gemcitabine has been researched along with oligonucleotides in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brandl, M; Massing, U; Moog, R; Schubert, R; Unger, C | 1 |
| Gioffre, C; Gmeiner, WH; Goldwasser, F; Hertel, LW; Kohlhagen, G; Pommier, Y; Pon, RT; Pourquier, P; Urasaki, Y; Yu, S | 1 |
| Duan, Y; Duan, Z; Lamendola, DE; Naeem, R; Penson, RT; Seiden, MV; Yusuf, RZ | 1 |
| Belt, R; Dow, E; Figueroa, JA; Geary, R; George, S; Holmlund, J; Leonardo, J; McCachren, S; Miller, GL; Modiano, M; Oliver, JW; Otterson, GA; Ritch, P; Valdivieso, M; Villalona-Calero, MA | 1 |
| Addis, A; Balsari, A; Belluco, S; Menard, S; Petrangolini, G; Pratesi, G; Rossini, A; Rumio, C; Selleri, S; Tortoreto, M | 1 |
| Booker, AJ; Christensen, LA; Finch, RA; Vasquez, KM | 1 |
| Agrawal, S; Kandimalla, ER; Rayburn, ER; Wang, H; Wang, W; Zhang, R | 1 |
| Li, M; Rayburn, ER; Wang, H; Wang, W; Zhang, R; Zhang, Z | 1 |
| Lipton, L; McCoy, S; McGreivy, J; Price, TJ; Rosenthal, MA; Sun, YN | 1 |
| Adewoye, AH; Desai, J; Johnson, J; Kotasek, D; McCoy, S; Price, T; Siu, LL; Sun, YN; Tebbutt, N; Welch, S | 1 |
| Chalasani, P; Jolivet, J; Kurtin, S; Mahadevan, D; Pretzinger, C; Ramanathan, RK; Rensvold, D; Von Hoff, DD; Weiss, GJ | 1 |
| Boulware, SB; Christensen, LA; Coghlan, L; Finch, RA; Thames, H; Vasquez, KM | 1 |
| Aoyama, T; Atsumi, Y; Kobayashi, S; Miyagi, Y; Morimoto, M; Morinaga, S; Murakawa, M; Nakamura, Y; Ueno, M; Yamaoku, K; Yokose, T | 1 |
| Guo, X; Ingale, SA; Leonard, P; Seela, F | 1 |
4 trial(s) available for gemcitabine and oligonucleotides
| Article | Year |
|---|---|
A phase I/II study of LY900003, an antisense inhibitor of protein kinase C-alpha, in combination with cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cohort Studies; Deoxycytidine; Enzyme Inhibitors; Female; Follow-Up Studies; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Oligodeoxyribonucleotides, Antisense; Oligonucleotides; Oligonucleotides, Antisense; Protein Kinase C; Protein Kinase C-alpha; Thionucleotides; Treatment Outcome | 2004 |
Safety and pharmacokinetics of motesanib in combination with gemcitabine for the treatment of patients with solid tumours.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Deoxycytidine; Drug Administration Schedule; Female; Gemcitabine; Humans; Indoles; Male; Middle Aged; Neoplasms; Niacinamide; Oligonucleotides | 2008 |
Safety and pharmacokinetics of motesanib in combination with gemcitabine and erlotinib for the treatment of solid tumors: a phase 1b study.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Cohort Studies; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Erlotinib Hydrochloride; Female; Gemcitabine; Humans; Hypertension; Indoles; Male; Metabolic Clearance Rate; Middle Aged; Nausea; Neoplasms; Niacinamide; Oligonucleotides; Quinazolines; Treatment Outcome; Venous Thrombosis; Vomiting; Young Adult | 2011 |
Phase I trial of AEG35156 an antisense oligonucleotide to XIAP plus gemcitabine in patients with metastatic pancreatic ductal adenocarcinoma.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Carcinoma, Pancreatic Ductal; Combined Modality Therapy; Deoxycytidine; Female; Follow-Up Studies; Gemcitabine; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Oligonucleotides; Pancreatic Neoplasms; Survival Rate; Treatment Outcome; X-Linked Inhibitor of Apoptosis Protein | 2013 |
10 other study(ies) available for gemcitabine and oligonucleotides
| Article | Year |
|---|---|
Effect of nucleoside analogues and oligonucleotides on hydrolysis of liposomal phospholipids.
