gemfibrozil has been researched along with bezafibrate in 128 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (7.81) | 18.7374 |
1990's | 49 (38.28) | 18.2507 |
2000's | 51 (39.84) | 29.6817 |
2010's | 17 (13.28) | 24.3611 |
2020's | 1 (0.78) | 2.80 |
Authors | Studies |
---|---|
Abraham, DJ; Kennedy, PE; Mehanna, AS; Patwa, DC; Williams, FL | 1 |
Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T | 1 |
Abuo-Rahma, Gel-D; Aly, OM; Idrees, GA; Radwan, MF | 1 |
Chalmers, DK; Chuang, S; Horne, J; Porter, CJ; Scanlon, MJ; Velkov, T; Wielens, J | 1 |
Maillet, EL; Margolskee, RF; Mosinger, B | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Fujiwara, R; Koga, T; Nakajima, M; Yokoi, T | 1 |
Fent, K; Popovic, M; Smital, T; Zaja, R | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Kashihara, M; Mizuguchi, M; Yokoyama, T | 1 |
Adzet, T; Alegret, M; Laguna, JC; Merlos, M; Sánchez, RM | 1 |
Bergmann, S; Fücker, K; Gross, P; Hanefeld, M; Hora, C; Julius, U | 1 |
Adzet, T; Alegret, M; Laguna, JC; Merlos, M; Sánchez, R | 1 |
de la Iglesia, FA; Gray, RH; Lucas, JA; McGuire, EJ | 1 |
Alvarez, L; Aránega, A; Aránega, AE; Fernández, JE; González, FJ; Muros, MA; Prados, J; Vélez, C | 1 |
Alvarez, L; Aránega, A; Aránega, AE; Fernández, JE; González, FJ; Linares, A; Muros, MA; Vélez, C | 1 |
Schwandt, P | 1 |
Frishman, WH; Kahn, S; Zimetbaum, P | 1 |
Kłosiewicz-Latoszek, L; Szostak, WB | 1 |
Garcia, RC; Nakandakare, E; Oliveira, HC; Quintão, EC; Rocha, JC; Sperotto, G | 1 |
Shapiro, DR; Walker, JF | 1 |
Carlson, LA | 1 |
Arsenio, L; Rossi, A | 1 |
Acacia, E; Jones, C; Kremer, P; Marowski, C | 1 |
Krause, BR; Newton, RS | 1 |
Weisweiler, P | 1 |
Hunninghake, DB; Peters, JR | 1 |
Grundy, SM; Vega, GL | 1 |
Eacho, PI; Foxworthy, PS | 1 |
Hirst, DG; Schwartz, HC; Wood, PJ | 1 |
Maxwell, RE; Nawrocki, JW; Uhlendorf, PD | 1 |
Adzet, T; Alegret, M; Cerqueda, E; Ferrando, R; Laguna, JC; Merlos, M; Sánchez, RM; Vázquez, M | 1 |
Abate, N; Bertolotti, M; Carulli, N; Concari, M; Guicciardi, ME; Loria, P; Pinetti, A | 1 |
Alvarez, L; Aránega, A; Aránega, AE; Gonzalez, AR; Melguizo, C; Muros, MA; Vélez, C | 1 |
Schonfeld, G | 1 |
Dujovne, CA; Lozada, A | 1 |
Adzet, T; Alegret, M; Ferrando, R; Laguna, JC; Merlos, M; Vázquez, M | 1 |
Betteridge, L; Chan, P; Gallagher, K; Munro, E; Patel, M; Schachter, M; Sever, P; Wolfe, J | 1 |
Branchi, A; Fasoli, A; Gugliandolo, AG; Rovellini, A; Sommariva, D | 1 |
Adzet, T; Alegret, M; Laguna, JC; Merlos, M; Sánchez, RM; Vázquez, M; Viñals, M | 2 |
Shepherd, J | 1 |
Baigts, F; Bruckert, E; De Gennes, JL; Malbecq, W | 1 |
Accatino, L; Amigo, L; Andrade, L; Chianale, J; Gonzalez, S; Nervi, F; Pizarro, M; Rigotti, A; Vollrath, V; Wielandt, AM | 1 |
Adzet, T; Alegret, M; Laguna, JC; Merlos, M; Muñoz, S; Vázquez, M | 1 |
Adzet, T; Alegret, M; Laguna, JC; López, M; Merlos, M; Rodríguez, C; Vázquez, M | 1 |
Coulter, DM | 1 |
Baldassarre, D; Banfi, C; Mussoni, L; Sironi, L; Tremoli, E | 1 |
Auerbach, BJ; Barnett, BC; DeMattos, RB; Essenburg, AD; Haubenwallner, S; Krause, BR; Leff, T; Minton, LL; Newton, RS; Pape, ME | 1 |
Adzet, T; Laguna, JC; Merlos, M; Vázquez, M | 1 |
Aranega, A; Aranega, AE; Gonzalez, FJ; Melguizo, C; Prados, JC; Velez, MC | 1 |
Diemer, S; Eberlein-König, B; Przybilla, B | 1 |
Auerbach, BJ; Barnett, BC; Bisgaier, CL; Bousley, R; Essenburg, AD; Kieft, KA; Krause, BR; Newton, RS; Stanfield, R | 1 |
Amacher, DE; Beck, R; Kenny, CV; Schomaker, SJ | 1 |
Grover, S; Hamilton, VH; Lavoie, F; Perreault, S | 1 |
de Wit, EC; Huisman, H; Kaptein, A; Neele, DM; Princen, HM | 1 |
Arrol, S; Bhatnagar, D; Durrington, PN; Julier, K; Mackness, MI; Morgan, J; Prais, H; Wood, GN | 1 |
Sinzinger, H | 1 |
Charach, G; Grosskopf, I; Weintraub, MS | 1 |
Beggs, PW; Clark, DW; Coulter, DM; Williams, SM | 1 |
Bergemann, R; Brandt, A; Siegrist, W | 1 |
Avramopoulos, A; Kounis, N; Kouskoukis, K; Pispirigos, K; Simopoulos, K | 1 |
Wallace, KB; Zhou, S | 1 |
Eriksson, P; Hamsten, A; Nilsson, L; Takemura, T | 1 |
Bellamy, FD; Chaput, E; Edgar, AD; Maubrou-Sanchez, D | 1 |
Bottoni, P; Ficarra, S; Giardina, B; Nocca, G; Puggioni, P; Remiddi, F; Rumi, C; Scatena, R; Sole, PD | 1 |
Jones, PH | 1 |
Brinton, EA; Krakoff, J; Vela, BS | 1 |
Durrington, P | 1 |
Faergeman, O | 1 |
Oboubie, K; Ogunko, A | 1 |
Abramowicz, D; Antoine, M; Broeders, N; Knoop, C; Tielemans, C | 1 |
Black, DM | 1 |
Rubins, HB | 1 |
Barter, PJ; Dimmitt, SB; Watts, GF | 1 |
Backman, JT; Kivistö, KT; Kyrklund, C; Laitila, J; Neuvonen, M; Neuvonen, PJ | 1 |
Hamilton-Craig, I | 1 |
Mikhailidis, DP; Rizos, E | 2 |
Kamaliah, MD; Sanjay, LD | 1 |
Muscari, A; Puddu, GM; Puddu, P | 1 |
Athyros, V; Bairaktari, E; Elisaf, M; Ganotakis, E; Rizos, E; Seferiades, C; Tsimihodimos, V | 1 |
Bellido, A; Cabrero, A; Laguna, JC; Novell, F; Rodríguez, C; Roglans, N; Ros, E; Zambón, D | 1 |
Bortolini, M; Farnier, M; Freudenreich, MO; Gonasun, L; Isaacsohn, JL; Salko, T; Troendle, AJ | 1 |
Barberá, G; Chacón, P; Hernández, C; Lecube, A; Lima, J; Simó, R | 1 |
