gemcitabine has been researched along with ascorbic acid in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 15 (93.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dinney, CP; Highshaw, R; Kamat, AM; Kassouf, W; Nelkin, GM | 1 |
| Chalmers, B; Chen, P; Chen, Q; Drisko, J; Espey, MG; Levine, M; Sun, AY | 1 |
| Buettner, GR; Cullen, JJ; Spitz, DR | 1 |
| Burlando, B; Martinotti, S; Ranzato, E | 1 |
| Bazzan, AJ; Deshmukh, S; Levine, M; Littman, S; Mitchell, E; Monti, DA; Newberg, AB; Pillai, MV; Yeo, CJ; Zabrecky, G | 1 |
| Berg, DJ; Bodeker, KL; Buettner, GR; Cullen, JJ; Drisko, J; Du, J; Halfdanarson, TR; Levine, M; Roberts, LJ; van't Erve, TJ; Wagner, BA; Welsh, JL; Yee, NS; Zehr, PS | 1 |
| Biffo, S; Burlando, B; Gallo, S; Martinotti, S; Mutti, L; Ranzato, E; Russo, MV; Volta, V | 1 |
| Burlando, B; Martinotti, S; Parodi, M; Ranzato, E; Vitale, M | 1 |
| Antunes Soares, FA; Araújo, Mdo C; Baldissareli, J; Belmonte Pereira, L; Bitencourt Rosa Leal, D; Brenner Reetz, LG; Chiesa, J; Curry Martins, C; Morsch, VM; Pelinson, LP; Pires Amaral, G; Schetinger, MR; Schmatz, R; Zanini, D | 1 |
| Buettner, GR; Button, A; Cieslak, JA; Cullen, JJ; Doskey, CM; Du, J; Rawal, M; Schroeder, SR; Strother, RK; Wagner, BA | 1 |
| Cieslak, JA; Cullen, JJ | 1 |
| Allen, BG; Bradley, MD; Buettner, GR; Mapuskar, KA; Milhem, M; Monga, V; Schoenfeld, JD; Sibenaller, ZA; Spitz, DR; Wagner, BA | 1 |
| Chen, P; Chen, Q; Dong, R; Drisko, JA; Fan, F; Godwin, AK; Levine, M; Pessetto, Z; Polireddy, K; Reed, G; Violet, PC; Williamson, S; Yu, J | 1 |
| Alexander, MS; Allen, BG; Berg, DJ; Bodeker, KL; Brown, HA; Buatti, JM; Buettner, GR; Cullen, JJ; Du, J; Gibson-Corley, K; O'Leary, BR; Schroeder, SR; Spitz, DR; Vollstedt, S; Wagner, BA; Wilkes, JG | 1 |
| Arteta, B; Benedicto, A; Hernandez-Unzueta, I; Herrero, A; Márquez, J; Olaso, E; Romayor, I; Sanz, E | 1 |
2 review(s) available for gemcitabine and ascorbic acid
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Treatment of Pancreatic Cancer with Pharmacological Ascorbate.
Topics: Animals; Antioxidants; Ascorbic Acid; Deoxycytidine; Gemcitabine; Humans; Hydrogen Peroxide; Oxidative Stress; Pancreatic Neoplasms | 2015 |
4 trial(s) available for gemcitabine and ascorbic acid
| Article | Year |
|---|---|
Phase I evaluation of intravenous ascorbic acid in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Deoxycytidine; Dose-Response Relationship, Drug; Drug Administration Schedule; Erlotinib Hydrochloride; Female; Gemcitabine; Humans; Infusions, Intravenous; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Pancreatic Neoplasms; Pulmonary Embolism; Quinazolines; Treatment Outcome | 2012 |
Pharmacological ascorbate with gemcitabine for the control of metastatic and node-positive pancreatic cancer (PACMAN): results from a phase I clinical trial.
Topics: Adenocarcinoma; Aged; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Ascorbic Acid; Chromatography, High Pressure Liquid; Deoxycytidine; Disease-Free Survival; Drug Administration Schedule; Female; Gemcitabine; Glutathione; Humans; Infusions, Intravenous; Male; Middle Aged; Pancreatic Neoplasms; Patient Compliance; Patient Safety; Sentinel Lymph Node Biopsy | 2013 |
High Dose Parenteral Ascorbate Inhibited Pancreatic Cancer Growth and Metastasis: Mechanisms and a Phase I/IIa study.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Ascorbic Acid; Cell Proliferation; Deoxycytidine; Female; Follow-Up Studies; Gemcitabine; Humans; Infusions, Parenteral; Mice; Mice, Nude; Neoplasm Metastasis; Pancreatic Neoplasms; Prognosis; Prospective Studies; Tissue Distribution; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |
Pharmacologic Ascorbate Reduces Radiation-Induced Normal Tissue Toxicity and Enhances Tumor Radiosensitization in Pancreatic Cancer.