Topics: Anions; Antimetabolites, Antineoplastic; Buffers; Deoxycytidine; Gemcitabine; Hydrogen-Ion Concentration; Hydrolysis; Lipid Bilayers; Liposomes; Lysophospholipids; Nucleosides; Oligonucleotides | 2000 |
Gemcitabine (2',2'-difluoro-2'-deoxycytidine), an antimetabolite that poisons topoisomerase I.
Topics: Animals; Antimetabolites, Antineoplastic; Deoxycytidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gemcitabine; Humans; Mice; Models, Chemical; Oligonucleotides; Time Factors; Topoisomerase I Inhibitors; Tumor Cells, Cultured | 2002 |
Overexpression of MAGE/GAGE genes in paclitaxel/doxorubicin-resistant human cancer cell lines.
Topics: Antigens, Neoplasm; Blotting, Northern; Calcium-Binding Proteins; Cell Cycle Proteins; Cell Line, Tumor; Chromosomes, Human, X; Cluster Analysis; Deoxycytidine; DNA Primers; DNA, Complementary; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Female; Gemcitabine; Humans; Immunotherapy; Male; Multigene Family; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Oligonucleotides; Paclitaxel; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Testis; Time Factors; Transfection | 2003 |
Therapeutic synergism of gemcitabine and CpG-oligodeoxynucleotides in an orthotopic human pancreatic carcinoma xenograft.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Combined Modality Therapy; CpG Islands; Deoxycytidine; DNA-Binding Proteins; Drug Synergism; Female; Gemcitabine; Humans; Immunotherapy; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Oligonucleotides; Pancreatic Neoplasms; Receptors, Cell Surface; Toll-Like Receptor 9; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2005 |
Targeting oncogenes to improve breast cancer chemotherapy.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Base Sequence; Breast Neoplasms; Cell Adhesion; Cell Growth Processes; Cell Line, Tumor; Deoxycytidine; DNA Damage; Drug Synergism; Gemcitabine; Gene Expression; Genes, myc; Humans; Molecular Sequence Data; Oligonucleotides; Transcription, Genetic | 2006 |
Chemotherapy and chemosensitization of non-small cell lung cancer with a novel immunomodulatory oligonucleotide targeting Toll-like receptor 9.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Deoxycytidine; Drug Tolerance; Female; Gemcitabine; Glutamates; Guanine; Humans; Immunologic Factors; Lung Neoplasms; Male; Mice; Mice, Nude; Oligonucleotides; Pemetrexed; RNA, Messenger; Toll-Like Receptor 9; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2006 |
Experimental therapy of prostate cancer with an immunomodulatory oligonucleotide: effects on tumor growth, apoptosis, proliferation, and potentiation of chemotherapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Deoxycytidine; Docetaxel; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Immunologic Factors; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Oligonucleotides; Phosphatidylethanolamines; Prostatic Neoplasms; RNA, Messenger; Taxoids; Toll-Like Receptor 9 | 2006 |
Triplex-forming oligonucleotides targeting c-MYC potentiate the anti-tumor activity of gemcitabine in a mouse model of human cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Chromatin Immunoprecipitation; Colonic Neoplasms; Deoxycytidine; DNA, Neoplasm; Drug Synergism; Female; Gemcitabine; Humans; Mice; Mice, Nude; Oligonucleotides; Proto-Oncogene Proteins c-myc; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2014 |
Locked Nucleic Acid In Situ Hybridization Analysis of MicroRNA-21 Predicts Clinical Outcome in Patients After Resection for Pancreatic Cancer Treated with Adjuvant Gemcitabine Monotherapy.
Topics: Aged; Carcinoma, Pancreatic Ductal; Chemotherapy, Adjuvant; Deoxycytidine; Drug Resistance, Neoplasm; Female; Gemcitabine; Humans; In Situ Hybridization; Male; MicroRNAs; Middle Aged; Oligonucleotides; Pancreatic Neoplasms; Prognosis; Survival Analysis; Treatment Outcome | 2016 |
Gemcitabine, Pyrrologemcitabine, and 2'-Fluoro-2'-Deoxycytidines: Synthesis, Physical Properties, and Impact of Sugar Fluorination on Silver Ion Mediated Base Pairing.
Topics: Base Pairing; Deoxycytidine; Gemcitabine; Halogenation; Ions; Magnetic Resonance Spectroscopy; Oligonucleotides; Ribose; Silver; Spectrometry, Fluorescence | 2017 |