Fujisaki, K; Itoh, Y; Maiguma, T; Makino, K; Oishi, R; Sasaguri, T; Takahashi-Yanaga, F; Teshima, D | 1 |
Boden, WE | 1 |
Dejager, S; Farnier, M; Gonasun, L; Isaacsohn, JL; Salko, T; Troendle, AJ | 1 |
Alegret, M; Laguna, JC; Novell, F; Roglans, N; Ros, E; Sánchez, RM; Vázquez-Carrera, M; Zambón, D | 1 |
Agellon, LB; Gbaguidi, GF | 1 |
Dobordzhginidze, LM; Gratsianskiĭ, NA | 1 |
Baldwin, GS; Ford, J; Lachal, S; Shulkes, A | 1 |
Bottoni, P; De Sole, P; Ferrari, F; Giardina, B; Martorana, GE; Rossi, C; Scatena, R | 1 |
Ascaso, JF; Felipe Pallardo, L; Fernández-Cruz, A; González Santos, P; Hernández Mijares, A; Mangas Rojas, A; Millán, J; Pedro-Botet, J; Pérez-Jiménez, F; Pía, G; Pintó, X; Plaza, I; Rubiés-Prat, J | 1 |
Malcolm, J; Meggison, H; Sigal, R | 1 |
Brennan, SO; George, PM; Maghzal, GJ | 1 |
Bartos, J; Dolezel, J; Ehrmann, J; Kolar, Z; Malikova, J; Strakova, N | 1 |
Backman, JT; Kajosaari, LI; Laitila, J; Neuvonen, PJ | 1 |
Lee, LE; Liu, G; Metcalfe, CD; Moon, TW; Trudeau, VL | 1 |
Balice, M; Chironi, G; Del-Pino, M; Gariepy, J; Levenson, J; Simon, A | 1 |
Elisaf, MS; Mikhailidis, DP; Milionis, HJ | 1 |
Hauzer, A; Komsta, Ł; Majchrzak, E; Misztal, G | 1 |
Duriez, P; Fruchart, JC | 1 |
Patel, J | 1 |
Arnaout, A; Malcolm, J; Sigal, R | 1 |
Dellavalle, RP; Drake, AL; Freeman, SR; Graber, M; Heilig, LF; McNealy, K; Schilling, LM | 1 |
Isidori, M; Nardelli, A; Parrella, A; Pascarella, L; Rubino, M | 1 |
Berneis, K; Rizzo, M | 1 |
Betti, M; Canesi, L; Ciacci, C; Gallo, G; Lorusso, LC; Marcomini, A; Poiana, G; Regoli, F | 1 |
Gonzalez, FJ; Hossain, MA; Tsujita, M; Yokoyama, S | 1 |
Anzivino, C; Bertolotti, M; Carulli, L; Carulli, N; Corna, F; Del Puppo, M; Gabbi, C; Kienle, MG; Loria, P; Pellegrini, E; Ricchi, M; Zambianchi, L | 1 |
Akita, N; Fukutomi, T; Gonzalez, FJ; Hossain, MA; Kimura, G; Ogata, M; Staels, B; Suzuki, S; Tsujita, M; Yokoyama, S | 1 |
Abourbih, S; Eisenberg, MJ; Filion, KB; Genest, J; Joseph, L; Pilote, L; Poirier, P; Rinfret, S; Schiffrin, EL | 1 |
Elsby, R; Holmes, VE; Lambert, C; Sharma, P; Surry, D | 1 |
Bloomgarden, ZT; Drexler, A | 1 |
Boltes, K; García-Calvo, E; Rosal, R | 1 |
Oliveira, HC; Patrício, PR; Raposo, HF; Simões, MC | 1 |
Dijkstra, IM; Kemp, S; Ofman, R; Schackmann, MJ; Wanders, RJ | 1 |
Hao, Z; Liu, B; Liu, M; Tao, W; Wang, D | 1 |
Heo, TH; Hong, M; Jun, HS; Kim, SJ; Lee, HK; Lee, YS; Song, KD; Yi, S | 1 |
González, I; Loera, O; Ramírez-Saad, H; Rodríguez-Nava, O | 1 |
Briel, M; Ferreira-González, I; Jakob, T; Nordmann, AJ; Schandelmaier, S | 1 |
Fang, J; Guo, K; Hou, S; Hua, Z; Kong, X; Li, X; Ren, Z; Wu, Z | 1 |
Chen, YH; Hu, P; Peng, ML; Ren, H; Zhan, Z | 1 |
31 review(s) available for gemfibrozil and bezafibrate
Article | Year |
---|---|
Effects of gemfibrozil and other fibric acid derivatives on blood lipids and lipoproteins.
Topics: Bezafibrate; Cholesterol, HDL; Clofibric Acid; Diabetes Mellitus, Type 2; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Kidney Diseases; Lipoproteins, VLDL; Metabolic Clearance Rate; Triglycerides | 1991 |
Effect of fibric acid derivatives on blood lipid and lipoprotein levels.
Topics: Anticholesteremic Agents; Bezafibrate; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Lipids; Lipoproteins; Pentanoic Acids | 1987 |
Fibric acids: effects on lipids and lipoprotein metabolism.
Topics: Bezafibrate; Bile Acids and Salts; Cholesterol; Clofibrate; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Liver; Pentanoic Acids; Triglycerides | 1987 |
The effects of fibrates on lipoprotein and hemostatic coronary risk factors.
Topics: Arteriosclerosis; Bezafibrate; Blood Coagulation; Clofibric Acid; Coronary Disease; Fenofibrate; Fibric Acids; Gemfibrozil; Hemostasis; Humans; Hypolipidemic Agents; Lipoproteins; Risk Factors | 1994 |
Drug interactions with fibric acids.
Topics: Anticoagulants; Bezafibrate; Clofibrate; Clofibric Acid; Contraceptives, Oral; Coronary Disease; Drug Interactions; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Lipids | 1994 |
Mechanism of action of fibrates.
Topics: Apolipoproteins B; Bezafibrate; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Lipoproteins, LDL; Male; Receptors, LDL | 1993 |
A head-to-head comparison of the cost effectiveness of HMG-CoA reductase inhibitors and fibrates in different types of primary hyperlipidemia.
Topics: Bezafibrate; Coronary Disease; Cost-Benefit Analysis; Double-Blind Method; Female; Fenofibrate; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemia, Familial Combined; Hyperlipidemias; Hypolipidemic Agents; Male | 1997 |
[Antilipemic agents and atherothrombosis. Effects of antilipemic agents on blood platelet function, coagulation and fibrinolysis].
Topics: Anticholesteremic Agents; Antiporters; Arteriosclerosis; Bezafibrate; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Clinical Trials as Topic; Clofibric Acid; Fenofibrate; Fibrinolysis; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Niacin; Pravastatin; Risk Factors; Simvastatin; Thrombosis | 1998 |
Fibrates and high-dose statins to prevent coronary heart disease events.
