gemcitabine has been researched along with curcumin in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (20.59) | 29.6817 |
| 2010's | 20 (58.82) | 24.3611 |
| 2020's | 7 (20.59) | 2.80 |
| Authors | Studies |
|---|---|
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Aggarwal, BB; Kamat, AM; Sethi, G | 1 |
| Aggarwal, BB; Diagaradjane, P; Gelovani, J; Guha, S; Krishnan, S; Kunnumakkara, AB | 1 |
| Aderka, D; Ashkenazy-Voghera, M; Ben-Yosef, R; Greif, J; Lev-Ari, S; Starr, A; Vexler, A | 1 |
| Dixon, J; Holcomb, B; Kennard, J; Mahomed, J; Matos, JM; Schmidt, CM; Sebolt-Leopold, J; Shanmugam, R; Yip-Schneider, MT | 1 |
| Saif, MW | 1 |
| Buchsbaum, DJ; Grizzle, WE; Li, J; Oelschlager, DK; Tian, DA; Wan, M; Wang, P; Wang, Y; Yang, C; Zheng, Y | 1 |
| Aggarwal, BB; Inamoto, T; Kamat, AM; Sung, B; Tharakan, ST | 1 |
| Majumdar, AP; Patel, BB | 1 |
| Ahmad, A; Ali, S; Banerjee, S; Dominiak, K; Padhye, S; Philip, PA; Sarkar, FH; Schaffert, JM; Wang, Z | 1 |
| Aviram, A; Escalon, E; Melnick, SJ; Ramachandran, C; Resek, AP | 1 |
| Brand, RE; Singh, SV; Stan, SD | 1 |
| Bisht, S; Chenna, V; Feldmann, G; Goggins, MG; Hong, SM; Karikari, C; Maitra, A; Mizuma, M; Ottenhof, NA; Pramanik, D; Ravi, R; Rudek, MA; Sharma, R | 1 |
| Aggarwal, BB; Asada, M; Chiba, T; Guha, S; Imaizumi, A; Kanai, M; Kawaguchi, Y; Masui, T; Matsumoto, S; Mori, Y; Nishimura, T; Suzuki, C; Yanagihara, K; Yazumi, S; Yoshimura, K | 1 |
| Badmaev, V; Bar-Sela, G; Epelbaum, R; Schaffer, M; Vizel, B | 1 |
| Aboukameel, A; Ali, S; Banerjee, S; Bao, B; Kong, D; Padhye, S; Philip, PA; Sarkar, FH; Sarkar, SH; Wang, Z | 1 |
| Bekaert, S; Cataldo, D; Chiap, P; Coia, I; Evrard, B; Foidart, JM; Gueders, M; Noel, A; Paulissen, G; Rocks, N; Van Heugen, JC | 1 |
| Arra, C; Barbieri, A; Bimonte, S; Luciano, A; Palma, G; Rea, D | 1 |
| Li, Y; Lim, J; Paxton, J; Wu, Z; Xu, H | 1 |
| Uwagawa, T; Yanaga, K | 1 |
| Fuchs, JR; He, F; Highfill, CA; Ji, M; Li, K; Li, L; Lian, J; Lin, J; Marquez, RT; Tang, W; Wu, X; Xu, L | 1 |
| An, Y; Duan, J; Fan, S; Li, X; Pan, Y; Tie, L; Wang, X; Xiaokaiti, Y; Yang, H; Ye, M | 1 |
| Avan, A; Fayazbakhsh, H; Hassanian, SM; Hosseini, M; Khazaei, M; Maftouh, M; Mohammadzadeh, E; ShahidSales, S | 1 |
| Marasini, B; Sahu, RP | 1 |
| Bugde, P; Hawkins, BC; Li, Y; Paxton, JW; Revalde, JL; Rosengren, RJ; Wijeratne, TS | 1 |
| Goel, A; Han, H; Ravindranathan, P; Toden, S; Yoshida, K | 1 |
| Bardini, R; Buda, A; D'Ippolito, S; Da Dalt, G; Fabricio, ASC; Fiduccia, P; Gion, M; Giovanis, P; Pastorelli, D; Rainato, G; Soldà, C; Sperti, C; Ursini, F | 1 |
| Alabkaa, A; Behrman, S; Chauhan, SC; Dan, N; Ganju, A; Hafeez, BB; Jaggi, M; Khan, S; Kumari, S; Massey, A; Setua, S; Stiles, ZE; Yallapu, MM; Yue, J | 1 |
| Debnath, MC; Ganguly, S; Kazi, J; Mukhopadhyay, R; Paul, B; Sen, R | 1 |
| Bu, LP; Li, XY; Liu, H; Liu, P; Shao, L; Ying, Q; Yu, SQ | 1 |
| Ding, J; Gao, L; Shao, T; Zheng, W | 1 |
| Li, Y; Paxton, JW; Wu, Z; Xu, H | 1 |
| Dong, Z; Feng, Q; Gong, J; Liu, Q; Zhang, H | 1 |
| Chen, JY; Jiang, JL; Ma, T; Qi, WX; Xu, HP | 1 |
5 review(s) available for gemcitabine and curcumin
| Article | Year |
|---|---|
Synergistic role of curcumin with current therapeutics in colorectal cancer: minireview.
