gemfibrozil and carbamazepine

gemfibrozil has been researched along with carbamazepine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (18.18)29.6817
2010's25 (75.76)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Doman, TN; McGovern, SL; Seidler, J; Shoichet, BK1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Paxéus, N1
Blaise, C; Fournier, M; Gagné, F; Hansen, PD1
Binelli, A; Parolini, M; Provini, A; Quinn, B1
Gunsch, CK; Wang, S1
Badruzzaman, M; Eaton, A; Haghani, AW; Jacangelo, JG; Oppenheimer, J1
Bragg, LM; Dixon, G; Oakes, KD; Pawliszyn, J; Servos, MR; Wang, S1
Alonso, E; Aparicio, I; Camacho-Muñoz, MA; Martín, J; Santos, JL1
Coleman, HM; Khan, SJ; Le-Clech, P; Stuetz, RM; Trinh, T; van den Akker, B1
Liu, Y; Wu, L; Yu, Y1
Bayen, S; Desai, MM; Kelly, BC; Ooi, SK; Zhang, H1
Fang, MD; Jiang, JJ; Lee, CL1
Balshine, S; Galus, M; Lai, A; Rangarajan, S; Shaya, L; Wilson, JY1
Prosser, RS; Sibley, PK; Trapp, S1
Ademollo, N; Capri, S; Patrolecco, L1
Groza, LG; Hebig, KH; Ptacek, CJ; Sabourin, MJ; Scheytt, TJ1
Fraz, S; Hammill, KM; Lee, AH; Wilson, JY1
Fraz, S; Lee, AH; Wilson, JY1
Fang, TH; Kao, CH; Lin, CW1
Gálvez-Rodríguez, A; Kumar, M; Mohapatra, S; Mukherji, S; Padhye, LP; Shea, P; Snow, D1
Doucette, WJ; Lombardero, LR; Pérez, DJ1

Reviews

1 review(s) available for gemfibrozil and carbamazepine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

32 other study(ies) available for gemfibrozil and carbamazepine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Identification and prediction of promiscuous aggregating inhibitors among known drugs.
    Journal of medicinal chemistry, 2003, Oct-09, Volume: 46, Issue:21

    Topics: Antifungal Agents; beta-Lactamase Inhibitors; Chemical Phenomena; Chemistry, Physical; Chymotrypsin; Enzyme Inhibitors; Kinetics; Light; Malate Dehydrogenase; Models, Molecular; Molecular Conformation; Scattering, Radiation; Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Removal of selected non-steroidal anti-inflammatory drugs (NSAIDs), gemfibrozil, carbamazepine, beta-blockers, trimethoprim and triclosan in conventional wastewater treatment plants in five EU countries and their discharge to the aquatic environment.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2004, Volume: 50, Issue:5

    Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Europe; Gemfibrozil; Humans; Pharmaceutical Preparations; Plants; Risk Assessment; Triclosan; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical

2004
Effects of selected pharmaceutical products on phagocytic activity in Elliptio complanata mussels.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2006, Volume: 143, Issue:2

    Topics: Animals; Bivalvia; Carbamazepine; Cell Adhesion; Esterases; Gemfibrozil; Hemocytes; Lipid Peroxidation; Novobiocin; Phagocytosis; Structure-Activity Relationship; Waste Disposal, Fluid; Water Pollutants, Chemical

2006
Cytotoxicity assessment of four pharmaceutical compounds on the zebra mussel (Dreissena polymorpha) haemocytes, gill and digestive gland primary cell cultures.
    Chemosphere, 2011, Volume: 84, Issue:1

    Topics: Animals; Atenolol; Carbamazepine; Cells, Cultured; Diclofenac; Digestive System; Dreissena; Gemfibrozil; Gills; Hemocytes; Prescription Drugs; Water Pollutants, Chemical

2011
Effects of selected pharmaceutically active compounds on treatment performance in sequencing batch reactors mimicking wastewater treatment plants operations.
    Water research, 2011, Volume: 45, Issue:11

