Page last updated: 2024-09-03

gefitinib and sr 48692

gefitinib has been researched along with sr 48692 in 2 studies

Compound Research Comparison

Studies
(gefitinib)
Trials
(gefitinib)
Recent Studies (post-2010)
(gefitinib)
Studies
(sr 48692)
Trials
(sr 48692)
Recent Studies (post-2010) (sr 48692)
5,2315662,919203336

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)sr 48692 (IC50)
Neurotensin receptor type 1Rattus norvegicus (Norway rat)0.082
Neurotensin receptor type 1Homo sapiens (human)0.0415
SortilinHomo sapiens (human)0.238

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Chan, DC; Jensen, RT; Mantey, SA; Moody, TW; Moreno, P1

Other Studies

2 other study(ies) available for gefitinib and sr 48692

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
SR48692 inhibits non-small cell lung cancer proliferation in an EGF receptor-dependent manner.
    Life sciences, 2014, Mar-28, Volume: 100, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Gefitinib; Gene Knockdown Techniques; Humans; Lung Neoplasms; Phosphorylation; Protein Processing, Post-Translational; Pyrazoles; Quinazolines; Quinolines; Receptors, Neurotensin; RNA, Small Interfering; Transcriptional Activation; Transforming Growth Factor alpha

2014