Topics: Adenoma; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Colorectal Neoplasms; Curcumin; Deoxycytidine; Fluorouracil; Gastrointestinal Neoplasms; Gemcitabine; Humans; Organoplatinum Compounds; Oxaliplatin; Treatment Outcome | 2009 |
Chemoprevention strategies for pancreatic cancer.
Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; beta Carotene; Camellia sinensis; Celecoxib; Cell Transformation, Neoplastic; Chemoprevention; Curcumin; Cyclooxygenase 2 Inhibitors; Deoxycytidine; Disease Models, Animal; Down-Regulation; Drug Synergism; Gemcitabine; Humans; Isothiocyanates; Pancreatic Neoplasms; Phototherapy; Pyrazoles; Sulfonamides; Tea; Vitamin D; Vitamin E | 2010 |
Effect of NF-κB inhibition on chemoresistance in biliary-pancreatic cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Benzamidines; Biliary Tract Neoplasms; Bortezomib; Camptothecin; Curcumin; Deoxycytidine; Ditiocarb; Drug Resistance, Neoplasm; Gemcitabine; Guanidines; Humans; Irinotecan; Molecular Targeted Therapy; NF-kappa B; Paclitaxel; Pancreatic Neoplasms; Pregnenediones; Treatment Outcome | 2015 |
Therapeutic Potential of Curcumin in Treatment of Pancreatic Cancer: Current Status and Future Perspectives.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Curcumin; Deoxycytidine; Gemcitabine; Humans; Pancreatic Neoplasms | 2017 |
Natural Anti-Cancer Agents: Implications in Gemcitabine-Resistant Pancreatic Cancer Treatment.
Topics: Antineoplastic Agents; Biological Products; Combined Modality Therapy; Curcumin; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Pancreatic Neoplasms | 2017 |
3 trial(s) available for gemcitabine and curcumin
| Article | Year |
|---|---|
A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Curcumin; Deoxycytidine; Drug Combinations; Drug Resistance, Neoplasm; Drug Synergism; Female; Gemcitabine; Humans; Male; Medication Adherence; Middle Aged; Oxonic Acid; Pancreatic Neoplasms; Survival Rate; Tegafur | 2011 |
Curcumin and gemcitabine in patients with advanced pancreatic cancer.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Curcumin; Deoxycytidine; Disease Progression; Feasibility Studies; Female; Gemcitabine; Humans; Male; Medication Adherence; Middle Aged; Pancreatic Neoplasms; Severity of Illness Index; Survival Analysis | 2010 |
Phytosome complex of curcumin as complementary therapy of advanced pancreatic cancer improves safety and efficacy of gemcitabine: Results of a prospective phase II trial.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Complementary Therapies; Curcumin; Deoxycytidine; Female; Gemcitabine; Humans; Male; Middle Aged; Pancreatic Neoplasms; Phospholipids; Treatment Outcome | 2018 |
26 other study(ies) available for gemcitabine and curcumin
| Article | Year |
|---|---|
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Curcumin potentiates the apoptotic effects of chemotherapeutic agents and cytokines through down-regulation of nuclear factor-kappaB and nuclear factor-kappaB-regulated gene products in IFN-alpha-sensitive and IFN-alpha-resistant human bladder cancer cell
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Curcumin; Cyclooxygenase 2; Deoxycytidine; Down-Regulation; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Humans; Interferon-alpha; Membrane Proteins; NF-kappa B; Paclitaxel; Poly(ADP-ribose) Polymerases; Smoking; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A | 2007 |
Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-kappaB-regulated gene products.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Growth Processes; Cell Line, Tumor; Curcumin; Cyclooxygenase 2; Deoxycytidine; Down-Regulation; Drug Synergism; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinase 9; Mice; Neovascularization, Pathologic; NF-kappa B; Pancreatic Neoplasms; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays | 2007 |
Curcumin augments gemcitabine cytotoxic effect on pancreatic adenocarcinoma cell lines.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Survival; Curcumin; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pancreatic Neoplasms | 2007 |
