gefitinib has been researched along with rucaparib in 3 studies
| Studies (gefitinib) | Trials (gefitinib) | Recent Studies (post-2010) (gefitinib) | Studies (rucaparib) | Trials (rucaparib) | Recent Studies (post-2010) (rucaparib) |
|---|---|---|---|---|---|
| 5,231 | 566 | 2,919 | 236 | 36 | 220 |
| Protein | Taxonomy | gefitinib (IC50) | rucaparib (IC50) |
|---|---|---|---|
| Poly [ADP-ribose] polymerase tankyrase-1 | Homo sapiens (human) | 0.0847 | |
| Poly [ADP-ribose] polymerase 1 | Homo sapiens (human) | 0.0418 | |
| Protein mono-ADP-ribosyltransferase PARP14 | Homo sapiens (human) | 8.8713 | |
| Protein mono-ADP-ribosyltransferase PARP10 | Homo sapiens (human) | 1.4333 | |
| Protein mono-ADP-ribosyltransferase PARP12 | Homo sapiens (human) | 6.6285 | |
| Poly [ADP-ribose] polymerase tankyrase-2 | Homo sapiens (human) | 0.4523 | |
| Poly [ADP-ribose] polymerase 2 | Homo sapiens (human) | 0.0497 | |
| Protein mono-ADP-ribosyltransferase PARP4 | Homo sapiens (human) | 0.8354 | |
| Protein mono-ADP-ribosyltransferase PARP3 | Homo sapiens (human) | 0.4597 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB | 1 |
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Beijnen, JH; Durmus, S; Schellens, JH; Schinkel, AH; Sparidans, RW | 1 |
3 other study(ies) available for gefitinib and rucaparib
| Article | Year |
|---|---|
Navigating the kinome.
Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology | 2011 |
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
Liquid chromatography-tandem mass spectrometric assay for the PARP inhibitor rucaparib in plasma.
Topics: Acetonitriles; Animals; Area Under Curve; Calibration; Chromatography, Liquid; Edetic Acid; Female; Gefitinib; Indoles; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Protein Kinase Inhibitors; Quality Control; Quinazolines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2014 |