gemfibrozil and d-alpha tocopherol

gemfibrozil has been researched along with d-alpha tocopherol in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.76)18.7374
1990's3 (14.29)18.2507
2000's8 (38.10)29.6817
2010's9 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aizawa, Y; Fujita, T; Hasegawa, K; Horikoshi, H; Kanai, T; Kurumada, T; Yoshioka, T1
Bhatia, G; Rosaiah, JN; Sashidhara, KV; Saxena, JK1
Bhatia, G; Khan, MM; Khanna, AK; Kumar, A; Sashidhara, KV; Saxena, JK1
Bhatia, G; Ghosh, S; Khan, MM; Khanna, AK; Misra, AK1
Bhatia, G; Kumar, A; Kumar, M; Maurya, RA; Sharma, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Bhatia, G; Khanna, AK; Kumar, A; Rosaiah, JN; Sashidhara, KV1
Bhatia, G; Khanna, AK; Kumar, A; Kumar, M; Sashidhara, KV; Sonkar, R1
Bhatia, G; Chaturvedi, U; Khanna, AK; Narender, T; Rajendar, K; Sarkar, S; Singh, VK1
Bhatia, G; Dodda, RP; Khanna, AK; Palnati, GR; Sashidhara, KV; Sonkar, R1
Bhatia, G; Modukuri, RK; Rao, KB; Sashidhara, KV; Sonkar, R1
Bhatia, G; Pandeti, S; Shukla, A; Sonkar, R; Tadigoppula, N1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Aberg, F; Angelin, B; Appelkvist, EL; Bröijersén, A; Dallner, G; Eriksson, M; Hjemdahl, P1
Ayaori, M; Ishikawa, T; Ito, T; Nakamura, H; Shige, H; Suzukawa, M; Yoshida, H1
Bellamy, FD; Chaput, E; Edgar, AD; Maubrou-Sanchez, D1
Cramb, R1
Bredie, SJ; de Graaf, J; Demacker, PN; Kastelein, JJ; Stalenhoef, AF; Wittekoek, ME1
Cunningham, ML; Glauert, HP; O'Brien, ML; Spear, BT; Twaroski, TP1
Chen, MF; Hsu, HC; Lee, YT; Wang, TD; Yeh, HT1
Inal, M; Ozdemir, F; Sutken, E1

Reviews

1 review(s) available for gemfibrozil and d-alpha tocopherol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for gemfibrozil and d-alpha tocopherol

ArticleYear
Gemfibrozil-induced decrease in serum ubiquinone and alpha- and gamma-tocopherol levels in men with combined hyperlipidaemia.
    European journal of clinical investigation, 1998, Volume: 28, Issue:3

    Topics: Adult; Aged; Antioxidants; Apolipoproteins; Case-Control Studies; Coronary Disease; Cross-Over Studies; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged; Ubiquinone; Vitamin E

1998
Beneficial effect of gemfibrozil on the chemical composition and oxidative susceptibility of low density lipoprotein: a randomized, double-blind, placebo-controlled study.
    Atherosclerosis, 1998, Volume: 139, Issue:1

    Topics: Adult; Aged; Apolipoproteins; Arteriosclerosis; Double-Blind Method; Fatty Acids, Nonesterified; Female; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxides; Lipids; Lipoproteins, LDL; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Vitamin E

1998
The effect of concentrated n-3 fatty acids versus gemfibrozil on plasma lipoproteins, low density lipoprotein heterogeneity and oxidizability in patients with hypertriglyceridemia.
    Atherosclerosis, 2000, Volume: 153, Issue:1

    Topics: Adult; Double-Blind Method; Fatty Acids; Fatty Acids, Omega-3; Gemfibrozil; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Lipids; Lipoproteins; Lipoproteins, LDL; Middle Aged; Osmolar Concentration; Oxidation-Reduction; Vitamin E

2000
Gemfibrozil treatment potentiates oxidative resistance of high-density lipoprotein in hypertriglyceridemic patients.
    European journal of clinical investigation, 2001, Volume: 31, Issue:8

    Topics: Administration, Oral; Adult; Cholesterol, HDL; Cholesterol, LDL; Female; Gemfibrozil; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Lipid Peroxidation; Lipoproteins, VLDL; Male; Middle Aged; Oxidation-Reduction; Thiobarbituric Acid Reactive Substances; Time Factors; Vitamin E

2001
Effects of vitamin E and gemfibrozil on lipid profiles, lipid peroxidation and antioxidant status in the elderly and young hyperlipidemic subjects.
    Saudi medical journal, 2006, Volume: 27, Issue:4

    Topics: Adult; Age Factors; Aged; Antioxidants; Female; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Lipids; Male; Vitamin E

2006

Other Studies

15 other study(ies) available for gemfibrozil and d-alpha tocopherol

ArticleYear
Studies on hindered phenols and analogues. 1. Hypolipidemic and hypoglycemic agents with ability to inhibit lipid peroxidation.
    Journal of medicinal chemistry, 1989, Volume: 32, Issue:2