Pancreatic cancer cell genetics and signaling response to treatment correlate with efficacy of gemcitabine-based molecular targeting strategies.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Blotting, Western; Cell Proliferation; Chromones; Curcumin; Deoxycytidine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Gemcitabine; Humans; MAP Kinase Signaling System; Morpholines; NF-kappa B; Pancreatic Neoplasms; Proto-Oncogene Proteins c-akt; Tumor Cells, Cultured | 2008 |
Is there a role for herbal medicine in the treatment of pancreatic cancer?. Highlights from the "44th ASCO Annual Meeting". Chicago, IL, USA. May 30 - June 3, 2008.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Curcumin; Deoxycytidine; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Fluorouracil; Gemcitabine; Herbal Medicine; Humans; Multicenter Studies as Topic; Pancreatic Neoplasms; Plant Preparations | 2008 |
Polyethylene glycosylated curcumin conjugate inhibits pancreatic cancer cell growth through inactivation of Jab1.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; COP9 Signalosome Complex; Curcumin; Deoxycytidine; Gemcitabine; Humans; Intracellular Signaling Peptides and Proteins; Male; Pancreatic Neoplasms; Peptide Hydrolases; Polyethylene Glycols | 2009 |
Curcumin potentiates the antitumor effects of gemcitabine in an orthotopic model of human bladder cancer through suppression of proliferative and angiogenic biomarkers.
Topics: Antimetabolites, Antineoplastic; Base Sequence; Cell Line, Tumor; Cell Proliferation; Curcumin; Deoxycytidine; DNA Primers; Drug Synergism; Gemcitabine; Humans; Models, Biological; Neovascularization, Pathologic; Urinary Bladder Neoplasms | 2010 |
Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Curcumin; Deoxycytidine; Dinoprostone; DNA, Complementary; DNA, Neoplasm; Drug Synergism; Gemcitabine; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; MicroRNAs; NF-kappa B; Oligonucleotides, Antisense; Pancreatic Neoplasms; PTEN Phosphohydrolase; Transfection; Triterpenes; Vascular Endothelial Growth Factor A | 2010 |
Potentiation of gemcitabine by Turmeric Force in pancreatic cancer cell lines.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Curcumin; Cyclooxygenase 2; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Immunoblotting; Interleukin-8; NF-kappa B; Pancreatic Neoplasms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; STAT3 Transcription Factor | 2010 |
Systemic administration of polymeric nanoparticle-encapsulated curcumin (NanoCurc) blocks tumor growth and metastases in preclinical models of pancreatic cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Availability; Cell Line, Tumor; Cell Proliferation; Curcumin; Cyclin D1; Deoxycytidine; Disease Models, Animal; Down-Regulation; Drug Synergism; Gemcitabine; Humans; Matrix Metalloproteinase 9; Mice; Nanoparticles; Neoplasm Metastasis; NF-kappa B; Pancreatic Neoplasms; Polymers; Subcutaneous Tissue; Xenograft Model Antitumor Assays | 2010 |
Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer.
Topics: Animals; Antigens, Neoplasm; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Adhesion Molecules; Cell Aggregation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Clone Cells; Curcumin; Deoxycytidine; Drug Resistance, Neoplasm; Epithelial Cell Adhesion Molecule; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Mice; MicroRNAs; Neoplasm Invasiveness; Neoplasm Proteins; NF-kappa B; Pancreatic Neoplasms; PTEN Phosphohydrolase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2011 |
Curcumin-cyclodextrin complexes potentiate gemcitabine effects in an orthotopic mouse model of lung cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Proliferation; Curcumin; Cyclodextrins; Deoxycytidine; Drug Synergism; G2 Phase; Gemcitabine; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Tumor Cells, Cultured | 2012 |
Curcumin inhibits tumor growth and angiogenesis in an orthotopic mouse model of human pancreatic cancer.
Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Curcumin; Deoxycytidine; Disease Models, Animal; Gemcitabine; Humans; Mice; Mice, Nude; Neovascularization, Pathologic; NF-kappa B; Pancreatic Neoplasms | 2013 |
Development of a gradient high performance liquid chromatography assay for simultaneous analysis of hydrophilic gemcitabine and lipophilic curcumin using a central composite design and its application in liposome development.
