gemfibrozil and cerivastatin

gemfibrozil has been researched along with cerivastatin in 48 studies

Research

Studies (48)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	3 (6.25)	18.2507
2000's	40 (83.33)	29.6817
2010's	5 (10.42)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bilter, GK; Dias, J; Huang, Z; Keon, BH; Lamerdin, J; MacDonald, ML; Michnick, SW; Minami, T; Owens, S; Shang, Z; Westwick, JK; Yu, H	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Farnier, M	1
Carper, BG; Kindred, LH; Pogson, GW	1
Dujovne, CA; Guyton, JR; Illingworth, DR	1
Bermingham, RP; Nowak, DP; Scalley, RD; Smart, ML; Whitsitt, TB	1
Boran, M; Gökçe, V; Koçak, B; Korkmaz, S; Ozdemir, O; Uzun, Y	1
Alexandridis, G; Elisaf, MS; Pappas, GA	1
Black, DM	1
Coletta, S; Corpolongo, A; d'Ettorre, G; Forcina, G; Lichtner, M; Mastroianni, CM; Vullo, V	1
Banga, JD; Dallinga-Thie, GM; Eeltink, H; Erkelens, DW; Rabelink, TJ; Stroes, ES; Twickler, MB; Wilmink, HW	1
Lan, IW; Tomlinson, B	1
Gómez Rodríguez, N; Martín Joven, A; Posada García, FJ; Vascónez Espinosa, F	1
Lau, TK; Leachman, DR; Lufschanowski, R	1
Hamilton-Craig, I	1
Breuer, HW	1
Charatan, F	1
SoRelle, R	1
de Arriba Méndez, JJ; Gómez Merino, E; Sáez Barcelona, JA; Sáez Méndez, L	1
Wooltorton, E	1
Bruno-Joyce, J; Dugas, JM; MacCausland, OE	1
Gázquez Pérez, I; Matas Hoces, A; Tormo Molina, J	1
Hendriks, F; Kooman, JP; van der Sande, FM	1
Bosch Rovira, T; Forteza-Rey, J; Llompart Pou, JA	1
Calvo, B; Monferrer, R; Roca, B	1
Alos Manrique, C; Marsà Carretero, M; Valles Callol, JA	1
Bairaktari, E; Elisaf, M; Liamis, G; Psihogios, N; Seferiadis, K; Tsolas, O	1
Fernández, MY; González, A; León, ME; SantaCruz, PL	1
Flomenbaum, M; Hoffman, RS; Su, M	1
Kind, AH; McBride, PE; Zakowski, LJ	1
Backman, JT; Neuvonen, M; Neuvonen, PJ; Wang, JS; Wen, X	1
Backman, JT; Kyrklund, C; Neuvonen, M; Neuvonen, PJ	1
Bult, J; Keehr, LM; Sai, TT; Schiff, GD	1
Arenas, J; Bermejo, F; Börnstein, B; Cabello, A; Calvo, P; Campos, Y; del Hoyo, P; Fernández, V; Fernández-Moreno, MA; García, A; Garesse, R; Martín, MA; Martínez-Salio, A; Molina, JA; Moreno, T	1
Fujino, H; Hirano, M; Kojima, J; Shimada, S; Tsunenari, Y; Yamada, I	1
Benitez, J; Carrillo, JA; Gervasini, G; Morera, T	1
Hirano, M; Sato, H; Shitara, Y; Sugiyama, Y	1
Eichelbaum, M; Fromm, MF; Hofmann, U; Kivistö, KT; Luippold, G; Niemi, M; Rekersbrink, S; Schneider, S; Schwab, M; Zukunft, J	1
Furberg, CD; Psaty, BM; Ray, WA; Weiss, NS	1
Strom, BL	1
Piorkowski, JD	1
Balice, M; Chironi, G; Del-Pino, M; Gariepy, J; Levenson, J; Simon, A	1
Hasegawa, R; Hirata-Koizumi, M; Miyake, S; Saito, M	1
Kim, SJ; Sugiyama, Y; Toshimoto, K; Yao, Y; Yoshikado, T	1

