Page last updated: 2024-08-24

gemcitabine and adenosine

gemcitabine has been researched along with adenosine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (7.14)29.6817
2010's10 (71.43)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Hong, J; Johnson, ZL; Kwon, DY; Lee, JH; Lee, K; Lee, M; Lee, SY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Džubák, P; Gurská, S; Hajdúch, M; Hejtmánková, K; Hocek, M; Lišková, B; Oždian, T; Pohl, R; Smoleń, S; Tichý, M; Tloušt'ová, E1
Džubák, P; Frydrych, I; Gurská, S; Hajdúch, M; Hocek, M; Khalid, NU; Klepetářová, B; Laposa, RR; Lišková, B; Mertlíková-Kaiserová, H; Perlíková, P; Pohl, R; Poštová Slavětínská, L; Smoleń, S; Táborská, N; Tichý, M; Tloušt'ová, E; Tokarenko, A; Wenren, Y; Znojek, P1
Barron, G; Cass, CE; Damaraju, VL; Mowles, D; Peng, Y; Robins, MJ; Tackaberry, T; Young, JD1
Avan, A; Crea, F; Danesi, R; Funel, N; Galvani, E; Giovannetti, E; Honeywell, RJ; Marquez, VE; Paolicchi, E; Peters, GJ1
Bhutia, YD; Cho, JH; Chu, CK; Davis, F; Dhar, S; Govindarajan, R; Hung, SW; Marrache, S; Mody, H; Zastre, J1
Coe, IR; Naydenova, Z; Ramadan, A; Rose, JB; Stevanovic, K1
Baba, H; Beppu, T; Hashimoto, D; Hayashi, H; Kuroki, H; Mima, K; Nakagawa, S; Okabe, H; Sakamoto, K; Sakamoto, Y; Tokunaga, R; Yokoyama, N1
Cruz-Monserrate, Z; Govindarajan, R; Griffin, J; Hung, SW; Mody, HR; Pathak, RK1
Gu, HY; Hu, C; Huang, ZD; Lin, LL; Liu, ZZ; Wei, RX1
Chen, S; Chen, ZW; Hu, JF; Huang, L; Huang, Y; Liao, CY; Pan, JJ; Shen, BY; Tian, YF; Wang, YD; Wang, ZW; Yang, C; Zhang, JQ1
Guo, Z; Huang, Y; Lai, S; Li, T; Lin, C; Wang, Y; Weng, S; Zhang, X1

Reviews

1 review(s) available for gemcitabine and adenosine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

13 other study(ies) available for gemcitabine and adenosine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters.
    eLife, 2014, Jul-31, Volume: 3

    Topics: Animals; Bacterial Proteins; Binding Sites; Biological Transport; Crystallography, X-Ray; Deoxycytidine; Female; Gemcitabine; Gene Expression; Humans; Kinetics; Membrane Transport Proteins; Molecular Docking Simulation; Nucleoside Transport Proteins; Oocytes; Protein Binding; Quantitative Structure-Activity Relationship; Recombinant Proteins; Ribavirin; Substrate Specificity; Thermodynamics; Uridine; Vibrio cholerae; Xenopus laevis

2014
Synthesis and Cytostatic and Antiviral Profiling of Thieno-Fused 7-Deazapurine Ribonucleosides.
    Journal of medicinal chemistry, 2017, 03-23, Volume: 60, Issue:6

    Topics: Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Hepacivirus; Hepatitis C; Humans; Neoplasms; Purines; Ribonucleosides

2017
Synthesis and Cytotoxic and Antiviral Profiling of Pyrrolo- and Furo-Fused 7-Deazapurine Ribonucleosides.
    Journal of medicinal chemistry, 2018, 10-25, Volume: 61, Issue:20

    Topics: Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Chemistry Techniques, Synthetic; Furans; Humans; Purines; Pyrroles; Ribonucleosides; Structure-Activity Relationship

2018
Improved syntheses of 5'-S-(2-aminoethyl)-6-N-(4-nitrobenzyl)-5'-thioadenosine (SAENTA), analogues, and fluorescent probe conjugates: analysis of cell-surface human equilibrative nucleoside transporter 1 (hENT1) levels for prediction of the antitumor effi
    Journal of medicinal chemistry, 2010, Aug-26, Volume: 53, Issue:16

