combined hyperlipidemia.
    Annals of internal medicine, 1988, Jul-01, Volume: 109, Issue:1

    Topics: Adult; Cholelithiasis; Colestipol; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pentanoic Acids; Polyamines; Random Allocation; Ultrasonography; Valerates

1988
A randomized trial to assess effectiveness and cost in clinical practice: rationale and design of the Cholesterol Reduction Intervention Study (CRIS).
    Controlled clinical trials, 1995, Volume: 16, Issue:1

    Topics: Adult; Aged; Cholesterol, LDL; Coronary Disease; Cost-Benefit Analysis; Costs and Cost Analysis; Follow-Up Studies; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Middle Aged; Niacin; Patient Selection; Prospective Studies; Risk Factors; Treatment Outcome

1995
Changes in plasma lipid and apolipoprotein levels between heparin-induced extracorporeal low-density lipoprotein precipitation (HELP) treatments.
    The American journal of cardiology, 1995, Jun-01, Volume: 75, Issue:16

    Topics: Adult; Apolipoproteins; Apolipoproteins A; Apolipoproteins B; Blood Component Removal; Chemical Precipitation; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Combined Modality Therapy; Extracorporeal Circulation; Female; Gemfibrozil; Heparin; Humans; Hypercholesterolemia; Hyperlipidemias; Lipids; Lipoproteins, LDL; Lovastatin; Male

1995
Effect of gemfibrozil versus lovastatin on increased serum lipoprotein(a) levels of patients with hypercholesterolemia.
    International journal of cardiology, 1995, Volume: 48, Issue:2

    Topics: Adult; Aged; Cholesterol; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lipoprotein(a); Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Lovastatin; Male; Middle Aged; Treatment Outcome; Triglycerides

1995
Comparison of gemfibrozil versus simvastatin in familial combined hyperlipidemia and effects on apolipoprotein-B-containing lipoproteins, low-density lipoprotein subfraction profile, and low-density lipoprotein oxidizability.
    The American journal of cardiology, 1995, Feb-15, Volume: 75, Issue:5

    Topics: Adult; Apolipoproteins B; Double-Blind Method; Female; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lipids; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Oxidation-Reduction; Simvastatin; Triglycerides

1995
A comparison between the effects of gemfibrozil and simvastatin on insulin sensitivity in patients with non-insulin-dependent diabetes mellitus and hyperlipoproteinemia.
    Metabolism: clinical and experimental, 1995, Volume: 44, Issue:2

    Topics: Aged; Body Weight; Diabetes Complications; Diabetes Mellitus; Double-Blind Method; Female; Gemfibrozil; Glucose Tolerance Test; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Insulin; Lipoprotein Lipase; Lipoprotein(a); Lipoproteins, LDL; Lipoproteins, VLDL; Lovastatin; Male; Middle Aged; Simvastatin

1995
[Clinical evaluation of simvastatin in the treatment of hyperlipidemia].
    Zhonghua xin xue guan bing za zhi, 1993, Volume: 21, Issue:4

    Topics: Adult; Aged; Anticholesteremic Agents; Apolipoprotein A-I; Apolipoproteins B; Cholesterol; Cholesterol, HDL; Female; Gemfibrozil; Humans; Hyperlipidemias; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1993
Effect of gemfibrozil and lovastatin on postprandial lipoprotein clearance in the hypoalphalipoproteinemia and hypertriglyceridemia syndrome.
    Atherosclerosis, 1993, Volume: 100, Issue:1

    Topics: Adult; Dietary Fats; Double-Blind Method; Eating; Fasting; Gemfibrozil; Humans; Hypertriglyceridemia; Hypolipoproteinemias; Lipids; Lipoprotein Lipase; Lipoproteins; Lipoproteins, HDL; Lovastatin; Male; Middle Aged; Syndrome; Triglycerides

1993
[Comparison of the efficacy between simvastatin and gemfibrozil in primary hypercholesterolemia].
    La Revue de medecine interne, 1993, Volume: 14, Issue:4

    Topics: Adult; Aged; Double-Blind Method; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Simvastatin

1993
The impact of a short course of three lipid lowering drugs on fat oxidation during exercise in healthy volunteers.
    Postgraduate medical journal, 1993, Volume: 69, Issue:809