Reviews

6 review(s) available for gemfibrozil and cerivastatin

Article	Year
Statins in children: what do we know and what do we need to do? Current atherosclerosis reports, 2001, Volume: 3, Issue:1 Topics: Atorvastatin; Bezafibrate; Child; Child Welfare; Cost-Benefit Analysis; Drug Approval; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Pyridines; Pyrroles; Simvastatin	2001
Severe rhabdomyolysis associated with the cerivastin-gemfibrozil combination therapy: report of a case. Texas Heart Institute journal, 2001, Volume: 28, Issue:2 Topics: Aged; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Pyridines; Rhabdomyolysis; Severity of Illness Index	2001
Hypertriglyceridemia: a review of clinical relevance and treatment options: focus on cerivastatin. Current medical research and opinion, 2001, Volume: 17, Issue:1 Topics: Atorvastatin; Coronary Disease; Drug Therapy, Combination; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Hypolipidemic Agents; Niacin; Pyridines; Pyrroles; Risk Factors; Triglycerides	2001
[Severe rhabdomyolysis associated with cerivastatin and gemfibrozil]. Medicina clinica, 2001, Sep-15, Volume: 117, Issue:7 Topics: Female; Gemfibrozil; Humans; Hypolipidemic Agents; Middle Aged; Pyridines; Rhabdomyolysis	2001
Severe rhabdomyolysis and cerivastatin-gemfibrozil combination therapy. The Annals of pharmacotherapy, 2002, Volume: 36, Issue:4 Topics: Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Male; Middle Aged; Pyridines; Rhabdomyolysis	2002
Potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysis. JAMA, 2004, Dec-01, Volume: 292, Issue:21 Topics: Adverse Drug Reaction Reporting Systems; Conflict of Interest; Drug Industry; Drug Interactions; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Pyridines; Rhabdomyolysis; Risk; United States; United States Food and Drug Administration	2004

Trials

3 trial(s) available for gemfibrozil and cerivastatin

Article	Year
Cerivastatin in the treatment of mixed hyperlipidemia: the RIGHT study. The Cerivastatin Study Group. Cerivastatin Gemfibrozil Hyperlipidemia Treatment. The American journal of cardiology, 1998, Aug-27, Volume: 82, Issue:4B Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cholesterol, HDL; Cholesterol, VLDL; Cholestyramine Resin; Female; Follow-Up Studies; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type V; Hypolipidemic Agents; Male; Middle Aged; Pyridines; Safety; Treatment Outcome; Triglycerides	1998
Effect of statin versus fibrate on postprandial endothelial dysfunction: role of remnant-like particles. Cardiovascular research, 2001, Volume: 50, Issue:3 Topics: Adolescent; Adult; Cross-Over Studies; Dietary Fats; Double-Blind Method; Endothelium, Vascular; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipids; Male; Postprandial Period; Pyridines; Vasodilation	2001
Gemfibrozil greatly increases plasma concentrations of cerivastatin. Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:6 Topics: Administration, Oral; Adult; Area Under Curve; Cross-Over Studies; Double-Blind Method; Drug Interactions; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Pyridines; Reference Values; Rhabdomyolysis	2002

