Compounds > gefitinib
Page last updated: 2024-09-03

gefitinib and sertindole

gefitinib has been researched along with sertindole in 1 studies

Compound Research Comparison

Studies
(gefitinib)		Trials
(gefitinib)		Recent Studies (post-2010)
(gefitinib)		Studies
(sertindole)		Trials
(sertindole)		Recent Studies (post-2010) (sertindole)
5,2315662,9192763467

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)sertindole (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)8.9
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)7.6
ATP-dependent translocase ABCB1Homo sapiens (human)6.5
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0004
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0004
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0034
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)2
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)0.0034
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0004
Sodium channel protein type 1 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 4 subunit alphaHomo sapiens (human)2.3
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)0.0034
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0041
Sodium channel protein type 7 subunit alphaHomo sapiens (human)2.3
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)7.6
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.0109
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)7.6
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)7.6
Sodium channel protein type 5 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 9 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 2 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 3 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 11 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 8 subunit alphaHomo sapiens (human)2.3
Sodium channel protein type 10 subunit alphaHomo sapiens (human)2.3

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1

Other Studies

1 other study(ies) available for gefitinib and sertindole

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013