Page last updated: 2024-08-24

gemcitabine and warfarin

gemcitabine has been researched along with warfarin in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's9 (50.00)29.6817
2010's5 (27.78)24.3611
2020's3 (16.67)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kinikar, SA; Kolesar, JM1
Davis, MA; Hough, A; Lawrence, TS; Rehemtulla, A1
Czarnecki, A; Kilgour-Christie, J1
Löhr, M; Müller, H; Nakchbandi, IA; Nakchbandi, W; Singer, MV1
Lohr, JM; Müller, H; Nakchbandi, IA; Nakchbandi, W; Singer, MV1
Saif, MW; Wasif, N1
Altman, RB; Brunak, S; Hansen, NT1
Dakeshita, H; Kinoshita, M; Morita, A; Nomata, K; Ogawa, M; Ozeki, A; Tsuruta, T; Yoshioka, H1
Bhuniya, S; Han, JH; Jeon, HM; Kang, C; Kim, JS; Lee, JH; Maiti, S; Park, N1
Brekken, RA; Dellinger, MT; Dineen, SP; Haaland, G; Kirane, A; Lorens, JB; Ludwig, KF; Micklem, D; Ranaweera, R; Sandal, T; Sorrelle, N; Toombs, JE; Wang, M1
Feuz, L; Gee, ME; Krajewski, KC; Kurtzhalts, K1
Bottinor, W; Das, S; Nunnery, S1
Bai, Y; Chen, D; Deng, J; Guo, H; Guo, Y; Lan, J; Liu, X; Wang, J; Xiao, Y; Zhang, Q; Zhu, H1
Couturier, F; Graff, V; Herrscher, H; Moussouni, M1

Reviews

1 review(s) available for gemcitabine and warfarin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

17 other study(ies) available for gemcitabine and warfarin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Identification of a gemcitabine-warfarin interaction.
    Pharmacotherapy, 1999, Volume: 19, Issue:11

    Topics: Anticoagulants; Antimetabolites, Antineoplastic; Deoxycytidine; Drug Interactions; Gemcitabine; Half-Life; Humans; Liver; Male; Middle Aged; Warfarin

1999
The role of apoptosis in 2',2'-difluoro-2'-deoxycytidine (gemcitabine)-mediated radiosensitization.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2001, Volume: 7, Issue:2

    Topics: Apoptosis; Caspase 3; Caspase Inhibitors; Caspases; Cell Survival; Cobalt Radioisotopes; Colonic Neoplasms; Coumarins; Deoxycytidine; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Radiation; Electrophoresis, Gel, Pulsed-Field; Enzyme Activation; Gemcitabine; Head and Neck Neoplasms; Humans; Lung Neoplasms; Oligopeptides; Radiation-Sensitizing Agents; Tumor Cells, Cultured

2001
Gemcitabine and the interaction with anticoagulants.
    The Lancet. Oncology, 2002, Volume: 3, Issue:8

    Topics: Anticoagulants; Antimetabolites, Antineoplastic; Deoxycytidine; Drug Interactions; Female; Gemcitabine; Humans; Male; Monitoring, Physiologic; Registries; Risk Assessment; Warfarin

2002
Effects of low-dose warfarin and regional chemotherapy on survival in patients with pancreatic carcinoma.
    Scandinavian journal of gastroenterology, 2006, Volume: 41, Issue:9

    Topics: Antibiotics, Antineoplastic; Anticoagulants; Carcinoma; Deoxycytidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Gemcitabine; Humans; Immunosuppressive Agents; Injections, Intra-Arterial; Male; Middle Aged; Mitomycin; Pancreatic Neoplasms; Retrospective Studies; Ribonucleotide Reductases; Survival Rate; Treatment Outcome; Warfarin

2006
Prospective study on warfarin and regional chemotherapy in patients with pancreatic carcinoma.
    Journal of gastrointestinal and liver diseases : JGLD, 2008, Volume: 17, Issue:3

    Topics: Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Cancer, Regional Perfusion; Deoxycytidine; Drug Therapy, Combination; Female; Gemcitabine; Humans; Male; Middle Aged; Mitomycin; Pancreatic Neoplasms; Prospective Studies; Warfarin

2008
Interaction between capecitabine and gemcitabine with warfarin in a patient with pancreatic cancer.
    JOP : Journal of the pancreas, 2008, Nov-03, Volume: 9, Issue:6