    Topics: Bacteria; Biodiversity; Bioreactors; Carbamazepine; Drug-Related Side Effects and Adverse Reactions; Gemfibrozil; Ketoprofen; Microbial Consortia; Naproxen; Pharmaceutical Preparations; Waste Disposal, Fluid; Water Microbiology; Water Pollutants, Chemical

2011
Occurrence and suitability of sucralose as an indicator compound of wastewater loading to surface waters in urbanized regions.
    Water research, 2011, Volume: 45, Issue:13

    Topics: Caffeine; Carbamazepine; DEET; Gemfibrozil; Phosphines; Primidone; Sucrose; Sulfamethoxazole; Water Pollutants, Chemical

2011
Validation and use of in vivo solid phase micro-extraction (SPME) for the detection of emerging contaminants in fish.
    Chemosphere, 2011, Volume: 85, Issue:9

    Topics: Animals; Atrazine; Benzhydryl Compounds; Carbamazepine; Diclofenac; Environmental Monitoring; Fishes; Fluoxetine; Gemfibrozil; Ibuprofen; Naproxen; Phenols; Solid Phase Extraction; Solid Phase Microextraction; Waste Disposal, Fluid; Water Pollutants, Chemical

2011
Distribution and temporal evolution of pharmaceutically active compounds alongside sewage sludge treatment. Risk assessment of sludge application onto soils.
    Journal of environmental management, 2012, Jul-15, Volume: 102

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Carbamazepine; Clofibric Acid; Environmental Pollutants; Environmental Pollution; Estradiol; Gemfibrozil; Propranolol; Risk Assessment; Sewage; Soil; Spain; Time Factors

2012
Removal of trace organic chemical contaminants by a membrane bioreactor.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2012, Volume: 66, Issue:9

    Topics: Amitriptyline; Bioreactors; Carbamazepine; Diazepam; Diclofenac; Fluoxetine; Gemfibrozil; Omeprazole; Organic Chemicals; Pharmaceutical Preparations; Sulfamethoxazole; Trimethoprim; Waste Disposal, Fluid; Water Pollutants, Chemical

2012
Sorption and degradation of pharmaceuticals and personal care products (PPCPs) in soils.
    Environmental science and pollution research international, 2013, Volume: 20, Issue:6

    Topics: Absorption; Benzhydryl Compounds; Biodegradation, Environmental; Carbamazepine; Cosmetics; Environmental Monitoring; Gemfibrozil; Groundwater; Pharmaceutical Preparations; Phenols; Soil; Soil Pollutants; Triclosan; Water Pollutants, Chemical

2013
Occurrence and distribution of pharmaceutically active and endocrine disrupting compounds in Singapore's marine environment: influence of hydrodynamics and physical-chemical properties.
    Environmental pollution (Barking, Essex : 1987), 2013, Volume: 182

    Topics: Carbamazepine; Endocrine Disruptors; Environmental Monitoring; Gemfibrozil; Hydrodynamics; Ibuprofen; Pharmaceutical Preparations; Seawater; Singapore; Triclosan; Waste Disposal Facilities; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical

2013
Emerging organic contaminants in coastal waters: anthropogenic impact, environmental release and ecological risk.
    Marine pollution bulletin, 2014, Aug-30, Volume: 85, Issue:2

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Aquatic Organisms; Caffeine; Carbamazepine; Chromatography, Liquid; Environmental Monitoring; Gemfibrozil; Humans; Ketamine; N-Methyl-3,4-methylenedioxyamphetamine; Population Density; Pseudoephedrine; Risk; Rivers; Seawater; Solid Phase Extraction; Taiwan; Tandem Mass Spectrometry; Water Pollutants, Chemical

2014
Effects of chronic, parental pharmaceutical exposure on zebrafish (Danio rerio) offspring.
    Aquatic toxicology (Amsterdam, Netherlands), 2014, Volume: 151

    Topics: Animals; Carbamazepine; Clutch Size; Embryo, Nonmammalian; Female; Gemfibrozil; Male; Reproduction; Sexual Behavior, Animal; Spermatozoa; Water Pollutants, Chemical; Zebrafish

