Compounds > gemcitabine
Page last updated: 2024-08-24

gemcitabine and birinapant

gemcitabine has been researched along with birinapant in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (71.43)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Jusko, WJ; Straubinger, RM; Zhu, X1
Green, JE; He, S; Min, DJ1
Kirouac, DC1
Jusko, WJ; Straubinger, RM; Trueman, S; Zhu, X1
Jusko, WJ; Qu, J; Shen, X; Straubinger, RM; Zhu, X1
Bartholomeusz, C; Devi, GR; Lee, J; Liu, H; Lu, AY; Pearson, T; Tripathy, D; Ueno, NT; Xie, X1

Other Studies

7 other study(ies) available for gemcitabine and birinapant

ArticleYear
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Mechanism-based mathematical modeling of combined gemcitabine and birinapant in pancreatic cancer cells.
    Journal of pharmacokinetics and pharmacodynamics, 2015, Volume: 42, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Cycle; Cell Line, Tumor; Deoxycytidine; Dipeptides; Gemcitabine; Humans; Indoles; Models, Theoretical; Pancreatic Neoplasms

2015
Birinapant (TL32711) Improves Responses to GEM/AZD7762 Combination Therapy in Triple-negative Breast Cancer Cell Lines.
    Anticancer research, 2016, Volume: 36, Issue:6

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Checkpoint Kinase 1; Deoxycytidine; Dipeptides; DNA Repair; Female; Gemcitabine; Humans; Indoles; Phosphorylation; Thiophenes; Triple Negative Breast Neoplasms; Urea

2016
How Do We "Validate" a QSP Model?
    CPT: pharmacometrics & systems pharmacology, 2018, Volume: 7, Issue:9

    Topics: Deoxycytidine; Dipeptides; Gemcitabine; Humans; Indoles; Pancreatic Neoplasms; Proteomics

2018
Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts.
    Journal of pharmacokinetics and pharmacodynamics, 2018, Volume: 45, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Deoxycytidine; Dipeptides; Female; Gemcitabine; Heterografts; Humans; Indoles; Male; Mice; Mice, Nude; Middle Aged; Models, Biological; Pancreatic Neoplasms; Tumor Burden; Xenograft Model Antitumor Assays

2018
Multi-Scale Network Model Supported by Proteomics for Analysis of Combined Gemcitabine and Birinapant Effects in Pancreatic Cancer Cells.
    CPT: pharmacometrics & systems pharmacology, 2018, Volume: 7, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Dipeptides; Gemcitabine; Humans; Indoles; Models, Biological; Pancreatic Neoplasms; Proteomics; Signal Transduction

2018
Birinapant Enhances Gemcitabine's Antitumor Efficacy in Triple-Negative Breast Cancer by Inducing Intrinsic Pathway-Dependent Apoptosis.
    Molecular cancer therapeutics, 2021, Volume: 20, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Deoxycytidine; Dipeptides; Enzyme Inhibitors; Female; Gemcitabine; Humans; Indoles; Mice; Mice, Nude; Triple Negative Breast Neoplasms

2021