Topics: Angioplasty, Balloon, Coronary; Bezafibrate; Coronary Disease; Female; Gemfibrozil; Humans; Hypolipidemic Agents; Male; Myocardial Revascularization; Randomized Controlled Trials as Topic; Triglycerides | 1999 |
The role of fibric acid derivatives in the secondary prevention of coronary heart disease.
Topics: Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Coronary Artery Disease; Coronary Disease; Gemfibrozil; Humans; Hypolipidemic Agents; Triglycerides | 2000 |
Hypertriglyceridemia and the fibrate trials.
Topics: Bezafibrate; Cardiovascular Diseases; Clinical Trials as Topic; Female; Gemfibrozil; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Lipoproteins; Lipoproteins, HDL; Male; Risk; Triglycerides | 2000 |
Statins in children: what do we know and what do we need to do?
Topics: Atorvastatin; Bezafibrate; Child; Child Welfare; Cost-Benefit Analysis; Drug Approval; Gemfibrozil; Heptanoic Acids; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lovastatin; Pyridines; Pyrroles; Simvastatin | 2001 |
Triglycerides and coronary heart disease: implications of recent clinical trials.
Topics: Aged; Bezafibrate; Controlled Clinical Trials as Topic; Coronary Artery Disease; Female; Gemfibrozil; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Male; Middle Aged; Prognosis; Treatment Outcome; Triglycerides | 2000 |
Normocholesterolaemic dyslipidaemia: is there a role for fibrates?
Topics: Bezafibrate; Clinical Trials as Topic; Coronary Disease; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents | 2001 |
Are high density lipoprotein (HDL) and triglyceride levels relevant in stroke prevention?
Topics: Adult; Bezafibrate; Biomarkers; Cholesterol; Coronary Disease; Female; Follow-Up Studies; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lipids; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Stroke; Triglycerides | 2001 |
Are high-density lipoprotein and triglyceride levels important in secondary prevention: impressions from the BIP and VA-HIT trials.
Topics: Bezafibrate; Clinical Trials as Topic; Coronary Disease; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Risk Factors; Triglycerides | 2002 |
Lipid-lowering drugs: are adverse effects predictable and reversible?
Topics: Aryl Hydrocarbon Hydroxylases; Bezafibrate; Cholesterol, LDL; Cytochrome P-450 Enzyme System; Digestive System; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Liver; Renal Insufficiency; Rhabdomyolysis; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases | 2002 |
Therapeutic implications of recent ATP III guidelines and the important role of combination therapy in total dyslipidemia management.
Topics: Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Diabetic Angiopathies; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Lovastatin; Metabolic Syndrome; Practice Guidelines as Topic | 2003 |
Role of fibrates in reducing coronary risk: a UK Consensus.
Topics: Bezafibrate; Cholesterol, HDL; Coronary Disease; Drug Therapy, Combination; Fenofibrate; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Metabolic Syndrome | 2004 |
[Fibrates: mechanism of action, effect on levels of lipids and lipoproteins, risk of coronary events. Part 1. Clofibrate, gemfibrosil, besafibrate].
Topics: Bezafibrate; Clofibrate; Female; Gemfibrozil; Humans; Hypertriglyceridemia; Hypolipidemic Agents; Lipoproteins; Male; Randomized Controlled Trials as Topic | 2004 |
Significance of high density lipoprotein-cholesterol in cardiovascular risk prevention: recommendations of the HDL Forum.
Topics: Bezafibrate; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Fenofibrate; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Niacin; Risk Assessment | 2004 |
Prevention of cardiovascular events in diabetes.
Topics: Angioplasty, Balloon; Antihypertensive Agents; Aspirin; Bezafibrate; Cardiovascular Diseases; Coronary Artery Bypass; Diabetic Angiopathies; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Platelet Glycoprotein GPIIb-IIIa Complex; Smoking Cessation | 2004 |
Treatment of dyslipidaemias in patients with established vascular disease: a revival of the fibrates.
Topics: Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Clofibric Acid; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Myocardial Ischemia; Randomized Controlled Trials as Topic; Triglycerides | 2000 |
Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism.
Topics: Animals; Anticholesteremic Agents; Atherosclerosis; Bezafibrate; Biological Transport; Cholesterol, HDL; Clofibric Acid; Coronary Artery Disease; Fenofibrate; Gemfibrozil; Humans; Hypercholesterolemia; Hypertriglyceridemia; Hypolipidemic Agents; Liver; PPAR alpha; Randomized Controlled Trials as Topic; Triglycerides | 2006 |
Dyslipidaemia in diabetes.
Topics: Azetidines; Bezafibrate; Diabetes Complications; Diabetic Angiopathies; Drug Therapy, Combination; Dyslipidemias; Ezetimibe; Fish Oils; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Niacin | 2006 |
Prevention of cardiovascular events in diabetes.
Topics: Angioplasty, Balloon; Antihypertensive Agents; Aspirin; Bezafibrate; Cardiovascular Diseases; Clopidogrel; Diabetic Angiopathies; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Smoking Cessation; Ticlopidine | 2006 |
Statins, fibrates, and melanoma risk: a systematic review and meta-analysis.
Topics: Atorvastatin; Bezafibrate; Clofibrate; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Incidence; Lovastatin; Melanoma; Odds Ratio; Pravastatin; Pyrroles; Randomized Controlled Trials as Topic; Reproducibility of Results; Simvastatin; Skin Neoplasms; United States | 2006 |
The clinical significance of the size of low-density-lipoproteins and the modulation of subclasses by fibrates.
Topics: Bezafibrate; Clofibric Acid; Dyslipidemias; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Lipoproteins, LDL; Particle Size; Treatment Outcome | 2007 |
Effect of fibrates on lipid profiles and cardiovascular outcomes: a systematic review.
Topics: Anticholesteremic Agents; Bezafibrate; Cardiovascular Diseases; Cholesterol, LDL; Clofibric Acid; Female; Fenofibrate; Gemfibrozil; Humans; Hyperlipidemias; Prognosis; Randomized Controlled Trials as Topic; Risk Assessment; Survival Analysis; Treatment Outcome | 2009 |
Fibrates for secondary prevention of cardiovascular disease and stroke.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Bezafibrate; Cardiovascular Diseases; Cause of Death; Cholesterol, HDL; Clofibrate; Coronary Disease; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypertriglyceridemia; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke | 2015 |
Fibrates for primary prevention of cardiovascular disease events.
Topics: Atorvastatin; Bezafibrate; Cardiovascular Diseases; Clofibric Acid; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Middle Aged; Myocardial Infarction; Primary Prevention; Simvastatin; Stroke | 2016 |
13 trial(s) available for gemfibrozil and bezafibrate
Article | Year |
---|---|
[Different effects of fibrates on the lipoprotein profile. Comparison of the effectiveness of gemfibrozil and bezafibrate in various types of hyperlipoproteinemia].
Topics: Adult; Aged; Bezafibrate; Cholesterol; Female; Gemfibrozil; Humans; Hyperlipoproteinemias; Lipoproteins; Male; Middle Aged; Triglycerides | 1992 |
Effects of simvastatin, bezafibrate and gemfibrozil on the quantity and composition of plasma lipoproteins.
Topics: Adult; Aged; Apolipoproteins; Bezafibrate; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl CoA Reductases; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin | 1990 |
Hydroxymethylglutaryl coenzyme A reductase inhibitors as monotherapy in the treatment of hypercholesterolemia.
Topics: Bezafibrate; Cholestyramine Resin; Double-Blind Method; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Lipids; Lovastatin; Probucol; Randomized Controlled Trials as Topic; Simvastatin | 1990 |
Therapeutic effects of bezafibrate and gemfibrozil in hyperlipoproteinaemia type IIa and IIb.
