Page last updated: 2024-09-03

gefitinib and raloxifene

gefitinib has been researched along with raloxifene in 5 studies

Compound Research Comparison

Studies
(gefitinib)
Trials
(gefitinib)
Recent Studies (post-2010)
(gefitinib)
Studies
(raloxifene)
Trials
(raloxifene)
Recent Studies (post-2010) (raloxifene)
5,2315662,919128061

Protein Interaction Comparison

ProteinTaxonomygefitinib (IC50)raloxifene (IC50)
Phospholipase D2Homo sapiens (human)6.1333
Aldehyde oxidase 1Mus musculus (house mouse)0.5
Lysine-specific histone demethylase 1AHomo sapiens (human)2.08
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.178
Estrogen receptorHomo sapiens (human)0.0416
Estrogen receptorRattus norvegicus (Norway rat)0.0032
Tyrosine-protein kinase FynHomo sapiens (human)3.666
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.282
Alpha-2A adrenergic receptorHomo sapiens (human)1.664
Cytochrome P450 2C9 Homo sapiens (human)2
D(2) dopamine receptorHomo sapiens (human)1.174
Alpha-2B adrenergic receptorHomo sapiens (human)3.698
Alpha-2C adrenergic receptorHomo sapiens (human)0.738
Substance-K receptorHomo sapiens (human)3.989
D(1A) dopamine receptorHomo sapiens (human)3.864
AcetylcholinesteraseHomo sapiens (human)0.4
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.282
Alpha-1D adrenergic receptorHomo sapiens (human)0.973
5-hydroxytryptamine receptor 2AHomo sapiens (human)1.45
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.178
Adenosine receptor A2aHomo sapiens (human)2.111
Sodium-dependent serotonin transporterHomo sapiens (human)3.576
Mu-type opioid receptorHomo sapiens (human)1.176
D(3) dopamine receptorHomo sapiens (human)1.565
Delta-type opioid receptorHomo sapiens (human)6.644
Kappa-type opioid receptorHomo sapiens (human)1.602
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.355
Aldehyde oxidase 1Oryctolagus cuniculus (rabbit)0.008
Sodium-dependent dopamine transporter Homo sapiens (human)1.869
Aldehyde oxidaseHomo sapiens (human)0.0055
Platelet-activating factor acetylhydrolaseHomo sapiens (human)0.0003
Phospholipase D1Homo sapiens (human)4.9167
Aldehyde oxidase 1Macaca fascicularis (crab-eating macaque)0.5
Estrogen receptor betaRattus norvegicus (Norway rat)0.1584
Estrogen receptor betaHomo sapiens (human)0.3051
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.681
Aldehyde oxidase 1 Rattus norvegicus (Norway rat)1.1

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andricopulo, AD; Moda, TL; Montanari, CA1
Doak, AK; Prusiner, SB; Shoichet, BK; Wille, H1
Ekins, S; Williams, AJ; Xu, JJ1
Akhtar Siddiqui, J; Akhtar, T; Chakravarti, B; Chattopadhyay, N; Datta, D; Dhar Dwivedi, SK; Godbole, MM; Khan, K; Konwar, R; Kumar, A; Kumar, H; Lal, J; Mishra, DP; Pal, S; Rai, B; Rath, SK; Sanyal, S; Singh, AK; Thakur, R; Trivedi, AK; Yadav, M1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1

Reviews

1 review(s) available for gefitinib and raloxifene

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

4 other study(ies) available for gefitinib and raloxifene

ArticleYear
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Colloid formation by drugs in simulated intestinal fluid.
    Journal of medicinal chemistry, 2010, May-27, Volume: 53, Issue:10

    Topics: Buffers; Chemical Precipitation; Colloids; Intestine, Small; Light; Microscopy, Electron, Transmission; Pharmaceutical Preparations; Scattering, Radiation; Solubility

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Thioaryl naphthylmethanone oxime ether analogs as novel anticancer agents.
    Journal of medicinal chemistry, 2014, Oct-09, Volume: 57, Issue:19

    Topics: Animals; Antineoplastic Agents; Apoptosis; Benzhydryl Compounds; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; ErbB Receptors; Humans; Mice; Neoplasm Invasiveness; Neoplastic Stem Cells; Oximes; Signal Transduction; Structure-Activity Relationship

2014