Topics: Biological Assay; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Curcumin; Deoxycytidine; Gemcitabine; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Limit of Detection; Liposomes | 2014 |
Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Chemoradiotherapy; Curcumin; Deoxycytidine; Drug Resistance, Neoplasm; Drug Synergism; Female; Gemcitabine; Humans; Mice; Mice, Nude; Pancreatic Neoplasms; Radiation Tolerance; Random Allocation; Signal Transduction; STAT3 Transcription Factor; Survival Analysis | 2016 |
Bisdemethoxycurcumin exerts pro-apoptotic effects in human pancreatic adenocarcinoma cells through mitochondrial dysfunction and a GRP78-dependent pathway.
Topics: Adenocarcinoma; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Curcumin; Deoxycytidine; Diarylheptanoids; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Endoplasmic Reticulum Chaperone BiP; Eukaryotic Initiation Factor-2; Gemcitabine; Heat-Shock Proteins; Humans; Mitochondria; Pancreatic Neoplasms; Prohibitins; Protein Deglycase DJ-1; Protein Interaction Maps; Repressor Proteins; RNA Interference; Signal Transduction; Transcription Factor CHOP; Transfection | 2016 |
Curcumin and its cyclohexanone analogue inhibited human Equilibrative nucleoside transporter 1 (ENT1) in pancreatic cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Curcumin; Cyclohexanones; Deoxycytidine; Drug Interactions; Drug Resistance, Neoplasm; Equilibrative Nucleoside Transporter 1; Gemcitabine; Humans; Pancreatic Neoplasms; Uridine | 2017 |
Curcumin sensitizes pancreatic cancer cells to gemcitabine by attenuating PRC2 subunit EZH2, and the lncRNA PVT1 expression.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Cycle Checkpoints; Cell Line, Tumor; Curcumin; Deoxycytidine; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice, Nude; Neoplastic Stem Cells; Pancreatic Neoplasms; RNA, Long Noncoding; Xenograft Model Antitumor Assays | 2017 |
Superparamagnetic iron oxide nanoparticles of curcumin enhance gemcitabine therapeutic response in pancreatic cancer.
Topics: Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Chemokine CXCL12; Curcumin; Deoxycytidine; Enzyme-Linked Immunosorbent Assay; Ferric Compounds; Gemcitabine; Humans; Magnetite Nanoparticles; Mice; Microscopy, Confocal; Nanoparticles; Pancreatic Neoplasms; Receptors, CXCR4 | 2019 |
Gemcitabine Co-Encapsulated with Curcumin in Folate Decorated PLGA Nanoparticles; a Novel Approach to Treat Breast Adenocarcinoma.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Curcumin; Deoxycytidine; Drug Carriers; Drug Delivery Systems; Female; Folic Acid; Gemcitabine; Humans; Mice, Nude; Nanoparticles; Polylactic Acid-Polyglycolic Acid Copolymer | 2020 |
Curcumin enhances anti‑cancer efficacy of either gemcitabine or docetaxel on pancreatic cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cadherins; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcuma; Curcumin; Deoxycytidine; Docetaxel; Drug Synergism; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pancreatic Neoplasms; Plant Extracts; Poly (ADP-Ribose) Polymerase-1; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2 | 2020 |
Curcumin suppresses tumor growth of gemcitabine-resistant non-small cell lung cancer by regulating lncRNA-MEG3 and PTEN signaling.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Curcumin; Deoxycytidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Lung Neoplasms; PTEN Phosphohydrolase; RNA, Long Noncoding; Signal Transduction; Tumor Cells, Cultured | 2021 |
Co-Delivery Using pH-Sensitive Liposomes to Pancreatic Cancer Cells: the Effects of Curcumin on Cellular Concentration and Pharmacokinetics of Gemcitabine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Curcumin; Deoxycytidine; Drug Liberation; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Humans; Hydrogen-Ion Concentration; Liposomes; Male; Multidrug Resistance-Associated Proteins; Pancreatic Neoplasms; Polyethylene Glycols; Rats | 2021 |
Curcumin enhances drug sensitivity of gemcitabine-resistant lung cancer cells and inhibits metastasis.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Curcumin; Deoxycytidine; Gemcitabine; Lung Neoplasms; Mice; Mice, Nude | 2021 |
A Novel Delivery System of RGD-HSA Loaded GEM/CUR Nanoparticles for the Treatment of Pancreatic Cancer Therapy.
Topics: Animals; Cell Line, Tumor; Curcumin; Deoxycytidine; Drug Carriers; Gemcitabine; Humans; Mice; Nanoparticles; Oligopeptides; Pancreatic Neoplasms; Particle Size; Serum Albumin, Human | 2022 |