    Topics: Adult; Anticholesteremic Agents; Blood Pressure; Energy Metabolism; Exercise; Exercise Test; Exercise Tolerance; Fatty Acids, Nonesterified; Gemfibrozil; Heart Rate; Humans; Hydroxymethylglutaryl CoA Reductases; Hypolipidemic Agents; Lovastatin; Male; Oxidation-Reduction; Oxygen Consumption; Pyrazines; Random Allocation; Simvastatin; Single-Blind Method

1993
Comparison of the efficacy of simvastatin and standard fibrate therapy in the treatment of primary hypercholesterolemia and combined hyperlipidemia.
    Clinical cardiology, 1995, Volume: 18, Issue:11

    Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol, LDL; Clofibric Acid; Fatty Acids, Volatile; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1995
[Multicenter comparative study on safety, tolerance, and effectiveness of lovastatin combined or not with cholestyramine, and gemfibrozil combined or not with cholestyramine in the treatment of primary hypercholesterolemia].
    Medicina clinica, 1996, May-25, Volume: 106, Issue:20

    Topics: Adolescent; Adult; Aged; Anticholesteremic Agents; Cholesterol; Cholestyramine Resin; Double-Blind Method; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Triglycerides

1996
Effects of gemfibrozil or simvastatin on apolipoprotein-B-containing lipoproteins, apolipoprotein-CIII and lipoprotein(a) in familial combined hyperlipidaemia.
    The Netherlands journal of medicine, 1996, Volume: 49, Issue:2

    Topics: Adult; Apolipoprotein C-III; Apolipoproteins B; Apolipoproteins C; Cholesterol; Double-Blind Method; Enzyme Inhibitors; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lipoprotein(a); Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1996
Lipid-lowering effects of simvastatin and gemfibrozil in CAPD patients: a prospective cross-over study.
    Advances in peritoneal dialysis. Conference on Peritoneal Dialysis, 1996, Volume: 12

    Topics: Adult; Aged; Cholesterol; Combined Modality Therapy; Cross-Over Studies; Diet, Fat-Restricted; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Kidney Failure, Chronic; Lovastatin; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Prospective Studies; Simvastatin; Triglycerides

1996
Four years' treatment efficacy of patients with severe hyperlipidemia. Lipid lowering drugs versus LDL-apheresis.
    The International journal of artificial organs, 1995, Volume: 18, Issue:12

    Topics: Adolescent; Adult; Anticholesteremic Agents; Blood Component Removal; Cholesterol, HDL; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Colestipol; Coronary Disease; Enzyme-Linked Immunosorbent Assay; Female; Fenofibrate; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Longitudinal Studies; Lovastatin; Male; Middle Aged; Niacin; Pravastatin; Quality of Life

1995
A comparative study of the efficacy of simvastatin and gemfibrozil in combined hyperlipoproteinemia: prediction of response by baseline lipids, apo E genotype, lipoprotein(a) and insulin.
    Atherosclerosis, 1997, Mar-21, Volume: 129, Issue:2

    Topics: Anticholesteremic Agents; Apolipoproteins E; Cholesterol; Cross-Over Studies; Dietary Fats; Gemfibrozil; Genotype; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemias; Hypolipidemic Agents; Insulin; Lipids; Lipoprotein(a); Lipoproteins; Lovastatin; Predictive Value of Tests; Simvastatin; Triglycerides

1997
Safety and efficacy of long-term statin-fibrate combinations in patients with refractory familial combined hyperlipidemia.
    The American journal of cardiology, 1997, Sep-01, Volume: 80, Issue:5

    Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins; Cholesterol, LDL; Clofibric Acid; Drug Therapy, Combination; Female; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin; Treatment Outcome

1997
[Gemfibrozil reduces elevated lipoprotein (a) levels in hypercholesterolemic patients].
    Arquivos brasileiros de cardiologia, 1997, Volume: 68, Issue:4

    Topics: Analysis of Variance; Anticholesteremic Agents; Chi-Square Distribution; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipoprotein(a); Lovastatin; Male; Middle Aged

1997
Lipoprotein composition and oxidative modification during therapy with gemfibrozil and lovastatin in patients with combined hyperlipidaemia.
    British journal of clinical pharmacology, 1998, Volume: 45, Issue:3

    Topics: Double-Blind Method; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lipoproteins, LDL; Lipoproteins, VLDL; Lovastatin; Oxidation-Reduction; Placebos

1998
Randomized crossover study of gemfibrozil versus lovastatin in familial combined hyperlipidemia: additive effects of combination treatment on lipid regulation.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:1