Topics: Adult; Aged; Argentina; Arteriosclerosis; Bezafibrate; Blood Glucose; Cholesterol; Cholesterol, HDL; Female; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Male; Middle Aged; Triglycerides | 1989 |
Effects of bezafibrate and gemfibrozil on serum lipoproteins in primary hypercholesterolemia.
Topics: Adult; Aged; Bezafibrate; Cholesterol, LDL; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged | 1988 |
Comparison of the efficacy of simvastatin and standard fibrate therapy in the treatment of primary hypercholesterolemia and combined hyperlipidemia.
Topics: Anticholesteremic Agents; Bezafibrate; Cholesterol, LDL; Clofibric Acid; Fatty Acids, Volatile; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Lipoproteins; Lovastatin; Male; Middle Aged; Simvastatin; Triglycerides | 1995 |
A head-to-head comparison of the cost effectiveness of HMG-CoA reductase inhibitors and fibrates in different types of primary hyperlipidemia.
Topics: Bezafibrate; Coronary Disease; Cost-Benefit Analysis; Double-Blind Method; Female; Fenofibrate; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemia, Familial Combined; Hyperlipidemias; Hypolipidemic Agents; Male | 1997 |
Effects of two different fibric acid derivatives on lipoproteins, cholesteryl ester transfer, fibrinogen, plasminogen activator inhibitor and paraoxonase activity in type IIb hyperlipoproteinaemia.
Topics: Adult; Aged; Aryldialkylphosphatase; Bezafibrate; Carrier Proteins; Cholesterol Ester Transfer Proteins; Cross-Over Studies; Double-Blind Method; Esterases; Female; Fibrinogen; Gemfibrozil; Glycoproteins; Humans; Hyperlipoproteinemia Type II; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged; Plasminogen Activators | 1998 |
Effects of fibric acid derivatives and metformin on postprandial lipemia.
Topics: Bezafibrate; Chylomicrons; Gemfibrozil; Glucose Tolerance Test; Humans; Hypertriglyceridemia; Hypoglycemic Agents; Hypolipidemic Agents; Lipoproteins, HDL; Male; Metformin; Middle Aged; Postprandial Period | 1998 |
Plasma concentrations of active lovastatin acid are markedly increased by gemfibrozil but not by bezafibrate.
Topics: Adult; Area Under Curve; Bezafibrate; Cross-Over Studies; Drug Interactions; Female; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Lovastatin; Male | 2001 |
Fibrate treatment does not modify the expression of acyl coenzyme A oxidase in human liver.
Topics: Acyl-CoA Oxidase; Apolipoprotein A-I; Apolipoproteins B; Bezafibrate; Carnitine O-Palmitoyltransferase; Cholecystectomy; Cholelithiasis; Cholesterol, HDL; Cholesterol, LDL; DNA Primers; Female; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Liver; Male; Middle Aged; Oxidoreductases; Polymerase Chain Reaction; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Stearoyl-CoA Desaturase; Transcription Factors; Triglycerides | 2002 |
Effects of hypolipidemic treatment on serum markers of vascular inflammation in dyslipidemic men.
Topics: Adult; Bezafibrate; Biomarkers; Chemokine CCL2; E-Selectin; Gemfibrozil; Humans; Hyperlipidemias; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Hypolipidemic Agents; Inflammation Mediators; Lovastatin; Male; Middle Aged; Simvastatin; Vascular Cell Adhesion Molecule-1 | 2003 |
Fibrates modify the expression of key factors involved in bile-acid synthesis and biliary-lipid secretion in gallstone patients.
Topics: Bezafibrate; Bile Acids and Salts; Cholesterol 7-alpha-Hydroxylase; Cholesterol, LDL; Down-Regulation; Female; Fenofibrate; Gallstones; Gemfibrozil; Humans; Hypolipidemic Agents; Lipid Metabolism; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction | 2004 |
85 other study(ies) available for gemfibrozil and bezafibrate
Article | Year |
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Design, synthesis, and testing of potential antisickling agents. 4. Structure-activity relationships of benzyloxy and phenoxy acids.
Topics: Acetates; Animals; Antisickling Agents; Benzyl Compounds; Binding Sites; Glycolates; Humans; Mice; Models, Molecular; Oxygen; Phenoxyacetates; Structure-Activity Relationship; X-Ray Diffraction | 1984 |
Characterization of the drug binding specificity of rat liver fatty acid binding protein.
Topics: Anilino Naphthalenesulfonates; Animals; Fatty Acid-Binding Proteins; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Fluorescence; Substrate Specificity | 2008 |
Design, synthesis and hypolipidemic activity of novel 2-(m-tolyloxy) isobutyric acid derivatives.
Topics: Animals; Cholesterol; Cholesterol, Dietary; Disease Models, Animal; Drug Design; Gemfibrozil; Hypolipidemic Agents; Male; Molecular Structure; Propionates; Rats; Rats, Wistar; Stereoisomerism; Triglycerides | 2009 |
Probing the fibrate binding specificity of rat liver fatty acid binding protein.
Topics: Animals; Binding Sites; Carboxylic Acids; Clofibric Acid; Esters; Fatty Acid-Binding Proteins; Fenofibrate; Hypolipidemic Agents; Ligands; Liver; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Rats; Spectrometry, Fluorescence; Substrate Specificity; Temperature; Thermodynamics | 2009 |
Phenoxy herbicides and fibrates potently inhibit the human chemosensory receptor subunit T1R3.
Topics: 2,4-Dichlorophenoxyacetic Acid; Animals; Benzene Derivatives; Bezafibrate; Cell Line; Cercopithecidae; Clofibric Acid; Gemfibrozil; Herbicides; Humans; Hypolipidemic Agents; Indoleacetic Acids; Mice; Protein Subunits; Receptors, G-Protein-Coupled; Recombinant Fusion Proteins; Structure-Activity Relationship | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Camphanes; Comet Assay; DNA Damage; Glucuronides; Glucuronosyltransferase; HEK293 Cells; Hepatocytes; Humans; Kidney | 2011 |
Molecular characterization of zebrafish Oatp1d1 (Slco1d1), a novel organic anion-transporting polypeptide.
Topics: Animals; Evolution, Molecular; Glycosylation; Gonadal Steroid Hormones; HEK293 Cells; Humans; Ion Transport; Organic Anion Transporters; Protein Multimerization; Zebrafish; Zebrafish Proteins | 2013 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Repositioning of the Anthelmintic Drugs Bithionol and Triclabendazole as Transthyretin Amyloidogenesis Inhibitors.
Topics: Amyloid Neuropathies, Familial; Anthelmintics; Bithionol; Crystallography, X-Ray; Drug Repositioning; Humans; Prealbumin; Thermodynamics; Triclabendazole | 2021 |
Differential inhibition of long-chain acyl-CoA hydrolases by hypolipidemic drugs in vitro.
Topics: Animals; Bezafibrate; Clofibric Acid; Gemfibrozil; Hypolipidemic Agents; Liver; Male; Palmitoyl Coenzyme A; Palmitoyl-CoA Hydrolase; Rats; Rats, Inbred Strains; Subcellular Fractions | 1992 |
In vitro effect of clofibric acid derivatives on rat hepatic microsomal electron transport chains.