Other Studies

39 other study(ies) available for gemfibrozil and cerivastatin

Article	Year
Identifying off-target effects and hidden phenotypes of drugs in human cells. Nature chemical biology, 2006, Volume: 2, Issue:6 Topics: Bacterial Proteins; Cell Line; Cell Proliferation; Cluster Analysis; Drug Design; Drug Evaluation, Preclinical; Genetics; Humans; Luminescent Proteins; Molecular Structure; Phenotype; Recombinant Fusion Proteins; Signal Transduction; Structure-Activity Relationship	2006
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy. The American journal of cardiology, 1999, Apr-01, Volume: 83, Issue:7 Topics: Aged; Drug Interactions; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Pyridines; Renal Insufficiency; Rhabdomyolysis	1999
Dual hepatic metabolism of cerivastatin--clarifications. The American journal of cardiology, 1999, Aug-15, Volume: 84, Issue:4 Topics: Aged; Drug Synergism; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Liver; Pyridines; Rhabdomyolysis; Stereoisomerism	1999
Rhabdomyolysis in a patient receiving the combination of cerivastatin and gemfibrozil. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2000, Mar-01, Volume: 57, Issue:5 Topics: Certification; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Middle Aged; Pharmacists; Pyridines; Rhabdomyolysis	2000
A case with severe rhabdomyolysis and renal failure associated with cerivastatin-gemfibrozil combination therapy--a case report. Angiology, 2000, Volume: 51, Issue:8 Topics: Diabetes Mellitus; Drug Interactions; Drug Therapy, Combination; Electrocardiography; Fatal Outcome; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Myocardial Ischemia; Pyridines; Renal Dialysis; Renal Insufficiency; Rhabdomyolysis	2000
Rhabdomyolysis due to combination therapy with cerivastatin and gemfibrozil. The American journal of medicine, 2000, Aug-15, Volume: 109, Issue:3 Topics: Aged; Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Pyridines; Rhabdomyolysis	2000
Rhabdomyolysis after cerivastatin-gemfibrozil therapy in an HIV-infected patient with protease inhibitor-related hyperlipidemia. AIDS (London, England), 2001, Apr-13, Volume: 15, Issue:6 Topics: Acute Kidney Injury; Drug Therapy, Combination; Gemfibrozil; HIV Infections; HIV Protease Inhibitors; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Pyridines; Rhabdomyolysis	2001
Combination therapy with cerivastatin and gemfibrozil causing rhabdomyolysis: is the interaction predictable? The American journal of medicine, 2001, Jun-01, Volume: 110, Issue:8 Topics: Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Pyridines; Rhabdomyolysis	2001
[Rhabdomyolysis complicated with acute renal insufficiency in a patient treated with gemfibrozil and cerivastatin]. Revista clinica espanola, 2001, Volume: 201, Issue:4 Topics: Acute Kidney Injury; Aged; Drug Interactions; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Pyridines; Rhabdomyolysis	2001
Normocholesterolaemic dysslipidaemia: is there a role for fibrates? The Medical journal of Australia, 2001, Jun-04, Volume: 174, Issue:11 Topics: Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Pyridines; Treatment Outcome; Triglycerides	2001
Bayer decides to withdraw cholesterol lowering drug. BMJ (Clinical research ed.), 2001, Aug-18, Volume: 323, Issue:7309 Topics: Aged; Anticholesteremic Agents; Drug and Narcotic Control; Drug Therapy, Combination; Gemfibrozil; Humans; Product Surveillance, Postmarketing; Pyridines; Rhabdomyolysis	2001
Baycol withdrawn from market. Circulation, 2001, Aug-21, Volume: 104, Issue:8 Topics: Anticholesteremic Agents; Dose-Response Relationship, Drug; Drug and Narcotic Control; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Product Surveillance, Postmarketing; Pyridines; Rhabdomyolysis; United States; United States Food and Drug Administration	2001
Bayer pulls cerivastatin (Baycol) from market. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2001, Sep-04, Volume: 165, Issue:5 Topics: Canada; Drug Industry; Drug Interactions; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Pyridines; Rhabdomyolysis; United States; United States Food and Drug Administration	2001