    Topics: Adult; Aged; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hypolipidemic Agents; Lipid Metabolism; Lovastatin; Male; Middle Aged

1999
Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate.
    Clinical pharmacology and therapeutics, 2001, Volume: 69, Issue:5

    Topics: Adult; Area Under Curve; Bezafibrate; Cross-Over Studies; Drug Interactions; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Male

2001
Effects of hypolipidemic treatment on serum markers of vascular inflammation in dyslipidemic men.
    Medical science monitor : international medical journal of experimental and clinical research, 2003, Volume: 9, Issue:3

    Topics: Adult; Bezafibrate; Biomarkers; Chemokine CCL2; E-Selectin; Gemfibrozil; Humans; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Inflammation Mediators; Lovastatin; Male; Middle Aged; Simvastatin; Vascular Cell Adhesion Molecule-1

2003

Other Studies

65 other study(ies) available for gemfibrozil and lovastatin

ArticleYear
Discovery of 1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-(4 -hydroxyphenyl)-2-azetidinone (SCH 58235): a designed, potent, orally active inhibitor of cholesterol absorption.
    Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6

    Topics: Animals; Anticholesteremic Agents; Azetidines; Cholesterol; Cricetinae; Drug Design; Ezetimibe; Liver; Structure-Activity Relationship

1998
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Identifying off-target effects and hidden phenotypes of drugs in human cells.
    Nature chemical biology, 2006, Volume: 2, Issue:6

    Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship

2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
A retrospective review of the use of lipid-lowering agents in combination, specifically, gemfibrozil and lovastatin.
    Pharmacotherapy, 1992, Volume: 12, Issue:6

    Topics: Aged; Alanine Transaminase; Cholestyramine Resin; Colestipol; Creatine Kinase; Drug Interactions; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Lipids; Lovastatin; Male; Middle Aged; Niacin; Retrospective Studies

1992
Lovastatin/gemfibrozil myopathy: a clinical, histochemical, and ultrastructural study.
    European neurology, 1992, Volume: 32, Issue:5

    Topics: Drug Therapy, Combination; Female; Gemfibrozil; Humans; Lovastatin; Microscopy, Electron; Middle Aged; Muscles; Muscular Diseases

1992
Efficacy and cost-effectiveness of simvastatin and gemfibrozil in the treatment of hyperlipidaemia.
    Annals of the Academy of Medicine, Singapore, 1992, Volume: 21, Issue:1

    Topics: Cost-Benefit Analysis; Drug Evaluation; Female; Follow-Up Studies; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids; Lovastatin; Male; Middle Aged; Simvastatin

1992
Effects of lovastatin and gemfibrozil on high-density lipoprotein subfraction density and composition in patients with familial hypercholesterolemia.
    The Journal of laboratory and clinical medicine, 1992, Volume: 120, Issue:1

    Topics: Adult; Apolipoprotein A-I; Apolipoprotein A-II; Centrifugation, Density Gradient; Chemical Fractionation; Cholesterol Esters; Cholesterol, HDL; Female; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Lipoproteins, HDL; Lovastatin; Male; Middle Aged; Triglycerides

1992
Gemfibrozil-lovastatin therapy for primary hyperlipoproteinemias.
    The American journal of cardiology, 1992, Jul-01, Volume: 70, Issue:1

    Topics: Adult; Aged; Analysis of Variance; Cholesterol; Combined Modality Therapy; Creatine Kinase; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hyperlipoproteinemias; Liver Function Tests; Lovastatin; Male; Middle Aged; Myositis; Retrospective Studies; Triglycerides

1992
Choice of cholesterol-lowering drugs.
    The Medical letter on drugs and therapeutics, 1991, Jan-11, Volume: 33, Issue:835

    Topics: Anticholesteremic Agents; Cholestyramine Resin; Clofibrate; Colestipol; Fish Oils; Gemfibrozil; Humans; Lovastatin; Neomycin; Niacin; Probucol

1991
[Myopathy during treatment with fibrates and lovastatin].
    Ugeskrift for laeger, 1991, Mar-18, Volume: 153, Issue:12

    Topics: Aged; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Lovastatin; Male; Middle Aged; Myositis

1991
Low density lipoprotein density and composition in hypercholesterolaemic men treated with HMG CoA reductase inhibitors and gemfibrozil.
    Journal of internal medicine, 1991, Volume: 229, Issue:5

