Page last updated: 2024-09-03

gefitinib and vinorelbine

gefitinib has been researched along with vinorelbine in 5 studies

Compound Research Comparison

Studies
(gefitinib)
Trials
(gefitinib)
Recent Studies (post-2010)
(gefitinib)
Studies
(vinorelbine)
Trials
(vinorelbine)
Recent Studies (post-2010) (vinorelbine)
5,2315662,91950031

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)vinorelbine (IC50)
Tubulin beta-4A chainHomo sapiens (human)1.35
CholinesteraseHomo sapiens (human)0.7
Tubulin beta chainHomo sapiens (human)1.35
Cytochrome P450 3A4Homo sapiens (human)1
Tubulin alpha-3C chainHomo sapiens (human)1.35
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.7
Substance-K receptorHomo sapiens (human)1.6062
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.7
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.7
Tubulin alpha-1B chainHomo sapiens (human)1.35
Tubulin alpha-4A chainHomo sapiens (human)1.35
Tubulin beta-4B chainHomo sapiens (human)1.35
Tubulin beta-3 chainHomo sapiens (human)1.35
Tubulin beta-2A chainHomo sapiens (human)1.35
Tubulin beta-8 chainHomo sapiens (human)1.35
Tubulin alpha-3E chainHomo sapiens (human)1.35
Tubulin alpha-1A chainHomo sapiens (human)1.35
Tubulin alpha-1C chainHomo sapiens (human)1.35
Tubulin beta-6 chainHomo sapiens (human)1.35
Tubulin beta-2B chainHomo sapiens (human)1.35
Tubulin beta-1 chainHomo sapiens (human)1.35

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Capuzzi, SJ; Fisher, EG; García-Sastre, A; He, S; Li, H; Martínez-Romero, C; Muratov, EN; Qiu, X; Shinn, P; Sun, W; Tawa, G; Tropsha, A; Xu, M; Zheng, W; Zhu, W1

Reviews

1 review(s) available for gefitinib and vinorelbine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for gefitinib and vinorelbine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:4

    Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water

2010
Computer-Aided Discovery and Characterization of Novel Ebola Virus Inhibitors.
    Journal of medicinal chemistry, 2018, 04-26, Volume: 61, Issue:8

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Drug Discovery; Drug Evaluation, Preclinical; Ebolavirus; HeLa Cells; Humans; Molecular Structure; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Virus Internalization

2018