Compounds > gemcitabine
Page last updated: 2024-08-24

gemcitabine and aphidicolin

gemcitabine has been researched along with aphidicolin in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (66.67)18.2507
2000's1 (16.67)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, P; Plunkett, W2
Ballal, K; Huang, P; Plunkett, W1
Huang, P; Plunkett, W; Robertson, LE; Wright, S1
Ostruszka, LJ; Shewach, DS1
Amsailale, R; Arts, A; Bontemps, F; Smal, C; Starczewska, E; Van Den Neste, E1

Other Studies

6 other study(ies) available for gemcitabine and aphidicolin

ArticleYear
Induction of apoptosis by gemcitabine.
    Seminars in oncology, 1995, Volume: 22, Issue:4 Suppl 11

    Topics: Aphidicolin; Apoptosis; Calcium; Carcinogens; Chelating Agents; Clone Cells; Deoxycytidine; DNA; Egtazic Acid; Enzyme Inhibitors; Flow Cytometry; Gemcitabine; Humans; Ribonucleotide Reductases; S Phase; Tetradecanoylphorbol Acetate

1995
Fludarabine- and gemcitabine-induced apoptosis: incorporation of analogs into DNA is a critical event.
    Cancer chemotherapy and pharmacology, 1995, Volume: 36, Issue:3

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Aphidicolin; Apoptosis; Cell Cycle; Cell Line; Cell Membrane; Deoxycytidine; DNA Replication; DNA, Neoplasm; Gemcitabine; Humans; Kinetics; T-Lymphocytes; Time Factors; Tumor Cells, Cultured; Vidarabine

1995
Biochemical characterization of the protein activity responsible for high molecular weight DNA fragmentation during drug-induced apoptosis.
    Cancer research, 1997, Aug-15, Volume: 57, Issue:16

    Topics: Antineoplastic Agents; Aphidicolin; Apoptosis; Cell Fusion; Cell Line; Cysteine Endopeptidases; Deoxycytidine; DNA Fragmentation; DNA, Neoplasm; Electrophoresis, Gel, Pulsed-Field; Gemcitabine; Humans; In Vitro Techniques; Molecular Weight; Nucleosomes; Vidarabine

1997
High molecular weight DNA fragmentation: a critical event in nucleoside analogue-induced apoptosis in leukemia cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:9

    Topics: Antineoplastic Combined Chemotherapy Protocols; Aphidicolin; Apoptosis; Chelating Agents; Deoxycytidine; DNA Fragmentation; DNA, Neoplasm; Egtazic Acid; Enzyme Inhibitors; Gemcitabine; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Molecular Weight; Tumor Cells, Cultured; Vidarabine

1995
The role of DNA synthesis inhibition in the cytotoxicity of 2',2'-difluoro-2'-deoxycytidine.
    Cancer chemotherapy and pharmacology, 2003, Volume: 52, Issue:4

    Topics: Antineoplastic Agents; Aphidicolin; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Deoxycytidine; DNA, Neoplasm; Enzyme Inhibitors; Gemcitabine; Glioblastoma; Humans; Hydroxyurea; Nucleic Acid Synthesis Inhibitors; Pyrimidine Nucleosides; Ribonucleotide Reductases

2003
Phosphorylation of deoxycytidine kinase on Ser-74: impact on kinetic properties and nucleoside analog activation in cancer cells.
    Biochemical pharmacology, 2012, Jul-01, Volume: 84, Issue:1

    Topics: Antineoplastic Agents; Aphidicolin; Biotransformation; Cell Line, Tumor; Cell Survival; Cladribine; Deoxycytidine; Deoxycytidine Kinase; Enzyme Activation; Gemcitabine; HCT116 Cells; HT29 Cells; Humans; Kinetics; Mutation; Phosphorylation; Purine Nucleosides; Pyrimidine Nucleosides; Serine; Structure-Activity Relationship; Substrate Specificity; Vidarabine

2012