    Topics: Adult; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Simvastatin

1991
Lovastatin and gemfibrozil in the treatment of type 2a and type 2b hyperlipoproteinemia.
    European journal of clinical pharmacology, 1991, Volume: 40 Suppl 1

    Topics: Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Lovastatin

1991
Cholesterol-lowering agent myopathy (CLAM).
    Neurology, 1991, Volume: 41, Issue:7

    Topics: Aged; Anticholesteremic Agents; Female; Gemfibrozil; Humans; Lovastatin; Muscular Diseases

1991
Treatment choices for hypertriglyceridemia.
    JAMA, 1990, Dec-05, Volume: 264, Issue:21

    Topics: Gemfibrozil; Humans; Hypertriglyceridemia; Lovastatin

1990
Myopathy and rhabdomyolysis with lovastatin taken with gemfibrozil.
    JAMA, 1990, Dec-19, Volume: 264, Issue:23

    Topics: Adolescent; Creatine Kinase; Drug Synergism; Drug Therapy, Combination; Gemfibrozil; Humans; Isoenzymes; Lovastatin; Male; Middle Aged; Muscular Diseases; Rhabdomyolysis

1990
Rhabdomyolysis and acute renal failure induced by combination lovastatin and gemfibrozil therapy.
    Annals of internal medicine, 1990, Feb-01, Volume: 112, Issue:3

    Topics: Acute Kidney Injury; Biological Assay; Drug Interactions; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Lovastatin; Male; Middle Aged; Rhabdomyolysis

1990
[A case of familial hypercholesterolemia with therapeutic difficulties].
    Lakartidningen, 1990, Mar-07, Volume: 87, Issue:10

    Topics: Adult; Bezafibrate; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Lovastatin; Male; Nicotinic Acids; Simvastatin

1990
Safety and efficacy of combined gemfibrozil-lovastatin therapy for primary dyslipoproteinemias.
    The Journal of laboratory and clinical medicine, 1990, Volume: 115, Issue:5

    Topics: Adult; Aged; Arteriosclerosis; Cholesterol; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Lipid Metabolism, Inborn Errors; Lipids; Lipoproteins; Lovastatin; Male; Middle Aged

1990
Myopathy and rhabdomyolysis associated with lovastatin-gemfibrozil combination therapy.
    JAMA, 1990, Jul-04, Volume: 264, Issue:1

    Topics: Acute Kidney Injury; Adult; Aged; Creatine Kinase; Drug Interactions; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Middle Aged; Muscular Diseases; Rhabdomyolysis

1990
Lovastatin-induced acute rhabdomyolysis.
    Postgraduate medical journal, 1990, Volume: 66, Issue:774

    Topics: Acute Disease; Age Factors; Aged; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Kidney Failure, Chronic; Lovastatin; Muscles; Rhabdomyolysis

1990
The role of cholesterol-lowering agents in drug-induced rhabdomyolysis and polymyositis.
    Arthritis and rheumatism, 1989, Volume: 32, Issue:3

    Topics: Aged; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Lovastatin; Myositis; Rhabdomyolysis

1989
Lovastatin therapy in familial dysbetalipoproteinemia: effects on kinetics of apolipoprotein B.
    Atherosclerosis, 1988, Volume: 70, Issue:1-2

    Topics: Adult; Apolipoproteins B; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Female; Gemfibrozil; Humans; Hyperlipoproteinemia Type III; Kinetics; Lipoproteins, VLDL; Lovastatin; Male; Middle Aged; Pentanoic Acids; Triglycerides

1988
[Therapeutic possibilities of a newly registered lipid suppressor].
    Lakartidningen, 1988, Oct-05, Volume: 85, Issue:40

    Topics: Anticholesteremic Agents; Colestipol; Gemfibrozil; Humans; Lovastatin; Simvastatin

1988
Current and new therapy for hypercholesterolemia.
    The Journal of the American Osteopathic Association, 1988, Volume: 88, Issue:7

    Topics: Anticholesteremic Agents; Colestipol; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Niacin; Probucol

1988
Current pharmacologic treatment of elevated serum cholesterol.
    Circulation, 1987, Volume: 76, Issue:3

    Topics: Adult; Anticholesteremic Agents; Cholesterol; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Colestipol; Drug Tolerance; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemia Type II; Lovastatin; Male; Middle Aged; Naphthalenes; Neomycin; Niacin; Pentanoic Acids; Probucol; Simvastatin; Triglycerides

