gefitinib has been researched along with zm 447439 in 4 studies
| Studies (gefitinib) | Trials (gefitinib) | Recent Studies (post-2010) (gefitinib) | Studies (zm 447439) | Trials (zm 447439) | Recent Studies (post-2010) (zm 447439) |
|---|---|---|---|---|---|
| 5,231 | 566 | 2,919 | 25 | 0 | 17 |
| Protein | Taxonomy | gefitinib (IC50) | zm 447439 (IC50) |
|---|---|---|---|
| Aurora kinase A | Homo sapiens (human) | 0.1315 | |
| Epidermal growth factor receptor | Homo sapiens (human) | 0.11 | |
| Cyclin-dependent kinase 4 | Homo sapiens (human) | 0.039 | |
| G1/S-specific cyclin-D1 | Homo sapiens (human) | 0.039 | |
| Aurora kinase A | Mus musculus (house mouse) | 0.039 | |
| Aurora kinase B-A | Xenopus laevis (African clawed frog) | 0.045 | |
| Aurora kinase B | Homo sapiens (human) | 0.1213 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB | 1 |
| Cai, J; Cao, M; Chen, J; Hong, KH; Ji, M; Li, L; Wang, P; Wu, X; Zong, X | 1 |
| Das, D; Hong, J | 1 |
| Bansal, R; Malhotra, A | 1 |
2 review(s) available for gefitinib and zm 447439
| Article | Year |
|---|---|
Recent advancements of 4-aminoquinazoline derivatives as kinase inhibitors and their applications in medicinal chemistry.
Topics: Animals; Antineoplastic Agents; Chemistry Techniques, Synthetic; Humans; Neoplasms; Protein Kinase Inhibitors; Quinazolines | 2019 |
Therapeutic progression of quinazolines as targeted chemotherapeutic agents.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Enzyme Inhibitors; Humans; Molecular Structure; Neoplasms; Quinazolines | 2021 |
2 other study(ies) available for gefitinib and zm 447439
| Article | Year |
|---|---|
Navigating the kinome.
Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology | 2011 |
Discovery of 4-aminoquinazoline--urea derivatives as Aurora kinase inhibitors with antiproliferative activity.
Topics: Antineoplastic Agents; Aurora Kinase A; Aurora Kinase B; Benzamides; Binding Sites; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Evaluation, Preclinical; Enzyme Activation; Humans; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Quinazolines; Structure-Activity Relationship; Urea | 2014 |