gemfibrozil and ketoprofen

gemfibrozil has been researched along with ketoprofen in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (42.86)29.6817
2010's12 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T1
Deguchi, T; Furuta, Y; Fusegawa, K; Hirouchi, M; Igeta, K; Ikenaga, H; Iwasaki, M; Izumi, T; Kurihara, A; Murata, S; Okazaki, O; Suzuki, N; Watanabe, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Burchell, B; Coffey, MJ; Findlay, KA; Riley, RJ; Soars, MG1
Kristl, A; Legen, I; Zakelj, S1
Lin, AY; Reinhard, M1
Balchen, M; Gjelstad, A; Pedersen-Bjergaard, S; Rasmussen, KE1
Kołodziejczyk, MK; Lukosek, M; Nachajski, MJ; Woskowicz, MH; Zgoda, MM1
Asami, M; Fujiwara, J; Kunikane, S; Manabe, S; Matsuda, M; Simazaki, D1
Gunsch, CK; Wang, S1
Dickenson, ER; Drewes, JE; Hoppe-Jones, C1
Ademollo, N; Capri, S; Patrolecco, L1
Alidina, M; Drewes, JE; Shewchuk, J1
Gjelstad, A; Pedersen-Bjergaard, S; Roldán-Pijuán, M1

Reviews

1 review(s) available for gemfibrozil and ketoprofen

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

20 other study(ies) available for gemfibrozil and ketoprofen

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney

2011
Human pharmacokinetic prediction of UDP-glucuronosyltransferase substrates with an animal scale-up approach.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5

    Topics: Administration, Oral; Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Area Under Curve; Cytochrome P-450 Enzyme System; Dogs; Drug Evaluation, Preclinical; Glucuronides; Glucuronosyltransferase; Half-Life; Humans; Macaca fascicularis; Male; Mice; Pharmaceutical Preparations; Predictive Value of Tests; Rats; Rats, Sprague-Dawley; Species Specificity

2011
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Evidence for significant differences in microsomal drug glucuronidation by canine and human liver and kidney.
    Drug metabolism and disposition: the biological fate of chemicals, 2001, Volume: 29, Issue:2

    Topics: Adult; Androstane-3,17-diol; Animals; Dogs; Female; Furosemide; Gemfibrozil; Glucuronidase; Glucuronides; Humans; Ketoprofen; Kidney; Kinetics; Male; Microsomes; Microsomes, Liver; Middle Aged; Models, Animal; Propofol; Species Specificity

2001
Polarised transport of monocarboxylic acid type drugs across rat jejunum in vitro: the effect of mucolysis and ATP-depletion.
    International journal of pharmaceutics, 2003, Apr-30, Volume: 256, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Carboxylic Acids; Cell Membrane Permeability; Cysteine; Gemfibrozil; Hydrogen-Ion Concentration; Ibuprofen; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Ketoprofen; Male; Membranes, Artificial; Rats; Rats, Wistar; Sodium Azide

2003
Photodegradation of common environmental pharmaceuticals and estrogens in river water.
    Environmental toxicology and chemistry, 2005, Volume: 24, Issue:6

    Topics: Chromatography, High Pressure Liquid; Environmental Monitoring; Estrogens; Gemfibrozil; Half-Life; Ibuprofen; Ketoprofen; Naproxen; Oxygen; Pharmaceutical Preparations; Photolysis; Propranolol; Rivers; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical

2005
Electrokinetic migration of acidic drugs across a supported liquid membrane.
    Journal of chromatography. A, 2007, Jun-08, Volume: 1152, Issue:1-2

    Topics: Acids; Chromatography, Micellar Electrokinetic Capillary; Electrophoresis, Capillary; Flurbiprofen; Gemfibrozil; Heptanol; Hydrogen-Ion Concentration; Ketoprofen; Membranes, Artificial; Naproxen; Pharmaceutical Preparations; Probenecid; Reproducibility of Results; Warfarin

2007
Solubilizing properties of new surface-active agents, products of selective oxyethylation of cholic acid. Part I.
    Polimery w medycynie, 2007, Volume: 37, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Chlorates; Diclofenac; Fenofibrate; Gemfibrozil; Hypolipidemic Agents; Ketoprofen; Micelles; Models, Theoretical; Nifedipine; Solubility; Solutions; Surface-Active Agents; Vasodilator Agents; Viscosity

2007
Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2008, Volume: 58, Issue:5

    Topics: Antipyrine; Charcoal; Clofibric Acid; Diclofenac; Fenoprofen; Gemfibrozil; Halogenation; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Water Pollutants, Chemical; Water Purification; Water Supply

2008
Effects of selected pharmaceutically active compounds on treatment performance in sequencing batch reactors mimicking wastewater treatment plants operations.
    Water research, 2011, Volume: 45, Issue:11

    Topics: Bacteria; Biodiversity; Bioreactors; Carbamazepine; Drug-Related Side Effects and Adverse Reactions; Gemfibrozil; Ketoprofen; Microbial Consortia; Naproxen; Pharmaceutical Preparations; Waste Disposal, Fluid; Water Microbiology; Water Pollutants, Chemical

2011
The role of microbial adaptation and biodegradable dissolved organic carbon on the attenuation of trace organic chemicals during groundwater recharge.
    The Science of the total environment, 2012, Oct-15, Volume: 437

    Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Adaptation, Physiological; Biodegradation, Environmental; Carbon; Clofibric Acid; Gemfibrozil; Groundwater; Ibuprofen; Ketoprofen; Naproxen; Organic Chemicals; Soil Microbiology; Water Microbiology; Water Pollutants, Chemical; Water Purification

2012
Occurrence of selected pharmaceuticals in the principal sewage treatment plants in Rome (Italy) and in the receiving surface waters.
    Environmental science and pollution research international, 2015, Volume: 22, Issue:8

    Topics: Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Estrone; Gemfibrozil; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Rome; Seasons; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical

2015
Effect of temperature on removal of trace organic chemicals in managed aquifer recharge systems.
    Chemosphere, 2015, Volume: 122

    Topics: Benzophenones; Diclofenac; Gemfibrozil; Groundwater; Ketoprofen; Naproxen; Soil Microbiology; Temperature; Trimethoprim; Water Pollutants, Chemical

2015
Parallel artificial liquid membrane extraction of acidic drugs from human plasma.
    Analytical and bioanalytical chemistry, 2015, Volume: 407, Issue:10

    Topics: Calibration; Chromatography, High Pressure Liquid; Diclofenac; Equipment Design; Flurbiprofen; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Liquid-Liquid Extraction; Membranes, Artificial; Pharmaceutical Preparations; Polypropylenes; Polyvinyls

2015