gemfibrozil has been researched along with ibuprofen in 36 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.78) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 12 (33.33) | 29.6817 |
| 2010's | 21 (58.33) | 24.3611 |
| 2020's | 2 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Dalvie, D; Fu, Y; Khojasteh, SC; Ma, Y; Zhang, D | 1 |
| Hengy, H; Kölle, EU | 1 |
| Arnold, HG; Baginski, RM; Jux, U; Krönke, M; Seng, PN | 1 |
| Khan, AI; Lei, L; Norquist, AJ; O'Hare, D | 1 |
| Kristl, A; Legen, I; Zakelj, S | 1 |
| Lin, AY; Reinhard, M | 1 |
| Backman, JT; Neuvonen, PJ; Niemi, M; Tornio, A | 1 |
| Nogueira, JM; Portugal, FC; Silva, AR | 1 |
| Asami, M; Fujiwara, J; Kunikane, S; Manabe, S; Matsuda, M; Simazaki, D | 1 |
| Alonso, E; Aparicio, I; Camacho-Muñoz, D; Martín, J; Santos, JL | 1 |
| Jójártné, LO; Mártha, C; Szabóné, RP | 1 |
| Fernandes, D; Porte, C; Schnell, S | 1 |
| Bragg, LM; Dixon, G; Oakes, KD; Pawliszyn, J; Servos, MR; Wang, S | 1 |
| Dickenson, ER; Drewes, JE; Hoppe-Jones, C | 1 |
| Bayen, S; Desai, MM; Kelly, BC; Ooi, SK; Zhang, H | 1 |
| Zsila, F | 1 |
| Gagnon, GA; Krkošek, WH; Payne, SJ | 1 |
| Ademollo, N; Capri, S; Patrolecco, L | 1 |
| Gjelstad, A; Pedersen-Bjergaard, S; Roldán-Pijuán, M | 1 |
| Groza, LG; Hebig, KH; Ptacek, CJ; Sabourin, MJ; Scheytt, TJ | 1 |
| Bodnar, O; Falfushynska, H; Horyn, O; Kasianchuk, N; Poznanskyi, D | 1 |
| Bila, DM; da Fonseca, EM; da Silva de Freitas, A; de Oliveira Santos, AD; do Nascimento, MTL; Dos Santos, RF; Felix, LC; Hauser-Davis, RA; Neto, JAB; Sanson, AL | 1 |
2 review(s) available for gemfibrozil and ibuprofen
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Glucuronides as Potential Anionic Substrates of Human Cytochrome P450 2C8 (CYP2C8).
Topics: Anions; Binding Sites; Cytochrome P-450 CYP2C8; Drug Interactions; Glucuronides; Humans; Ligands | 2017 |
1 trial(s) available for gemfibrozil and ibuprofen
| Article | Year |
|---|---|
Stereoselective interaction between the CYP2C8 inhibitor gemfibrozil and racemic ibuprofen.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cross-Over Studies; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Drug Interactions; Enzyme Inhibitors; Female; Gemfibrozil; Genotype; Half-Life; Humans; Hypolipidemic Agents; Ibuprofen; Male; Stereoisomerism; Substrate Specificity | 2007 |
33 other study(ies) available for gemfibrozil and ibuprofen
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Determination of gemfibrozil in plasma by high performance liquid chromatography.
Topics: Chromatography, High Pressure Liquid; Gemfibrozil; Humans; Hypolipidemic Agents; Ibuprofen; Indicators and Reagents; Pentanoic Acids; Time Factors; Valerates | 1985 |
Detection of pharmaceutical contaminations of river, pond, and tap water from Cologne (Germany) and surroundings.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clofibric Acid; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Gemfibrozil; Germany; Humans; Ibuprofen; Pharmaceutical Preparations; Water Pollutants, Chemical; Water Supply | 2002 |
Intercalation and controlled release of pharmaceutically active compounds from a layered double hydroxide.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Diclofenac; Gemfibrozil; Hydrogen-Ion Concentration; Hydroxides; Ibuprofen; Naproxen; ortho-Aminobenzoates; Phenylacetates; Valproic Acid | 2001 |
Polarised transport of monocarboxylic acid type drugs across rat jejunum in vitro: the effect of mucolysis and ATP-depletion.
Topics: Adenosine Triphosphate; Animals; Biological Transport, Active; Carboxylic Acids; Cell Membrane Permeability; Cysteine; Gemfibrozil; Hydrogen-Ion Concentration; Ibuprofen; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Ketoprofen; Male; Membranes, Artificial; Rats; Rats, Wistar; Sodium Azide | 2003 |
Photodegradation of common environmental pharmaceuticals and estrogens in river water.
Topics: Chromatography, High Pressure Liquid; Environmental Monitoring; Estrogens; Gemfibrozil; Half-Life; Ibuprofen; Ketoprofen; Naproxen; Oxygen; Pharmaceutical Preparations; Photolysis; Propranolol; Rivers; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Water Pollutants, Chemical | 2005 |
Advances in stir bar sorptive extraction for the determination of acidic pharmaceuticals in environmental water matrices Comparison between polyurethane and polydimethylsiloxane polymeric phases.
Topics: Chromatography, High Pressure Liquid; Diclofenac; Dimethylpolysiloxanes; Gemfibrozil; Ibuprofen; Mefenamic Acid; Naproxen; Polyurethanes; Reproducibility of Results; Water Pollutants, Chemical; Water Purification | 2008 |
Removal of selected pharmaceuticals by chlorination, coagulation-sedimentation and powdered activated carbon treatment.
