gemcitabine has been researched along with decitabine in 20 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 12 (60.00) | 24.3611 |
| 2020's | 1 (5.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bonnac, L; Clouser, CL; Daly, MB; Kim, B; Landman, SR; Mansky, LM; Patterson, SE; Rawson, JM; Reilly, CS; Roth, ME; Xie, J | 1 |
| Cournoyer, D; Eliopoulos, N; Momparler, RL | 1 |
| Beauséjour, C; Eliopoulos, N; Momparler, RL | 1 |
| Beauséjour, CM; Gagnon, J; Momparler, RL; Primeau, M | 1 |
| Crnogorac-Jurcevic, T; Donadelli, M; Lemoine, NR; Missiaglia, E; Palmieri, M; Scarpa, A | 1 |
| Ammerpohl, O; Fölsch, UR; Kalthoff, H; Koch, D; Müerköster, SS; Schäfer, H; Sipos, B; Tsao, MS; Werbing, V | 1 |
| Clouser, CL; Mansky, LM; Patterson, SE | 1 |
| Clouser, CL; Greggs, WM; Mansky, LM; Patterson, SE | 1 |
| Briggs, JE; Clouser, CL; Crankshaw, DL; Holtz, CM; Mansky, LM; Mullett, M; O'Sullivan, MG; Patterson, SE | 1 |
| Cass, CE; Damaraju, VL; Mowles, D; Ng, A; Tong, Z; Yao, S; Young, JD | 1 |
| Andersson, BS; Champlin, RE; Li, Y; Murray, D; Nieto, Y; Valdez, BC; Wang, G | 1 |
| Cogdill, AP; Cooper, ZA; Ferrone, CR; Fiedler, A; Frederick, DT; Garber, HR; Rosenberg, L; Thayer, SP; Wargo, JA; Warshaw, AL | 1 |
| Almgren, M; Baird, AM; Dockry, E; Ekström, TJ; Gray, SG; Hollywood, D; Meunier, A; Nikolaidis, G; O'Byrne, KJ; O'Kelly, F; Perry, AS | 1 |
| Bonnac, L; Clouser, CL; Mansky, LM; Patterson, SE | 1 |
| Fukuda, M; Hosokawa, M; Iwakawa, S; Masuda, A; Tanaka, S; Ueda, K | 1 |
| Chen, D; Cheng, M; Gao, Q; Jiang, Y; Li, J; Li, Y; Liang, Y; Lin, S; Liu, Z; Sheng, L; Wu, M; Zhang, H; Zhang, X; Zhang, Y; Zhu, F | 1 |
| Courcelle, M; Djaker, N; Palama, T; Sahli, F; Savarin, P; Spadavecchia, J | 1 |
2 review(s) available for gemcitabine and decitabine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Chemoprotection against cytosine nucleoside analogs using the human cytidine deaminase gene.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytarabine; Cytidine Deaminase; Decitabine; Deoxycytidine; Drug Resistance; Gemcitabine; Humans | 1999 |
18 other study(ies) available for gemcitabine and decitabine
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Synergistic reduction of HIV-1 infectivity by 5-azacytidine and inhibitors of ribonucleotide reductase.
Topics: Anti-HIV Agents; Azacitidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Ribonucleotide Reductases; Structure-Activity Relationship | 2016 |
Drug resistance to 5-aza-2'-deoxycytidine, 2',2'-difluorodeoxycytidine, and cytosine arabinoside conferred by retroviral-mediated transfer of human cytidine deaminase cDNA into murine cells.
Topics: 3T3 Cells; Animals; Antimetabolites; Antimetabolites, Antineoplastic; Azacitidine; Colony-Forming Units Assay; Cytarabine; Cytidine Deaminase; Decitabine; Deoxycytidine; DNA, Complementary; Drug Resistance; Enzyme Inhibitors; Fibroblasts; Gemcitabine; Gene Transfer Techniques; Genetic Vectors; Humans; Mice; Phenotype; Retroviridae; Tetrahydrouridine | 1998 |
Cytotoxic activity of 2',2'-difluorodeoxycytidine, 5-aza-2'-deoxycytidine and cytosine arabinoside in cells transduced with deoxycytidine kinase gene.
Topics: 3T3 Cells; Animals; Azacitidine; Cell Death; Cell Line; Cytarabine; Cytidine Deaminase; Decitabine; Deoxycytidine; Deoxycytidine Kinase; DNA, Complementary; Dose-Response Relationship, Drug; Gemcitabine; Genetic Vectors; Humans; Mice; Phenotype; Phosphorylation; Retroviridae; Thymidine Kinase; Tumor Cells, Cultured | 2002 |
Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Azacitidine; Cisplatin; Decitabine; Deoxycytidine; DNA Methylation; DNA Modification Methylases; Gemcitabine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Interferon-gamma; Interferons; Pancreatic Neoplasms; Signal Transduction | 2005 |
Role of myofibroblasts in innate chemoresistance of pancreatic carcinoma--epigenetic downregulation of caspases.
Topics: Animals; Apoptosis; Azacitidine; Carcinoma, Pancreatic Ductal; Caspases; Cell Line, Tumor; Cell Nucleus; Coculture Techniques; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Down-Regulation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Etoposide; Female; Fibroblasts; Gemcitabine; Humans; Mice; Mice, SCID; Pancreatic Neoplasms; STAT1 Transcription Factor; Transfection | 2008 |
Exploiting drug repositioning for discovery of a novel HIV combination therapy.
