Compounds > gemcitabine
Page last updated: 2024-08-24

gemcitabine and cytochrome c-t

gemcitabine has been researched along with cytochrome c-t in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (37.50)29.6817
2010's10 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christgen, M; Haye, S; Kalthoff, H; Kremer, B; Kurdow, R; Schniewind, B; Ungefroren, H1
Ashley, SW; Benoit, E; Duxbury, MS; Ito, H; Waseem, T; Whang, EE1
Alsina, M; Beam, C; Beaupre, DM; Dalton, W; Gerbino, E; Hamilton, AD; Kerr, WG; Lichtenheld, MG; Mackley, PA; Muro-Cacho, C; Sebti, SM; Zhu, K1
Braconi, C; Henson, R; Lang, M; Patel, T1
Banerjee, S; Kong, D; Sarkar, FH; Wang, Z1
Banerjee, S; Kaseb, AO; Kong, D; Mohammad, M; Mohammad, RM; Padhye, S; Sarkar, FH; Wang, Z1
Sun, Q; Yu, J; Zhang, L; Zheng, X1
Chen, H; Guo, Y; Lin, S; Liu, A; Liu, J; Tan, W; Tong, H; Wang, Z; Wei, W1
Chen, H; Guo, H; Guo, Y; Lin, S; Liu, D; Wei, W1
Arnoletti, JP; Chen, Y; Jhala, NC; Jing, G; McDonald, JM; Turk, AN; Yuan, K; Zhang, K1
Chen, CY; Huang, AM; Li, JH; Liu, CH1
Cui, K; Li, L; Li, S; Niu, ZX; Sun, ZQ; Tian, H; Wang, AL; Wang, CL; Xue, Y; Zhang, B; Zhao, B; Zhou, WY1
Beckham, TH; Beeson, CC; Beeson, G; Bielawska, A; Bielawski, J; Cheng, JC; Drake, RR; Jones, EE; Lewis, CS; Liu, X; Lu, P; Marrison, T; Norris, JS; Ogretmen, B; Ramshesh, VK; Szulc, ZM1
Bao, GQ; Pan, CP; Peng, CH; Shen, BY; Shi, MM; Zhang, YJ1
Chen, MC; Eibl, G; Hines, OJ; Ishiguro, H; Matsuo, Y; Pham, H; Reber, HA; Takahashi, H; Takeyama, H1
Bu, HQ; Huang, H; Jin, HM; Li, Y; Liu, DL; Zhao, JF1

Other Studies

16 other study(ies) available for gemcitabine and cytochrome c-t

ArticleYear
Resistance of pancreatic cancer to gemcitabine treatment is dependent on mitochondria-mediated apoptosis.
    International journal of cancer, 2004, Mar-20, Volume: 109, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; BH3 Interacting Domain Death Agonist Protein; Carrier Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Caspase 9; Caspases; Cytochromes c; Deoxycytidine; Drug Resistance, Neoplasm; fas Receptor; Female; Gemcitabine; Intracellular Signaling Peptides and Proteins; Membrane Potentials; Mice; Mice, Inbred BALB C; Mice, SCID; Mitochondria; Pancreatic Neoplasms; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Retroviridae; Tumor Cells, Cultured

2004
A novel role for carcinoembryonic antigen-related cell adhesion molecule 6 as a determinant of gemcitabine chemoresistance in pancreatic adenocarcinoma cells.
    Cancer research, 2004, Jun-01, Volume: 64, Issue:11

    Topics: Adenocarcinoma; Antigens, CD; Antigens, Neoplasm; Antimetabolites, Antineoplastic; Caspase 3; Caspases; Cell Adhesion Molecules; Cell Line, Tumor; CSK Tyrosine-Protein Kinase; Cytochromes c; Deoxycytidine; Drug Resistance, Viral; Enzyme Activation; Gemcitabine; Gene Silencing; GPI-Linked Proteins; Humans; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; src-Family Kinases; Transfection

2004
Farnesyltransferase inhibitor R115777 (Zarnestra, Tipifarnib) synergizes with paclitaxel to induce apoptosis and mitotic arrest and to inhibit tumor growth of multiple myeloma cells.
    Blood, 2005, Jun-15, Volume: 105, Issue:12

    Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Bone Marrow Cells; Caspase 3; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Proliferation; Cisplatin; Clinical Trials as Topic; Cytochromes c; Deoxycytidine; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Synergism; Enzyme Activation; Farnesyltranstransferase; Flow Cytometry; Fluorouracil; G2 Phase; Gemcitabine; Homozygote; Humans; In Situ Nick-End Labeling; Inhibitory Concentration 50; Mice; Mice, SCID; Mitosis; Multiple Myeloma; Paclitaxel; Quinolones; Taxoids; Tetrazolium Salts; Thiazoles

2005
Epigallocatechin-gallate modulates chemotherapy-induced apoptosis in human cholangiocarcinoma cells.
    Liver international : official journal of the International Association for the Study of the Liver, 2009, Volume: 29, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Bile Duct Neoplasms; Blotting, Western; Camellia sinensis; Catechin; Cell Line, Tumor; Cholangiocarcinoma; Cytochromes c; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Immunohistochemistry; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitomycin; Plant Extracts

2009
3,3'-Diindolylmethane enhances chemosensitivity of multiple chemotherapeutic agents in pancreatic cancer.
    Cancer research, 2009, Jul-01, Volume: 69, Issue:13