    Topics: Adenosine; Animals; Antineoplastic Agents; Cell Line, Tumor; Deoxycytidine; Equilibrative Nucleoside Transporter 1; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Gemcitabine; Humans; Mice; Oocytes; Protein Binding; Stereoisomerism; Structure-Activity Relationship; Thioinosine; Thionucleosides; Xenopus; Yeasts

2010
Molecular mechanisms involved in the synergistic interaction of the EZH2 inhibitor 3-deazaneplanocin A with gemcitabine in pancreatic cancer cells.
    Molecular cancer therapeutics, 2012, Volume: 11, Issue:8

    Topics: AC133 Antigen; Adenosine; Antigens, CD; Antimetabolites, Antineoplastic; Apoptosis; Cadherins; Carcinoma, Pancreatic Ductal; Cell Cycle; Cell Line, Tumor; Cell Movement; Deoxycytidine; Drug Synergism; Enhancer of Zeste Homolog 2 Protein; Equilibrative Nucleoside Transporter 1; Gemcitabine; Gene Expression; Gene Expression Regulation, Neoplastic; Glycoproteins; Humans; Membrane Transport Proteins; Pancreatic Neoplasms; Peptides; Polycomb Repressive Complex 2; Spheroids, Cellular; Tumor Cells, Cultured

2012
Pharmacological reversal of histone methylation presensitizes pancreatic cancer cells to nucleoside drugs: in vitro optimization and novel nanoparticle delivery studies.
    PloS one, 2013, Volume: 8, Issue:8

    Topics: Adenosine; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Cells, Cultured; Delayed-Action Preparations; Deoxycytidine; DNA Methylation; Drug Delivery Systems; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Gemcitabine; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Humans; Nanoparticles; Nucleosides; Pancreatic Neoplasms; Xenopus

2013
The adenosine transporter, ENT1, in cardiomyocytes is sensitive to inhibition by ethanol in a kinase-dependent manner: implications for ethanol-dependent cardioprotection and nucleoside analog drug cytotoxicity.
    Purinergic signalling, 2014, Volume: 10, Issue:2

    Topics: Adenosine; Animals; Antimetabolites, Antineoplastic; Cell Line; Cell Survival; Central Nervous System Depressants; Deoxycytidine; Equilibrative Nucleoside Transporter 1; Ethanol; Gemcitabine; Humans; Mice; Mice, Knockout; Myocytes, Cardiac; Protein Kinase C-epsilon

2014
Epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A inhibits the growth of cholangiocarcinoma cells.
    Oncology reports, 2014, Volume: 31, Issue:2

    Topics: Adenosine; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cell Line, Tumor; Cell Proliferation; Cholangiocarcinoma; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p27; Deoxycytidine; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Epigenesis, Genetic; G1 Phase Cell Cycle Checkpoints; Gemcitabine; Humans; Polycomb Repressive Complex 2; RNA Interference; RNA, Small Interfering

2014
miR-202 Diminishes TGFβ Receptors and Attenuates TGFβ1-Induced EMT in Pancreatic Cancer.
    Molecular cancer research : MCR, 2017, Volume: 15, Issue:8

    Topics: Adenosine; Animals; Capecitabine; Cell Line, Tumor; Deoxycytidine; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Lentivirus; Mice; MicroRNAs; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type I; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays

2017
m6A Modification Patterns With Distinct Immunity, Metabolism, and Stemness Characteristics in Soft Tissue Sarcoma.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adenosine; Antineoplastic Agents; Deoxycytidine; DNA Copy Number Variations; DNA Methylation; Docetaxel; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Immunotherapy; Kaplan-Meier Estimate; Sarcoma

2021
SRSF3-mediated regulation of N6-methyladenosine modification-related lncRNA ANRIL splicing promotes resistance of pancreatic cancer to gemcitabine.
    Cell reports, 2022, 05-10, Volume: 39, Issue:6

    Topics: Adenosine; Alternative Splicing; Deoxycytidine; DNA; Gemcitabine; Humans; Pancreatic Neoplasms; RNA, Long Noncoding; Serine-Arginine Splicing Factors

2022
METTL3 enhances pancreatic ductal adenocarcinoma progression and gemcitabine resistance through modifying DDX23 mRNA N6 adenosine methylation.
    Cell death & disease, 2023, 03-28, Volume: 14, Issue:3

    Topics: Adenosine; Animals; Carcinoma, Pancreatic Ductal; DEAD-box RNA Helicases; Gemcitabine; Humans; Lung Neoplasms; Methylation; Methyltransferases; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; RNA, Messenger

2023