    Topics: Adenocarcinoma; Aged; Blood Coagulation; Capecitabine; Cholangiopancreatography, Endoscopic Retrograde; Deoxycytidine; Drug Interactions; Female; Fluorouracil; Gemcitabine; Humans; International Normalized Ratio; Pancreatic Neoplasms; Prothrombin Time; Stents; Warfarin

2008
Generating genome-scale candidate gene lists for pharmacogenomics.
    Clinical pharmacology and therapeutics, 2009, Volume: 86, Issue:2

    Topics: Anticoagulants; Antineoplastic Agents; Area Under Curve; Carboplatin; Deoxycytidine; Gefitinib; Gemcitabine; Gene Expression Regulation; Genes; Genome, Human; Humans; Oligonucleotide Array Sequence Analysis; Pharmacogenetics; Quinazolines; Warfarin

2009
[A case of a patient with bladder cancer who received warfarin and showed a significantly prolonged PT-INR after gemcitabine and cisplatin combination therapy].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2012, Volume: 39, Issue:2

    Topics: Aged; Anticoagulants; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Deoxycytidine; Edema; Female; Gemcitabine; Humans; International Normalized Ratio; Leg; Prothrombin; Thrombophlebitis; Urinary Bladder Neoplasms; Warfarin

2012
Gemcitabine-coumarin-biotin conjugates: a target specific theranostic anticancer prodrug.
    Journal of the American Chemical Society, 2013, Mar-20, Volume: 135, Issue:11

    Topics: Antineoplastic Agents; Biotin; Cell Line, Tumor; Cell Survival; Coumarins; Deoxycytidine; Drug Delivery Systems; Fluorescent Dyes; Gemcitabine; Humans; Neoplasms; Prodrugs; Sulfhydryl Compounds

2013
Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis.
    Cancer research, 2015, Sep-15, Volume: 75, Issue:18

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Axl Receptor Tyrosine Kinase; Carcinoma, Pancreatic Ductal; Cell Division; Cell Line, Tumor; Cell Movement; Deoxycytidine; Disease Progression; Drug Synergism; Epithelial-Mesenchymal Transition; Female; Gemcitabine; Gene Knockdown Techniques; Humans; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, SCID; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Pancreatic Neoplasms; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA, Small Interfering; Signal Transduction; Specific Pathogen-Free Organisms; Warfarin; Xenograft Model Antitumor Assays

2015
Evidence of a clinically significant interaction between warfarin and intravesical gemcitabine.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2016, Oct-01, Volume: 73, Issue:19

    Topics: Administration, Intravesical; Aged, 80 and over; Anticoagulants; Antimetabolites, Antineoplastic; BCG Vaccine; Carcinoma, Transitional Cell; Deoxycytidine; Drug Interactions; Enoxaparin; Gemcitabine; Humans; International Normalized Ratio; Male; Urinary Bladder Neoplasms; Venous Thrombosis; Warfarin

2016
Cardiac Masses in a Patient With Pancreatic Adenocarcinoma and a History of Breast Carcinoma.
    JAMA oncology, 2020, 06-01, Volume: 6, Issue:6

    Topics: Adenocarcinoma; Albumins; Anticoagulants; Breast Neoplasms; Deoxycytidine; Female; Gemcitabine; Heart Ventricles; Humans; Magnetic Resonance Imaging; Middle Aged; Paclitaxel; Pancreatic Neoplasms; Thrombosis; Warfarin

2020
The anti-dysenteric drug fraxetin enhances anti-tumor efficacy of gemcitabine and suppresses pancreatic cancer development by antagonizing STAT3 activation.
    Aging, 2021, 07-28, Volume: 13, Issue:14

    Topics: Animals; Apoptosis; Cell Line, Tumor; Coumarins; Deoxycytidine; Epithelial-Mesenchymal Transition; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Reactive Oxygen Species; Signal Transduction; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2021
Drug Interactions Causing Warfarin Overdose in a Patient with Pancreatic Cancer: A Case Report.
    Chemotherapy, 2023, Volume: 68, Issue:2

    Topics: Adenocarcinoma; Albumins; Antineoplastic Combined Chemotherapy Protocols; Cytochrome P-450 Enzyme System; Drug Interactions; Gemcitabine; Humans; Male; Paclitaxel; Pancreatic Neoplasms; Plant Extracts; Warfarin

2023