2014
Modeling uptake of selected pharmaceuticals and personal care products into food crops from biosolids-amended soil.
    Environmental science & technology, 2014, Oct-07, Volume: 48, Issue:19

    Topics: Agriculture; Carbamazepine; Carbanilides; Cimetidine; Cosmetics; Crops, Agricultural; Diphenhydramine; Fluoxetine; Gemfibrozil; Miconazole; Models, Theoretical; Pharmaceutical Preparations; Plant Roots; Plant Shoots; Sewage; Soil Pollutants; Triclosan

2014
Occurrence of selected pharmaceuticals in the principal sewage treatment plants in Rome (Italy) and in the receiving surface waters.
    Environmental science and pollution research international, 2015, Volume: 22, Issue:8

    Topics: Carbamazepine; Chromatography, Liquid; Diclofenac; Environmental Monitoring; Estrone; Gemfibrozil; Humans; Ibuprofen; Ketoprofen; Naproxen; Pharmaceutical Preparations; Risk Assessment; Rivers; Rome; Seasons; Solid Phase Extraction; Tandem Mass Spectrometry; Waste Disposal, Fluid; Water Pollutants, Chemical

2015
Transport behavior of the pharmaceutical compounds carbamazepine, sulfamethoxazole, gemfibrozil, ibuprofen, and naproxen, and the lifestyle drug caffeine, in saturated laboratory columns.
    The Science of the total environment, 2017, Jul-15, Volume: 590-591

    Topics: Caffeine; Carbamazepine; Filtration; Gemfibrozil; Ibuprofen; Naproxen; Ontario; Silicon Dioxide; Sulfamethoxazole; Water Pollutants, Chemical

2017
The effects of parental carbamazepine and gemfibrozil exposure on sexual differentiation in zebrafish (Danio rerio).
    Environmental toxicology and chemistry, 2018, Volume: 37, Issue:6

    Topics: Animals; Carbamazepine; Female; Gemfibrozil; Gonads; Male; Maternal Exposure; Paternal Exposure; Sex Differentiation; Sex Ratio; Water Pollutants, Chemical; Zebrafish

2018
Gemfibrozil and carbamazepine decrease steroid production in zebrafish testes (Danio rerio).
    Aquatic toxicology (Amsterdam, Netherlands), 2018, Volume: 198

    Topics: Animals; Carbamazepine; Cholesterol; Chorionic Gonadotropin; Gemfibrozil; Humans; Hydroxycholesterols; Male; Pregnenolone; Reproduction; Steroids; Testis; Testosterone; Water Pollutants, Chemical; Zebrafish

2018
Occurrence and distribution of pharmaceutical compounds in the Danshuei River Estuary and the Northern Taiwan Strait.
    Marine pollution bulletin, 2019, Volume: 146

    Topics: Aquatic Organisms; Carbamazepine; Environmental Monitoring; Erythromycin; Estuaries; Gemfibrozil; Pharmaceutical Preparations; Rivers; Seawater; Taiwan; Water Pollutants, Chemical

2019
Photodegradation of a mixture of five pharmaceuticals commonly found in wastewater: Experimental and computational analysis.
    Environmental research, 2023, 01-01, Volume: 216, Issue:Pt 3

    Topics: Acetaminophen; Carbamazepine; Carbon; Diclofenac; Gemfibrozil; Pharmaceutical Preparations; Photolysis; Sulfamethoxazole; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical

2023
Influence of exposure time, physicochemical properties, and plant transpiration on the uptake dynamics and translocation of pharmaceutical and personal care products in the aquatic macrophyte Typha latifolia.
    The Science of the total environment, 2023, Oct-20, Volume: 896

    Topics: Carbamazepine; Chromatography, Liquid; Cosmetics; Fluoxetine; Gemfibrozil; Pharmaceutical Preparations; Plant Transpiration; Tandem Mass Spectrometry; Triclosan; Typhaceae; Water Pollutants, Chemical

2023