Cerivastatin and gemfibrozil-associated rhabdomyolysis. The Annals of pharmacotherapy, 2001, Volume: 35, Issue:9 Topics: Aged; Aged, 80 and over; Creatine Kinase; Drug Interactions; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Middle Aged; Pyridines; Rhabdomyolysis	2001
[Cerivastatin and gemfibrozil: a dangerous combination]. Atencion primaria, 2001, Oct-15, Volume: 28, Issue:6 Topics: Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Middle Aged; Pyridines; Rhabdomyolysis	2001
Massive rhabdomyolysis and life threatening hyperkalaemia in a patient with the combination of cerivastatin and gemfibrozil. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2001, Volume: 16, Issue:12 Topics: Aged; Chest Pain; Drug Combinations; Electrocardiography; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperkalemia; Hypolipidemic Agents; Muscle, Skeletal; Pain; Pyridines; Renal Dialysis; Rhabdomyolysis	2001
[Rhabdomyolysis associated with combined treatment of cerivastatin and gemfibrozil]. Revista clinica espanola, 2001, Volume: 201, Issue:12 Topics: Drug Interactions; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Middle Aged; Pyridines; Rhabdomyolysis	2001
Statin stories. Diabetes, obesity & metabolism, 2002, Volume: 4, Issue:2 Topics: Drug Interactions; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyridines; Rhabdomyolysis	2002
Rhabdomyolysis associated with cerivastatin plus gemfibrozil combined regimen. The British journal of general practice : the journal of the Royal College of General Practitioners, 2002, Volume: 52, Issue:476 Topics: Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Middle Aged; Pyridines; Rhabdomyolysis	2002
Rhabdomyolysis-related renal tubular damage studied by proton nuclear magnetic resonance spectroscopy of urine. Clinical chemistry, 2002, Volume: 48, Issue:7 Topics: beta 2-Microglobulin; Biomarkers; Drug Therapy, Combination; Gemfibrozil; Humans; Hyperlipidemias; Kidney Diseases; Kidney Tubules; Magnetic Resonance Spectroscopy; Male; Membrane Glycoproteins; Pyridines; Rhabdomyolysis; Trypsin Inhibitor, Kunitz Soybean	2002
[Rhabdomyolysis, acute renal failure and use of cerivastatin combined with gemfibrozil. New evidence]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2002, Volume: 22, Issue:3 Topics: Acute Kidney Injury; Aged; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Pyridines; Rhabdomyolysis	2002
Cerivastatin and gemfibrozil-induced cardiac rhabdomyolysis. The American journal of forensic medicine and pathology, 2002, Volume: 23, Issue:3 Topics: Cardiomyopathies; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Male; Middle Aged; Pyridines; Rhabdomyolysis	2002
Rhabdomyolysis from the combination of a statin and gemfibrozil: an uncommon but serious adverse reaction. WMJ : official publication of the State Medical Society of Wisconsin, 2002, Volume: 101, Issue:7 Topics: Drug Therapy, Combination; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Middle Aged; Pyridines; Rhabdomyolysis	2002
Gemfibrozil inhibits CYP2C8-mediated cerivastatin metabolism in human liver microsomes. Drug metabolism and disposition: the biological fate of chemicals, 2002, Volume: 30, Issue:12 Topics: Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C8; Dose-Response Relationship, Drug; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Microsomes, Liver; Pyridines	2002
High rates of adverse effects and patient unawareness of withdrawn lipid-lowering drug combination in a public hospital clinic. Pharmacoepidemiology and drug safety, 2002, Volume: 11, Issue:8 Topics: Creatine Kinase; Drug Interactions; Gemfibrozil; Hospitals, Public; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Muscle Weakness; Pain; Patient Education as Topic; Pyridines	2002
Myoglobinuria and COX deficiency in a patient taking cerivastatin and gemfibrozil. Neurology, 2003, Jan-14, Volume: 60, Issue:1 Topics: Aged; Biopsy; Cytochrome-c Oxidase Deficiency; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Muscle Fibers, Fast-Twitch; Muscle Weakness; Muscle, Skeletal; Myoglobinuria; Pain; Pyridines	2003