1987
Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats.
    Atherosclerosis, 1983, Volume: 48, Issue:3

    Topics: Animals; Anticholesteremic Agents; Bezafibrate; Caprylates; Carbon Radioisotopes; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Clofibrate; Gemfibrozil; Hypolipidemic Agents; Liver; Lovastatin; Male; Mevalonic Acid; Naphthalenes; Pentanoic Acids; Rats; Rats, Inbred F344; Sterols; Valerates

1983
HMG-CoA reductase inhibitors, gemfibrozil, and myopathy.
    The American journal of cardiology, 1995, Apr-15, Volume: 75, Issue:12

    Topics: Drug Combinations; Drug Interactions; Follow-Up Studies; Gemfibrozil; Humans; Lovastatin; Muscular Diseases; Pravastatin

1995
Warfarin therapy.
    Mayo Clinic proceedings, 1995, Volume: 70, Issue:5

    Topics: Drug Synergism; Gemfibrozil; Humans; Lovastatin; Warfarin

1995
Postprandial apolipoprotein B100 and B48 metabolism in familial combined hyperlipidaemia before and after reduction of fasting plasma triglycerides.
    European journal of clinical investigation, 1994, Volume: 24, Issue:10

    Topics: Adult; Aged; Apolipoprotein B-100; Apolipoprotein B-48; Apolipoproteins B; Child; Cholesterol; Drug Therapy, Combination; Fasting; Female; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides

1994
Fish oil (omega-3 fatty acids) in treatment of hypertriglyceridemia. A practical approach for the primary care physician.
    The Journal of the Kentucky Medical Association, 1994, Volume: 92, Issue:3

    Topics: Aged; Clofibrate; Drug Therapy, Combination; Fatty Acids, Omega-3; Female; Gemfibrozil; Humans; Hypertriglyceridemia; Lipids; Lovastatin; Niacin; Primary Health Care

1994
Rhabdomyolysis and acute renal failure in a heart transplant recipient treated with hypolipemiants.
    Nephron, 1994, Volume: 66, Issue:2

    Topics: Acute Kidney Injury; Gemfibrozil; Heart Transplantation; Humans; Hyperlipidemias; Leprostatic Agents; Lovastatin; Male; Middle Aged; Rhabdomyolysis

1994
Lovastatin and myopathy.
    The American journal of medicine, 1994, Volume: 96, Issue:3

    Topics: Drug Synergism; Gemfibrozil; Humans; Lovastatin; Muscular Diseases; Pravastatin

1994
Effect of three fibrate derivatives and of two HMG-CoA reductase inhibitors on plasma fibrinogen level in patients with primary hypercholesterolemia.
    Thrombosis and haemostasis, 1993, Aug-02, Volume: 70, Issue:2

    Topics: Adult; Aged; Bezafibrate; Cholesterol, Dietary; Combined Modality Therapy; Female; Fenofibrate; Fibrinogen; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin

1993
Rhabdomyolysis and renal failure secondary to combination therapy of hyperlipidemia with lovastatin and gemfibozil.
    Connecticut medicine, 1993, Volume: 57, Issue:9

    Topics: Acute Kidney Injury; Drug Therapy, Combination; Gemfibrozil; Humans; Hyperlipidemias; Lovastatin; Male; Middle Aged; Rhabdomyolysis

1993
Lipoprotein responses to treatment with lovastatin, gemfibrozil, and nicotinic acid in normolipidemic patients with hypoalphalipoproteinemia.
    Archives of internal medicine, 1994, Jan-10, Volume: 154, Issue:1

    Topics: Gemfibrozil; Humans; Hypolipoproteinemias; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Male; Middle Aged; Niacin

1994
Gemfibrozil-lovastatin-associated myalgia.
    The American journal of cardiology, 1993, Feb-15, Volume: 71, Issue:5

    Topics: Drug Therapy, Combination; Gemfibrozil; Humans; Lovastatin; Muscular Diseases

1993
Treatment of hyperlipidemia in heart transplant recipients with gemfibrozil +/- lovastatin.
    The American journal of cardiology, 1993, Jun-15, Volume: 71, Issue:16

    Topics: Female; Gemfibrozil; Heart Transplantation; Humans; Hyperlipidemias; Lovastatin; Male; Middle Aged; Retrospective Studies; Treatment Outcome

