gemcitabine has been researched along with 2'-deoxycytidine 5'-triphosphate in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (75.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 1 (8.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Plunkett, W; Xu, YZ | 1 |
| Chubb, S; Grindey, GB; Hertel, LW; Huang, P; Plunkett, W | 1 |
| Gandhi, V; Heinemann, V; Huang, P; Plunkett, W; Xu, YZ | 1 |
| Chubb, S; Grindey, GB; Heinemann, V; Hertel, LW; Plunkett, W; Sen, A; Xu, YZ | 1 |
| Heinemann, V; Issels, RD; Plunkett, W; Schulz, L | 1 |
| Cuddy, DP; Ross, DD | 1 |
| Bouffard, DY; Laliberté, J; Momparler, RL | 1 |
| Guechev, A; Loves, WJ; Peters, GJ; Pinedo, HM; Postmus, PE; Smid, K; van Moorsel, CJ; Veerman, G; Vermorken, JB | 1 |
| Goan, YG; Hu, E; Mi, S; Yen, Y; Zhou, B | 1 |
| Jiang, H; Li, L; Plunkett, W; Shen, Y; Yang, LY | 1 |
| Bergman, AM; Eijk, PP; Hubeek, I; Peters, GJ; Ruiz van Haperen, VW; Smid, K; van den Ijssel, P; Veerman, G; Ylstra, B | 1 |
| Fantaccini, G; Kahramanoğullari, O; Lecca, P; Morpurgo, D; Priami, C | 1 |
12 other study(ies) available for gemcitabine and 2'-deoxycytidine 5'-triphosphate
| Article | Year |
|---|---|
Modulation of deoxycytidylate deaminase in intact human leukemia cells. Action of 2',2'-difluorodeoxycytidine.
Topics: Antimetabolites, Antineoplastic; Carbon Radioisotopes; Cell Extracts; Chromatography, High Pressure Liquid; Cytidine Deaminase; DCMP Deaminase; Deoxycytidine; Deoxycytosine Nucleotides; Gemcitabine; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Thymine Nucleotides; Tumor Cells, Cultured | 1992 |
Action of 2',2'-difluorodeoxycytidine on DNA synthesis.
Topics: Antimetabolites, Antineoplastic; Base Sequence; Cells, Cultured; Cytarabine; Deoxycytidine; Deoxycytidine Monophosphate; Deoxycytosine Nucleotides; DNA; Gemcitabine; Humans; Molecular Sequence Data; RNA | 1991 |
Metabolism and action of 2',2'-difluorodeoxycytidine: self-potentiation of cytotoxicity.
Topics: Arabinofuranosylcytosine Triphosphate; Base Sequence; Cell Line; Cell Survival; DCMP Deaminase; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyribonucleotides; DNA Polymerase II; Gemcitabine; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Sequence Data; Oligodeoxyribonucleotides; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Tumor Stem Cell Assay | 1991 |
Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.
Topics: Cell Line; Cytidine; Deoxycytidine; Deoxycytosine Nucleotides; DNA; Gemcitabine; Humans; Hydroxyurea; Oxidation-Reduction; Ribonucleoside Diphosphate Reductase; Ribonucleotides; Thymine Nucleotides | 1990 |
Gemcitabine: a modulator of intracellular nucleotide and deoxynucleotide metabolism.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Carbon-Nitrogen Ligases; CHO Cells; Cricetinae; Cytidine Triphosphate; Deoxycytidine; Deoxycytosine Nucleotides; Dinucleoside Phosphates; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gemcitabine; Ligases; Phosphorylation; Ribonucleotide Reductases; Ribonucleotides; RNA; Tissue Distribution | 1995 |
Molecular effects of 2',2'-difluorodeoxycytidine (Gemcitabine) on DNA replication in intact HL-60 cells.
Topics: Antimetabolites, Antineoplastic; Cell Death; Cytarabine; Deoxycytidine; Deoxycytosine Nucleotides; Deoxyguanine Nucleotides; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Stability; Gemcitabine; Humans; Hydrogen-Ion Concentration; Tumor Cells, Cultured | 1994 |
Kinetic studies on 2',2'-difluorodeoxycytidine (Gemcitabine) with purified human deoxycytidine kinase and cytidine deaminase.
Topics: Antimetabolites, Antineoplastic; Azepines; Cytidine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Gemcitabine; Half-Life; Humans; Kinetics; Tetrahydrouridine | 1993 |
Combination chemotherapy studies with gemcitabine and etoposide in non-small cell lung and ovarian cancer cell lines.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Deoxycytidine; Deoxycytosine Nucleotides; DNA Damage; Drug Synergism; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Ovarian Neoplasms; Tumor Cells, Cultured | 1999 |
Overexpression of ribonucleotide reductase as a mechanism of resistance to 2,2-difluorodeoxycytidine in the human KB cancer cell line.
Topics: Antimetabolites, Antineoplastic; Deoxyadenine Nucleotides; Deoxycytidine; Deoxycytosine Nucleotides; Drug Resistance, Neoplasm; Gemcitabine; Humans; KB Cells; Ribonucleotide Reductases | 1999 |
Expression of ERCC1 antisense RNA abrogates gemicitabine-mediated cytotoxic synergism with cisplatin in human colon tumor cells defective in mismatch repair but proficient in nucleotide excision repair.
Topics: Antineoplastic Agents; Base Pair Mismatch; Cell Survival; Cisplatin; Colonic Neoplasms; Deoxycytidine; Deoxycytosine Nucleotides; DNA; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Drug; Down-Regulation; Drug Synergism; Endonucleases; Gemcitabine; Gene Expression; Humans; Mutation; Proteins; RNA, Antisense; Tumor Cells, Cultured | 2000 |
In vivo induction of resistance to gemcitabine results in increased expression of ribonucleotide reductase subunit M1 as the major determinant.
Topics: Animals; Blotting, Western; Colonic Neoplasms; Cytidine Deaminase; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; Drug Resistance, Neoplasm; Female; Gemcitabine; Gene Expression Profiling; Mice; Mice, Inbred BALB C; Nucleoside Deaminases; Oligonucleotide Array Sequence Analysis; Protein Subunits; Ribonucleotide Reductases | 2005 |
Algorithmic modeling quantifies the complementary contribution of metabolic inhibitions to gemcitabine efficacy.
Topics: Algorithms; Computer Simulation; Deoxycytidine; Deoxycytidine Kinase; Deoxycytosine Nucleotides; DNA; Equilibrative Nucleoside Transporter 1; Gemcitabine; Humans; Models, Theoretical; Neoplasms; Ribonucleotide Reductases | 2012 |