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Cisplatin; Cytochromes c; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Indoles; NF-kappa B; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms

2009
Antitumor activity of gemcitabine and oxaliplatin is augmented by thymoquinone in pancreatic cancer.
    Cancer research, 2009, Jul-01, Volume: 69, Issue:13

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzoquinones; Caspases; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Survival; Cytochromes c; Deoxycytidine; Dinoprostone; Drug Synergism; Female; Gemcitabine; Humans; Mice; Mice, Inbred ICR; Mice, SCID; NF-kappa B; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms

2009
Smac modulates chemosensitivity in head and neck cancer cells through the mitochondrial apoptotic pathway.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, Apr-15, Volume: 17, Issue:8

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Apoptosis Regulatory Proteins; Biomimetic Materials; Blotting, Western; Caspase 3; Cell Line, Tumor; Cytochromes c; Deoxycytidine; Drug Synergism; Enzyme Activation; Female; Gemcitabine; Head and Neck Neoplasms; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Nude; Mitochondria; Mitochondrial Proteins; RNA Interference; Signal Transduction; Xenograft Model Antitumor Assays

2011
Enhanced effect of gemcitabine by emodin against pancreatic cancer in vivo via cytochrome C-regulated apoptosis.
    Oncology reports, 2011, Volume: 25, Issue:5

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Deoxycytidine; Drug Synergism; Emodin; Female; Gemcitabine; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Xenograft Model Antitumor Assays

2011
[Emodin enhances antitumor effect of gemcitabine in model of SW1990 cell xenograft on athymic mouse].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2010, Volume: 35, Issue:24

    Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytochromes c; Deoxycytidine; Drug Synergism; Emodin; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Proto-Oncogene Proteins c-bcl-2; Tumor Burden; Xenograft Model Antitumor Assays

2010
Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis.
    Laboratory investigation; a journal of technical methods and pathology, 2011, Volume: 91, Issue:6

    Topics: Animals; Apoptosis; Blotting, Western; Caspases; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; Cytochromes c; Deoxycytidine; Drug Therapy, Combination; Enzyme Activation; Gemcitabine; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Nude; Tamoxifen

2011
Subamolide A, a component isolated from Cinnamomum subavenium, induces apoptosis mediated by mitochondria-dependent, p53 and ERK1/2 pathways in human urothelial carcinoma cell line NTUB1.
    Journal of ethnopharmacology, 2011, Sep-01, Volume: 137, Issue:1

    Topics: 4-Butyrolactone; Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Carcinoma; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Cinnamomum; Cisplatin; Cytochromes c; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Flow Cytometry; Gemcitabine; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Plant Preparations; Plant Stems; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Signal Transduction; Time Factors; Tumor Suppressor Protein p53; Urologic Neoplasms; Urothelium

2011
Mechanisms of TRAIL and gemcitabine induction of pancreatic cancer cell apoptosis.
    Asian Pacific journal of cancer prevention : APJCP, 2011, Volume: 12, Issue:10

    Topics: Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Deoxycytidine; Down-Regulation; Gemcitabine; Humans; Intracellular Signaling Peptides and Proteins; Mitochondrial Proteins; Pancreatic Neoplasms; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation; X-Linked Inhibitor of Apoptosis Protein

2011
LCL124, a cationic analog of ceramide, selectively induces pancreatic cancer cell death by accumulating in mitochondria.
    The Journal of pharmacology and experimental therapeutics, 2013, Volume: 344, Issue:1

    Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Benzimidazoles; Blotting, Western; Carbocyanines; Cell Death; Cell Line, Tumor; Ceramides; Chromatography, High Pressure Liquid; Coloring Agents; Cytochromes c; Deoxycytidine; Female; Gemcitabine; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Oxygen Consumption; Pancreatic Neoplasms; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrum Analysis; Xenograft Model Antitumor Assays

2013
Andrographolide causes apoptosis via inactivation of STAT3 and Akt and potentiates antitumor activity of gemcitabine in pancreatic cancer.
    Toxicology letters, 2013, Sep-12, Volume: 222, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Apoptosis; Blotting, Western; Cell Count; Cell Cycle; Cell Line, Tumor; Coloring Agents; Cytochromes c; Deoxycytidine; Diterpenes; Drug Synergism; Flow Cytometry; Gemcitabine; Gentian Violet; Humans; Ki-67 Antigen; Male; Mice; Mice, Inbred BALB C; Pancreatic Neoplasms; Proto-Oncogene Proteins c-akt; STAT3 Transcription Factor; Xenograft Model Antitumor Assays

2013
Simultaneous knock-down of Bcl-xL and Mcl-1 induces apoptosis through Bax activation in pancreatic cancer cells.
    Biochimica et biophysica acta, 2013, Volume: 1833, Issue:12

    Topics: Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Caspases; Cell Line, Tumor; Cytochromes c; Deoxycytidine; Enzyme Activation; Gemcitabine; Gene Knockdown Techniques; Humans; Mitochondria; Myeloid Cell Leukemia Sequence 1 Protein; Pancreatic Neoplasms

2013
Enhancement of the effects of gemcitabine against pancreatic cancer by oridonin via the mitochondrial caspase-dependent signaling pathway.
    Molecular medicine reports, 2014, Volume: 10, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Deoxycytidine; Diterpenes, Kaurane; Drug Synergism; G1 Phase Cell Cycle Checkpoints; Gemcitabine; Humans; Mitochondria; Pancreatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Signal Transduction

2014