1993
Pancreatitis and rhabdomyolysis associated with lovastatin-gemfibrozil therapy.
    Journal of clinical gastroenterology, 1995, Volume: 21, Issue:4

    Topics: Acute Disease; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Middle Aged; Pancreatic Pseudocyst; Pancreatitis; Rhabdomyolysis

1995
Carcinogenicity of lipid-lowering drugs.
    JAMA, 1996, May-15, Volume: 275, Issue:19

    Topics: Acyl Coenzyme A; Gemfibrozil; Humans; Hypolipidemic Agents; Liver; Liver Neoplasms; Lovastatin

1996
Fenofibrate, probucol, and other lipid-lowering treatments in heart transplant recipients.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1996, Volume: 15, Issue:5

    Topics: Anticholesteremic Agents; Cholestyramine Resin; Cyclosporine; Drug Interactions; Fenofibrate; Gemfibrozil; Heart Transplantation; Humans; Hypolipidemic Agents; Immunosuppressive Agents; Lovastatin; Probucol; Simvastatin

1996
Reasons for stopping drugs are monitored in New Zealand.
    BMJ (Clinical research ed.), 1996, Sep-21, Volume: 313, Issue:7059

    Topics: Adverse Drug Reaction Reporting Systems; Bezafibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Lovastatin; New Zealand; Product Surveillance, Postmarketing; Simvastatin

1996
Inhibition of acyl-CoA: cholesterol acyltransferase decreases apolipoprotein B-100-containing lipoprotein secretion from HepG2 cells.
    Journal of lipid research, 1996, Volume: 37, Issue:1

    Topics: Albumins; Aniline Compounds; Apolipoprotein B-100; Apolipoproteins B; Enzyme Inhibitors; Gemfibrozil; Humans; Hydroxycholesterols; Hypolipidemic Agents; Lipids; Liver; Lovastatin; Phenylurea Compounds; Sterol O-Acyltransferase; Tumor Cells, Cultured

1996
Myopathy associated with lipid lowering therapy in patients with previously undiagnosed or undertreated hypothyroidism.
    Clinica chimica acta; international journal of clinical chemistry, 1996, Oct-15, Volume: 254, Issue:1

    Topics: Aged; Anticholesteremic Agents; Fatty Acids, Monounsaturated; Female; Fluvastatin; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Hypothyroidism; Indoles; Lovastatin; Male; Middle Aged; Neuromuscular Diseases; Simvastatin; Thyroxine

1996
Possible increased risk of rhabdomyolysis during concomitant use of simvastatin and gemfibrozil.
    Journal of internal medicine, 1996, Volume: 240, Issue:6

    Topics: Drug Synergism; Gemfibrozil; Humans; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Rhabdomyolysis; Risk; Simvastatin

1996
Effects of initial BMI and on-treatment weight change on the lipid-lowering efficacy of fibrates.
    International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity, 1997, Volume: 21, Issue:2

    Topics: Body Mass Index; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipids; Lovastatin; Male; Middle Aged; Prospective Studies; Sex Factors; Simvastatin; Weight Loss

1997
The Scandinavian Simvastatin Survival Study (4S) subgroup analysis of diabetic subjects: implications for the prevention of coronary heart disease.
    Diabetes care, 1997, Volume: 20, Issue:4

    Topics: Anticholesteremic Agents; Cholesterol, HDL; Coronary Disease; Diabetic Angiopathies; Gemfibrozil; Humans; Hypolipidemic Agents; Lovastatin; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Risk Factors; Scandinavian and Nordic Countries; Simvastatin; Survival Rate; Triglycerides

1997
Rhabdomyolysis associated with simvastatin-gemfibrozil therapy.
    Southern medical journal, 1997, Volume: 90, Issue:5

    Topics: Anticholesteremic Agents; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Middle Aged; Muscular Diseases; Rhabdomyolysis; Simvastatin

1997
Lack of left ventricular dysfunction associated with sustained exposure to hyperlipidemia following lung transplantation.
    Chest, 1997, Volume: 112, Issue:4

    Topics: Anticholesteremic Agents; Arteriosclerosis; Cholesterol; Cholestyramine Resin; Echocardiography; Female; Follow-Up Studies; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hyperlipoproteinemias; Hypertriglyceridemia; Hypolipidemic Agents; Immunosuppressive Agents; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Lovastatin; Lung Transplantation; Male; Middle Aged; Myocardial Ischemia; Probucol; Radionuclide Angiography; Retrospective Studies; Triglycerides; Ventricular Dysfunction, Left; Ventricular Function, Left