Topics: Anti-HIV Agents; Azacitidine; Decitabine; Deoxycytidine; Drug Interactions; Drug Therapy, Combination; Gemcitabine; HIV; HIV Infections; Humans; Mutation | 2010 |
Discovery of drugs that possess activity against feline leukemia virus.
Topics: Adenine; Animals; Antiviral Agents; Azacitidine; Cat Diseases; Cats; Decitabine; Deoxycytidine; Dose-Response Relationship, Drug; Gemcitabine; Leukemia Virus, Feline; Leukemia, Feline; Organophosphonates; Pyrrolidinones; Raltegravir Potassium; Retroviridae Infections; Tenofovir; Tumor Virus Infections | 2012 |
Activity of a novel combined antiretroviral therapy of gemcitabine and decitabine in a mouse model for HIV-1.
Topics: Animals; Anti-HIV Agents; Azacitidine; Body Weight; Cells, Cultured; Chemical and Drug Induced Liver Injury; Decitabine; Deoxycytidine; Drug Combinations; Drug Synergism; Female; Flow Cytometry; Gemcitabine; HIV-1; Humans; Liver; Lymph Nodes; Mice; Mice, Inbred C57BL; Murine Acquired Immunodeficiency Syndrome; Proviruses; Spleen; T-Lymphocytes; Transfection | 2012 |
Role of human nucleoside transporters in the uptake and cytotoxicity of azacitidine and decitabine.
Topics: Animals; Azacitidine; Carbon Radioisotopes; Decitabine; Deoxycytidine; Equilibrative Nucleoside Transporter 1; Gemcitabine; Humans; Membrane Transport Proteins; Oocytes; Saccharomyces cerevisiae; Tritium; Xenopus | 2012 |
Epigenetic modifiers enhance the synergistic cytotoxicity of combined nucleoside analog-DNA alkylating agents in lymphoma cell lines.
Topics: Antineoplastic Agents, Alkylating; Ataxia Telangiectasia Mutated Proteins; Azacitidine; Busulfan; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 2; Cytotoxins; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA Methyltransferase 3B; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Drug Synergism; Epigenesis, Genetic; Gemcitabine; Hematopoietic Stem Cell Transplantation; Humans; Hydroxamic Acids; Lymphoma; Melphalan; Protein Serine-Threonine Kinases; Transplantation Conditioning; Transplantation, Homologous; Tumor Suppressor Proteins | 2012 |
Targeting the MAGE A3 antigen in pancreatic cancer.
Topics: Adenocarcinoma; Antigens, Neoplasm; Azacitidine; Cell Line, Tumor; Chromatin Assembly and Disassembly; Cytokines; Decitabine; Deoxycytidine; DNA Methylation; Gemcitabine; Humans; Hydroxamic Acids; Immunotherapy; Male; Neoplasm Proteins; Pancreas; Pancreatic Neoplasms; Receptors, Antigen, T-Cell; T-Lymphocytes; Testis; Valproic Acid | 2012 |
Gemcitabine reactivates epigenetically silenced genes and functions as a DNA methyltransferase inhibitor.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Line, Tumor; CpG Islands; Decitabine; Deoxycytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Stability; Epigenesis, Genetic; Gemcitabine; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylase 1; Humans; Promoter Regions, Genetic; Tumor Suppressor Proteins; Vascular Endothelial Growth Factor Receptor-1 | 2012 |
Characterization of permeability, stability and anti-HIV-1 activity of decitabine and gemcitabine divalerate prodrugs.
Topics: Anti-HIV Agents; Azacitidine; Biological Availability; Caco-2 Cells; Cell Proliferation; Decitabine; Deoxycytidine; Drug Stability; Gemcitabine; Half-Life; HEK293 Cells; HIV-1; Humans; Hydrogen-Ion Concentration; Permeability; Prodrugs | 2014 |
Monophosphorylation by deoxycytidine kinase affects apparent cellular uptake of decitabine in HCT116 colon cancer cells.
Topics: Antimetabolites, Antineoplastic; Azacitidine; Camptothecin; Colonic Neoplasms; Cytarabine; Decitabine; Deoxycytidine; Deoxycytidine Kinase; Equilibrative Nucleoside Transporter 1; Etoposide; Gemcitabine; HCT116 Cells; Humans; Irinotecan; Phosphorylation | 2017 |
Low doses of decitabine improve the chemotherapy efficacy against basal-like bladder cancer by targeting cancer stem cells.
Topics: Animals; Antimetabolites, Antineoplastic; Cisplatin; Decitabine; Deoxycytidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Gemcitabine; Humans; Male; Mice; Neoplastic Stem Cells; Urinary Bladder Neoplasms | 2019 |
Temozolomide, Gemcitabine, and Decitabine Hybrid Nanoconjugates: From Design to Proof-of-Concept (PoC) of Synergies toward the Understanding of Drug Impact on Human Glioblastoma Cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Decitabine; Deoxycytidine; Drug Delivery Systems; Drug Liberation; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Glioblastoma; Gold; Humans; Magnetic Resonance Spectroscopy; Metal Nanoparticles; Nanoconjugates; Proof of Concept Study; Spectrophotometry, Ultraviolet; Temozolomide | 2020 |