Topics: Animals; Bezafibrate; Clofibric Acid; Cytochromes b5; Electron Transport; Gemfibrozil; Kinetics; Male; Microsomes, Liver; NADH Dehydrogenase; NADPH Dehydrogenase; Rats; Rats, Inbred Strains | 1991 |
Peroxisome induction potential and lipid-regulating activity in rats. Quantitative microscopy and chemical structure-activity relationships.
Topics: Amides; Animals; Bezafibrate; Gemfibrozil; Lipids; Lipoproteins; Liver; Microbodies; Organ Size; Propionates; Rats; Structure-Activity Relationship | 1991 |
Effects of fibric acid derivatives on accumulation of actin in myocardiocytes.
Topics: Actins; Animals; Bezafibrate; Cells, Cultured; Chick Embryo; Cytoskeleton; Electrophoresis, Polyacrylamide Gel; Fenofibrate; Gemfibrozil; Heart; Immunoblotting; Myocardium | 1991 |
Influence of fibric acid derivatives on intermediate filament proteins in myocardiocyte cultures.
Topics: Animals; Bezafibrate; Cells, Cultured; Chick Embryo; Cytoskeletal Proteins; Desmin; Fenofibrate; Gemfibrozil; Heart; In Vitro Techniques; Intermediate Filament Proteins; Myocardium; Vimentin | 1991 |
Fibrates and triglyceride metabolism.
Topics: Bezafibrate; Clofibrate; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Triglycerides | 1991 |
Comparative studies on the influence of different fibrates on serum lipoproteins in endogenous hyperlipoproteinaemia.
Topics: Adult; Aged; Bezafibrate; Cholesterol; Clofibrate; Clofibric Acid; Colestipol; Female; Fenofibrate; Gemfibrozil; Humans; Hyperlipoproteinemias; Hypolipidemic Agents; Lipoproteins; Male; Middle Aged; Probucol | 1991 |
[A case of familial hypercholesterolemia with therapeutic difficulties].
Topics: Adult; Bezafibrate; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Lovastatin; Male; Nicotinic Acids; Simvastatin | 1990 |
[Efficacy of blood lipid normalization and tolerance in dyslipidemic patients treated for 18 months with fibric acid derivatives].
Topics: Adult; Bezafibrate; Drug Evaluation; Female; Fenofibrate; Gemfibrozil; Humans; Hyperlipidemias; Lipids; Male; Middle Aged; Propionates; Time Factors | 1989 |
Gemfibrozil increases both apo A-I and apo E concentrations. Comparison to other lipid regulators in cholesterol-fed rats.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins A; Apolipoproteins E; Bezafibrate; Cholesterol, Dietary; Cholesterol, HDL; Clofibrate; Clofibric Acid; Fenofibrate; Fibric Acids; Gemfibrozil; Male; Pentanoic Acids; Rats; Rats, Inbred Strains; Valerates | 1986 |
Conditions influencing the induction of peroxisomal beta-oxidation in cultured rat hepatocytes.
Topics: Animals; Bezafibrate; Catalase; Cell Survival; Clofibric Acid; Fibric Acids; Gemfibrozil; In Vitro Techniques; Liver; Male; Microbodies; Pentanoic Acids; Rats; Rats, Inbred F344 | 1986 |
The modification of hemoglobin affinity for oxygen and tumor radiosensitivity by antilipidemic drugs.
Topics: Animals; Bezafibrate; Clofibrate; Combined Modality Therapy; Gemfibrozil; Hemoglobins; Hypolipidemic Agents; Mice; Neoplasm Transplantation; Oxygen; Pentanoic Acids; Radiation-Sensitizing Agents; Sarcoma, Experimental | 1987 |
Some comparative effects of gemfibrozil, clofibrate, bezafibrate, cholestyramine and compactin on sterol metabolism in rats.
Topics: Animals; Anticholesteremic Agents; Bezafibrate; Caprylates; Carbon Radioisotopes; Cholesterol; Cholesterol, Dietary; Cholestyramine Resin; Clofibrate; Gemfibrozil; Hypolipidemic Agents; Liver; Lovastatin; Male; Mevalonic Acid; Naphthalenes; Pentanoic Acids; Rats; Rats, Inbred F344; Sterols; Valerates | 1983 |
Selective modification of rat hepatic microsomal fatty acid chain elongation and desaturation by fibrates: relationship with peroxisome proliferation.
Topics: Acetyltransferases; Animals; Bezafibrate; Clofibrate; Dietary Fats; Fatty Acid Desaturases; Fatty Acid Elongases; Fatty Acids; Gemfibrozil; Male; Microbodies; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Effects of different phenotypes of hyperlipoproteinemia and of treatment with fibric acid derivatives on the rates of cholesterol 7 alpha-hydroxylation in humans.
Topics: Adult; Bezafibrate; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Female; Gemfibrozil; Humans; Hyperlipidemia, Familial Combined; Hyperlipoproteinemia Type II; Male; Middle Aged | 1995 |
Changes in subcellular accumulation of contractile proteins in myocardiocyte cultures: effects of fibric acid derivatives.
Topics: Actinin; Animals; Bezafibrate; Cells, Cultured; Chick Embryo; Contractile Proteins; Electrophoresis, Polyacrylamide Gel; Fenofibrate; Gemfibrozil; Heart; Immunoblotting; Myocardial Contraction; Myocardium; Tropomyosin; Troponin; Troponin T | 1993 |
Relationship between plasma lipids and palmitoyl-CoA hydrolase and synthetase activities with peroxisomal proliferation in rats treated with fibrates.
Topics: Animals; Bezafibrate; Cholesterol; Clofibrate; Coenzyme A Ligases; Diet; Gemfibrozil; Hypolipidemic Agents; Lipids; Liver; Male; Microbodies; Organ Size; Palmitoyl-CoA Hydrolase; Rats; Rats, Sprague-Dawley; Repressor Proteins; Saccharomyces cerevisiae Proteins; Triglycerides | 1994 |
Growth inhibition of human vascular smooth muscle cells by fenofibrate: a possible therapy for restenosis.
Topics: Bezafibrate; Cell Division; Cells, Cultured; Clofibrate; Fenofibrate; Gemfibrozil; Graft Occlusion, Vascular; Humans; Muscle, Smooth; Platelet-Derived Growth Factor; Saphenous Vein | 1994 |
Effect of three fibrate derivatives and of two HMG-CoA reductase inhibitors on plasma fibrinogen level in patients with primary hypercholesterolemia.
Topics: Adult; Aged; Bezafibrate; Cholesterol, Dietary; Combined Modality Therapy; Female; Fenofibrate; Fibrinogen; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipoproteinemia Type II; Lipids; Lovastatin; Male; Middle Aged; Pravastatin; Simvastatin | 1993 |
Fibrates modify rat hepatic fatty acid chain elongation and desaturation in vitro.
Topics: Acetyltransferases; Animals; Bezafibrate; Clofibric Acid; Cytosol; Fatty Acid Desaturases; Fatty Acid Elongases; Gemfibrozil; Liver; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 1993 |
Cytosolic lipogenic enzymes: effect of fibric acid derivatives in vitro.
Topics: Animals; Bezafibrate; Clofibric Acid; Cytosol; Enzyme Inhibitors; Fatty Acids; Gemfibrozil; Kinetics; Male; Microsomes, Liver; Rats; Rats, Sprague-Dawley | 1993 |
Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Bezafibrate; Bile; Bile Canaliculi; Clofibrate; Clofibric Acid; DNA Primers; Drug Resistance, Multiple; Fenofibrate; Fibric Acids; Gemfibrozil; Gene Expression; Hypolipidemic Agents; Liver; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Multigene Family; Phospholipids; RNA, Messenger; RNA, Ribosomal, 18S | 1996 |
Differential effects of fibrates on the acyl composition of microsomal phospholipids in rats.
