gemcitabine has been researched along with zidovudine in 13 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.69) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Björck, L; Clausen, AR; Piskur, J; Sandrini, MP; Shannon, O | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Celewicz, L; Kleczewska, N; Liberska, J; Ruszkowski, P; Singh, A; Trznadel, R | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Bianchi, V; Borella, S; Calderazzo, F; Chieco Bianchi, L; Ferraro, P; Reichard, P | 1 |
| Cinatl, J; Doerr, HW; Gröschel, B; Höver, G; Kaufmann, A; Loves, WJ; Noordhuis, P; Peters, GJ | 1 |
| Aarestrup, FM; Clausen, AR; Munch-Petersen, B; On, SL; Piskur, J; Sandrini, MP | 1 |
| Al Meani, SA; Clausen, AR; Piskur, J | 1 |
| Hoshino, T; Kodama, R; Mizushima, T; Moritomo, S; Namba, T | 1 |
1 review(s) available for gemcitabine and zidovudine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
12 other study(ies) available for gemcitabine and zidovudine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Deoxyribonucleoside kinases activate nucleoside antibiotics in severely pathogenic bacteria.
Topics: Animals; Anti-Bacterial Agents; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphotransferases (Alcohol Group Acceptor); Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus pyogenes | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Synthesis and in vitro anticancer activity of new gemcitabine-nucleoside analogue dimers containing methyltriazole or ester-methyltriazole linker.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Deoxycytidine; Dimerization; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Esters; Gemcitabine; Humans; Molecular Structure; Nucleosides; Structure-Activity Relationship; Triazoles | 2019 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Inhibition of ribonucleotide reductase by 2'-substituted deoxycytidine analogs: possible application in AIDS treatment.
Topics: Acquired Immunodeficiency Syndrome; Antiviral Agents; Cells, Cultured; Cytidine; Deoxycytidine; Gemcitabine; Humans; Hydroxyurea; In Vitro Techniques; Prodrugs; Ribonucleotide Reductases; Zidovudine | 1994 |
3'-Azido-2',3'-dideoxythymidine induced deficiency of thymidine kinases 1, 2 and deoxycytidine kinase in H9 T-lymphoid cells.
Topics: Adenosine Triphosphate; Anti-HIV Agents; Blotting, Western; Cytidine Triphosphate; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance, Microbial; Gemcitabine; HIV-1; Humans; RNA, Messenger; T-Lymphocytes; Thymidine Kinase; Uridine Triphosphate; Zidovudine | 2002 |
Nucleoside analogues are activated by bacterial deoxyribonucleoside kinases in a species-specific manner.
Topics: Anti-Bacterial Agents; Bacteria; Biotransformation; Cloning, Molecular; Deoxycytidine; DNA, Bacterial; Escherichia coli; Gemcitabine; Kinetics; Microbial Sensitivity Tests; Nucleosides; Phosphotransferases (Alcohol Group Acceptor); Phylogeny; Recombinant Proteins; Species Specificity; Thymidine Kinase; Zidovudine | 2007 |
Pasteurella multocida thymidine kinase 1 efficiently activates pyrimidine nucleoside analogs.
Topics: Antimetabolites, Antineoplastic; Deoxycytidine; Deoxyuridine; Escherichia coli; Gemcitabine; Microbial Sensitivity Tests; Pasteurella multocida; Pyrimidine Nucleosides; Thymidine Kinase; Zidovudine | 2010 |
Zidovudine, an anti-viral drug, resensitizes gemcitabine-resistant pancreatic cancer cells to gemcitabine by inhibition of the Akt-GSK3β-Snail pathway.
Topics: Animals; Antimetabolites, Antineoplastic; Antiviral Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Survival; Deoxycytidine; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Gemcitabine; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Pancreatic Neoplasms; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Small Interfering; Snail Family Transcription Factors; Transcription Factors; Up-Regulation; Xenograft Model Antitumor Assays; Zidovudine | 2015 |