Page last updated: 2024-09-03

gefitinib and y 27632

gefitinib has been researched along with y 27632 in 2 studies

Compound Research Comparison

Studies (gefitinib)	Trials (gefitinib)	Recent Studies (post-2010) (gefitinib)	Studies (y 27632)	Trials (y 27632)	Recent Studies (post-2010) (y 27632)
5,231	566	2,919	1,924	3	891

Protein Interaction Comparison

Protein	Taxonomy	y 27632 (IC50)
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	Bos taurus (cattle)	6
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	Bos taurus (cattle)	6
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	Bos taurus (cattle)	6
Chain I, cAMP-dependent protein kinase inhibitor alpha	synthetic construct	6
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	Bos taurus (cattle)	6
Chain A, cAMP-dependent protein kinase, alpha-catalytic subunit	Bos taurus (cattle)	6
Chain I, cAMP-dependent protein kinase inhibitor alpha	synthetic construct	6
Rho-associated protein kinase 2	Homo sapiens (human)	0.1942
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	8.3
cAMP-dependent protein kinase catalytic subunit alpha	Bos taurus (cattle)	6.1
C-C motif chemokine 2	Homo sapiens (human)	2.6303
Rho-associated protein kinase 1	Homo sapiens (human)	0.3713
Serine/threonine-protein kinase N2	Homo sapiens (human)	0.6
Rho-associated protein kinase 2	Bos taurus (cattle)	6.1
Rho-associated protein kinase 2	Rattus norvegicus (Norway rat)	0.8

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M	1
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1

Other Studies

2 other study(ies) available for gefitinib and y 27632

Article	Year
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51 Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases	2007
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013

Article

Year

A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013