gemcitabine has been researched along with 8,11,14-eicosatrienoic acid in 2 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brooks, A; Guo, B; Miskimins, KW; Qian, SY; Xu, Y; Yang, X | 1 |
| Gao, D; Qian, SY; Xu, Y; Yang, L; Yang, X | 1 |
2 other study(ies) available for gemcitabine and 8,11,14-eicosatrienoic acid
| Article | Year |
|---|---|
Knockdown delta-5-desaturase promotes the formation of a novel free radical byproduct from COX-catalyzed ω-6 peroxidation to induce apoptosis and sensitize pancreatic cancer cells to chemotherapy drugs.
Topics: 8,11,14-Eicosatrienoic Acid; Antineoplastic Agents; Apoptosis; Biocatalysis; Caprylates; Cell Line, Tumor; Cyclooxygenase 2; Delta-5 Fatty Acid Desaturase; Deoxycytidine; Drug Resistance, Neoplasm; Fatty Acid Desaturases; Free Radicals; Gemcitabine; Gene Knockdown Techniques; Humans; Lipid Peroxidation; Pancreatic Neoplasms | 2016 |
Dihomo-γ-linolenic acid inhibits growth of xenograft tumors in mice bearing human pancreatic cancer cells (BxPC-3) transfected with delta-5-desaturase shRNA.
Topics: 8,11,14-Eicosatrienoic Acid; Animals; Antineoplastic Agents; Apoptosis; Biomarkers; Cell Line, Tumor; Cell Proliferation; Delta-5 Fatty Acid Desaturase; Deoxycytidine; Disease Models, Animal; Drug Synergism; Fatty Acid Desaturases; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Metastasis; Neoplasm Staging; Pancreatic Neoplasms; RNA Interference; RNA, Small Interfering; Xenograft Model Antitumor Assays | 2019 |