gefitinib has been researched along with thiourea in 3 studies
| Studies (gefitinib) | Trials (gefitinib) | Recent Studies (post-2010) (gefitinib) | Studies (thiourea) | Trials (thiourea) | Recent Studies (post-2010) (thiourea) |
|---|---|---|---|---|---|
| 5,231 | 566 | 2,919 | 6,959 | 46 | 1,737 |
| Protein | Taxonomy | gefitinib (IC50) | thiourea (IC50) |
|---|---|---|---|
| Urease | Canavalia ensiformis (jack bean) | 0.56 | |
| Serine-protein kinase ATM | Homo sapiens (human) | 0.2 | |
| Serine/threonine-protein kinase ATR | Homo sapiens (human) | 0.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M | 1 |
| Fu, L; Li, J; Li, L; Liu, H; Luo, X; Mei, C; Xiong, X | 1 |
| Bierbach, U; Day, CS; Gueble, MJ; Kucera, GL; Pickard, AJ; Qiao, X; Yang, M | 1 |
3 other study(ies) available for gefitinib and thiourea
| Article | Year |
|---|---|
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases | 2007 |
Antitumor activity of a new N-substituted thiourea derivative, an EGFR signaling-targeted inhibitor against a panel of human lung cancer cell lines.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; DNA; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Molecular Structure; Protein Kinase Inhibitors; Quinazolines; Signal Transduction; Thiourea | 2008 |
Synthesis, reactivity, and biological activity of gold(I) complexes modified with thiourea-functionalized tyrosine kinase inhibitors.
Topics: Afatinib; Cell Line; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; Dose-Response Relationship, Drug; Gefitinib; Gold; Humans; Inhibitory Concentration 50; Protein Kinase Inhibitors; Quinazolines; Thiourea | 2015 |