Interaction between fibrates and statins--metabolic interactions with gemfibrozil. Drug metabolism and drug interactions, 2003, Volume: 19, Issue:3 Topics: Atorvastatin; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Microsomes, Liver; Pyridines; Pyrroles; Quinolines	2003
Early detection of drug interactions utilizing a computerized drug prescription handling system-focus on cerivastatin-gemfibrozil. European journal of clinical pharmacology, 2004, Volume: 59, Issue:12 Topics: Drug Interactions; Drug Prescriptions; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Medical Records Systems, Computerized; Practice Patterns, Physicians'; Pyridines; Retrospective Studies; Rhabdomyolysis; Spain	2004
Gemfibrozil and its glucuronide inhibit the organic anion transporting polypeptide 2 (OATP2/OATP1B1:SLC21A6)-mediated hepatic uptake and CYP2C8-mediated metabolism of cerivastatin: analysis of the mechanism of the clinically relevant drug-drug interaction The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:1 Topics: Aryl Hydrocarbon Hydroxylases; Blood Proteins; Carbon Radioisotopes; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Gemfibrozil; Glucuronates; Hepatocytes; Humans; Hypolipidemic Agents; Liver; Liver-Specific Organic Anion Transporter 1; Pyridines	2004
Characterisation of cerivastatin as a P-glycoprotein substrate: studies in P-glycoprotein-expressing cell monolayers and mdr1a/b knock-out mice. Naunyn-Schmiedeberg's archives of pharmacology, 2004, Volume: 370, Issue:2 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport, Active; Brain; Cell Line; Drug Interactions; Gemfibrozil; Humans; Hypolipidemic Agents; Kidney; Liver; Mice; Mice, Knockout; Muscle, Skeletal; Pyridines; Time Factors; Tissue Distribution	2004
Potential for conflict of interest in the evaluation of suspected adverse drug reactions: a counterpoint. JAMA, 2004, Dec-01, Volume: 292, Issue:21 Topics: Adverse Drug Reaction Reporting Systems; Conflict of Interest; Drug Approval; Drug Industry; Drug Interactions; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Pyridines; Rhabdomyolysis; Risk; United States; United States Food and Drug Administration	2004
Bayer's response to "potential for conflict of interest in the evaluation of suspected adverse drug reactions: use of cerivastatin and risk of rhabdomyolysis". JAMA, 2004, Dec-01, Volume: 292, Issue:21 Topics: Adverse Drug Reaction Reporting Systems; Conflict of Interest; Drug Approval; Drug Industry; Drug Interactions; Drug Labeling; Expert Testimony; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Liability, Legal; Pyridines; Rhabdomyolysis; Risk; United States; United States Food and Drug Administration	2004
Differential associations of statin and fibrate treatment with carotid arterial remodeling. American journal of hypertension, 2005, Volume: 18, Issue:11 Topics: Adult; Atorvastatin; Bezafibrate; Body Mass Index; Carotid Arteries; Cholesterol, HDL; Clofibric Acid; Cohort Studies; Dyslipidemias; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fibric Acids; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Male; Middle Aged; Multivariate Analysis; Pravastatin; Pyridines; Pyrroles; Risk Factors; Simvastatin; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography	2005
[Withdrawal of cerivastatin revealed a flaw of post-marketing surveillance system in the United States]. Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences, 2005, Issue:123 Topics: Adverse Drug Reaction Reporting Systems; Consumer Product Safety; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Approval; Drug Interactions; Drug Therapy, Combination; Gemfibrozil; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Product Surveillance, Postmarketing; Pyridines; Rhabdomyolysis; Risk; United States; United States Food and Drug Administration	2005
Quantitative Analysis of Complex Drug-Drug Interactions between Cerivastatin and Metabolism/Transport Inhibitors Using Physiologically Based Pharmacokinetic Modeling. Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:7 Topics: Biological Transport; Cyclosporine; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Gemfibrozil; Glucuronides; Hepatocytes; Humans; Liver; Liver-Specific Organic Anion Transporter 1; Models, Biological; Pyridines	2018