gemfibrozil has been researched along with clopidogrel in 10 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 2 (20.00) | 29.6817 |
2010's | 7 (70.00) | 24.3611 |
2020's | 1 (10.00) | 2.80 |
Authors | Studies |
---|---|
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Ballard, TE; Henderson, JL; Kalgutkar, AS; Obach, RS; Orr, ST; Ripp, SL; Scott, DO; Sun, H | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Dalvie, D; Fu, Y; Khojasteh, SC; Ma, Y; Zhang, D | 1 |
Gami, A | 1 |
Arnaout, A; Malcolm, J; Sigal, R | 1 |
Jójártné, LO; Mártha, C; Szabóné, RP | 1 |
Backman, JT; Itkonen, MK; Neuvonen, M; Neuvonen, PJ; Niemi, M; Tornio, A | 1 |
Backman, JT; Evangelista, EA; Filppula, AM; Kahma, H; Launiainen, T; Neuvonen, M; Totah, RA; Viinamäki, J | 1 |
Shah, MB | 1 |
6 review(s) available for gemfibrozil and clopidogrel
Article | Year |
---|---|
Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks.
Topics: Animals; Apoproteins; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Drug Interactions; Heme; Humans; Models, Biological; Pharmacokinetics; Structure-Activity Relationship; Time Factors | 2012 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Glucuronides as Potential Anionic Substrates of Human Cytochrome P450 2C8 (CYP2C8).
Topics: Anions; Binding Sites; Cytochrome P-450 CYP2C8; Drug Interactions; Glucuronides; Humans; Ligands | 2017 |
Secondary prevention of ischaemic cardiac events.
Topics: Adrenergic beta-Antagonists; Angioplasty, Balloon, Coronary; Angiotensin-Converting Enzyme Inhibitors; Anticoagulants; Antihypertensive Agents; Aspirin; Clopidogrel; Coronary Artery Bypass; Diet; Drug Therapy, Combination; Estrogen Replacement Therapy; Exercise; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardial Ischemia; Platelet Aggregation Inhibitors; Smoking Cessation; Ticlopidine | 2006 |
Prevention of cardiovascular events in diabetes.
Topics: Angioplasty, Balloon; Antihypertensive Agents; Aspirin; Bezafibrate; Cardiovascular Diseases; Clopidogrel; Diabetic Angiopathies; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Smoking Cessation; Ticlopidine | 2006 |
Inhibition of CYP2C8 by Acyl Glucuronides of Gemfibrozil and Clopidogrel: Pharmacological Significance, Progress and Challenges.
Topics: Cholesterol; Clopidogrel; Cytochrome P-450 CYP2C8; Gemfibrozil; Glucuronides; Heme; Platelet Aggregation Inhibitors; Triglycerides | 2022 |
4 other study(ies) available for gemfibrozil and clopidogrel
Article | Year |
---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
[Amorphous form in pharmaceutical technological research].
Topics: Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Chlorhexidine; Clopidogrel; Dihydropyridines; Gemfibrozil; Glass; Ibuprofen; Loratadine; Meloxicam; Pharmaceutical Preparations; Piroxicam; Sorbitol; Technology, Pharmaceutical; Thiazines; Thiazoles; Ticlopidine | 2011 |
Clopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans.
Topics: Adult; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Biotransformation; Clopidogrel; Cross-Over Studies; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C8 Inhibitors; Drug Interactions; Female; Gemfibrozil; Genotype; Glucuronides; Humans; Hypolipidemic Agents; Loratadine; Male; Young Adult | 2019 |
Critical Differences between Enzyme Sources in Sensitivity to Detect Time-Dependent Inactivation of CYP2C8.
Topics: Amiodarone; Clopidogrel; Cytochrome P-450 CYP2C8; Gemfibrozil; Glucuronides; Humans; Kinetics; Microsomes, Liver; Phenelzine; Sensitivity and Specificity | 2019 |