1997
Lack of interaction of apolipoprotein E phenotype with the lipoprotein response to lovastatin or gemfibrozil in patients with primary hypercholesterolemia.
    Metabolism: clinical and experimental, 1998, Volume: 47, Issue:5

    Topics: Adult; Aged; Anticholesteremic Agents; Apolipoproteins E; Data Interpretation, Statistical; Drug Interactions; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Phenotype; Polymorphism, Genetic

1998
Apolipoprotein E*3-Leiden transgenic mice as a test model for hypolipidaemic drugs.
    Arzneimittel-Forschung, 1998, Volume: 48, Issue:4

    Topics: Animals; Anticoagulants; Apolipoprotein E3; Apolipoproteins E; Cholesterol; Drug Evaluation, Preclinical; Gemfibrozil; Heparin; Hypolipidemic Agents; Lactones; Lipids; Lipoprotein Lipase; Liver; Lovastatin; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; RNA, Messenger; Triglycerides

1998
Effects of lovastatin and gemfibrozil in subjects with high ratios of total cholesterol to high-density lipoprotein cholesterol.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 1999, Volume: 98, Issue:2

    Topics: Adult; Aged; Anticholesteremic Agents; Blood Glucose; Cholesterol; Cholesterol, HDL; Female; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Insulin; Leptin; Lovastatin; Male; Middle Aged; Obesity; Proteins

1999
Long-term safety and efficacy of combination gemfibrozil and HMG-CoA reductase inhibitors for the treatment of mixed lipid disorders.
    American heart journal, 1999, Volume: 138, Issue:1 Pt 1

    Topics: Aged; Anticholesteremic Agents; Atorvastatin; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Indoles; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Prospective Studies; Pyrroles; Simvastatin; Time Factors; Treatment Outcome

1999
Rhabdomyolysis associated with the combined use of hydroxymethylglutaryl-coenzyme A reductase inhibitors with gemfibrozil and macrolide antibiotics.
    Connecticut medicine, 1999, Volume: 63, Issue:8

    Topics: Adult; Aged; Anti-Bacterial Agents; Anticholesteremic Agents; Clarithromycin; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Rhabdomyolysis

1999
Effect of dietary lipid-lowering drugs upon plasma lipids and egg yolk cholesterol levels of laying hens.
    Journal of agricultural and food chemistry, 1999, Volume: 47, Issue:11

    Topics: Animals; Anticholesteremic Agents; Chickens; Cholesterol; Dietary Supplements; Egg Yolk; Female; Gemfibrozil; Lipids; Lovastatin; Probucol; Triglycerides

1999
Cholesterol-lowering drugs. Some drugs with demonstrated efficacy but different benefits in primary and secondary prevention.
    Prescrire international, 1999, Volume: 8, Issue:42

    Topics: Anticholesteremic Agents; Bezafibrate; Cholestyramine Resin; Clinical Trials as Topic; Clofibrate; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Myocardial Infarction; Pravastatin; Treatment Outcome

1999
Therapy and clinical trials.
    Current opinion in lipidology, 2002, Volume: 13, Issue:1

    Topics: Cholesterol, HDL; Clinical Trials as Topic; Coronary Disease; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Neoplasms; Risk Assessment; Simvastatin; Venous Thrombosis

2002
Efficacy of lipid-lowering medications in patients treated with clozapine: a naturalistic study.
    Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:3

    Topics: Adult; Antipsychotic Agents; Atorvastatin; Cholesterol; Clozapine; Female; Fenofibrate; Gemfibrozil; Heptanoic Acids; Humans; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Male; Middle Aged; Pravastatin; Psychotic Disorders; Pyrroles; Retrospective Studies; Schizophrenia; Treatment Outcome; Triglycerides

2008
Establishment and characterization of a mouse model of rhabdomyolysis by coadministration of statin and fibrate.
    Toxicology letters, 2019, Jun-01, Volume: 307

    Topics: Animals; Caspase 3; Caspase 7; Disease Models, Animal; Drug Interactions; Female; Fibric Acids; Gemfibrozil; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lovastatin; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Real-Time Polymerase Chain Reaction; Rhabdomyolysis

2019