Page last updated: 2024-08-24

gemcitabine and deoxyguanosine

gemcitabine has been researched along with deoxyguanosine in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's4 (66.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Björck, L; Clausen, AR; Piskur, J; Sandrini, MP; Shannon, O1
Chapman, AJ; Chubb, S; Gandhi, V; Hertel, LW; Huang, P; Mineishi, S; Nowak, BJ; Plunkett, W; Yang, Y1
Lin, CS; Tsai, CM; Wang, LS; Wei, YH1
Hazra, S; Konrad, M; Lavie, A; Ort, S; Sabini, E1
Adema, AD; Honeywell, RJ; Peters, GJ; van der Born, K1
Ackermann, BL; Bones, AM; Freeman, AB; Jones, BR; Lutzke, BS; Pratt, SE; Schultz, GA; Wickremsinhe, ER1

Other Studies

6 other study(ies) available for gemcitabine and deoxyguanosine

ArticleYear
Deoxyribonucleoside kinases activate nucleoside antibiotics in severely pathogenic bacteria.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Deoxycytidine; Female; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Sequence Data; Nucleosides; Phosphotransferases (Alcohol Group Acceptor); Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus pyogenes

2007
Difluorodeoxyguanosine: cytotoxicity, metabolism, and actions on DNA synthesis in human leukemia cells.
    Seminars in oncology, 1995, Volume: 22, Issue:4 Suppl 11

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Arabinonucleosides; Base Sequence; Cricetinae; Deoxycytidine; Deoxyguanosine; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Gemcitabine; Humans; Leukemia; Molecular Sequence Data; Nucleotides; Peptide Chain Elongation, Translational; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); RNA, Neoplasm; Structure-Activity Relationship; Tumor Cells, Cultured

1995
Low copy number and low oxidative damage of mitochondrial DNA are associated with tumor progression in lung cancer tissues after neoadjuvant chemotherapy.
    Interactive cardiovascular and thoracic surgery, 2008, Volume: 7, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Cisplatin; Deoxycytidine; Deoxyguanosine; Disease Progression; DNA Damage; DNA, Mitochondrial; Down-Regulation; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Neoadjuvant Therapy; Oxidative Stress; Pneumonectomy; Retrospective Studies; Treatment Outcome

2008
Extending thymidine kinase activity to the catalytic repertoire of human deoxycytidine kinase.
    Biochemistry, 2009, Feb-17, Volume: 48, Issue:6

    Topics: Adenosine Diphosphate; Biocatalysis; Crystallography, X-Ray; Cytarabine; Deoxyadenosines; Deoxycytidine; Deoxycytidine Kinase; Deoxyguanosine; Gemcitabine; Humans; Kinetics; Mutant Proteins; Mutation; Protein Structure, Secondary; Static Electricity; Substrate Specificity; Thymidine; Thymidine Kinase

2009
Cell cycle effects and increased adduct formation by temozolomide enhance the effect of cytotoxic and targeted agents in lung cancer cell lines.
    Journal of chemotherapy (Florence, Italy), 2009, Volume: 21, Issue:3

    Topics: Animals; Antineoplastic Agents, Alkylating; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Dacarbazine; Deoxycytidine; Deoxyguanosine; DNA Adducts; DNA Methylation; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Mice; O(6)-Methylguanine-DNA Methyltransferase; Paclitaxel; Piperidines; Pyridines; Temozolomide

2009
Quantification of gemcitabine incorporation into human DNA by LC/MS/MS as a surrogate measure for target engagement.
    Analytical chemistry, 2010, Aug-01, Volume: 82, Issue:15

    Topics: Animals; Antimetabolites, Antineoplastic; Cell Line, Tumor; Chromatography, High Pressure Liquid; Deoxycytidine; Deoxyguanosine; DNA; Dogs; Gemcitabine; Humans; Spectrometry, Mass, Electrospray Ionization

2010