Topics: Aged; Aged, 80 and over; Animals; Ascorbic Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Collagen; Deoxycytidine; Disease-Free Survival; DNA Damage; Female; Gemcitabine; Glutathione; Humans; Male; Mice; Mice, Nude; Middle Aged; Oxidative Stress; Pancreatic Neoplasms; Radiation Tolerance; Radiotherapy; Recombinant Proteins; Treatment Outcome | 2018 |
10 other study(ies) available for gemcitabine and ascorbic acid
| Article | Year |
|---|---|
Vitamins C and K3 sensitize human urothelial tumors to gemcitabine.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Ascorbic Acid; Carcinoma; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Gemcitabine; Humans; Male; Mice; Mice, Inbred BALB C; Urinary Bladder Neoplasms; Urothelium; Vitamin K 3; Vitamins | 2006 |
Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Carcinoma; Cell Line, Tumor; Deoxycytidine; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Female; Gemcitabine; Humans; Mice; Mice, Nude; Pancreatic Neoplasms; Xenograft Model Antitumor Assays | 2011 |
Comment on "Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer," i.e., all we are saying is, give C a chance.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Injections, Intravenous; Mice; Pancreatic Neoplasms; Treatment Outcome | 2011 |
In vitro screening of synergistic ascorbate-drug combinations for the treatment of malignant mesothelioma.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Catechin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Coloring Agents; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Mesothelioma; Neutral Red | 2011 |
Preclinical demonstration of synergistic Active Nutrients/Drug (AND) combination as a potential treatment for malignant pleural mesothelioma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Ascorbic Acid; Catechin; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Lung Neoplasms; Male; Mesothelioma; Mesothelioma, Malignant; Mice; Mice, Inbred NOD; Mice, SCID; Pleural Neoplasms; Signal Transduction; Xenograft Model Antitumor Assays | 2013 |
Combination of ascorbate/epigallocatechin-3-gallate/gemcitabine synergistically induces cell cycle deregulation and apoptosis in mesothelioma cells.
Topics: Apoptosis; Ascorbic Acid; Catechin; Cell Cycle; Cell Line, Tumor; Deoxycytidine; Drug Combinations; Drug Synergism; Gemcitabine; Humans; Mesothelioma | 2014 |
δ-Aminolevulinate dehydratase activity in lung cancer patients and its relationship with oxidative stress.
Topics: Aged; Ascorbic Acid; Blood Platelets; Case-Control Studies; Catalase; Cisplatin; Deoxycytidine; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Middle Aged; Oxidative Stress; Porphobilinogen Synthase; Reactive Oxygen Species; Sulfhydryl Compounds; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Vitamin E | 2014 |
Manganoporphyrins and ascorbate enhance gemcitabine cytotoxicity in pancreatic cancer.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Ascorbic Acid; Catalase; Catalysis; Deoxycytidine; Drug Synergism; Fluorescent Antibody Technique; Free Radical Scavengers; Gemcitabine; Histones; Humans; Hydrogen Peroxide; Metalloporphyrins; Mice; Mice, Nude; Oxidation-Reduction; Oxidative Stress; Oxygen Consumption; Pancreatic Neoplasms; Xenograft Model Antitumor Assays | 2015 |
Redox active metals and H
Topics: Animals; Antimetabolites, Antineoplastic; Ascorbic Acid; Cell Line, Tumor; Deoxycytidine; DNA Damage; Female; Gemcitabine; Humans; Hydrogen Peroxide; Iron; Mice, Nude; Oxidation-Reduction; Radiation-Sensitizing Agents; Sarcoma | 2018 |
Ocoxin Oral Solution Exerts an Antitumoral Effect in Pancreatic Cancer and Reduces the Stromal-Mediated Chemoresistance.
Topics: Adenocarcinoma; Administration, Oral; Animals; Antineoplastic Agents; Ascorbic Acid; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Survival; Deoxycytidine; Drug Resistance, Neoplasm; Folic Acid; Gemcitabine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Mice, Inbred C57BL; Neoplasms, Experimental; Paclitaxel; Pancreatic Neoplasms; Pantothenic Acid; Plant Extracts; Solutions; Vitamin B 12; Vitamin B 6; Zinc Sulfate | 2019 |