Topics: Animals; Bezafibrate; Cell Division; Clofibrate; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Gemfibrozil; Hypolipidemic Agents; Lipids; Liver; Male; Microbodies; Phosphatidylcholines; Phosphatidylethanolamines; Rats; Rats, Sprague-Dawley; Time Factors | 1995 |
Different effects of fibrates on the microsomal fatty acid chain elongation and the acyl composition of phospholipids in guinea-pigs.
Topics: Animals; Bezafibrate; Clofibrate; Fatty Acid Synthases; Fatty Acids; Gemfibrozil; Guinea Pigs; Hypolipidemic Agents; Male; Microsomes, Liver; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Palmitoyl-CoA Hydrolase; Phospholipids | 1995 |
Reasons for stopping drugs are monitored in New Zealand.
Topics: Adverse Drug Reaction Reporting Systems; Bezafibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Lovastatin; New Zealand; Product Surveillance, Postmarketing; Simvastatin | 1996 |
Plasminogen activator inhibitor type 1 secretion by HepG2 cells: opposite effects of two fibric acid derivatives.
Topics: Bezafibrate; Cell Line; Gemfibrozil; Humans; Plasminogen Activator Inhibitor 1 | 1996 |
Hypolipidemic activity of select fibrates correlates to changes in hepatic apolipoprotein C-III expression: a potential physiologic basis for their mode of action.
Topics: Animals; Apolipoprotein C-III; Apolipoproteins C; Bezafibrate; Cholesterol; Clofibrate; Fenofibrate; Gemfibrozil; Hypolipidemic Agents; Liver; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Triglycerides | 1995 |
Decreased susceptibility to copper-induced oxidation of rat-lipoproteins after fibrate treatment: influence of fatty acid composition.
Topics: Animals; Antioxidants; Bezafibrate; Clofibrate; Copper Sulfate; Fatty Acids; Gemfibrozil; Hypolipidemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Rats; Rats, Sprague-Dawley | 1996 |
Modulation of cardiac intermediate filament proteins in the chick heart by fibric acid derivatives.
Topics: Animals; Bezafibrate; Cells, Cultured; Chick Embryo; Cytoskeleton; Densitometry; Electrophoresis, Polyacrylamide Gel; Fenofibrate; Gemfibrozil; Heart; Intermediate Filament Proteins; Myocardium | 1995 |
Evaluation of the phototoxic properties of some hypolipidemics in vitro: fenofibrate exhibits a prominent phototoxic potential in the UVA and UVB region.
Topics: Bezafibrate; Clofibrate; Dermatitis, Phototoxic; Drug Evaluation, Preclinical; Fenofibrate; Gemfibrozil; Hemolysis; Humans; Hypolipidemic Agents; In Vitro Techniques; Ultraviolet Rays | 1996 |
Opposite effects of bezafibrate and gemfibrozil in both normal and hypertriglyceridemic rats.
Topics: Animals; Apolipoproteins B; Apolipoproteins E; Bezafibrate; Body Weight; Cholesterol; Cholesterol, LDL; Dose-Response Relationship, Drug; Gemfibrozil; Hypertriglyceridemia; Hypolipidemic Agents; Immunoelectrophoresis; Lipoprotein Lipase; Liver; Male; Rats; Rats, Sprague-Dawley; Spectrophotometry; Triglycerides | 1996 |
Hepatic microsomal enzyme induction, beta-oxidation, and cell proliferation following administration of clofibrate, gemfibrozil, or bezafibrate in the CD rat.
Topics: Animals; Anticholesteremic Agents; Bezafibrate; Clofibrate; Cyclin-Dependent Kinases; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Enzyme Induction; Female; Gemfibrozil; Isoenzymes; Liver; Male; Microbodies; Microsomes, Liver; Mixed Function Oxygenases; Organ Size; Oxidation-Reduction; Palmitoyl Coenzyme A; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred Strains; Sex Characteristics | 1997 |
No effect of fibrates on synthesis of apolipoprotein(a) in primary cultures of cynomolgus monkey and human hepatocytes: apolipoprotein A-I synthesis increased.
Topics: Animals; Apolipoprotein A-I; Apolipoproteins A; Bezafibrate; Cells, Cultured; Clofibrate; Clofibric Acid; Gemfibrozil; Humans; Liver; Macaca fascicularis | 1998 |
A comparison of the use, effectiveness and safety of bezafibrate, gemfibrozil and simvastatin in normal clinical practice using the New Zealand Intensive Medicines Monitoring Programme (IMMP).
Topics: Bezafibrate; Cohort Studies; Comorbidity; Diabetes Complications; Female; Gemfibrozil; Humans; Hypertension; Lipids; Male; Myocardial Ischemia; New Zealand; Practice Patterns, Physicians'; Product Surveillance, Postmarketing; Random Allocation; Retrospective Studies; Risk Factors; Simvastatin; Surveys and Questionnaires; Treatment Outcome | 1999 |
Cost-effectiveness study of a lipid-lowering therapy in hyperlipoproteinaemia type IIb and type IV (Frederickson).
Topics: Bezafibrate; Cost-Benefit Analysis; Diabetes Complications; Fenofibrate; Gemfibrozil; Humans; Hyperlipoproteinemia Type II; Hyperlipoproteinemia Type IV; Models, Econometric; Pyrazines; Treatment Outcome | 1993 |
Evaluation of kidney and liver subacute toxicity induced by Bezalip-Pravastatin-Lopid antihyperlipidaemic compounds in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antihypertensive Agents; Aspartate Aminotransferases; Bezafibrate; Enzyme Inhibitors; gamma-Glutamyltransferase; Gemfibrozil; Hydroxymethylglutaryl CoA Reductases; Kidney; Liver; Male; Pravastatin; Rats; Rats, Wistar | 1999 |
The effect of peroxisome proliferators on mitochondrial bioenergetics.
Topics: Animals; Bezafibrate; Calcium; Clofibrate; Clofibric Acid; Diethylhexyl Phthalate; Energy Metabolism; Fenofibrate; Fibric Acids; Gemfibrozil; Intracellular Membranes; Male; Membrane Potentials; Mitochondria, Liver; Mitochondrial Swelling; Oxygen; Permeability; Peroxisome Proliferators; Pyrimidines; Rats; Rats, Sprague-Dawley; Trichloroethylene | 1999 |
Effects of fibrate compounds on expression of plasminogen activator inhibitor-1 by cultured endothelial cells.
Topics: Bezafibrate; Cells, Cultured; Clofibric Acid; Endothelium, Vascular; Fenofibrate; Gemfibrozil; Humans; Hypolipidemic Agents; Plasminogen Activator Inhibitor 1; Pyrimidines; RNA, Messenger; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription, Genetic | 1999 |
Fenofibrate protects lipoproteins from lipid peroxidation: synergistic interaction with alpha-tocopherol.
Topics: Animals; Bezafibrate; Drug Synergism; Fenofibrate; Gemfibrozil; Hypolipidemic Agents; Lipid Peroxidation; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Rats; Rats, Sprague-Dawley; Vitamin E | 1999 |
Bezafibrate as differentiating factor of human myeloid leukemia cells.
Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Bezafibrate; Biomarkers; Cell Cycle; Cell Differentiation; Clofibric Acid; Gemfibrozil; Growth Inhibitors; HL-60 Cells; Humans; Integrin alphaXbeta2; K562 Cells; Leukemia, Myeloid; Lipopolysaccharide Receptors; U937 Cells | 1999 |
A case for lipid-lowering?
Topics: Bezafibrate; Cardiovascular Diseases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Coronary Disease; Diabetes Mellitus, Type 2; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Middle Aged; Pravastatin; Risk Factors; Triglycerides | 2000 |
Therapy and clinical trials.
Topics: Bezafibrate; Cholesterol, LDL; Clinical Trials as Topic; Coronary Disease; Diabetes Mellitus, Type 2; Gemfibrozil; Humans; Hypolipidemic Agents | 2000 |
Fibrate-induced increase in blood urea and creatinine: is gemfibrozil the only innocuous agent?
Topics: Bezafibrate; Clofibric Acid; Creatinine; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Kidney Diseases; Kidney Transplantation; Postoperative Period; Retrospective Studies; Urea | 2000 |
Normocholesterolaemic dysslipidaemia: is there a role for fibrates?
Topics: Bezafibrate; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Combination; Gemfibrozil; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Pyridines; Treatment Outcome; Triglycerides | 2001 |
Cholesterol-lowering drugs. Some drugs with demonstrated efficacy but different benefits in primary and secondary prevention.
Topics: Anticholesteremic Agents; Bezafibrate; Cholestyramine Resin; Clinical Trials as Topic; Clofibrate; Female; Gemfibrozil; Humans; Hypercholesterolemia; Lovastatin; Male; Myocardial Infarction; Pravastatin; Treatment Outcome | 1999 |
Rhabdomyolysis and acute renal failure following a switchover of therapy between two fibric acid derivatives.
Topics: Acute Kidney Injury; Aged; Bezafibrate; Coronary Disease; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Kidney Diseases; Male; Rhabdomyolysis | 2001 |
Effects of various fibrates on serum alkaline phosphatase activity.
Topics: Alkaline Phosphatase; Bezafibrate; Clofibric Acid; Female; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Male; Retrospective Studies; Treatment Outcome | 2002 |
Frequency of creatine kinase elevation during treatment with fluvastatin in combination with fibrates (bezafibrate, fenofibrate, or gemfibrozil).
Topics: Adult; Bezafibrate; Creatine Kinase; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Indoles; Male; Middle Aged | 2003 |
Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells.
Topics: Bezafibrate; Clofibrate; Clofibric Acid; Disease Models, Animal; Drug Synergism; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents; Receptors, Cytoplasmic and Nuclear; Reverse Transcriptase Polymerase Chain Reaction; Rhabdomyosarcoma, Embryonal; RNA, Messenger; Simvastatin; Time Factors; Transcription Factors; Tumor Cells, Cultured | 2003 |
Effects of baseline level of triglycerides on changes in lipid levels from combined fluvastatin + fibrate (bezafibrate, fenofibrate, or gemfibrozil).
Topics: Age Factors; Bezafibrate; Drug Combinations; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fluvastatin; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; Indoles; Lipid Metabolism; Lipoproteins; Male; Middle Aged; Retrospective Studies; Sex Factors; Treatment Outcome; Triglycerides | 2003 |
The inhibition of the human cholesterol 7alpha-hydroxylase gene (CYP7A1) promoter by fibrates in cultured cells is mediated via the liver x receptor alpha and peroxisome proliferator-activated receptor alpha heterodimer.
Topics: Acids, Acyclic; Animals; Bezafibrate; Binding Sites; Cell Line, Tumor; Cells, Cultured; Cholesterol 7-alpha-Hydroxylase; Clofibrate; Dimerization; DNA-Binding Proteins; Gemfibrozil; Gene Expression Regulation; Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 1-alpha; Hepatocyte Nuclear Factor 1-beta; Humans; Hydroxycholesterols; Ligands; Liver X Receptors; Nuclear Proteins; Orphan Nuclear Receptors; Promoter Regions, Genetic; Pyrimidines; Rats; Receptors, Cytoplasmic and Nuclear; Repetitive Sequences, Nucleic Acid; Response Elements; Transcription Factors | 2004 |
PPARalpha agonists stimulate progastrin production in human colorectal carcinoma cells.
Topics: Bezafibrate; Cell Proliferation; Clofibrate; Clofibric Acid; Colorectal Neoplasms; Fenofibrate; Fibric Acids; Gastrins; Gemfibrozil; Humans; Hypolipidemic Agents; Ligands; Peroxisome Proliferator-Activated Receptors; Protein Precursors; Pyrimidines; Radioimmunoassay; RNA, Messenger; Rosiglitazone; Thiazolidinediones; Vasodilator Agents | 2004 |
Mitochondrial respiratory chain dysfunction, a non-receptor-mediated effect of synthetic PPAR-ligands: biochemical and pharmacological implications.
Topics: Bezafibrate; Cell Differentiation; Cell Division; Clofibric Acid; Dose-Response Relationship, Drug; Electron Transport; Gemfibrozil; HL-60 Cells; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Ligands; Mitochondria; Receptors, Cytoplasmic and Nuclear; Thiazolidinediones; Transcription Factors | 2004 |
The sialic acid content of fibrinogen decreases during pregnancy and increases in response to fibrate therapy.
Topics: Bezafibrate; Case-Control Studies; Female; Fibrinogen; Gemfibrozil; Humans; Hyperlipidemias; Hypolipidemic Agents; N-Acetylneuraminic Acid; Pregnancy; Protein Subunits; Spectrometry, Mass, Electrospray Ionization; Thrombin Time | 2005 |
Peroxisome proliferator-activated receptors (PPAR) agonists affect cell viability, apoptosis and expression of cell cycle related proteins in cell lines of glial brain tumors.
Topics: Apoptosis; Bezafibrate; Brain Neoplasms; Cell Cycle; Cell Differentiation; Cell Survival; Flow Cytometry; Gemfibrozil; Glioblastoma; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Ligands; PPAR alpha; PPAR gamma; Thiazolidinediones; Tumor Cells, Cultured | 2005 |
Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin.
Topics: Aryl Hydrocarbon Hydroxylases; Bezafibrate; Carbamates; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fenofibrate; Gemfibrozil; Humans; Hypoglycemic Agents; In Vitro Techniques; Itraconazole; Microsomes, Liver; Midazolam; Paclitaxel; Piperidines; Quercetin; Rifampin | 2005 |
A teleost in vitro reporter gene assay to screen for agonists of the peroxisome proliferator-activated receptors.
Topics: Acetyl-CoA C-Acyltransferase; Alitretinoin; Angiogenesis Inhibitors; Animals; Bezafibrate; Cloning, Molecular; DNA; DNA, Complementary; Dose-Response Relationship, Drug; Environmental Monitoring; Gemfibrozil; Genes, Reporter; Humans; Hypolipidemic Agents; In Vitro Techniques; Liver; Luciferases; Oncorhynchus mykiss; Peroxisome Proliferator-Activated Receptors; Peroxisome Proliferators; Plasmids; PPAR alpha; PPAR-beta; Promoter Regions, Genetic; Pyrimidines; Rats; Retinoid X Receptors; Transcription, Genetic; Transfection; Tretinoin; Water Pollutants, Chemical | 2005 |
Differential associations of statin and fibrate treatment with carotid arterial remodeling.