Topics: Antipyrine; Charcoal; Clofibric Acid; Diclofenac; Fenoprofen; Gemfibrozil; Halogenation; Ibuprofen; Indomethacin; Ketoprofen; Naproxen; Water Pollutants, Chemical; Water Purification; Water Supply | 2008 |
Occurrence, temporal evolution and risk assessment of pharmaceutically active compounds in Doñana Park (Spain).
Topics: Environmental Monitoring; Estrogens; Fresh Water; Gemfibrozil; Ibuprofen; Industrial Waste; Naproxen; Pharmaceutical Preparations; Propranolol; Risk Assessment; Rivers; Seasons; Spain; Time Factors | 2010 |
[Amorphous form in pharmaceutical technological research].
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chlorhexidine; Clopidogrel; Dihydropyridines; Gemfibrozil; Glass; Ibuprofen; Loratadine; Meloxicam; Pharmaceutical Preparations; Piroxicam; Sorbitol; Technology, Pharmaceutical; Thiazines; Thiazoles; Ticlopidine | 2011 |
Can pharmaceuticals interfere with the synthesis of active androgens in male fish? An in vitro study.
Topics: Androgens; Animals; Anti-Inflammatory Agents; Antidepressive Agents; Biomarkers; Carps; Clofibrate; Clofibric Acid; Diclofenac; Fibric Acids; Fluoxetine; Gemfibrozil; Ibuprofen; Male; Steroid 11-beta-Hydroxylase; Steroid 17-alpha-Hydroxylase; Testis; Water Pollutants, Chemical | 2011 |
Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.
Topics: Animals; Atrazine; Benzhydryl Compounds; Carbamazepine; Diclofenac; Environmental Monitoring; Fishes; Fluoxetine; Gemfibrozil; Ibuprofen; Naproxen; Phenols; Solid Phase Extraction; Solid Phase Microextraction; Waste Disposal, Fluid; Water Pollutants, Chemical | 2011 |
The role of microbial adaptation and biodegradable dissolved organic carbon on the attenuation of trace organic chemicals during groundwater recharge.
Topics: 2-Methyl-4-chlorophenoxyacetic Acid; 2,4-Dichlorophenoxyacetic Acid; Adaptation, Physiological; Biodegradation, Environmental; Carbon; Clofibric Acid; Gemfibrozil; Groundwater; Ibuprofen; Ketoprofen; Naproxen; Organic Chemicals; Soil Microbiology; Water Microbiology; Water Pollutants, Chemical; Water Purification | 2012 |
Occurrence and distribution of pharmaceutically active and endocrine disrupting compounds in Singapore's marine environment: influence of hydrodynamics and physical-chemical properties.
Topics: Carbamazepine; Endocrine Disruptors; Environmental Monitoring; Gemfibrozil; Hydrodynamics; Ibuprofen; Pharmaceutical Preparations; Seawater; Singapore; Triclosan; Waste Disposal Facilities; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2013 |
Circular dichroism spectroscopic detection of ligand binding induced subdomain IB specific structural adjustment of human serum albumin.
Topics: Bile Acids and Salts; Binding Sites; Circular Dichroism; Dehydroepiandrosterone Sulfate; Fatty Acids; Gemfibrozil; Humans; Ibuprofen; Ligands; Protein Conformation; Protein Structure, Tertiary; Saponins; Serum Albumin; Tyrosine | 2013 |
Removal of acidic pharmaceuticals within a nitrifying recirculating biofilter.
Topics: Adsorption; Bacteria; Biofilms; Diclofenac; DNA, Bacterial; Filtration; Gemfibrozil; Genes, Bacterial; Ibuprofen; Naproxen; Nitrification; Waste Disposal, Fluid; Water Pollutants, Chemical | 2014 |
Occurrence of selected pharmaceuticals in the principal sewage treatment plants in Rome (Italy) and in the receiving surface waters.
Topics: Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Estrone; Gemfibrozil; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Rome; Seasons; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical | 2015 |
Parallel artificial liquid membrane extraction of acidic drugs from human plasma.
Topics: Calibration; Chromatography, High Pressure Liquid; Diclofenac; Equipment Design; Flurbiprofen; Gemfibrozil; Humans; Hydrogen-Ion Concentration; Ibuprofen; Ketoprofen; Liquid-Liquid Extraction; Membranes, Artificial; Pharmaceutical Preparations; Polypropylenes; Polyvinyls | 2015 |
Transport behavior of the pharmaceutical compounds carbamazepine, sulfamethoxazole, gemfibrozil, ibuprofen, and naproxen, and the lifestyle drug caffeine, in saturated laboratory columns.
Topics: Caffeine; Carbamazepine; Filtration; Gemfibrozil; Ibuprofen; Naproxen; Ontario; Silicon Dioxide; Sulfamethoxazole; Water Pollutants, Chemical | 2017 |
Multimarker Responses of Zebrafish to the Effect of Ibuprofen and Gemfibrozil in Environmentally Relevant Concentrations.
Topics: Animals; Gemfibrozil; Ibuprofen; Oxidative Stress; Pharmaceutical Preparations; Water Pollutants, Chemical; Zebrafish | 2022 |
Pharmaceuticals, natural and synthetic hormones and phenols in sediments from an eutrophic estuary, Jurujuba Sound, Guanabara Bay, Brazil.
Topics: Bays; Brazil; Diclofenac; Endocrine Disruptors; Environmental Monitoring; Estradiol; Estriol; Estrogens; Estrone; Estuaries; Gemfibrozil; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenols; Water Pollutants, Chemical | 2022 |