gefitinib has been researched along with sertraline in 4 studies
| Studies (gefitinib) | Trials (gefitinib) | Recent Studies (post-2010) (gefitinib) | Studies (sertraline) | Trials (sertraline) | Recent Studies (post-2010) (sertraline) |
|---|---|---|---|---|---|
| 5,231 | 566 | 2,919 | 3,480 | 1,028 | 1,329 |
| Protein | Taxonomy | gefitinib (IC50) | sertraline (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.083 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.9848 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 2.7675 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 2.6309 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 0.8 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.5073 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.2888 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 1.4 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 1.2882 | |
| Angiotensin-converting enzyme | Oryctolagus cuniculus (rabbit) | 8.3173 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.1814 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 4.477 | |
| D | Rattus norvegicus (Norway rat) | 0.26 | |
| D(3) dopamine receptor | Rattus norvegicus (Norway rat) | 0.26 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 0.8783 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.825 | |
| D(1B) dopamine receptor | Rattus norvegicus (Norway rat) | 0.26 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 2.7409 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.083 | |
| D(4) dopamine receptor | Rattus norvegicus (Norway rat) | 0.26 | |
| 3-oxo-5-alpha-steroid 4-dehydrogenase 2 | Homo sapiens (human) | 0.8 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.0016 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.1743 | |
| Melanocortin receptor 5 | Homo sapiens (human) | 4.598 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 0.655 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 3.3935 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 0.26 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.2175 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 8.3173 | |
| Nuclear receptor subfamily 3 group C member 3 | Bos taurus (cattle) | 8.3173 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 0.0697 | |
| Transporter | Rattus norvegicus (Norway rat) | 0.26 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Baskaran, S; Forsberg Nilsson, K; Gerlee, P; Häggblad, M; Hansson, C; Karlsson-Lindahl, L; Kling, T; Lundgren, B; Martens, U; Monsefi, N; Nelander, S; Olsson, M; Schmidt, L; Uhrbom, L; Westermark, B | 1 |
1 review(s) available for gefitinib and sertraline
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 other study(ies) available for gefitinib and sertraline
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions.
Topics: Antineoplastic Combined Chemotherapy Protocols; Carbazoles; Cell Line, Tumor; Drug Interactions; Gefitinib; Glioblastoma; Humans; Quinazolines; Sertraline; Stilbenes | 2013 |