Topics: Adult; Atorvastatin; Bezafibrate; Body Mass Index; Carotid Arteries; Cholesterol, HDL; Clofibric Acid; Cohort Studies; Dyslipidemias; Fatty Acids, Monounsaturated; Female; Fenofibrate; Fibric Acids; Fluvastatin; Gemfibrozil; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; Indoles; Male; Middle Aged; Multivariate Analysis; Pravastatin; Pyridines; Pyrroles; Risk Factors; Simvastatin; Treatment Outcome; Tunica Intima; Tunica Media; Ultrasonography | 2005 |
Separation of fibrate-type antihyperlipidemic drugs by capillary electrophoresis and their quantitation in pharmaceuticals.
Topics: Bezafibrate; Buffers; Clofibric Acid; Electrophoresis, Capillary; Fibric Acids; Gemfibrozil; Hydrogen-Ion Concentration; Hypolipidemic Agents; Pharmaceutical Preparations; Reproducibility of Results; Temperature; Time Factors | 2006 |
Toxic and genotoxic impact of fibrates and their photoproducts on non-target organisms.
Topics: Aliivibrio fischeri; Animals; Bezafibrate; Chlorophyta; Crustacea; Escherichia coli; Fenofibrate; Gemfibrozil; Hypolipidemic Agents; Lethal Dose 50; Mutagenicity Tests; No-Observed-Adverse-Effect Level; Rotifera; Salmonella typhimurium; Toxicity Tests, Acute; Toxicity Tests, Chronic; Ultraviolet Rays; Water Pollutants, Chemical | 2007 |
Effects of blood lipid lowering pharmaceuticals (bezafibrate and gemfibrozil) on immune and digestive gland functions of the bivalve mollusc, Mytilus galloprovincialis.
Topics: Animals; Bezafibrate; Cell Membrane; Digestive System; Dose-Response Relationship, Drug; Gemfibrozil; Hemocytes; Hypolipidemic Agents; Lipids; Mytilus; Phagocytosis; Water Pollutants, Chemical | 2007 |
Effects of fibrate drugs on expression of ABCA1 and HDL biogenesis in hepatocytes.
Topics: Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Bezafibrate; Blotting, Western; Cells, Cultured; Fenofibrate; Gemfibrozil; Gene Expression Regulation; Hepatocytes; Hypolipidemic Agents; Lipoproteins, HDL; Mice; Mice, Inbred C57BL; Mice, Knockout; Peroxisome Proliferator-Activated Receptors; Propionates; Triazoles | 2008 |
Correlation between plasma levels of 7alpha-hydroxy-4-cholesten-3-one and cholesterol 7alpha-hydroxylation rates in vivo in hyperlipidemic patients.
Topics: Aged; Anticholesteremic Agents; Bezafibrate; Cholestenones; Cholesterol; Cholesterol 7-alpha-Hydroxylase; Cholestyramine Resin; Complement C4; Data Interpretation, Statistical; Female; Gemfibrozil; Humans; Hypercholesterolemia; Hyperlipidemias; Hypolipidemic Agents; Kinetics; Male; Middle Aged; Reference Standards; Simvastatin | 2008 |
On the mechanism for PPAR agonists to enhance ABCA1 gene expression.
Topics: Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Bezafibrate; Cell Line, Tumor; Fenofibrate; Fibroblasts; Gemfibrozil; Gene Expression Regulation; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Pioglitazone; PPAR delta; PPAR gamma; Propionates; Thiazoles; Thiazolidinediones; Triazoles | 2009 |
Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
Topics: Antirheumatic Agents; Bezafibrate; Biological Transport; Cell Line; Drug Interactions; Estradiol; Gemfibrozil; Humans; Hypolipidemic Agents; Kidney; Kinetics; Liver-Specific Organic Anion Transporter 1; Organic Anion Transporters; Rifamycins | 2010 |
Fibrate use in diabetes: new concepts.
Topics: Bezafibrate; Cardiovascular Diseases; Diabetes Mellitus; Fenofibrate; Fibric Acids; Gemfibrozil; Humans; Hypolipidemic Agents | 2011 |
Toxicity of mixtures of perfluorooctane sulphonic acid with chlorinated chemicals and lipid regulators.
Topics: Alkanesulfonic Acids; Anti-Infective Agents, Local; Bezafibrate; Chlorophenols; Chlorophyta; Complex Mixtures; Drug Synergism; Fluorocarbons; Gemfibrozil; Hypolipidemic Agents; Lethal Dose 50; Mutagens; Surface-Active Agents; Triclosan; Water Pollutants, Chemical | 2012 |
Fibrates and fish oil, but not corn oil, up-regulate the expression of the cholesteryl ester transfer protein (CETP) gene.
Topics: Animals; Bezafibrate; Cholesterol Ester Transfer Proteins; Combined Modality Therapy; Corn Oil; Crosses, Genetic; Dietary Supplements; Female; Fenofibrate; Fibric Acids; Fish Oils; Gemfibrozil; Hypertriglyceridemia; Hypolipidemic Agents; Liver; Male; Mice, Transgenic; Random Allocation; RNA, Messenger; Up-Regulation | 2014 |
Enzymatic characterization of ELOVL1, a key enzyme in very long-chain fatty acid synthesis.
Topics: Acetyltransferases; Adrenoleukodystrophy; Bezafibrate; Enzyme Inhibitors; Fatty Acid Elongases; Fatty Acids; Fibroblasts; Gemfibrozil; HEK293 Cells; Humans; Hypolipidemic Agents; Kinetics; Microsomes; Transfection | 2015 |
Fibrates inhibit the apoptosis of Batten disease lymphoblast cells via autophagy recovery and regulation of mitochondrial membrane potential.
Topics: Apoptosis; Autophagy; Bezafibrate; Cells, Cultured; Fenofibrate; Gemfibrozil; Humans; Lymphocytes; Membrane Glycoproteins; Membrane Potential, Mitochondrial; Mitochondria; Molecular Chaperones; Neuronal Ceroid-Lipofuscinoses; Neuroprotective Agents; Oxidative Stress; PPAR alpha | 2016 |
Evaluation of the simultaneous removal of recalcitrant drugs (bezafibrate, gemfibrozil, indomethacin and sulfamethoxazole) and biodegradable organic matter from synthetic wastewater by electro-oxidation coupled with a biological system.
Topics: Bezafibrate; Bioreactors; Boron; Diamond; Electrodes; Electrolysis; Gemfibrozil; Indomethacin; Oxidation-Reduction; Sulfamethoxazole; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical | 2016 |
Degradation of lipid regulators by the UV/chlorine process: Radical mechanisms, chlorine oxide radical (ClO
Topics: Ammonia; Bezafibrate; Chlorine; Chlorine Compounds; Clofibric Acid; Disinfection; Gemfibrozil; Halogenation; Hydroxyl Radical; Hypolipidemic Agents; Kinetics; Oxidation-Reduction; Photolysis; Ultraviolet Rays; Vibrio; Waste Disposal, Fluid; Water Pollutants, Chemical; Water Purification | 2018 |
[A new attempt with lipoprotein lipase agonists in the treatment of nonalcoholic steatohepatitis].
Topics: Bezafibrate; Biopsy; Carboxylic Acids; Case-Control Studies; Computational Biology; Enzyme Activators; Gemfibrozil; Glycyrrhizic Acid; Humans; Lipid Metabolism; Lipoprotein Lipase; Non-alcoholic Fatty Liver Disease; Oligonucleotide Array Sequence Analysis; Scavenger Receptors, Class E | 2019 |