    Topics: Animals; Hypoglycemic Agents; Hypolipidemic Agents; Lipid Peroxidation; Male; Mice; Mice, Inbred BALB C; Phenols; Rats; Structure-Activity Relationship

1989
Novel keto-enamine Schiffs bases from 7-hydroxy-4-methyl-2-oxo-2H-benzo[h] chromene-8,10-dicarbaldehyde as potential antidyslipidemic and antioxidant agents.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:11

    Topics: Amines; Animals; Antioxidants; Coumarins; Female; Free Radicals; Hyperlipidemias; Hypolipidemic Agents; Magnetic Resonance Spectroscopy; Molecular Structure; Rats; Schiff Bases

2008
Antidyslipidemic and antioxidative activities of 8-hydroxyquinoline derived novel keto-enamine Schiffs bases.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Amines; Animals; Antioxidants; Dyslipidemias; Fluorescence; Heparin; Hydroxyl Radical; Hydroxyquinolines; Lipid Metabolism; Male; Rats; Schiff Bases; Superoxides

2009
Syntheses and evaluation of glucosyl aryl thiosemicarbazide and glucosyl thiosemicarbazone derivatives as antioxidant and anti-dyslipidemic agents.
    Bioorganic & medicinal chemistry letters, 2009, Jan-15, Volume: 19, Issue:2

    Topics: Animals; Antioxidants; Drug Evaluation, Preclinical; Dyslipidemias; Hypolipidemic Agents; Rats; Semicarbazides; Thiosemicarbazones

2009
Synthesis and biological evaluation of N-aryl-1,4-dihydropyridines as novel antidyslipidemic and antioxidant agents.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:2

    Topics: Animals; Catalysis; Dihydropyridines; Free Radical Scavengers; Hypolipidemic Agents; Iodine; Lipids; Lipolysis; Male; Rats

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Synthesis of novel benzocoumarin derivatives as lipid lowering agents.
    Bioorganic & medicinal chemistry letters, 2010, May-15, Volume: 20, Issue:10

    Topics: Animals; Coumarins; Hyperlipidemias; Hypolipidemic Agents; Rats; Structure-Activity Relationship

2010
Novel coumarin derivatives as potential antidyslipidemic agents.
    Bioorganic & medicinal chemistry letters, 2010, Jul-15, Volume: 20, Issue:14

    Topics: Coumarins; Dyslipidemias; Humans

2010
Synthesis of novel N-(2-hydroxy-2-p-tolylethyl)-amide and N-(2-oxo-2-p-tolylethyl)-amide derivatives and their antidyslipidemic and antioxidant activity.
    Bioorganic & medicinal chemistry letters, 2011, Nov-01, Volume: 21, Issue:21

    Topics: Animals; Antioxidants; Hypolipidemic Agents; Male; Rats; Toluene

2011
Discovery of amide based fibrates as possible antidyslipidemic and antioxidant agents.
    European journal of medicinal chemistry, 2012, Volume: 57

    Topics: Amides; Animals; Antioxidants; Enzyme Activation; Fibric Acids; Free Radicals; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Lipoprotein Lipase; Male; Polyethylene Glycols; Rats; Structure-Activity Relationship

2012
Hybrid benzofuran-bisindole derivatives: new prototypes with promising anti-hyperlipidemic activities.
    European journal of medicinal chemistry, 2013, Volume: 68

    Topics: Animals; Antioxidants; Benzofurans; Cholesterol; Enzyme Activation; Hypolipidemic Agents; Indoles; Lipolysis; Male; Molecular Structure; Phosphatidylcholine-Sterol O-Acyltransferase; Phospholipids; Rats; Triglycerides

2013
Synthesis of new andrographolide derivatives and evaluation of their antidyslipidemic, LDL-oxidation and antioxidant activity.
    European journal of medicinal chemistry, 2013, Volume: 69

    Topics: Animals; Antioxidants; Disease Models, Animal; Diterpenes; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins, LDL; Male; Molecular Structure; Oxidation-Reduction; Rats; Rats, Inbred Strains

2013
Fenofibrate protects lipoproteins from lipid peroxidation: synergistic interaction with alpha-tocopherol.
    Lipids, 1999, Volume: 34, Issue:5

    Topics: Animals; Bezafibrate; Drug Synergism; Fenofibrate; Gemfibrozil; Hypolipidemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Rats; Rats, Sprague-Dawley; Vitamin E

1999
Therapy and clinical trials.
    Current opinion in lipidology, 2000, Volume: 11, Issue:2

    Topics: Coronary Disease; Endothelium, Vascular; Fatty Acids, Omega-3; Fatty Acids, Unsaturated; Gemfibrozil; Humans; Triglycerides; Vitamin E

2000
Effects of peroxisome proliferators on antioxidant enzymes and antioxidant vitamins in rats and hamsters.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 60, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Cricetinae; Dibutyl Phthalate; Gemfibrozil; Liver; Male; Mesocricetus; NAD(P)H Dehydrogenase (Quinone); Peroxisome Proliferators; Pyrimidines; Rats; Rats, Sprague-Dawley; Species Specificity; Superoxide Dismutase; Vitamin E

2001