Page last updated: 2024-08-24

gemcitabine and mocetinostat

gemcitabine has been researched along with mocetinostat in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (66.67)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Brady, H; Heise, C; Kelter, G; Maier, A; Richard, N; Sung, V1
Batte, K; Bid, HK; Braggio, D; Casadei, L; Choy, E; Iwenofu, OH; Koller, D; Lev, D; Lopez, G; Pollock, R; Strohecker, A; Yu, P; Zewdu, A1
Alcindor, T; Chan, E; Chao, R; Chiorean, EG; Gabrail, NY; Hurwitz, H; O'Dwyer, PJ; Potvin, D1
Li, N; Qi, Y; Yu, D; Zhan, J; Zhang, G; Zhao, Q1

Trials

1 trial(s) available for gemcitabine and mocetinostat

ArticleYear
Phase I/II study of mocetinostat in combination with gemcitabine for patients with advanced pancreatic cancer and other advanced solid tumors.
    Cancer chemotherapy and pharmacology, 2018, Volume: 81, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cohort Studies; Deoxycytidine; Endpoint Determination; Female; Gemcitabine; Histone Deacetylase Inhibitors; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Pancreatic Neoplasms; Pyrimidines; Treatment Outcome

2018

Other Studies

5 other study(ies) available for gemcitabine and mocetinostat

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Histone deacetylase inhibitor MGCD0103 synergizes with gemcitabine in human pancreatic cells.
    Cancer science, 2011, Volume: 102, Issue:6

    Topics: Apoptosis; Benzamides; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Synergism; Gemcitabine; Gene Expression; Histone Deacetylase Inhibitors; Humans; Immunoblotting; Pancreas; Pancreatic Neoplasms; Pyrimidines

2011
Mocetinostat combined with gemcitabine for the treatment of leiomyosarcoma: Preclinical correlates.
    PloS one, 2017, Volume: 12, Issue:11

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Cell Division; Cell Line, Tumor; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Leiomyosarcoma; Pyrimidines

2017
Synergistic ferroptosis-gemcitabine chemotherapy of the gemcitabine loaded carbonaceous nanozymes to enhance the treatment and magnetic resonance imaging monitoring of pancreatic cancer.
    Acta biomaterialia, 2022, 04-01, Volume: 142

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Tumor; Deoxycytidine; Ferroptosis; Gemcitabine; Glutathione Peroxidase; Humans; Magnetic Resonance Imaging; Pancreatic Neoplasms; Peroxidase; Reactive Oxygen Species

2022