Compounds > gemcitabine
Page last updated: 2024-08-24

gemcitabine and quercetin

gemcitabine has been researched along with quercetin in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's1 (7.69)29.6817
2010's8 (61.54)24.3611
2020's3 (23.08)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL1
Holzer, G; Karlseder, J; Orel, L; Simon, MM; Sliutz, G; Tempfer, C1
Angst, E; Chen, M; Eibl, G; Go, VL; Hines, OJ; King, J; Li, G; Lu, QY; Lu, X; Moro, A; Park, JL; Reber, HA1
Chun, HJ; Hyun, JJ; Jeen, YT; Keum, B; Kim, CD; Lee, HS; Seo, YS; Um, SH1
Hur, GY; In, KH; Kang, KH; Kim, JH; Lee, EJ; Lee, SH; Lee, SY; Min, KH; Shim, JJ; Shin, C1
Cao, C; Luo, J; Mo, W; Ran, Y; Sun, L; Yang, Z1
Kim, JH; Kim, SJ; Lee, J1
Bauer, N; Fan, P; Gao, C; Gladkich, J; Gross, W; Herr, I; Liu, L; Mattern, J; Schemmer, P; Xiao, X; Yin, Y; Zhang, Y; Zhao, Z1
Biondi, M; Botti, G; Fusco, S; Iaffaioli, RV; Mayol, L; Quagliariello, V; Serri, C1
Gao, LF; Han, J; Li, XL; Liu, QY; Liu, ZJ; Wang, XH; Xu, W1
Benkirane-Jessel, N; Chalhoub, S; Fuhrmann, G; Hassan, S; Idoux Gillet, Y; Peluso, J; Rochel, N; Ubeaud-Sequier, G1

Reviews

1 review(s) available for gemcitabine and quercetin

ArticleYear
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
    Medicinal research reviews, 2021, Volume: 41, Issue:1

    Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization

2021

Other Studies

12 other study(ies) available for gemcitabine and quercetin

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Drug resistance against gemcitabine and topotecan mediated by constitutive hsp70 overexpression in vitro: implication of quercetin as sensitiser in chemotherapy.
    British journal of cancer, 1996, Volume: 74, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Cell Division; Deoxycytidine; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fibrosarcoma; Gemcitabine; HSP70 Heat-Shock Proteins; Humans; Mice; Quercetin; Topotecan; Transfection; Tumor Cells, Cultured

1996
The flavonoid quercetin inhibits pancreatic cancer growth in vitro and in vivo.
    Pancreas, 2013, Volume: 42, Issue:2

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Humans; Luciferases, Firefly; Luminescent Measurements; Mice; Mice, Nude; Pancreatic Neoplasms; Quercetin; Time Factors; Transduction, Genetic; Tumor Burden; Xenograft Model Antitumor Assays

2013
Expression of heat shock protein 70 modulates the chemoresponsiveness of pancreatic cancer.
    Gut and liver, 2013, Volume: 7, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Autophagy; Caspase 3; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; HSP70 Heat-Shock Proteins; Humans; Microtubule-Associated Proteins; Pancreatic Neoplasms; Quercetin

2013
Quercetin Enhances Chemosensitivity to Gemcitabine in Lung Cancer Cells by Inhibiting Heat Shock Protein 70 Expression.
    Clinical lung cancer, 2015, Volume: 16, Issue:6

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Apoptosis; Biomarkers, Pharmacological; Caspases; Cell Line, Tumor; Deoxycytidine; Gemcitabine; Gene Expression Regulation; HSP70 Heat-Shock Proteins; Humans; Lung Neoplasms; Quercetin

2015
Quercetin Mediates β-Catenin in Pancreatic Cancer Stem-Like Cells.
    Pancreas, 2015, Volume: 44, Issue:8

    Topics: Antimetabolites, Antineoplastic; Antioxidants; beta Catenin; Biomarkers, Tumor; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; Gemcitabine; Humans; Microscopy, Confocal; Neoplastic Stem Cells; Pancreatic Neoplasms; Quercetin; Spheroids, Cellular

2015
Quercetin-3-O-glucoside suppresses pancreatic cancer cell migration induced by tumor-deteriorated growth factors in vitro.
    Oncology reports, 2016, Volume: 35, Issue:4

    Topics: Cell Line, Tumor; Cell Movement; Databases, Genetic; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Fibroblast Growth Factor 2; Flavonoids; Gemcitabine; Gene Expression Regulation, Neoplastic; Glucosides; Humans; In Vitro Techniques; Pancreatic Neoplasms; Quercetin; Transforming Growth Factor beta; Vascular Endothelial Growth Factor A

2016
Continuous exposure of pancreatic cancer cells to dietary bioactive agents does not induce drug resistance unlike chemotherapy.
    Cell death & disease, 2016, 06-02, Volume: 7, Issue:6

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Carcinogenesis; Cell Line, Tumor; Cell Survival; Clone Cells; Deoxycytidine; Diet; Disease Progression; Drug Resistance, Neoplasm; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Isothiocyanates; Neoplastic Stem Cells; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Phytochemicals; Quercetin; Sulfoxides

2016
Combination therapy for the treatment of pancreatic cancer through hyaluronic acid-decorated nanoparticles loaded with quercetin and gemcitabine: A preliminary in vitro study.
    Journal of cellular physiology, 2019, Volume: 234, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Carriers; Drug Synergism; Gemcitabine; Humans; Hyaluronic Acid; Nanoparticles; Pancreatic Neoplasms; Quercetin

2019
Quercetin induces apoptosis and enhances gemcitabine therapeutic efficacy against gemcitabine-resistant cancer cells.
    Anti-cancer drugs, 2020, Volume: 31, Issue:7

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle Checkpoints; Cell Line, Tumor; Cyclin D1; Deoxycytidine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Hep G2 Cells; Humans; Liver Neoplasms; Pancreatic Neoplasms; Quercetin; Tumor Suppressor Protein p53

2020
Quercetin potentializes the respective cytotoxic activity of gemcitabine or doxorubicin on 3D culture of AsPC-1 or HepG2 cells, through the inhibition of HIF-1α and MDR1.
    PloS one, 2020, Volume: 15, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; ATP Binding Cassette Transporter, Subfamily B; Cell Hypoxia; Deoxycytidine; Doxorubicin; Drug Resistance, Neoplasm; Gemcitabine; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms; Pancreatic Neoplasms; Quercetin; Tumor Microenvironment

2020