Page last updated: 2024-09-03

gefitinib and tae226

gefitinib has been researched along with tae226 in 2 studies

Compound Research Comparison

Studies
(gefitinib)
Trials
(gefitinib)
Recent Studies (post-2010)
(gefitinib)
Studies
(tae226)
Trials
(tae226)
Recent Studies (post-2010) (tae226)
5,2315662,91965049

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)tae226 (IC50)
Chain A, FOCAL ADHESION KINASE 1Gallus gallus (chicken)0.0062
Chain A, FOCAL ADHESION KINASE 1Gallus gallus (chicken)0.0062
Chain A, FOCAL ADHESION KINASE 1Gallus gallus (chicken)0.0062
Chain A, FOCAL ADHESION KINASE 1Gallus gallus (chicken)0.0062
Aurora kinase AHomo sapiens (human)0.004
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)0.86
Epidermal growth factor receptorHomo sapiens (human)0.55
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.71
Insulin receptorHomo sapiens (human)0.036
Insulin-like growth factor 1 receptorHomo sapiens (human)0.1205
Platelet-derived growth factor receptor betaHomo sapiens (human)2.6
Fibroblast growth factor receptor 1Homo sapiens (human)0.75
Focal adhesion kinase 1Homo sapiens (human)0.3135
ALK tyrosine kinase receptorHomo sapiens (human)0.0275

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Asano, H; Hatakeyama, S; Jida, M; Kawahara, E; Kiura, K; Kubo, T; Miyoshi, S; Naomoto, Y; Otani, H; Sakaguchi, M; Soh, J; Takaoka, M; Toyooka, S; Tsukuda, K; Ueno, T; Yamamoto, H1

Other Studies

2 other study(ies) available for gefitinib and tae226

ArticleYear
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
TAE226, a Bis-Anilino Pyrimidine Compound, Inhibits the EGFR-Mutant Kinase Including T790M Mutant to Show Anti-Tumor Effect on EGFR-Mutant Non-Small Cell Lung Cancer Cells.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Drug Resistance, Neoplasm; ErbB Receptors; Focal Adhesion Protein-Tyrosine Kinases; Gefitinib; Humans; Lung Neoplasms; Mice; Morpholines; Mutation; Protein Binding; Protein Interaction Domains and Motifs; Protein Kinase Inhibitors; Quinazolines; Receptor, IGF Type 1; Xenograft Model Antitumor Assays

2015