Compounds > gefitinib
Page last updated: 2024-09-03

gefitinib and valdecoxib

gefitinib has been researched along with valdecoxib in 3 studies

Compound Research Comparison

Studies
(gefitinib)		Trials
(gefitinib)		Recent Studies (post-2010)
(gefitinib)		Studies
(valdecoxib)		Trials
(valdecoxib)		Recent Studies (post-2010) (valdecoxib)
5,2315662,9193757186

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)valdecoxib (IC50)
Cytochrome c oxidase subunit 2Homo sapiens (human)1.1
Carbonic anhydrase 1Homo sapiens (human)0.1915
Carbonic anhydrase 2Homo sapiens (human)1.0086
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.927
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.927
Prostaglandin G/H synthase 2Homo sapiens (human)0.0631
Carbonic anhydrase 9Homo sapiens (human)0.027
Carbonic anhydrase 4Bos taurus (cattle)0.2658

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dalvie, D; Loi, CM; Smith, DA1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for gefitinib and valdecoxib

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

2 other study(ies) available for gefitinib and valdecoxib

ArticleYear
Which metabolites circulate?
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:5

    Topics: Humans; Metabolic Clearance Rate; Pharmaceutical Preparations

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013