Page last updated: 2024-08-24

gemcitabine and cytidine monophosphate

gemcitabine has been researched along with cytidine monophosphate in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's2 (28.57)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Bao, H; Furman, PA; McBrayer, TR; Micolochick Steuer, HM; Murakami, E; Obikhod, A; Otto, MJ; Ramesh, M; Schinazi, RF; Stuyver, LJ; Whitaker, T1
Tsukagoshi, S1
Borch, RF; Peters, GJ; Sigmond, J; Wu, W1
Balzarini, J; Blagden, S; Ghazaly, E; Jiang, WG; Lopez, MH; Mason, M; McGuigan, C; Slusarczyk, M; Thompson, E1
Bré, J; Chan, TH; Harrison, DJ; Mullen, P; Reynolds, PA; Sarr, A; Um, IH1
Abdelrahman, A; Arora, M; Barrett, MT; Bogenberger, JM; Borad, MJ; Braggio, E; Chen, X; Egan, JB; Kasimsetty, A; Kosiorek, HE; Leiting, JL; Lenkiewicz, E; Malasi, S; Nagalo, BM; Salomao, MA; Truty, MJ; Uson, PLS; Zhou, Y1
Blagden, SP; Kapacee, ZA; Knox, JJ; Lamarca, A; McNamara, MG; Palmer, D; Valle, JW1

Reviews

2 review(s) available for gemcitabine and cytidine monophosphate

ArticleYear
[Recent development of antitumor antimetabolites in Japan--cytosine arabinoside analogues].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:7

    Topics: Animals; Antimetabolites, Antineoplastic; Arabinonucleotides; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Cytarabine; Cytidine Monophosphate; Deoxycytidine; Gemcitabine; Humans; Lung Neoplasms; Mice; Neoplasm Transplantation

1997
NUC-1031, use of ProTide technology to circumvent gemcitabine resistance: current status in clinical trials.
    Medical oncology (Northwood, London, England), 2020, Jun-11, Volume: 37, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Cisplatin; Clinical Trials as Topic; Cytidine Monophosphate; Deoxycytidine; Drug Resistance, Neoplasm; Drug Synergism; Female; Gemcitabine; Humans; Ovarian Neoplasms; Pancreatic Neoplasms; Randomized Controlled Trials as Topic; Treatment Outcome

2020

Other Studies

5 other study(ies) available for gemcitabine and cytidine monophosphate

ArticleYear
Mechanism of activation of beta-D-2'-deoxy-2'-fluoro-2'-c-methylcytidine and inhibition of hepatitis C virus NS5B RNA polymerase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:2

    Topics: Antiviral Agents; Catalysis; Deoxycytidine; Hepacivirus; Hepatitis C; Humans; Mutation; Phosphorylation; RNA-Dependent RNA Polymerase; RNA, Viral; Structure-Activity Relationship; Viral Nonstructural Proteins; Virus Replication

2007
Synthesis and biological activity of a gemcitabine phosphoramidate prodrug.
    Journal of medicinal chemistry, 2007, Jul-26, Volume: 50, Issue:15

    Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytidine Monophosphate; Deoxycytidine; Deoxycytidine Kinase; Dipyridamole; Drug Screening Assays, Antitumor; Gemcitabine; Humans; Nucleoside Transport Proteins; Prodrugs; Structure-Activity Relationship

2007
Application of ProTide technology to gemcitabine: a successful approach to overcome the key cancer resistance mechanisms leads to a new agent (NUC-1031) in clinical development.
    Journal of medicinal chemistry, 2014, Feb-27, Volume: 57, Issue:4

    Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; Cytidine Monophosphate; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans

2014
Genome-scale CRISPR/Cas9 screen determines factors modulating sensitivity to ProTide NUC-1031.
    Scientific reports, 2019, 05-21, Volume: 9, Issue:1

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Clinical Trials, Phase I as Topic; CRISPR-Cas Systems; Cytidine Monophosphate; Deoxycytidine; Deoxycytidine Kinase; Drug Resistance, Neoplasm; Female; Gemcitabine; HEK293 Cells; Humans; Ovarian Neoplasms; Pancreatic Neoplasms

2019
Evaluation of NUC-1031: a first-in-class ProTide in biliary tract cancer.
    Cancer chemotherapy and pharmacology, 2020, Volume: 85, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biliary Tract Neoplasms; Cell Proliferation; Cisplatin; Cytidine Monophosphate; Deoxycytidine; Drug Synergism; Female; Gemcitabine; Humans; Mice; Mice, Inbred NOD; Mice, SCID; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2020