Page last updated: 2024-09-03

gefitinib and sincalide

gefitinib has been researched along with sincalide in 3 studies

Compound Research Comparison

Studies (gefitinib)	Trials (gefitinib)	Recent Studies (post-2010) (gefitinib)	Studies (sincalide)	Trials (sincalide)	Recent Studies (post-2010) (sincalide)
5,231	566	2,919	4,015	72	533

Protein Interaction Comparison

Protein	Taxonomy	sincalide (IC50)
Cholecystokinin receptor type A	Rattus norvegicus (Norway rat)	0.0006
Cholecystokinin receptor type A	Homo sapiens (human)	0.0006
Gastrin/cholecystokinin type B receptor	Homo sapiens (human)	0.001
Gastrin/cholecystokinin type B receptor	Mus musculus (house mouse)	0.0008
Cholecystokinin receptor type A	Cavia porcellus (domestic guinea pig)	0.0004

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (66.67)	24.3611
2020's	1 (33.33)	2.80

Authors

Authors	Studies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Chen, JY; Jiang, Z; Long, F; Ren, YG; Tang, JC; Zhao, J	1
Chen, H; Liao, K; Zi, Y	1

Reviews

1 review(s) available for gefitinib and sincalide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

2 other study(ies) available for gefitinib and sincalide

Article	Year
Shikonin enhances sensitization of gefitinib against wild-type EGFR non-small cell lung cancer via inhibition PKM2/stat3/cyclinD1 signal pathway. Life sciences, 2018, Jul-01, Volume: 204 Topics: A549 Cells; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Line, Tumor; Cell Survival; Cyclin D1; Drug Synergism; ErbB Receptors; Gefitinib; Humans; Immunohistochemistry; Lung Neoplasms; Membrane Proteins; Mice; Mice, Nude; Naphthoquinones; Quinazolines; Signal Transduction; Sincalide; STAT3 Transcription Factor; Thyroid Hormone-Binding Proteins; Thyroid Hormones	2018
[Cigarette Smoke Induces Gefitinib Resistance in NSCLC Cells  via ROS/Sirt3/SOD2 Pathway]. Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2023, Apr-20, Volume: 26, Issue:4 Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cigarette Smoking; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Reactive Oxygen Species; Sincalide; Sirtuin 3	2023

Article

Year

Shikonin enhances sensitization of gefitinib against wild-type EGFR non-small cell lung cancer via inhibition PKM2/stat3/cyclinD1 signal pathway.

Life sciences, 2018, Jul-01, Volume: 204

Topics: A549 Cells; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Line, Tumor; Cell Survival; Cyclin D1; Drug Synergism; ErbB Receptors; Gefitinib; Humans; Immunohistochemistry; Lung Neoplasms; Membrane Proteins; Mice; Mice, Nude; Naphthoquinones; Quinazolines; Signal Transduction; Sincalide; STAT3 Transcription Factor; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2018

[Cigarette Smoke Induces Gefitinib Resistance in NSCLC Cells  via ROS/Sirt3/SOD2 Pathway].

Zhongguo fei ai za zhi = Chinese journal of lung cancer, 2023, Apr-20, Volume: 26, Issue:4

Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cigarette Smoking; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Humans; Lung Neoplasms; Reactive Oxygen Species; Sincalide; Sirtuin 3

2023